{"id":"https://openalex.org/W4391474569","doi":"https://doi.org/10.1016/j.jacig.2024.100225","title":"Longitudinal patterns of intermittent oral corticosteroid therapy for asthma in the United Kingdom","display_name":"Longitudinal patterns of intermittent oral corticosteroid therapy for asthma in the United Kingdom","publication_year":2024,"publication_date":"2024-02-02","ids":{"openalex":"https://openalex.org/W4391474569","doi":"https://doi.org/10.1016/j.jacig.2024.100225","pmid":"https://pubmed.ncbi.nlm.nih.gov/38524787","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10959664"},"language":"en","primary_location":{"id":"doi:10.1016/j.jacig.2024.100225","doi":"https://doi.org/10.1016/j.jacig.2024.100225","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacig.2024.100225","pdf_url":"http://www.jaci-global.org/article/S2772829324000213/pdf","source":{"id":"https://openalex.org/S4210197719","display_name":"Journal of Allergy and Clinical Immunology Global","issn_l":"2772-8293","issn":["2772-8293"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology: Global","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.jaci-global.org/article/S2772829324000213/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024799300","display_name":"Trung Nam Tran","orcid":"https://orcid.org/0000-0001-8003-7601","observed_orcids":["https://orcid.org/0000-0001-8003-7601"]},"institutions":[{"id":"https://openalex.org/I4210150756","display_name":"AstraZeneca (United States)","ror":"https://ror.org/043cec594","country_code":"US","type":"company","lineage":["https://openalex.org/I105036370","https://openalex.org/I4210150756"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Trung N. Tran","raw_affiliation_strings":["BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Md"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Md","institution_ids":["https://openalex.org/I4210150756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076694866","display_name":"Heath Heatley","orcid":"https://orcid.org/0009-0006-8500-1812","observed_orcids":["https://orcid.org/0009-0006-8500-1812"]},"institutions":[{"id":"https://openalex.org/I4210118135","display_name":"Observational & Pragmatic Research Institute","ror":"https://ror.org/02gq3ch54","country_code":"SG","type":"other","lineage":["https://openalex.org/I4210118135"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Heath Heatley","raw_affiliation_strings":["Observational and Pragmatic Research Institute, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Observational and Pragmatic Research Institute, Singapore","institution_ids":["https://openalex.org/I4210118135"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064031388","display_name":"Jennifer Voigt Rowell","orcid":"https://orcid.org/0000-0003-1953-9770","observed_orcids":["https://orcid.org/0000-0003-1953-9770"]},"institutions":[{"id":"https://openalex.org/I105036370","display_name":"AstraZeneca (United Kingdom)","ror":"https://ror.org/04r9x1a08","country_code":"GB","type":"company","lineage":["https://openalex.org/I105036370"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jennifer Rowell","raw_affiliation_strings":["AstraZeneca, Cambridge, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AstraZeneca, Cambridge, United Kingdom","institution_ids":["https://openalex.org/I105036370"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068206765","display_name":"Jeffrey Shi Kai Chan","orcid":"https://orcid.org/0000-0003-0231-2393","observed_orcids":["https://orcid.org/0000-0003-0231-2393"]},"institutions":[{"id":"https://openalex.org/I4210150756","display_name":"AstraZeneca (United States)","ror":"https://ror.org/043cec594","country_code":"US","type":"company","lineage":["https://openalex.org/I105036370","https://openalex.org/I4210150756"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey Shi Kai Chan","raw_affiliation_strings":["BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Md"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Md","institution_ids":["https://openalex.org/I4210150756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038824744","display_name":"ARNAUD AB BOURDIN","orcid":"https://orcid.org/0000-0002-4645-5209","observed_orcids":["https://orcid.org/0000-0002-4645-5209"]},"institutions":[{"id":"https://openalex.org/I19894307","display_name":"Universit\u00e9 de