{"id":"https://openalex.org/W4390885591","doi":"https://doi.org/10.1186/s42269-024-01171-9","title":"Biochemical and microbial meta-profiling reveal the anti-cancer efficacy of Eu\u2014an endemic traditional brew of the Toto tribe from India","display_name":"Biochemical and microbial meta-profiling reveal the anti-cancer efficacy of Eu\u2014an endemic traditional brew of the Toto tribe from India","publication_year":2024,"publication_date":"2024-01-15","ids":{"openalex":"https://openalex.org/W4390885591","doi":"https://doi.org/10.1186/s42269-024-01171-9"},"language":"en","primary_location":{"id":"doi:10.1186/s42269-024-01171-9","doi":"https://doi.org/10.1186/s42269-024-01171-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s42269-024-01171-9","pdf_url":"https://bnrc.springeropen.com/counter/pdf/10.1186/s42269-024-01171-9","source":{"id":"https://openalex.org/S3034431341","display_name":"Bulletin of the National Research Centre/Bulletin of the National Research Center","issn_l":"1110-0591","issn":["1110-0591","2522-8307"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the National Research Centre","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://bnrc.springeropen.com/counter/pdf/10.1186/s42269-024-01171-9","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079792421","display_name":"Soumita Bhattacharjee","orcid":"https://orcid.org/0009-0009-1928-3614","observed_orcids":["https://orcid.org/0009-0009-1928-3614"]},"institutions":[{"id":"https://openalex.org/I56090587","display_name":"North Bengal University","ror":"https://ror.org/039w8qr24","country_code":"IN","type":"education","lineage":["https://openalex.org/I56090587"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Soumita Bhattacharjee","raw_affiliation_strings":["Biswa Bangla Genome Centre, University of North Bengal, Siliguri, India","Molecular Cytogenetics Laboratory, Department of Botany, University of North Bengal, Siliguri, 734013, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biswa Bangla Genome Centre, University of North Bengal, Siliguri, India","institution_ids":["https://openalex.org/I56090587"]},{"raw_affiliation_string":"Molecular Cytogenetics Laboratory, Department of Botany, University of North Bengal, Siliguri, 734013, India","institution_ids":["https://openalex.org/I56090587"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076494122","display_name":"Indrani Sarkar","orcid":"https://orcid.org/0000-0002-5829-4510","observed_orcids":["https://orcid.org/0000-0002-5829-4510"]},"institutions":[{"id":"https://openalex.org/I56090587","display_name":"North Bengal University","ror":"https://ror.org/039w8qr24","country_code":"IN","type":"education","lineage":["https://openalex.org/I56090587"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Indrani Sarkar","raw_affiliation_strings":["Molecular Cytogenetics Laboratory, Department of Botany, University of North Bengal, Siliguri, 734013, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Cytogenetics Laboratory, Department of Botany, University of North Bengal, Siliguri, 734013, India","institution_ids":["https://openalex.org/I56090587"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008420684","display_name":"Mahima Misti Sarkar","orcid":"https://orcid.org/0000-0001-8442-6831","observed_orcids":["https://orcid.org/0000-0001-8442-6831"]},"institutions":[{"id":"https://openalex.org/I56090587","display_name":"North Bengal University","ror":"https://ror.org/039w8qr24","country_code":"IN","type":"education","lineage":["https://openalex.org/I56090587"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mahima Misti Sarkar","raw_affiliation_strings":["Plant Biochemistry Laboratory, Department of Botany, University of North Bengal, Siliguri, 734013, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plant Biochemistry Laboratory, Department of Botany, University of North Bengal, Siliguri, 734013, India","institution_ids":["https://openalex.org/I56090587"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063664304","display_name":"Swarnendu Roy","orcid":"https://orcid.org/0000-0001-8239-6683","observed_orcids":["https://orcid.org/0000-0001-8239-6683","https://orcid.org/0009-0007-0273-9609"]},"institutions":[{"id":"https://openalex.org/I56090587","display_name":"North Bengal University","ror":"https://ror.org/039w8qr24","country_code":"IN","type":"education","lineage":["https://openalex.org/I56090587"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Swarnendu Roy","raw_affiliation_strings":["Plant Biochemistry Laboratory, Department of Botany, University of North Bengal, Siliguri, 734013, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Plant Biochemistry Laboratory, Department of Botany, University of North Bengal, Siliguri, 734013, India","institution_ids":["https://openalex.org/I56090587"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011777259","display_name":"Chandr\u00e2 Ghosh","orcid":"https://orcid.org/0000-0001-6120-1963","observed_orcids":["https://orcid.org/0000-0001-6120-1963"]},"institutions":[{"id":"https://openalex.org/I56090587","display_name":"North Bengal