{"id":"https://openalex.org/W4391509842","doi":"https://doi.org/10.1021/acsanm.3c06195","title":"Ameliorating Old Drugs with New Tricks in the Nano Realms","display_name":"Ameliorating Old Drugs with New Tricks in the Nano Realms","publication_year":2024,"publication_date":"2024-02-03","ids":{"openalex":"https://openalex.org/W4391509842","doi":"https://doi.org/10.1021/acsanm.3c06195"},"language":"en","primary_location":{"id":"doi:10.1021/acsanm.3c06195","doi":"https://doi.org/10.1021/acsanm.3c06195","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsanm.3c06195","pdf_url":null,"source":{"id":"https://openalex.org/S4210191493","display_name":"ACS Applied Nano Materials","issn_l":"2574-0970","issn":["2574-0970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Applied Nano Materials","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056850739","display_name":"Konika Choudhury","orcid":"https://orcid.org/0000-0002-1418-0482","observed_orcids":["https://orcid.org/0000-0002-1418-0482"]},"institutions":[{"id":"https://openalex.org/I1317621060","display_name":"Indian Institute of Technology Guwahati","ror":"https://ror.org/0022nd079","country_code":"IN","type":"education","lineage":["https://openalex.org/I1317621060"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Konika Choudhury","raw_affiliation_strings":["Centre for Nanotechnology, Indian Institute of Technology Guwahati, Guwahati 781039, India"],"raw_orcid":"https://orcid.org/0000-0002-1418-0482","affiliations":[{"raw_affiliation_string":"Centre for Nanotechnology, Indian Institute of Technology Guwahati, Guwahati 781039, India","institution_ids":["https://openalex.org/I1317621060"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014865113","display_name":"Siddhartha Sankar Ghosh","orcid":"https://orcid.org/0000-0002-7121-5610","observed_orcids":["https://orcid.org/0000-0002-7121-5610","https://orcid.org/0000-0002-5019-0936","https://orcid.org/0000-0002-9704-7600"]},"institutions":[{"id":"https://openalex.org/I1317621060","display_name":"Indian Institute of Technology Guwahati","ror":"https://ror.org/0022nd079","country_code":"IN","type":"education","lineage":["https://openalex.org/I1317621060"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Siddhartha Sankar Ghosh","raw_affiliation_strings":["Centre for Nanotechnology, Indian Institute of Technology Guwahati, Guwahati 781039, India","Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, India"],"raw_orcid":"https://orcid.org/0000-0002-7121-5610","affiliations":[{"raw_affiliation_string":"Centre for Nanotechnology, Indian Institute of Technology Guwahati, Guwahati 781039, India","institution_ids":["https://openalex.org/I1317621060"]},{"raw_affiliation_string":"Department of Biosciences and Bioengineering, Indian Institute of Technology Guwahati, Guwahati 781039, India","institution_ids":["https://openalex.org/I1317621060"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5014865113"],"corresponding_institution_ids":["https://openalex.org/I1317621060"],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":0.4714,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.44714309,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"7","issue":"4","first_page":"3564","last_page":"3579"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.9883000254631042,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14089","display_name":"Nanotechnology research and applications","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug-repurposing","display_name":"drug repurposing","score":0.9869999885559082},{"id":"https://openalex.org/keywords/nanomaterials","display_name":"nanomaterials","score":0.6949999928474426},{"id":"https://openalex.org/keywords/cancer-therapy","display_name":"cancer therapy","score":0.9430000185966492},{"id":"https://openalex.org/keywords/nanomedicine","display_name":"nanomedicine","score":0.7590000033378601},{"id":"https://openalex.org/keywords/drug-delivery","display_name":"drug delivery","score":0.9020000100135803},{"id":"https://openalex.org/keywords/drug-survival","display_name":"drug retention","score":0.7279999852180481},{"id":"https://openalex.org/keywords/toxicity-reduction","display_name":"toxicity reduction","score":0.8009999990463257},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.4099999964237213}],"concepts":[{"id":"https://openalex.org/C2780357685","wikidata":"https://www.wikidata.org/wiki/Q154357","display_name":"Nano-","level":2,"score":0.4103228747844696},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.40922656655311584},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.23262885212898254},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.13511425256729126},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.0574553906917572}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1021/acsanm.3c06195","doi":"https://doi.org/10.1021/acsanm.3c06195","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsanm.3c06195","pdf_url":null,"source":{"id":"https://openalex.org/S4210191493","display_name":"ACS