Montpellier","ror":"https://ror.org/051escj72","country_code":"FR","type":"education","lineage":["https://openalex.org/I19894307"]},{"id":"https://openalex.org/I4210086516","display_name":"Physiologie et M\u00e9decine Exp\u00e9rimentale du Coeur et des Muscles","ror":"https://ror.org/003sscq03","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I19894307","https://openalex.org/I4210086516","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Arnaud Bourdin","raw_affiliation_strings":["Department of Respiratory Diseases, PhyMedExp, University of Montpellier, Montpellier, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Diseases, PhyMedExp, University of Montpellier, Montpellier, France","institution_ids":["https://openalex.org/I19894307","https://openalex.org/I4210086516"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055317344","display_name":"Jatin Chapaneri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I105036370","display_name":"AstraZeneca (United Kingdom)","ror":"https://ror.org/04r9x1a08","country_code":"GB","type":"company","lineage":["https://openalex.org/I105036370"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jatin Chapaneri","raw_affiliation_strings":["AstraZeneca, Cambridge, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AstraZeneca, Cambridge, United Kingdom","institution_ids":["https://openalex.org/I105036370"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017997492","display_name":"Benjamin Emmanuel","orcid":"https://orcid.org/0000-0003-1769-9826","observed_orcids":["https://orcid.org/0000-0003-1769-9826"]},"institutions":[{"id":"https://openalex.org/I4210150756","display_name":"AstraZeneca (United States)","ror":"https://ror.org/043cec594","country_code":"US","type":"company","lineage":["https://openalex.org/I105036370","https://openalex.org/I4210150756"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin Emmanuel","raw_affiliation_strings":["BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Md"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BioPharmaceuticals Medical, AstraZeneca, Gaithersburg, Md","institution_ids":["https://openalex.org/I4210150756"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060904655","display_name":"Danny Gibson","orcid":"https://orcid.org/0009-0004-5979-1756","observed_orcids":["https://orcid.org/0009-0004-5979-1756"]},"institutions":[{"id":"https://openalex.org/I105036370","display_name":"AstraZeneca (United Kingdom)","ror":"https://ror.org/04r9x1a08","country_code":"GB","type":"company","lineage":["https://openalex.org/I105036370"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Danny Gibson","raw_affiliation_strings":["AstraZeneca, Cambridge, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AstraZeneca, Cambridge, United Kingdom","institution_ids":["https://openalex.org/I105036370"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073147866","display_name":"David J. Jackson","orcid":"https://orcid.org/0000-0002-2299-868X","observed_orcids":["https://orcid.org/0000-0002-2299-868X"]},"institutions":[{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"David J. Jackson","raw_affiliation_strings":["Guy's and St Thomas' NHS Trust and School of Immunology & Microbial Sciences, King's College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Guy's and St Thomas' NHS Trust and School of Immunology & Microbial Sciences, King's College, London, United Kingdom","institution_ids":["https://openalex.org/I183935753"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022389916","display_name":"Andrew N Menzies-Gow","orcid":"https://orcid.org/0000-0001-9707-4986","observed_orcids":["https://orcid.org/0000-0001-9707-4986"]},"institutions":[{"id":"https://openalex.org/I105036370","display_name":"AstraZeneca (United Kingdom)","ror":"https://ror.org/04r9x1a08","country_code":"GB","type":"company","lineage":["https://openalex.org/I105036370"]},{"id":"https://openalex.org/I183935753","display_name":"King's College London","ror":"https://ror.org/0220mzb33","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I183935753"]},{"id":"https://openalex.org/I2802782613","display_name":"Harefield Hospital","ror":"https://ror.org/04fwa4t58","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2800036501","https://openalex.org/I2802782613"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Andrew N. Menzies-Gow","raw_affiliation_strings":["Respiratory and Immunology, BioPharmaceuticals Medical, AstraZeneca, Cambridge, United