{"id":"https://openalex.org/W4391479905","doi":"https://doi.org/10.2147/dmso.s448476","title":"Exploring Promising Therapies for Non-Alcoholic Fatty Liver Disease: A ClinicalTrials.gov Analysis","display_name":"Exploring Promising Therapies for Non-Alcoholic Fatty Liver Disease: A ClinicalTrials.gov Analysis","publication_year":2024,"publication_date":"2024-02-01","ids":{"openalex":"https://openalex.org/W4391479905","doi":"https://doi.org/10.2147/dmso.s448476","pmid":"https://pubmed.ncbi.nlm.nih.gov/38327733","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10847589"},"language":"en","primary_location":{"id":"doi:10.2147/dmso.s448476","doi":"https://doi.org/10.2147/dmso.s448476","is_oa":true,"landing_page_url":"https://doi.org/10.2147/dmso.s448476","pdf_url":"https://www.dovepress.com/getfile.php?fileID=96481","source":{"id":"https://openalex.org/S176615914","display_name":"Diabetes Metabolic Syndrome and Obesity","issn_l":"1178-7007","issn":["1178-7007"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, Metabolic Syndrome and Obesity","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/getfile.php?fileID=96481","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048432808","display_name":"Omar E Hegazi","orcid":"https://orcid.org/0000-0001-9258-5920","observed_orcids":["https://orcid.org/0000-0001-9258-5920"]},"institutions":[{"id":"https://openalex.org/I182000528","display_name":"Ajman University","ror":"https://ror.org/01j1rma10","country_code":"AE","type":"education","lineage":["https://openalex.org/I182000528"]}],"countries":["AE"],"is_corresponding":false,"raw_author_name":"Omar Hegazi","raw_affiliation_strings":["Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates","Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman, United Arab Emirates"],"raw_orcid":"https://orcid.org/0000-0001-9258-5920","affiliations":[{"raw_affiliation_string":"Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates","institution_ids":["https://openalex.org/I182000528"]},{"raw_affiliation_string":"Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman, United Arab Emirates","institution_ids":["https://openalex.org/I182000528"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039855760","display_name":"Samer O Alalalmeh","orcid":"https://orcid.org/0000-0002-4762-9311","observed_orcids":["https://orcid.org/0000-0002-4762-9311"]},"institutions":[{"id":"https://openalex.org/I182000528","display_name":"Ajman University","ror":"https://ror.org/01j1rma10","country_code":"AE","type":"education","lineage":["https://openalex.org/I182000528"]}],"countries":["AE"],"is_corresponding":false,"raw_author_name":"Samer Alalalmeh","raw_affiliation_strings":["Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates","Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman, United Arab Emirates"],"raw_orcid":"https://orcid.org/0000-0002-4762-9311","affiliations":[{"raw_affiliation_string":"Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates","institution_ids":["https://openalex.org/I182000528"]},{"raw_affiliation_string":"Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman, United Arab Emirates","institution_ids":["https://openalex.org/I182000528"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087688051","display_name":"Moyad Jamal Shahwan","orcid":"https://orcid.org/0000-0001-8367-4841","observed_orcids":["https://orcid.org/0000-0001-8367-4841"]},"institutions":[{"id":"https://openalex.org/I182000528","display_name":"Ajman University","ror":"https://ror.org/01j1rma10","country_code":"AE","type":"education","lineage":["https://openalex.org/I182000528"]}],"countries":["AE"],"is_corresponding":false,"raw_author_name":"Moyad Shahwan","raw_affiliation_strings":["Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates","Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman, United Arab Emirates"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center of Medical and Bio-Allied Health Sciences Research, Ajman University, Ajman, United Arab Emirates","institution_ids":["https://openalex.org/I182000528"]},{"raw_affiliation_string":"Department of Clinical Sciences, College of Pharmacy and Health Sciences, Ajman University, Ajman, United Arab Emirates","institution_ids":["https://openalex.org/I182000528"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083200017","display_name":"Ammar Abdulrahman Jairoun","orcid":"https://orcid.org/0000-0002-4471-0878","observed_orcids":["https://orcid.org/0000-0002-4471-0878"]},"institutions":[{"id":"https://openalex.org/I1287366011","display_name":"Dubai Health Authority","ror":"https://ror.org/01dcrt245","country_code":"AE","type":"government","lineage":["https://openalex.org/I1287366011"]},{"id":"https://openalex.org/I139322472","display_name":"Universiti Sains Malaysia","ror":"https://ror.org/02rgb2k63","country_code":"MY","type":"education","lineage":["https://openalex.org/I139322472"]}],"countries":["AE","MY"],"is_corresponding":false,"raw_author_name":"Ammar Jairoun","raw_affiliation_strings":["Health and Safety