{"id":"https://openalex.org/W4391070378","doi":"https://doi.org/10.1067/j.cpradiol.2024.01.003","title":"The diagnostic utility of computed tomography scans performed for febrile neutropenia in a single centre","display_name":"The diagnostic utility of computed tomography scans performed for febrile neutropenia in a single centre","publication_year":2024,"publication_date":"2024-01-21","ids":{"openalex":"https://openalex.org/W4391070378","doi":"https://doi.org/10.1067/j.cpradiol.2024.01.003","pmid":"https://pubmed.ncbi.nlm.nih.gov/38309990"},"language":"en","primary_location":{"id":"doi:10.1067/j.cpradiol.2024.01.003","doi":"https://doi.org/10.1067/j.cpradiol.2024.01.003","is_oa":true,"landing_page_url":"https://doi.org/10.1067/j.cpradiol.2024.01.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S036301882400001X","source":{"id":"https://openalex.org/S151836202","display_name":"Current Problems in Diagnostic Radiology","issn_l":"0363-0188","issn":["0363-0188","1535-6302"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Problems in Diagnostic Radiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S036301882400001X","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5037932829","display_name":"Victor Ken On Chang","orcid":"https://orcid.org/0000-0002-0755-2217","observed_orcids":["https://orcid.org/0000-0002-0755-2217"]},"institutions":[{"id":"https://openalex.org/I11701301","display_name":"Griffith University","ror":"https://ror.org/02sc3r913","country_code":"AU","type":"education","lineage":["https://openalex.org/I11701301"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"Victor K.O. Chang","raw_affiliation_strings":["School of Medicine and Dentistry, Griffith University, Gold Coast, Queensland, Australia. Electronic address: victor.chang@health.qld.gov.au","School of Medicine and Dentistry, Griffith University, Gold Coast, Queensland, Australia"],"raw_orcid":"https://orcid.org/0000-0002-0755-2217","affiliations":[{"raw_affiliation_string":"School of Medicine and Dentistry, Griffith University, Gold Coast, Queensland, Australia. Electronic address: victor.chang@health.qld.gov.au","institution_ids":["https://openalex.org/I11701301"]},{"raw_affiliation_string":"School of Medicine and Dentistry, Griffith University, Gold Coast, Queensland, Australia","institution_ids":["https://openalex.org/I11701301"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021576592","display_name":"Ee Shern Liang","orcid":"https://orcid.org/0000-0001-5320-0362","observed_orcids":["https://orcid.org/0000-0001-5320-0362"]},"institutions":[{"id":"https://openalex.org/I2801814493","display_name":"Princess Alexandra Hospital","ror":"https://ror.org/04mqb0968","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2801244131","https://openalex.org/I2801814493","https://openalex.org/I4210089726"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Ee Shern Liang","raw_affiliation_strings":["Radiology and Imaging Department, Princess Alexandra Hospital, Brisbane, Queensland, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology and Imaging Department, Princess Alexandra Hospital, Brisbane, Queensland, Australia","institution_ids":["https://openalex.org/I2801814493"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103080083","display_name":"Paul Joseph Schmidt","orcid":"https://orcid.org/0000-0001-6978-0656","observed_orcids":["https://orcid.org/0000-0001-6978-0656"]},"institutions":[{"id":"https://openalex.org/I2801814493","display_name":"Princess Alexandra Hospital","ror":"https://ror.org/04mqb0968","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I1302211766","https://openalex.org/I2801244131","https://openalex.org/I2801814493","https://openalex.org/I4210089726"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Paul Schmidt","raw_affiliation_strings":["Radiology and Imaging Department, Princess Alexandra Hospital, Brisbane, Queensland, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radiology and Imaging Department, Princess Alexandra Hospital, Brisbane, Queensland, Australia","institution_ids":["https://openalex.org/I2801814493"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5037932829"],"corresponding_institution_ids":["https://openalex.org/I11701301"],"apc_list":{"value":3140,"currency":"USD","value_usd":3140},"apc_paid":{"value":3140,"currency":"USD","value_usd":3140},"fwci":0.5315,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.63275923,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"53","issue":"3","first_page":"341","last_page":"345"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12172","display_name":"Neutropenia and Cancer Infections","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12172","display_name":"Neutropenia and Cancer Infections","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13374","display_name":"Hematological