{"id":"https://openalex.org/W4391451404","doi":"https://doi.org/10.1016/j.bpsc.2024.01.007","title":"Serotonergic Psychedelics: A Comparative Review of Efficacy, Safety, Pharmacokinetics, and Binding Profile","display_name":"Serotonergic Psychedelics: A Comparative Review of Efficacy, Safety, Pharmacokinetics, and Binding Profile","publication_year":2024,"publication_date":"2024-02-01","ids":{"openalex":"https://openalex.org/W4391451404","doi":"https://doi.org/10.1016/j.bpsc.2024.01.007","pmid":"https://pubmed.ncbi.nlm.nih.gov/38301886"},"language":"en","primary_location":{"id":"doi:10.1016/j.bpsc.2024.01.007","doi":"https://doi.org/10.1016/j.bpsc.2024.01.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpsc.2024.01.007","pdf_url":null,"source":{"id":"https://openalex.org/S2898601774","display_name":"Biological Psychiatry Cognitive Neuroscience and Neuroimaging","issn_l":"2451-9022","issn":["2451-9022","2451-9030"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Psychiatry: Cognitive Neuroscience and Neuroimaging","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.bpsc.2024.01.007","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028081191","display_name":"Friederike Holze","orcid":"https://orcid.org/0000-0003-3143-1519","observed_orcids":["https://orcid.org/0000-0003-3143-1519"]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]},{"id":"https://openalex.org/I2802542264","display_name":"University Hospital of Basel","ror":"https://ror.org/04k51q396","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802542264"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Friederike Holze","raw_affiliation_strings":["Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland. Electronic address: friederike.holze@usb.ch","Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel and University of Basel, Switzerland","Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland. Electronic address: friederike.holze@usb.ch","institution_ids":["https://openalex.org/I1850255","https://openalex.org/I2802542264"]},{"raw_affiliation_string":"Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel and University of Basel, Switzerland","institution_ids":["https://openalex.org/I1850255","https://openalex.org/I2802542264"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064947153","display_name":"Nirmal Singh","orcid":"https://orcid.org/0000-0001-6143-5284","observed_orcids":["https://orcid.org/0000-0001-6143-5284","https://orcid.org/0000-0003-2834-7746"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I4210155461","display_name":"Connecticut Mental Health Center","ror":"https://ror.org/0569bbe51","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210155461"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nirmal Singh","raw_affiliation_strings":["Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut; Clinical Neuroscience Research Unit, Connecticut Mental Health Center, New Haven, Connecticut","Clinical Neuroscience Research Unit, Connecticut Mental Health Center, New Haven, CT, USA","Dept. of Psychiatry Yale University School of Medicine, New Haven, Ct, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Yale School of Medicine, New Haven, Connecticut; Clinical Neuroscience Research Unit, Connecticut Mental Health Center, New Haven, Connecticut","institution_ids":["https://openalex.org/I32971472","https://openalex.org/I4210155461"]},{"raw_affiliation_string":"Clinical Neuroscience Research Unit, Connecticut Mental Health Center, New Haven, CT, USA","institution_ids":["https://openalex.org/I4210155461"]},{"raw_affiliation_string":"Dept. of Psychiatry Yale University School of Medicine, New Haven, Ct, USA","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071962736","display_name":"Matthias E. Liechti","orcid":"https://orcid.org/0000-0002-1765-9659","observed_orcids":["https://orcid.org/0000-0002-1765-9659"]},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]},{"id":"https://openalex.org/I2802542264","display_name":"University Hospital of Basel","ror":"https://ror.org/04k51q396","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802542264"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Matthias E. Liechti","raw_affiliation_strings":["Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland","Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel and University of Basel, Switzerland","Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel, University of Basel, Basel, Switzerland; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255","https://openalex.org/I2802542264"]},{"raw_affiliation_string":"Clinical Pharmacology and Toxicology, Department of Biomedicine and Department of Clinical Research, University Hospital Basel and University