Kingdom","UK Severe Asthma Network and National Registry, Royal Brompton & Harefield Hospitals and School of Immunology & Microbial Sciences, King's College, London, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Respiratory and Immunology, BioPharmaceuticals Medical, AstraZeneca, Cambridge, United Kingdom","institution_ids":["https://openalex.org/I105036370"]},{"raw_affiliation_string":"UK Severe Asthma Network and National Registry, Royal Brompton & Harefield Hospitals and School of Immunology & Microbial Sciences, King's College, London, United Kingdom","institution_ids":["https://openalex.org/I183935753","https://openalex.org/I2802782613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020325951","display_name":"Ruth Murray","orcid":"https://orcid.org/0000-0002-2821-978X","observed_orcids":["https://orcid.org/0000-0002-2821-978X"]},"institutions":[{"id":"https://openalex.org/I4405269660","display_name":"Optimum Patient Care","ror":"https://ror.org/04v9bt015","country_code":"GB","type":"nonprofit","lineage":["https://openalex.org/I4405269660"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ruth Murray","raw_affiliation_strings":["Optimum Patient Care, Cambridge, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Optimum Patient Care, Cambridge, United Kingdom","institution_ids":["https://openalex.org/I4405269660"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012781295","display_name":"Derek Skinner","orcid":"https://orcid.org/0000-0002-7112-9317","observed_orcids":["https://orcid.org/0000-0002-7112-9317"]},"institutions":[{"id":"https://openalex.org/I4210118135","display_name":"Observational & Pragmatic Research Institute","ror":"https://ror.org/02gq3ch54","country_code":"SG","type":"other","lineage":["https://openalex.org/I4210118135"]}],"countries":["SG"],"is_corresponding":false,"raw_author_name":"Derek Skinner","raw_affiliation_strings":["Observational and Pragmatic Research Institute, Singapore"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Observational and Pragmatic Research Institute, Singapore","institution_ids":["https://openalex.org/I4210118135"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5052175038","display_name":"David Brendan Price","orcid":"https://orcid.org/0000-0002-9728-9992","observed_orcids":["https://orcid.org/0000-0002-9728-9992","https://orcid.org/0000-0002-1195-039X"]},"institutions":[{"id":"https://openalex.org/I195460627","display_name":"University of Aberdeen","ror":"https://ror.org/016476m91","country_code":"GB","type":"education","lineage":["https://openalex.org/I195460627"]},{"id":"https://openalex.org/I4210118135","display_name":"Observational & Pragmatic Research Institute","ror":"https://ror.org/02gq3ch54","country_code":"SG","type":"other","lineage":["https://openalex.org/I4210118135"]}],"countries":["GB","SG"],"is_corresponding":true,"raw_author_name":"David B. Price","raw_affiliation_strings":["Centre of Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom","Observational and Pragmatic Research Institute, Singapore"],"raw_orcid":"https://orcid.org/0000-0002-9728-9992","affiliations":[{"raw_affiliation_string":"Centre of Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, United Kingdom","institution_ids":["https://openalex.org/I195460627"]},{"raw_affiliation_string":"Observational and Pragmatic Research Institute, Singapore","institution_ids":["https://openalex.org/I4210118135"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5052175038"],"corresponding_institution_ids":["https://openalex.org/I195460627","https://openalex.org/I4210118135"],"apc_list":{"value":2000,"currency":"USD","value_usd":2000},"apc_paid":{"value":2000,"currency":"USD","value_usd":2000},"fwci":2.0684,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.85889986,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"3","issue":"2","first_page":"100225","last_page":"100225"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12421","display_name":"Adrenal Hormones and Disorders","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/asthma","display_name":"asthma","score":0.703000009059906},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.4959999918937683},{"id":"https://openalex.org/keywords/peak-expiratory-flow","display_name":"peak expiratory