Applied Nano Materials","issn_l":"2574-0970","issn":["2574-0970"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","norway-1","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Applied Nano Materials","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G282800862","display_name":null,"funder_award_id":"5 (1)/2022-NANO","funder_id":"https://openalex.org/F4320325255","funder_display_name":"Ministry of Electronics and Information technology"},{"id":"https://openalex.org/G2983061054","display_name":null,"funder_award_id":"5(1)/2021 - NANO","funder_id":"https://openalex.org/F4320325255","funder_display_name":"Ministry of Electronics and Information technology"},{"id":"https://openalex.org/G303454441","display_name":null,"funder_award_id":"BT/PR44695/NER/95/1880/2021","funder_id":"https://openalex.org/F4320320717","funder_display_name":"Department of Biotechnology, Ministry of Science and Technology, India"},{"id":"https://openalex.org/G3050281799","display_name":null,"funder_award_id":"BT /PR41449/ NER /95/1687/2020","funder_id":"https://openalex.org/F4320320717","funder_display_name":"Department of Biotechnology, Ministry of Science and Technology, India"},{"id":"https://openalex.org/G5929897061","display_name":null,"funder_award_id":"5/3/8/20/2019-ITR","funder_id":"https://openalex.org/F4320325255","funder_display_name":"Ministry of Electronics and Information technology"}],"funders":[{"id":"https://openalex.org/F4320320717","display_name":"Department of Biotechnology, Ministry of Science and Technology, India","ror":"https://ror.org/03tjsyq23"},{"id":"https://openalex.org/F4320325255","display_name":"Ministry of Electronics and Information technology","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":160,"referenced_works":["https://openalex.org/W585675451","https://openalex.org/W989479261","https://openalex.org/W1770290865","https://openalex.org/W1789224823","https://openalex.org/W1843302206","https://openalex.org/W1939933707","https://openalex.org/W1966631624","https://openalex.org/W1968029051","https://openalex.org/W1968101056","https://openalex.org/W1968423420","https://openalex.org/W1968583232","https://openalex.org/W1971018930","https://openalex.org/W1972441060","https://openalex.org/W1984162012","https://openalex.org/W1987483764","https://openalex.org/W1989353157","https://openalex.org/W1990879541","https://openalex.org/W1996830477","https://openalex.org/W2000181806","https://openalex.org/W2001239461","https://openalex.org/W2003154269","https://openalex.org/W2003474213","https://openalex.org/W2004109893","https://openalex.org/W2011690386","https://openalex.org/W2015512331","https://openalex.org/W2016409247","https://openalex.org/W2024787650","https://openalex.org/W2026822060","https://openalex.org/W2032993907","https://openalex.org/W2036559515","https://openalex.org/W2038428090","https://openalex.org/W2039759758","https://openalex.org/W2047368765","https://openalex.org/W2047568538","https://openalex.org/W2049671346","https://openalex.org/W2057053889","https://openalex.org/W2057139407","https://openalex.org/W2063575064","https://openalex.org/W2065338701","https://openalex.org/W2066205899","https://openalex.org/W2068050569","https://openalex.org/W2070730931","https://openalex.org/W2073869665","https://openalex.org/W2073884591","https://openalex.org/W2075865171","https://openalex.org/W2082526460","https://openalex.org/W2084867288","https://openalex.org/W2089155556","https://openalex.org/W2090105295","https://openalex.org/W2095412415","https://openalex.org/W2097863979","https://openalex.org/W2101673712","https://openalex.org/W2102449174","https://openalex.org/W2105156994","https://openalex.org/W2105390941","https://openalex.org/W2106955414","https://openalex.org/W2108615682","https://openalex.org/W2118561606","https://openalex.org/W2119692843","https://openalex.org/W2126358907","https://openalex.org/W2138329421","https://openalex.org/W2138618968","https://openalex.org/W2141240574","https://openalex.org/W2150322923","https://openalex.org/W2152942530","https://openalex.org/W2156694810","https://openalex.org/W2157923000","https://openalex.org/W2161825692","https://openalex.org/W2162750459","https://openalex.org/W2163051842","https://openalex.org/W2164841185","https://openalex.org/W2219584703","https://openalex.org/W2273495465","https://openalex.org/W2299956717","https://openalex.