Department, Dubai, United Arab Emirates","School of Pharmaceutical Sciences, Universiti Sains Malaysia, Pulau Pinang, Malaysia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Health and Safety Department, Dubai, United Arab Emirates","institution_ids":["https://openalex.org/I1287366011"]},{"raw_affiliation_string":"School of Pharmaceutical Sciences, Universiti Sains Malaysia, Pulau Pinang, Malaysia","institution_ids":["https://openalex.org/I139322472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035422281","display_name":"Mansour M. Alourfi","orcid":"https://orcid.org/0000-0002-8417-6155","observed_orcids":["https://orcid.org/0000-0002-8417-6155"]},"institutions":[{"id":"https://openalex.org/I4405275801","display_name":"East Jeddah Hospital","ror":"https://ror.org/04afsdm50","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210127754","https://openalex.org/I4405269311","https://openalex.org/I4405275801"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Mansour Alourfi","raw_affiliation_strings":["Department of gastroenterology, East Jeddah hospital, Jeddah, Saudi Arabia","Internal medicine Department, King Faisal Medical City for Southern Region, Abha, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of gastroenterology, East Jeddah hospital, Jeddah, Saudi Arabia","institution_ids":["https://openalex.org/I4405275801"]},{"raw_affiliation_string":"Internal medicine Department, King Faisal Medical City for Southern Region, Abha, Saudi Arabia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092900220","display_name":"Ghfran Bokhari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405275801","display_name":"East Jeddah Hospital","ror":"https://ror.org/04afsdm50","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210127754","https://openalex.org/I4405269311","https://openalex.org/I4405275801"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Ghfran Bokhari","raw_affiliation_strings":["Department of gastroenterology, East Jeddah hospital, Jeddah, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of gastroenterology, East Jeddah hospital, Jeddah, Saudi Arabia","institution_ids":["https://openalex.org/I4405275801"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010198629","display_name":"Abdullah Alkhattabi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405275801","display_name":"East Jeddah Hospital","ror":"https://ror.org/04afsdm50","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210127754","https://openalex.org/I4405269311","https://openalex.org/I4405275801"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Abdullah Alkhattabi","raw_affiliation_strings":["Department of gastroenterology, East Jeddah hospital, Jeddah, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of gastroenterology, East Jeddah hospital, Jeddah, Saudi Arabia","institution_ids":["https://openalex.org/I4405275801"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065318242","display_name":"Saeed Alsharif","orcid":"https://orcid.org/0000-0002-3105-6600","observed_orcids":["https://orcid.org/0000-0002-3105-6600"]},"institutions":[{"id":"https://openalex.org/I4399598369","display_name":"Armed Forces Hospital Southern Region","ror":"https://ror.org/05r1hax23","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4399598369"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Saeed Alsharif","raw_affiliation_strings":["Gastroenterology Department, Armed force Hospital of southern region, Khamis Mushait, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology Department, Armed force Hospital of southern region, Khamis Mushait, Saudi Arabia","institution_ids":["https://openalex.org/I4399598369"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034093457","display_name":"Mohannad Abdulrahman Aljehani","orcid":"https://orcid.org/0000-0001-5757-3182","observed_orcids":["https://orcid.org/0000-0001-5757-3182"]},"institutions":[{"id":"https://openalex.org/I2800965796","display_name":"King Faisal Specialist Hospital & Research Centre","ror":"https://ror.org/05n0wgt02","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I2800965796"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Mohannad Aljehani","raw_affiliation_strings":["Division of Gastroenterology, Department of Medicine, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gastroenterology, Department of Medicine, King Faisal Specialist Hospital and Research Centre, Jeddah, Saudi Arabia","institution_ids":["https://openalex.org/I2800965796"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081917856","display_name":"Abdulmalik Alsabban","orcid":"https://orcid.org/0009-0006-8056-4181","observed_orcids":["https://orcid.org/0009-0006-8056-4181"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Abdulmalik Alsabban","raw_affiliation_strings":["Gastroenterology Section, Department of Medicine, King Abdulaziz Medical City, Jeddah, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology Section, Department of Medicine, King Abdulaziz Medical City, Jeddah, Saudi Arabia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093849190","display_name":"Mohammad