flow","score":0.8769999742507935},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.5770000219345093},{"id":"https://openalex.org/keywords/smoking","display_name":"smoking","score":0.9769999980926514},{"id":"https://openalex.org/keywords/sex-differences","display_name":"sex differences","score":0.6930000185966492},{"id":"https://openalex.org/keywords/age","display_name":"age","score":0.4699999988079071},{"id":"https://openalex.org/keywords/primary-care-prescribing","display_name":"primary care prescribing","score":0.6850000023841858}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7653535008430481},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.7377719283103943},{"id":"https://openalex.org/C2776804153","wikidata":"https://www.wikidata.org/wiki/Q210420","display_name":"Corticosteroid","level":2,"score":0.7279410362243652},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.6455108523368835},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.6432859301567078},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.48769912123680115},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.36129432916641235},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3261232376098633},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.27468395233154297},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.11259439587593079}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.1016/j.jacig.2024.100225","doi":"https://doi.org/10.1016/j.jacig.2024.100225","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacig.2024.100225","pdf_url":"http://www.jaci-global.org/article/S2772829324000213/pdf","source":{"id":"https://openalex.org/S4210197719","display_name":"Journal of Allergy and Clinical Immunology Global","issn_l":"2772-8293","issn":["2772-8293"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology: Global","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10959664","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10959664","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10959664/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Allergy Clin Immunol Glob","raw_type":"Text"},{"id":"pmid:38524787","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38524787","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The journal of allergy and clinical immunology. Global","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-04533740v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-04533740","pdf_url":"https://hal.science/hal-04533740v1/document","source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Allergy and Clinical Immunology: Global, 2024, 3 (2), pp.100225. ⟨10.1016/j.jacig.2024.100225⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:aura.abdn.ac.uk:2164/23318","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/2164/23318","pdf_url":null,"source":{"id":"https://openalex.org/S4306400966","display_name":"Aberdeen University Research Archive (Aberdeen University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I195460627","host_organization_name":"University of Aberdeen","host_organization_lineage":["https://openalex.org/I195460627"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal article"},{"id":"pmh:oai:doaj.org/article:a6b326d0480546b0b054b4170e457828","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/a6b326d0480546b0b054b4170e457828","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Allergy and Clinical Immunology: Global, Vol 3, Iss 2, Pp 100225- (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.jacig.2024.100225","doi":"https://doi.org/10.1016/j.jacig.2024.100225","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jacig.2024.100225","pdf_url":"http://www.jaci-global.org/article/S2772829324000213/pdf","source":{"id":"https://openalex.org/S4210197719","display_name":"Journal of Allergy and Clinical Immunology Global","issn_l":"2772-8293","issn":["2772-8293"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","jufo-1","ki-jl-1","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology: Global","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320307105","display_name":"Amgen","ror":"https://ror.org/03g03ge92"},{"id":"https://openalex.org/F4320307765","display_name":"Pfizer","ror":"https://ror.org/01xdqrp08"},{"id":"https://openalex.org/F4320307770","display_name":"AstraZeneca","ror":"https://ror.org/04r9x1a08"},{"id":"https://openalex.org/F4320307773","display_name":"GlaxoSmithKline","ror":"https://ror.org/01xsqw823"},{"id":"https://openalex.org/F4320307781","display_name":"Sanofi","ror":"https://ror.org/027vj4x92"},{"id":"https://openalex.org/F4320308970","display_name":"Teva