{"id":"https://openalex.org/W4391442879","doi":"https://doi.org/10.1093/med/9780197679753.003.0019","title":"Colorectal Neoplasms","display_name":"Colorectal Neoplasms","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4391442879","doi":"https://doi.org/10.1093/med/9780197679753.003.0019"},"language":"en","primary_location":{"id":"doi:10.1093/med/9780197679753.003.0019","doi":"https://doi.org/10.1093/med/9780197679753.003.0019","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1093/med/9780197679753.003.0019","pdf_url":null,"source":{"id":"https://openalex.org/S4306463708","display_name":"Oxford University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Gastroenterology and Hepatology Board Review, 6E","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4391442923","display_name":"Mayo Clinic Gastroenterology and Hepatology Board Review, 6E"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044304609","display_name":"Derek W. Ebner","orcid":"https://orcid.org/0000-0003-0089-2507","observed_orcids":["https://orcid.org/0000-0003-0089-2507"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Derek W. Ebner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5017521990","display_name":"John B. Kisiel","orcid":"https://orcid.org/0000-0002-3840-5324","observed_orcids":["https://orcid.org/0000-0002-3840-5324","https://orcid.org/0000-0002-8624-6313"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John B. Kisiel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0331384,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"221","last_page":"229"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.9449999928474426},{"id":"https://openalex.org/keywords/colorectal-neoplasms","display_name":"colorectal neoplasia","score":0.9869999885559082},{"id":"https://openalex.org/keywords/incidence-trends","display_name":"incidence trends","score":0.8059999942779541},{"id":"https://openalex.org/keywords/young-adults","display_name":"young adults","score":0.6079999804496765},{"id":"https://openalex.org/keywords/lifetime-risk","display_name":"lifetime risk","score":0.8220000267028809},{"id":"https://openalex.org/keywords/tumor-screening","display_name":"cancer screening","score":0.6639999747276306},{"id":"https://openalex.org/keywords/surveillance-guidelines","display_name":"surveillance guidelines","score":0.8090000152587891},{"id":"https://openalex.org/keywords/cancer-prevention","display_name":"cancer prevention","score":0.8809999823570251}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3750075101852417},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.355709969997406},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.3386914134025574}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/med/9780197679753.003.0019","doi":"https://doi.org/10.1093/med/9780197679753.003.0019","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1093/med/9780197679753.003.0019","pdf_url":null,"source":{"id":"https://openalex.org/S4306463708","display_name":"Oxford University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Mayo Clinic Gastroenterology and Hepatology Board Review, 6E","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1934094702","https://openalex.org/W1966498049","https://openalex.org/W2016206649","https://openalex.org/W2037268961","https://openalex.org/W2067377514","https://openalex.org/W2083726396","https://openalex.org/W2162077547","https://openalex.org/W2619143830","https://openalex.org/W2769954443","https://openalex.org/W2911638096","https://openalex.org/W3005078169","https://openalex.org/W3005187949","https://openalex.org/W3193374122"],"related_works":["https://openalex.org/W4234676019","https://openalex.org/W4256379151","https://openalex.org/W252675244","https://openalex.org/W4246621156","https://openalex.org/W3164283026","https://openalex.org/W1986090570","https://openalex.org/W2594373254","https://openalex.org/W2765954544","https://openalex.org/W1547180521","https://openalex.org/W1969971874"],"abstract_inverted_index":{"Abstract":[0],"Colorectal":[1],"cancer":[2],"(CRC)":[3],"is":[4,20],"primarily":[5],"a":[6],"disease":[7],"of":[8,18,36,45,84],"urban,":[9],"industrialized":[10],"societies.":[11],"In":[12],"the":[13,15,33,46,57],"US,":[14],"lifetime":[16],"risk":[17],"CRC":[19,37],"similar":[21],"for":[22],"men":[23],"(4.4%)":[24],"and":[25,73],"women":[26],"(4.1%).":[27],"Recent":[28],"data":[29],"have":[30,62,70,78],"suggested":[31],"that":[32],"incidence":[34],"rates":[35],"may":[38],"be":[39],"decreasing":[40],"gradually":[41],"in":[42,50],"some":[43],"subgroups":[44],"population":[47],"but":[48],"increasing":[49],"adults":[51],"younger":[52],"than":[53],"50":[54],"years.":[55],"However,":[56],"mechanisms":[58],"underlying":[59],"these":[60],"trends":[61],"not":[63],"been":[64],"defined":[65],"completely.":[66],"Several":[67],"national":[68],"organizations":[69],"endorsed":[71],"screening":[72],"surveillance":[74],"guidelines,":[75],"which":[76],"undoubtedly":[77],"contributed":[79],"to":[80],"more":[81],"effective":[82],"prevention":[83],"CRC.":[85]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2024-02-02T00:00:00"}