University","ror":"https://ror.org/039w8qr24","country_code":"IN","type":"education","lineage":["https://openalex.org/I56090587"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Chandra Ghosh","raw_affiliation_strings":["Laboratory of Tea Taxonomy and Ecology, Department of Tea Science, University of North Bengal, Siliguri, 734013, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Tea Taxonomy and Ecology, Department of Tea Science, University of North Bengal, Siliguri, 734013, India","institution_ids":["https://openalex.org/I56090587"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101871210","display_name":"Arnab Sen","orcid":"https://orcid.org/0000-0003-0502-4290","observed_orcids":["https://orcid.org/0000-0003-0502-4290"]},"institutions":[{"id":"https://openalex.org/I56090587","display_name":"North Bengal University","ror":"https://ror.org/039w8qr24","country_code":"IN","type":"education","lineage":["https://openalex.org/I56090587"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Arnab Sen","raw_affiliation_strings":["Biswa Bangla Genome Centre, University of North Bengal, Siliguri, India","Molecular Cytogenetics Laboratory, Department of Botany, University of North Bengal, Siliguri, 734013, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biswa Bangla Genome Centre, University of North Bengal, Siliguri, India","institution_ids":["https://openalex.org/I56090587"]},{"raw_affiliation_string":"Molecular Cytogenetics Laboratory, Department of Botany, University of North Bengal, Siliguri, 734013, India","institution_ids":["https://openalex.org/I56090587"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5101871210"],"corresponding_institution_ids":["https://openalex.org/I56090587"],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":0.1637,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.39112393,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":"48","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10750","display_name":"Fermentation and Sensory Analysis","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/european-union","display_name":"European Union","score":0.8610000014305115},{"id":"https://openalex.org/keywords/traditional-fermented-beverages","display_name":"traditional fermented beverages","score":0.5350000262260437},{"id":"https://openalex.org/keywords/microbial-community-analysis","display_name":"microbial community analysis","score":0.47099998593330383},{"id":"https://openalex.org/keywords/16s-rrna","display_name":"16S rRNA","score":0.8109999895095825},{"id":"https://openalex.org/keywords/probiotic-bacteria","display_name":"probiotic bacteria","score":0.9409999847412109},{"id":"https://openalex.org/keywords/fermentative-bacteria","display_name":"fermentative bacteria","score":0.7540000081062317},{"id":"https://openalex.org/keywords/nutritional-composition","display_name":"nutritional composition","score":0.8190000057220459},{"id":"https://openalex.org/keywords/free-amino-acids","display_name":"free amino acids","score":0.6269999742507935},{"id":"https://openalex.org/keywords/free-fatty-acids","display_name":"free fatty acids","score":0.9800000190734863},{"id":"https://openalex.org/keywords/human-microbe-interactions","display_name":"human-microbe interactions","score":0.6710000038146973},{"id":"https://openalex.org/keywords/bioactive-compounds","display_name":"bioactive compounds","score":0.7080000042915344},{"id":"https://openalex.org/keywords/network-pharmacology","display_name":"network pharmacology","score":0.8809999823570251},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.9390000104904175},{"id":"https://openalex.org/keywords/gastrointestinal-cancer","display_name":"gastrointestinal cancer","score":0.9010000228881836},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.8069999814033508}],"concepts":[{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.7448158860206604},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7316141724586487},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.44842132925987244},{"id":"https://openalex.org/C2775980262","wikidata":"https://www.wikidata.org/wiki/Q218870","display_name":"Prebiotic","level":2,"score":0.44737422466278076},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.4104539453983307},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.38632792234420776},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3414011001586914},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3374190628528595},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.18238726258277893},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1413266360759735}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1186/s42269-024-01171-9","doi":"https://doi.org/10.1186/s42269-024-01171-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s42269-024-01171-9","pdf_url":"https://bnrc.springeropen.com/counter/pdf/10.1186/s42269-024-01171-9","source":{"id":"https://openalex.org/S3034431341","display_name":"Bulletin of the National Research Centre/Bulletin of the National Research Center","issn_l":"1110-0591","issn":["1110-0591","2522-8307"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the National Research