of Basel, Switzerland","institution_ids":["https://openalex.org/I1850255","https://openalex.org/I2802542264"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081806198","display_name":"Deepak Cyril D\u2019Souza","orcid":"https://orcid.org/0000-0003-3141-1462","observed_orcids":["https://orcid.org/0000-0003-3141-1462"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I4210086971","display_name":"VA Connecticut Healthcare System","ror":"https://ror.org/000rgm762","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210086971","https://openalex.org/I4210095851"]},{"id":"https://openalex.org/I4210155461","display_name":"Connecticut Mental Health Center","ror":"https://ror.org/0569bbe51","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210155461"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Deepak Cyril D\u2019Souza","raw_affiliation_strings":["Clinical Neuroscience Research Unit, Connecticut Mental Health Center, New Haven, CT, USA","Dept. of Psychiatry Yale University School of Medicine, New Haven, Ct, USA","VA Connecticut Healthcare System, West Haven, CT, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Neuroscience Research Unit, Connecticut Mental Health Center, New Haven, CT, USA","institution_ids":["https://openalex.org/I4210155461"]},{"raw_affiliation_string":"Dept. of Psychiatry Yale University School of Medicine, New Haven, Ct, USA","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"VA Connecticut Healthcare System, West Haven, CT, USA","institution_ids":["https://openalex.org/I4210086971"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5028081191","https://openalex.org/A5081806198"],"corresponding_institution_ids":["https://openalex.org/I1850255","https://openalex.org/I2802542264","https://openalex.org/I32971472","https://openalex.org/I4210086971","https://openalex.org/I4210155461"],"apc_list":{"value":3710,"currency":"USD","value_usd":3710},"apc_paid":{"value":3710,"currency":"USD","value_usd":3710},"fwci":22.7806,"has_fulltext":false,"cited_by_count":62,"citation_normalized_percentile":{"value":0.99855493,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"9","issue":"5","first_page":"472","last_page":"489"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12553","display_name":"Psychedelics and Drug Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T12553","display_name":"Psychedelics and Drug Studies","score":1.0,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serotonergic-psychedelics","display_name":"serotonergic psychedelics","score":0.8840000033378601},{"id":"https://openalex.org/keywords/psilocybin","display_name":"psilocybin","score":0.9980000257492065},{"id":"https://openalex.org/keywords/lsd","display_name":"LSD","score":0.7649999856948853},{"id":"https://openalex.org/keywords/dmt","display_name":"DMT","score":0.9440000057220459},{"id":"https://openalex.org/keywords/5-meo-dmt","display_name":"5-MeO-DMT","score":0.9980000257492065},{"id":"https://openalex.org/keywords/mescaline","display_name":"mescaline","score":1.0},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.9259999990463257},{"id":"https://openalex.org/keywords/pharmacodynamics","display_name":"pharmacodynamics","score":0.9620000123977661},{"id":"https://openalex.org/keywords/receptor-binding-profiles","display_name":"receptor binding profiles","score":0.6269999742507935},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.5899999737739563},{"id":"https://openalex.org/keywords/drug-safety","display_name":"drug safety","score":0.8690000176429749},{"id":"https://openalex.org/keywords/depression-treatment","display_name":"depression treatment","score":0.7739999890327454}],"concepts":[{"id":"https://openalex.org/C2776502132","wikidata":"https://www.wikidata.org/wiki/Q208118","display_name":"Psilocybin","level":3,"score":0.9766082167625427},{"id":"https://openalex.org/C2776125444","wikidata":"https://www.wikidata.org/wiki/Q193140","display_name":"Mescaline","level":3,"score":0.8563870191574097},{"id":"https://openalex.org/C2779871769","wikidata":"https://www.wikidata.org/wiki/Q23118","display_name":"Lysergic acid