Almtrafi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mohammad Almtrafi","raw_affiliation_strings":["Gastroenterology Section, Department of Medicine, King Abdulaziz Medical City, Jeddah, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology Section, Department of Medicine, King Abdulaziz Medical City, Jeddah, Saudi Arabia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093462777","display_name":"Ysear Zakri","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ysear Zakri","raw_affiliation_strings":["Gastroenterology Section, Department of Medicine, King Abdulaziz Medical City, Jeddah, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology Section, Department of Medicine, King Abdulaziz Medical City, Jeddah, Saudi Arabia","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033527805","display_name":"Abdullah AlMahmoud","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210149826","display_name":"King Fahad Hospital Jeddah","ror":"https://ror.org/04ws1n245","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210149826"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Abdullah AlMahmoud","raw_affiliation_strings":["Gastroenterology Section, Internal Medicine Department, King Fahad Hospital, Jeddah, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology Section, Internal Medicine Department, King Fahad Hospital, Jeddah, Saudi Arabia","institution_ids":["https://openalex.org/I4210149826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101972687","display_name":"Khalid A Alghamdi","orcid":"https://orcid.org/0009-0002-6518-750X","observed_orcids":["https://orcid.org/0009-0002-6518-750X","https://orcid.org/0000-0003-4009-8789"]},"institutions":[{"id":"https://openalex.org/I4210149826","display_name":"King Fahad Hospital Jeddah","ror":"https://ror.org/04ws1n245","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I4210149826"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Khalid Alghamdi","raw_affiliation_strings":["Gastroenterology Section, Internal Medicine Department, King Fahad Hospital, Jeddah, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gastroenterology Section, Internal Medicine Department, King Fahad Hospital, Jeddah, Saudi Arabia","institution_ids":["https://openalex.org/I4210149826"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006334930","display_name":"Ahmed M. Ashour","orcid":"https://orcid.org/0000-0002-2118-0499","observed_orcids":["https://orcid.org/0000-0002-2118-0499"]},"institutions":[{"id":"https://openalex.org/I199693650","display_name":"Umm al-Qura University","ror":"https://ror.org/01xjqrm90","country_code":"SA","type":"education","lineage":["https://openalex.org/I199693650"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Ahmed Ashour","raw_affiliation_strings":["Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia"],"raw_orcid":"https://orcid.org/0000-0002-2118-0499","affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia","institution_ids":["https://openalex.org/I199693650"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050007007","display_name":"Nasser M. Alorfi","orcid":"https://orcid.org/0000-0002-0636-7685","observed_orcids":["https://orcid.org/0000-0002-0636-7685"]},"institutions":[{"id":"https://openalex.org/I199693650","display_name":"Umm al-Qura University","ror":"https://ror.org/01xjqrm90","country_code":"SA","type":"education","lineage":["https://openalex.org/I199693650"]}],"countries":["SA"],"is_corresponding":true,"raw_author_name":"Nasser Alorfi","raw_affiliation_strings":["Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia"],"raw_orcid":"https://orcid.org/0000-0002-0636-7685","affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia","institution_ids":["https://openalex.org/I199693650"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5050007007"],"corresponding_institution_ids":["https://openalex.org/I199693650"],"apc_list":{"value":2836,"currency":"USD","value_usd":2836},"apc_paid":{"value":2836,"currency":"USD","value_usd":2836},"fwci":0.3788,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.41443976,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"Volume 17","issue":null,"first_page":"545","last_page":"561"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10401","display_name":"Diabetes Treatment and Management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10073","display_name":"Hepatocellular Carcinoma Treatment and Prognosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/non-alcoholic-fatty-liver-disease","display_name":"non-alcoholic fatty liver disease","score":1.0},{"id":"https://openalex.org/keywords/drug-development","display_name":"drug development","score":0.5720000267028809},{"id":"https://openalex.org/keywords/metformin","display_name":"metformin","score":0.8529999852180481},{"id":"https://openalex.org/keywords/exenatide","display_name":"exenatide","score":0.996999979019165},{"id":"https://openalex.org/keywords/pioglitazone","display_name":"pioglitazone","score":1.0},{"id":"https://openalex.org/keywords/clinicaltrials-gov","display_name":"ClinicalTrials.gov","score":0.7319999933242798},{"id":"https://openalex.org/keywords/clinical-trial-registries","display_name":"clinical