disorders and diagnostics","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/febrile-neutropenia","display_name":"febrile neutropenia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/computed-tomography","display_name":"computed tomography","score":0.9409999847412109},{"id":"https://openalex.org/keywords/cancer-patients","display_name":"cancer patients","score":0.7409999966621399},{"id":"https://openalex.org/keywords/chemotherapy","display_name":"chemotherapy","score":0.5590000152587891},{"id":"https://openalex.org/keywords/bone-marrow-transplantation","display_name":"bone marrow transplantation","score":0.8370000123977661},{"id":"https://openalex.org/keywords/pneumonia","display_name":"pneumonia","score":0.9020000100135803},{"id":"https://openalex.org/keywords/sinusitis","display_name":"sinusitis","score":0.9779999852180481},{"id":"https://openalex.org/keywords/diagnostic-yield","display_name":"diagnostic yield","score":0.6420000195503235},{"id":"https://openalex.org/keywords/low-value-imaging","display_name":"unnecessary imaging","score":0.7639999985694885}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.976900577545166},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.6607303619384766},{"id":"https://openalex.org/C2779983558","wikidata":"https://www.wikidata.org/wiki/Q9597","display_name":"Abdomen","level":2,"score":0.5533537268638611},{"id":"https://openalex.org/C2779384505","wikidata":"https://www.wikidata.org/wiki/Q17007513","display_name":"Concomitant","level":2,"score":0.5266152024269104},{"id":"https://openalex.org/C186282968","wikidata":"https://www.wikidata.org/wiki/Q1434261","display_name":"McNemar's test","level":2,"score":0.4916260838508606},{"id":"https://openalex.org/C2778357063","wikidata":"https://www.wikidata.org/wiki/Q713102","display_name":"Pelvis","level":2,"score":0.4907868802547455},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.48062676191329956},{"id":"https://openalex.org/C544519230","wikidata":"https://www.wikidata.org/wiki/Q32566","display_name":"Computed tomography","level":2,"score":0.4554138481616974},{"id":"https://openalex.org/C2779310458","wikidata":"https://www.wikidata.org/wiki/Q1405631","display_name":"Fever of unknown origin","level":2,"score":0.425346702337265},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.4196319282054901},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.40838760137557983},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.20241978764533997},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008495","descriptor_name":"Medical Oncology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012852","descriptor_name":"Sinusitis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D014057","descriptor_name":"Tomography, X-Ray Computed","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D064147","descriptor_name":"Febrile Neutropenia","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D064147","descriptor_name":"Febrile Neutropenia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1067/j.cpradiol.2024.01.003","doi":"https://doi.org/10.1067/j.cpradiol.2024.01.003","is_oa":true,"landing_page_url":"https://doi.org/10.1067/j.cpradiol.2024.01.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S036301882400001X","source":{"id":"https://openalex.org/S151836202","display_name":"Current Problems in Diagnostic Radiology","issn_l":"0363-0188","issn":["0363-0188","1535-6302"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Problems in Diagnostic Radiology","raw_type":"journal-article"},{"id":"pmid:38309990","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38309990","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current problems in diagnostic radiology","raw_type":"Observational Study"},{"id":"pmh:oai:research-repository.griffith.edu.au:10072/430620","doi":null,"is_oa":true,"landing_page_url":"https://research-repository.griffith.edu.au/bitstreams/89793969-321b-481b-8d1c-45015cf26875/download","pdf_url":null,"source":{"id":"https://openalex.org/S7407064376","display_name":"Griffith Research Online","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Journal article"}],"best_oa_location":{"id":"doi:10.1067/j.cpradiol.2024.01.003","doi":"https://doi.org/10.1067/j.cpradiol.2024.01.003","is_oa":true,"landing_page_url":"https://doi.org/10.1067/j.cpradiol.2024.01.003","pdf_url":"https://www.sciencedirect.com/science/article/pii/S036301882400001X","source":{"id":"https://openalex.org/S151836202","display_name":"Current Problems in Diagnostic Radiology","issn_l":"0363-0188","issn":["0363-0188","1535-6302"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Problems in Diagnostic Radiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4391070378.pdf","grobid_xml":"https://content.openalex.org/works/W4391070378.