diethylamide","level":4,"score":0.8460255861282349},{"id":"https://openalex.org/C124315065","wikidata":"https://www.wikidata.org/wiki/Q194270","display_name":"Hallucinogen","level":2,"score":0.6956613659858704},{"id":"https://openalex.org/C37000724","wikidata":"https://www.wikidata.org/wiki/Q50430226","display_name":"Serotonergic","level":4,"score":0.6628363132476807},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.6367941498756409},{"id":"https://openalex.org/C111113717","wikidata":"https://www.wikidata.org/wiki/Q725307","display_name":"Pharmacodynamics","level":3,"score":0.5231174826622009},{"id":"https://openalex.org/C112705442","wikidata":"https://www.wikidata.org/wiki/Q323936","display_name":"Pharmacokinetics","level":2,"score":0.5133127570152283},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4208875894546509},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.323866069316864},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.2899613678455353},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.21719270944595337},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12257763743400574}],"mesh":[{"descriptor_ui":"D006213","descriptor_name":"Hallucinogens","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D006213","descriptor_name":"Hallucinogens","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008238","descriptor_name":"Lysergic Acid Diethylamide","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D008238","descriptor_name":"Lysergic Acid Diethylamide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D011562","descriptor_name":"Psilocybin","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":true},{"descriptor_ui":"D011562","descriptor_name":"Psilocybin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D058826","descriptor_name":"Serotonin 5-HT2 Receptor Agonists","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D058826","descriptor_name":"Serotonin 5-HT2 Receptor Agonists","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.bpsc.2024.01.007","doi":"https://doi.org/10.1016/j.bpsc.2024.01.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpsc.2024.01.007","pdf_url":null,"source":{"id":"https://openalex.org/S2898601774","display_name":"Biological Psychiatry Cognitive Neuroscience and Neuroimaging","issn_l":"2451-9022","issn":["2451-9022","2451-9030"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Psychiatry: Cognitive Neuroscience and Neuroimaging","raw_type":"journal-article"},{"id":"pmid:38301886","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38301886","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological psychiatry. Cognitive neuroscience and neuroimaging","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1016/j.bpsc.2024.01.007","doi":"https://doi.org/10.1016/j.bpsc.2024.01.007","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.bpsc.2024.01.007","pdf_url":null,"source":{"id":"https://openalex.org/S2898601774","display_name":"Biological Psychiatry Cognitive Neuroscience and Neuroimaging","issn_l":"2451-9022","issn":["2451-9022","2451-9030"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Psychiatry: Cognitive Neuroscience and Neuroimaging","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2281434497","display_name":"Concentration-effect relationship of agonistic and antagonistic serotonin 2A receptor occupancy using LSD and ketanserin","funder_award_id":"210867","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"}],"funders":[{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":127,"referenced_works":["https://openalex.org/W1489572149","https://openalex.org/W1523962342","https://openalex.org/W1824213812","https://openalex.org/W1972160704","https://openalex.org/W1973814761","https://openalex.org/W1979676351","https://openalex.org/W1983153788","https://openalex.org/W1990217434","https://openalex.org/W1997058647","https://openalex.org/W2000909913","https://openalex.org/W2006587749","https://openalex.org/W2009122980","https://openalex.org/W2009134620","https://openalex.org/W2010391271","https://openalex.org/W2026832357","https://openalex.org/W2034951640","https://openalex.org/W2037449495","https://openalex.org/W2043197532","https://openalex.org/W2048184801","https://openalex.org/W2059295576","https://openalex.org/W2062339243","https://openalex.org/W2069728618","https://openalex.org/W2074491668","https://openalex.org/W2075238613","https://openalex.org/W2077936290","https://openalex.org/W2078821747","https://openalex.org/W2079106221","https://openalex.org/W2080308963","https://openalex.org/W2080589517","https://openalex.org/W2088785539","https://openalex.org/W2091346601","https://openalex.org/W2093477837","https://openalex.org/W2096567449","https://openalex.org/W2120918936","https://openalex.org/W2122459973","https://openalex.org/W2124026487","https://openalex.org/W2137983723","https://openalex.org/W2158474067","https://openalex.org/W2161555895","https://openalex.org/W2164276826","https://openalex.org/W2164339448","https://openalex.org/W2171104921","https://openalex.org/W2243916050","https://openalex.org/W2295029219","https://openalex.org/W2318552418","https://openalex.org/W2336591896","https://openalex.org/W2340085151","https://openalex.org/W2398898762","https://openalex.org/W2408251447","https://openalex.org/W2417371067","https://openalex.org/W2424611615","https://openalex.org/W2474588055","