org/W2323261838","https://openalex.org/W2323559471","https://openalex.org/W2398075684","https://openalex.org/W2402506318","https://openalex.org/W2427645657","https://openalex.org/W2514160805","https://openalex.org/W2520907200","https://openalex.org/W2534069516","https://openalex.org/W2594036641","https://openalex.org/W2597235951","https://openalex.org/W2613428961","https://openalex.org/W2624697958","https://openalex.org/W2727828415","https://openalex.org/W2734327577","https://openalex.org/W2745482862","https://openalex.org/W2769418059","https://openalex.org/W2770358284","https://openalex.org/W2770477260","https://openalex.org/W2771641984","https://openalex.org/W2772216056","https://openalex.org/W2774011186","https://openalex.org/W2781527253","https://openalex.org/W2781749016","https://openalex.org/W2782706091","https://openalex.org/W2792200797","https://openalex.org/W2795670954","https://openalex.org/W2800978623","https://openalex.org/W2806310500","https://openalex.org/W2806417712","https://openalex.org/W2883359450","https://openalex.org/W2885803994","https://openalex.org/W2892287395","https://openalex.org/W2896681451","https://openalex.org/W2899522607","https://openalex.org/W2911882656","https://openalex.org/W2942027993","https://openalex.org/W2943106036","https://openalex.org/W2972122629","https://openalex.org/W2975915853","https://openalex.org/W2979375179","https://openalex.org/W2981858866","https://openalex.org/W2982255043","https://openalex.org/W3010114444","https://openalex.org/W3013170934","https://openalex.org/W3017154096","https://openalex.org/W3039977092","https://openalex.org/W3045080056","https://openalex.org/W3083784027","https://openalex.org/W3087854375","https://openalex.org/W3093557064","https://openalex.org/W3120568324","https://openalex.org/W3122173248","https://openalex.org/W3128646645","https://openalex.org/W3131917275","https://openalex.org/W3135501747","https://openalex.org/W3153418506","https://openalex.org/W3163221381","https://openalex.org/W3163566284","https://openalex.org/W3165315707","https://openalex.org/W3188161485","https://openalex.org/W3214314667","https://openalex.org/W4200231133","https://openalex.org/W4205455449","https://openalex.org/W4205824800","https://openalex.org/W4210471403","https://openalex.org/W4210534116","https://openalex.org/W4210853074","https://openalex.org/W4220781723","https://openalex.org/W4225565073","https://openalex.org/W4226016574","https://openalex.org/W4243734685","https://openalex.org/W4247718302","https://openalex.org/W4289636893","https://openalex.org/W4291675871","https://openalex.org/W4309835402","https://openalex.org/W4313334375","https://openalex.org/W4321459710","https://openalex.org/W4321497043","https://openalex.org/W4323670209","https://openalex.org/W4361225082","https://openalex.org/W4364381146","https://openalex.org/W4367337263","https://openalex.org/W4378979743","https://openalex.org/W4385226199","https://openalex.org/W4386006779","https://openalex.org/W4388654912"],"related_works":["https://openalex.org/W3134718177","https://openalex.org/W3083551364","https://openalex.org/W4394934376","https://openalex.org/W4412175163","https://openalex.org/W2981002433","https://openalex.org/W3083356949","https://openalex.org/W4238699323","https://openalex.org/W4401957333","https://openalex.org/W7166149039","https://openalex.org/W2996840406"],"abstract_inverted_index":{"Cancer":[0],"is":[1,25],"conventionally":[2],"treated":[3],"by":[4],"chemotherapy,":[5],"radiotherapy,":[6],"or":[7],"surgery.":[8],"The":[9],"urgent":[10],"need":[11],"to":[12,39,63],"look":[13],"for":[14],"alternative":[15],"therapeutic":[16],"strategies":[17],"reflects":[18],"many":[19],"loopholes.":[20],"Developing":[21],"a":[22,32,37,47],"drug,":[23],"however,":[24],"both":[26],"time-consuming":[27],"and":[28,68,83,86],"expensive.":[29],"Therefore,":[30],"repurposing":[31,85,93],"licensed":[33],"drug":[34,84,92],"along":[35],"with":[36],"means":[38],"take":[40],"care":[41],"of":[42,81],"the":[43,65,78],"limitations":[44],"can":[45],"become":[46],"very":[48],"sustainable":[49],"approach":[50],"in":[51,90],"cancer":[52,82],"therapy.":[53],"To":[54],"further":[55],"intensify":[56],"these":[57],"responses,":[58],"nanotechnology":[59],"would":[60],"be":[61],"useful":[62],"enhance":[64],"drug\u2019s":[66],"delivery":[67],"retention":[69],"while":[70],"reducing":[71],"toxicity.":[72],"In":[73],"this":[74],"review,":[75],"we":[76],"explore":[77],"complicated":[79],"association":[80],"summarize":[87],"recent":[88],"advances":[89],"nanomaterial-based":[91],"approaches.":[94]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3}],"updated_date":"2026-10-13T10:08:12.033832","created_date":"2024-02-04T00:00:00"}