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1569437207","https://openalex.org/W1725388447","https://openalex.org/W1999996647","https://openalex.org/W2011910436","https://openalex.org/W2014713514","https://openalex.org/W2015434673","https://openalex.org/W2102891951","https://openalex.org/W2107994587","https://openalex.org/W2114154089","https://openalex.org/W2115687262","https://openalex.org/W2155242876","https://openalex.org/W2156229692","https://openalex.org/W2184304511","https://openalex.org/W2276548384","https://openalex.org/W2508505370","https://openalex.org/W2551431216","https://openalex.org/W2589552858","https://openalex.org/W2792999138","https://openalex.org/W2905692385","https://openalex.org/W2944759805","https://openalex.org/W2980370259","https://openalex.org/W3009307986","https://openalex.org/W3036659941","https://openalex.org/W3083688290","https://openalex.org/W3100351602","https://openalex.org/W3131607243","https://openalex.org/W3133748342","https://openalex.org/W3180922818","https://openalex.org/W4213149091","https://openalex.org/W4226150097","https://openalex.org/W4283704114","https://openalex.org/W4319769504","https://openalex.org/W4321480431","https://openalex.org/W4367318264","https://openalex.org/W4367336466"],"related_works":["https://openalex.org/W1569437207","https://openalex.org/W3180922818","https://openalex.org/W4406016195","https://openalex.org/W2156229692","https://openalex.org/W4413981511","https://openalex.org/W3100351602","https://openalex.org/W2011910436","https://openalex.org/W2900872860","https://openalex.org/W2062824127","https://openalex.org/W4391877900"],"abstract_inverted_index":{"BACKGROUND:":[0],"Computed":[1],"tomography":[2],"(CT)":[3],"imaging":[4,41,252],"has":[5],"become":[6],"a":[7,201],"first":[8],"line":[9],"investigation":[10],"for":[11,91,103,119,132],"most":[12],"cases":[13],"of":[14,24,38,63,95,136,159,204,258],"febrile":[15],"neutropenia":[16],"(FN)":[17],"which":[18],"can":[19,247],"be":[20,182],"the":[21,49,92,104,160,183],"only":[22],"sign":[23],"infection":[25,64],"in":[26,58,65,98,152,190,263],"oncology":[27,67],"patients":[28,68,232],"undergoing":[29],"active":[30],"chemotherapy":[31],"and":[32,47,55,83,110,129,170,222,245,253,260],"bone":[33],"marrow":[34],"transplants.":[35],"The":[36],"utility":[37],"routine":[39],"non-targeted":[40,54,157,259],"remains":[42],"unclear.":[43],"OBJECTIVE:":[44],"To":[45],"assess":[46],"compare":[48],"diagnostic":[50],"rate":[51,154],"between":[52,80,134],"targeted,":[53],"pan-scan":[56,261],"CT":[57,89,192,262],"identifying":[59],"an":[60],"acute":[61],"source":[62,96],"adult":[66],"with":[69],"FN.":[70,99],"MATERIALS":[71],"AND":[72],"METHODS:":[73],"A":[74],"retrospective":[75],"observational":[76],"study":[77],"was":[78,123,138,177,225],"conducted":[79],"February":[81],"2019":[82],"March":[84],"2023":[85],"on":[86],"417":[87],"consecutive":[88],"examinations":[90,196],"clinical":[93],"indication":[94],"identification":[97],"Scans":[100],"were":[101,108,112,127],"noted":[102],"anatomical":[105],"regions":[106],"that":[107],"imaged":[109],"reports":[111],"classified":[113],"as":[114],"positive,":[115],"negative":[116],"or":[117],"equivocal":[118],"infection.":[120],"Pre-existing":[121],"pathology":[122],"also":[124],"noted.":[125],"Results":[126],"tabulated":[128],"statistical":[130,227],"analyses":[131],"comparison":[133],"groups":[135],"scans":[137,147,158,210,220],"performed":[139],"using":[140],"chi-square":[141],"test.":[142],"RESULTS:":[143],"All":[144],"targeted":[145,219],"regional":[146],"had":[148,200,233],"statistically":[149],"significant":[150],"difference":[151,228],"positive":[153,205],"compared":[155,185,207,215],"to":[156,181,186,194,208,216,249],"respective":[161],"region;":[162],"chest":[163,193],"(\u03a7\u00b2(1)=18.11,":[164],"P<.001);":[165,168],"sinus":[166,195],"(\u03a7\u00b2(1)=15.36,":[167],"abdomen":[169],"pelvis":[171],"(\u03a7\u00b2(1)=5.95,":[172],"P=.01).":[173],"Pneumonia":[174],"(41.3":[175],"%)":[176,189],"much":[178],"more":[179,255],"likely":[180],"diagnosis":[184,206],"sinusitis":[187],"(16.2":[188],"concomitant":[191],"(\u03a7\u00b2(1)=45.3,":[197],"P<.001).":[198],"Pan-scans":[199],"higher":[202,217],"incidence":[203],"all-targeted":[209],"(\u03a7\u00b2(1)=4.91,":[211],"P=.03)":[212],"but":[213],"when":[214],"yield":[218],"(abdomen":[221],"chest),":[223],"there":[224],"no":[226],"(\u03a7\u00b2(1)=2.43,":[229],"P=.12).":[230],"20/54":[231],"pan-scans":[234],"despite":[235],"having":[236],"localising":[237],"symptoms.":[238],"CONCLUSION:":[239],"Imaging":[240],"guided":[241],"by":[242],"presenting":[243],"signs":[244],"symptoms":[246],"help":[248],"reduce":[250],"unnecessary":[251],"promote":[254],"judicious":[256],"use":[257],"current":[264],"practices.":[265]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-01-22T00:00:00"}