https://openalex.org/W2506717582","https://openalex.org/W2516564083","https://openalex.org/W2558412547","https://openalex.org/W2559739670","https://openalex.org/W2582692487","https://openalex.org/W2792211781","https://openalex.org/W2792444257","https://openalex.org/W2805248302","https://openalex.org/W2808301300","https://openalex.org/W2892307734","https://openalex.org/W2914255920","https://openalex.org/W2923436703","https://openalex.org/W2936948587","https://openalex.org/W2952169207","https://openalex.org/W2981779913","https://openalex.org/W3000636165","https://openalex.org/W3046100757","https://openalex.org/W3090497377","https://openalex.org/W3093375227","https://openalex.org/W3096208965","https://openalex.org/W3105240299","https://openalex.org/W3108222140","https://openalex.org/W3112525124","https://openalex.org/W3156937150","https://openalex.org/W3157088173","https://openalex.org/W3164618783","https://openalex.org/W3165686539","https://openalex.org/W3177516331","https://openalex.org/W3179469168","https://openalex.org/W3180355975","https://openalex.org/W3210796807","https://openalex.org/W3213217218","https://openalex.org/W3213378850","https://openalex.org/W3215098003","https://openalex.org/W4200471428","https://openalex.org/W4206965048","https://openalex.org/W4211150788","https://openalex.org/W4211211437","https://openalex.org/W4211248987","https://openalex.org/W4212903385","https://openalex.org/W4214649547","https://openalex.org/W4223491164","https://openalex.org/W4226207502","https://openalex.org/W4245707768","https://openalex.org/W4281703399","https://openalex.org/W4292937262","https://openalex.org/W4293194637","https://openalex.org/W4294631080","https://openalex.org/W4294733080","https://openalex.org/W4295190209","https://openalex.org/W4306169038","https://openalex.org/W4307167512","https://openalex.org/W4308146982","https://openalex.org/W4308372082","https://openalex.org/W4308925280","https://openalex.org/W4309832620","https://openalex.org/W4311205265","https://openalex.org/W4313530670","https://openalex.org/W4321033185","https://openalex.org/W4322771105","https://openalex.org/W4327895864","https://openalex.org/W4366742769","https://openalex.org/W4377940122","https://openalex.org/W4378174725","https://openalex.org/W4378903602","https://openalex.org/W4379469019","https://openalex.org/W4381433809","https://openalex.org/W4382776629","https://openalex.org/W4385197359","https://openalex.org/W4385997324","https://openalex.org/W4386305655","https://openalex.org/W4386765441","https://openalex.org/W4387105816","https://openalex.org/W6638328730","https://openalex.org/W6639524928"],"related_works":["https://openalex.org/W4410694053","https://openalex.org/W7162805790","https://openalex.org/W193655439","https://openalex.org/W4376851995","https://openalex.org/W2789541163","https://openalex.org/W4400050497","https://openalex.org/W7163887510","https://openalex.org/W7001929291","https://openalex.org/W4315649535","https://openalex.org/W4391026101"],"abstract_inverted_index":{"Psychedelic":[0],"compounds,":[1],"including":[2],"psilocybin,":[3],"LSD":[4],"(lysergic":[5],"acid":[6],"diethylamide),":[7],"DMT":[8],"(N,N":[9],"-dimethyltryptamine),":[10],"and":[11,41,54],"5-MeO-DMT":[12],"(5-methoxy-N,N-dimethyltryptamine),":[13],"all":[14],"of":[15,49,66,97],"which":[16,112],"are":[17,22],"serotonin":[18],"2A":[19],"receptor":[20,90],"agonists,":[21],"being":[23],"investigated":[24],"as":[25],"potential":[26,96],"treatments.":[27],"This":[28],"review":[29],"aims":[30],"to":[31,43,93,104,110],"summarize":[32],"the":[33,64,94],"current":[34],"clinical":[35],"research":[36,101],"on":[37],"these":[38,98,106],"4":[39],"compounds":[40,107,113],"mescaline":[42],"guide":[44],"future":[45],"research.":[46],"Their":[47],"mechanism(s)":[48],"action,":[50],"pharmacokinetics,":[51],"pharmacodynamics,":[52],"efficacy,":[53],"safety":[55],"were":[56],"reviewed.":[57],"While":[58],"evidence":[59],"for":[60,68,117],"therapeutic":[61,95,119],"indications,":[62],"with":[63],"exception":[65],"psilocybin":[67],"depression,":[69],"is":[70,102],"still":[71],"relatively":[72],"scarce,":[73],"we":[74],"noted":[75],"no":[76],"differences":[77],"in":[78,108],"psychedelic":[79],"effects":[80],"beyond":[81],"effect":[82],"duration.":[83],"Therefore,":[84],"it":[85],"remains":[86],"unclear":[87],"whether":[88],"different":[89,118],"profiles":[91],"contribute":[92],"compounds.":[99],"More":[100],"needed":[103],"differentiate":[105],"order":[109],"inform":[111],"might":[114],"be":[115],"best":[116],"uses.":[120]},"counts_by_year":[{"year":2026,"cited_by_count":18},{"year":2025,"cited_by_count":25},{"year":2024,"cited_by_count":19}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2024-02-02T00:00:00"}