Pharmaceutical Industries","ror":"https://ror.org/01wfv3m53"},{"id":"https://openalex.org/F4320311600","display_name":"Regeneron Pharmaceuticals","ror":"https://ror.org/02f51rf24"},{"id":"https://openalex.org/F4320314792","display_name":"Respiratory Effectiveness Group","ror":"https://ror.org/01m56pn68"},{"id":"https://openalex.org/F4320316473","display_name":"Mylan","ror":"https://ror.org/04nsw4151"},{"id":"https://openalex.org/F4320330279","display_name":"AKL Research and Development","ror":"https://ror.org/04mcppw82"},{"id":"https://openalex.org/F4320333587","display_name":"Sanofi Genzyme","ror":null},{"id":"https://openalex.org/F4320334783","display_name":"Efficacy and Mechanism Evaluation Programme","ror":"https://ror.org/0187kwz08"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4391474569.pdf","grobid_xml":"https://content.openalex.org/works/W4391474569.grobid-xml"},"referenced_works_count":8,"referenced_works":["https://openalex.org/W2974441349","https://openalex.org/W2991287546","https://openalex.org/W3012084339","https://openalex.org/W3015029848","https://openalex.org/W3201814625","https://openalex.org/W4283805826","https://openalex.org/W4313250863","https://openalex.org/W4323075737"],"related_works":["https://openalex.org/W4313250863","https://openalex.org/W3215958872","https://openalex.org/W4399853014","https://openalex.org/W4323075737","https://openalex.org/W4280511699","https://openalex.org/W3148061507","https://openalex.org/W4408803488","https://openalex.org/W3036836496","https://openalex.org/W2990555236","https://openalex.org/W3012084339"],"abstract_inverted_index":{"Background:":[0],"Increasing":[1],"frequency":[2],"of":[3,16,29,106,118,158,184,217,228],"intermittent":[4,30,123,141,232],"oral":[5],"corticosteroid":[6],"(OCS)":[7],"prescription":[8,32,49,79,113,125,152,166,179],"and":[9,27,38,66,115,194,207,235],"cumulative":[10],"OCS":[11,31,78,112,124,142,151,233],"exposure":[12],"increase":[13],"the":[14,25,69,116,168,182],"risk":[15,40,173,216,227],"OCS-related":[17],"adverse":[18],"outcomes.":[19],"Objective:":[20],"We":[21,108],"sought":[22],"to":[23,46,164,230],"describe":[24],"evolution":[26],"trajectory":[28],"patterns":[33,80],"in":[34,62,68,102],"patients":[35,57,139,162],"with":[36,44,58,131,140,213,239],"asthma":[37,60],"investigate":[39],"factors":[41,174],"independently":[42],"associated":[43,212],"transitioning":[45,119,229],"a":[47,99,121,132,149,176,187,214],"frequent":[48,100,122,150,165,178,231],"pattern.":[50],"Methods:":[51],"This":[52],"historical":[53],"cohort":[54],"study":[55],"included":[56,67],"active":[59,208],"managed":[61],"UK":[63],"primary":[64],"care":[65],"Optimum":[70],"Patient":[71],"Care":[72],"Research":[73],"Database":[74],"(OPCRD;":[75],"opcrd.co.uk).":[76],"Intermittent":[77],"were":[81,93,175,210],"categorized":[82],"as":[83],"sporadic,":[84],"infrequent,":[85],"moderately":[86],"frequent,":[87],"or":[88],"frequent.":[89],"Prescription":[90],"pattern":[91,114,126,153,180],"sequences":[92],"described":[94],"for":[95,198],"those":[96,224],"who":[97],"had":[98,148],"sequence":[101],"their":[103],"final":[104],"year":[105],"prescribing.":[107],"examined":[109],"associations":[110],"between":[111],"hazard":[117],"into":[120],"using":[127],"multivariable":[128],"Cox":[129],"regression":[130],"10-year":[133],"look-back":[134,185],"period.":[135],"Results:":[136],"Of":[137],"105,229":[138],"prescriptions,":[143],"57.1%":[144],"(n":[145],"=":[146],"60,083)":[147],"at":[154,181,226],"some":[155],"point.":[156],"Irrespective":[157],"baseline":[159],"pattern,":[160],"most":[161,225],"transitioned":[163],"during":[167],"look":[169],"back.":[170],"The":[171],"strongest":[172],"more":[177],"start":[183],"period,":[186],"lower":[188],"percentage":[189],"peak":[190],"expiratory":[191],"flow":[192],"rate,":[193],"higher":[195,215],"Global":[196],"Initiative":[197],"Asthma":[199],"treatment":[200],"step.":[201],"Older":[202],"age,":[203],"female":[204],"sex,":[205],"obesity,":[206],"smoking":[209],"also":[211],"transitioning.":[218],"Conclusion:":[219],"Our":[220],"findings":[221],"help":[222],"identify":[223],"receipt":[234],"encourage":[236],"earlier":[237],"intervention":[238],"OCS-sparing":[240],"treatments.":[241]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2024-02-03T00:00:00"}