trial registries","score":0.34200000762939453},{"id":"https://openalex.org/keywords/antidiabetic-drugs","display_name":"antidiabetic drugs","score":0.550000011920929}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8470519781112671},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.7793041467666626},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.674548327922821},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6735104918479919},{"id":"https://openalex.org/C2778384471","wikidata":"https://www.wikidata.org/wiki/Q417765","display_name":"Pioglitazone","level":4,"score":0.6358171105384827},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5280129313468933},{"id":"https://openalex.org/C2780323712","wikidata":"https://www.wikidata.org/wiki/Q19484","display_name":"Metformin","level":3,"score":0.521388828754425},{"id":"https://openalex.org/C41260117","wikidata":"https://www.wikidata.org/wiki/Q668064","display_name":"Hepatology","level":2,"score":0.5052703022956848},{"id":"https://openalex.org/C2780533449","wikidata":"https://www.wikidata.org/wiki/Q417762","display_name":"Exenatide","level":4,"score":0.4271857440471649},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3775673508644104},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.16020020842552185},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.11333966255187988},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.09203594923019409},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.2147/dmso.s448476","doi":"https://doi.org/10.2147/dmso.s448476","is_oa":true,"landing_page_url":"https://doi.org/10.2147/dmso.s448476","pdf_url":"https://www.dovepress.com/getfile.php?fileID=96481","source":{"id":"https://openalex.org/S176615914","display_name":"Diabetes Metabolic Syndrome and Obesity","issn_l":"1178-7007","issn":["1178-7007"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, Metabolic Syndrome and Obesity","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10847589","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10847589","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10847589/pdf/dmso-17-545.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes Metab Syndr Obes","raw_type":"Text"},{"id":"pmid:38327733","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38327733","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, metabolic syndrome and obesity : targets and therapy","raw_type":"Journal Article"},{"id":"pmh:oai:dovepress.com/90187","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/exploring-promising-therapies-for-non-alcoholic-fatty-liver-disease-a--peer-reviewed-fulltext-article-DMSO","pdf_url":"https://www.dovepress.com/article/download/90187","source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Review"},{"id":"pmh:oai:doaj.org/article:dc5ad32e2c0b469ebdb1afed05b6dccc","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/dc5ad32e2c0b469ebdb1afed05b6dccc","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Diabetes, Metabolic Syndrome and Obesity, Vol Volume 17, Pp 545-561 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.2147/dmso.s448476","doi":"https://doi.org/10.2147/dmso.s448476","is_oa":true,"landing_page_url":"https://doi.org/10.2147/dmso.s448476","pdf_url":"https://www.dovepress.com/getfile.php?fileID=96481","source":{"id":"https://openalex.org/S176615914","display_name":"Diabetes Metabolic Syndrome and Obesity","issn_l":"1178-7007","issn":["1178-7007"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Diabetes, Metabolic Syndrome and Obesity","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Systematic Review","id":"https://openalex.org/study-designs/systematic-review"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4391479905.pdf","grobid_xml":"https://content.openalex.org/works/W4391479905.grobid-xml"},"referenced_works_count":105,"referenced_works":["https://openalex.org/W98196760","https://openalex.org/W129435905","https://openalex.org/W303691883","https://openalex.org/W1545747221","https://openalex.org/W1967027009","https://openalex.org/W1976060830","https://openalex.org/W1991412148","https://openalex.org/W1996233118","https://openalex.org/W2008493682","https://openalex.org/W2009480581","https://openalex.org/W2020080482","https://openalex.org/W2022394079","https://openalex.org/W2029880863","https://openalex.org/W2041572943","https://openalex.org/W2042527557","https://openalex.org/W2057445384","https://openalex.org/W2060476230","https://openalex.org/W2080042784","https://openalex.org/W2101302239","https://openalex.org/W2104147351","https://openalex.org/W2105634155","https://openalex.org/W2110393515","https://openalex.org/W2112076043","https://openalex.org/W2122983268","https://openalex.org/W2133322617","https://openalex.org/W2140898295","https://openalex.org/W2144275312","https://openalex.org/W2154194502","https://openalex.org/W2157653770","https://openalex.org/W2160832007","https://openalex.org/W2273304042","https://openalex.org/W2288138432","https://openalex.org/W2302367542","https://openalex.org/W2413507055","https://openalex.org/W2417430601","https://openalex.org/W2418775084","https://openalex.org/W2498598018","https://openalex.org/W2547815051","https://openalex.org/W2616276679","https://openalex.org/W2629223022","https://openalex.org/W2744078963","https://openalex.org/W2761135733","https://openalex.org/W2783806692","https://openalex.org/W2787406891","https://openalex.org/W2807255399","https://openalex.org/W2807282451","https://openalex.org/W2887902401","https://openalex.org/W2912548489","https://openalex.org/W2916118611","https://openalex.org/W2922399282","https://openalex.org/W2939474006","https://openalex.org/W2982659269","https://openalex.org/W2982683311","https://openalex.org/W2990201342","https://openalex.org/W3006875859","https://openalex.org/W3020979243","https://openalex.org/W3034453691","https://openalex.org/W3037894148","https://openalex.org/W3044739183","https://openalex.org/W3080211465","https://openalex.org/W3092443860","https://openalex.org/W3096075211","https://openalex.org/W3109302943","https://openalex.org/W3120113718","https://openalex.org/W3122988712","https://openalex.org/W3126542097","https://openalex.org/W3127004353","https://openalex.org/W3134320092","https://openalex.org/W3136724397","https://openalex.org/W3141754751","https://openalex.org/W3144197674","https://openalex.org/W3159156911","https://openalex.org/W3163145714","https://openalex.org/W3175909657","https://openalex.org/W3196309856","https://openalex.org/W3213187811","https://openalex.org/W3214293028","https://openalex.org/W4200273929","https://openalex.org/W4207073091","https://openalex.org/W4213380151","https://openalex.org/W4220832833","https://openalex.org/W4220913390","https://openalex.org/W4232605589","https://openalex.org/W4251153431","https://openalex.org/W4255277723","https://openalex.org/W4281711734","https://openalex.org/W4282941901","https://openalex.org/W4283165920","https://openalex.org/W4289175477","https://openalex.org/W4310995254","https://openalex.org/W4312070346","https://openalex.org/W4316664733","https://openalex.org/W4321486907","https://openalex.org/W4361297693","https://openalex.org/W4362580957","https://openalex.org/W4364377488","https://openalex.org/W4377290373","https://openalex.org/W4379988136","https://openalex.org/W4380629916","https://openalex.org/W4382317706","https://openalex.org/W4385430823","https://openalex.org/W4385451117","https://openalex.org/W4387219421","https://openalex.org/W4387309174","https://openalex.org/W4387403771"],"related_works":["https://openalex.org/W4387654844","https://openalex.org/W4385451117","https://openalex.org/W3208161049","https://openalex.org/W4312187211","https://openalex.org/W7135191969","https://openalex.org/W2166525409","https://openalex.org/W4386042266","https://openalex.org/W2994519987","https://openalex.org/W3043273029","https://openalex.org/W4210259668"],"abstract_inverted_index":{"Background:":[0],"Non-alcoholic":[1],"fatty":[2],"liver":[3],"disease":[4,9],"(NAFLD)":[5],"is":[6],"a":[7,37],"common":[8,123],"and":[10,32,65,118,132],"has":[11],"been":[12],"increasing":[13],"in":[14,36,62,83,115],"recent":[15],"years.":[16],"To":[17],"date,":[18],"no":[19],"FDA-approved":[20],"drug":[21],"specifically":[22],"targets":[23],"NAFLD.":[24,84],"Methods:":[25],"The":[26,74,85,104,110,121],"terms":[27],"\"Non-alcoholic":[28],"Fatty":[29],"Liver":[30],"Disease\"":[31],"\"NAFLD\"":[33],"were":[34,100,114],"used":[35,139],"search":[38,86],"of":[39,97],"ClinicalTrials.gov":[40,75],"on":[41],"August":[42],"24,":[43],"2023.":[44],"Two":[45],"evaluators":[46],"independently":[47],"examined":[48],"the":[49,93],"trials":[50,80],"using":[51],"predetermined":[52],"eligibility":[53],"criteria.":[54,95],"Studies":[55],"had":[56],"to":[57,67,140],"be":[58,68],"interventional,":[59],"NAFLD":[60,142],"focused,":[61],"Phase":[63],"IV,":[64],"completed":[66],"eligible":[69],"for":[70,79,102,135],"this":[71],"review.":[72],"Results:":[73],"database":[76],"was":[77,108,125],"searched":[78],"examining":[81],"pharmacotherapeutics":[82],"revealed":[87],"1364":[88],"trials,":[89],"with":[90,128],"31":[91],"meeting":[92],"inclusion":[94],"Out":[96],"these,":[98],"19":[99],"finalized":[101],"evaluation.":[103],"dominant":[105],"intervention":[106,124],"model":[107],"Parallel.":[109],"most":[111,122],"prevalent":[112],"studies":[113],"Korea":[116],"(26.3%)":[117],"China":[119],"(21.1%).":[120],"metformin":[126],"(12.1%),":[127],"others":[129],"like":[130],"Exenatide":[131],"Pioglitazone":[133],"accounting":[134],"9.1%.":[136],"Conclusion:":[137],"Therapeutics":[138],"manage":[141],"are":[143,153],"limited.":[144],"However,":[145],"various":[146],"medications":[147],"offer":[148],"potential":[149],"benefits.":[150],"Further":[151],"investigations":[152],"definitely":[154],"warranted.":[155]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2024-02-03T00:00:00"}