Centre","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:5fe7704dcf54494289335ca83729f1d8","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/5fe7704dcf54494289335ca83729f1d8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bulletin of the National Research Centre, Vol 48, Iss 1, Pp 1-12 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s42269-024-01171-9","doi":"https://doi.org/10.1186/s42269-024-01171-9","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s42269-024-01171-9","pdf_url":"https://bnrc.springeropen.com/counter/pdf/10.1186/s42269-024-01171-9","source":{"id":"https://openalex.org/S3034431341","display_name":"Bulletin of the National Research Centre/Bulletin of the National Research Center","issn_l":"1110-0591","issn":["1110-0591","2522-8307"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bulletin of the National Research Centre","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8560000061988831}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320317881","display_name":"University of North Bengal","ror":"https://ror.org/039w8qr24"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4390885591.pdf","grobid_xml":"https://content.openalex.org/works/W4390885591.grobid-xml"},"referenced_works_count":29,"referenced_works":["https://openalex.org/W1496057935","https://openalex.org/W1513495951","https://openalex.org/W1914434417","https://openalex.org/W1997317149","https://openalex.org/W1999441381","https://openalex.org/W2022518794","https://openalex.org/W2024178028","https://openalex.org/W2070753729","https://openalex.org/W2109655655","https://openalex.org/W2159675211","https://openalex.org/W2162408594","https://openalex.org/W2487920442","https://openalex.org/W2804790308","https://openalex.org/W2954864461","https://openalex.org/W3047191343","https://openalex.org/W3096586635","https://openalex.org/W3121754731","https://openalex.org/W3195237977","https://openalex.org/W4206305559","https://openalex.org/W4225481848","https://openalex.org/W4236152035","https://openalex.org/W4245344849","https://openalex.org/W4283771204","https://openalex.org/W4297989889","https://openalex.org/W4367668560","https://openalex.org/W4379967435","https://openalex.org/W4388673243","https://openalex.org/W4389195529","https://openalex.org/W4389831970"],"related_works":["https://openalex.org/W3195237977","https://openalex.org/W2809391585","https://openalex.org/W7134109212","https://openalex.org/W2976042992","https://openalex.org/W4414661091","https://openalex.org/W7127918570","https://openalex.org/W4200139037","https://openalex.org/W2791395412","https://openalex.org/W4385690119","https://openalex.org/W7171468332"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Eu":[2,119],"is":[3],"a":[4,39,75,174,222,249],"lesser-known":[5],"and":[6,112,129,158,173,199,211,252],"traditional":[7],"millet-based":[8],"fermented":[9],"brew":[10,25,52,106,139],"of":[11,27,42,50,69,82,97,110,118,123,144,186,196,214],"the":[12,43,48,54,61,67,80,94,105,121,138,142,145,159,163,183,194,209,218,231,246],"Toto":[13],"tribe":[14],"from":[15,171],"West":[16],"Bengal,":[17],"India.":[18],"The":[19,100,115,133,204],"starter":[20],"culture":[21],"used":[22],"in":[23,63,104,137,162,240],"this":[24,51,88],"consists":[26],"diverse":[28],"microflora.":[29,147],"Identifying":[30],"those":[31,180],"microbes":[32],"will":[33],"not":[34],"only":[35],"help":[36],"us":[37],"gain":[38],"deeper":[40],"understanding":[41],"brew,":[44],"but":[45],"also":[46],"quantify":[47],"impacts":[49],"on":[53,179,208],"human":[55],"system":[56],"after":[57],"consumption.":[58],"Due":[59],"to":[60,92],"progress":[62],"Illumina":[64],"sequencing":[65],"technology,":[66],"meta-profiling":[68,210],"16S":[70],"rRNA":[71],"has":[72],"emerged":[73],"as":[74,221,248],"valuable":[76],"resource":[77],"for":[78],"exploring":[79],"microbiome":[81,95],"any":[83],"sample.":[84],"We":[85],"have":[86],"utilised":[87],"tool":[89],"(V3\u2013V4":[90],"region)":[91],"study":[93,178,206],"population":[96],"Eu.":[98,164],"Results":[99],"microbial":[101],"diversity":[102],"present":[103,136,161],"was":[107],"mainly":[108],"constituted":[109],"probiotic":[111,146,223,232],"fermenting":[113],"bacteria.":[114,238],"nutrient":[116],"profiling":[117],"estimated":[120],"amount":[122],"protein,":[124],"carbohydrate,":[125],"free":[126,130],"amino":[127],"acid,":[128],"fatty":[131],"acid.":[132],"nutritional":[134,212],"substance":[135],"probably":[140],"supports":[141],"growth":[143],"Reverse":[148,226],"ecology-based":[149],"network":[150,176,242],"analysis":[151,228],"revealed":[152,182],"considerable":[153],"complementary":[154],"interaction":[155],"between":[156],"humans":[157],"microflora":[160,233],"GC\u2013MS":[165],"outlining":[166],"enlisted":[167],"thirteen":[168],"potent":[169],"compounds":[170,181],"Eu,":[172,187,215],"comprehensive":[175],"pharmacological":[177,243],"anti-cancerous":[184],"properties":[185],"especially":[188],"against":[189,236],"gastrointestinal":[190],"malignancy,":[191],"by":[192],"reducing":[193],"proliferation":[195],"malignant":[197],"cells":[198],"forming":[200],"pro-inflammatory":[201],"cytokines.":[202],"Conclusions":[203],"current":[205],"focuses":[207],"characteristics":[213],"which":[216],"highlight":[217],"beverage\u2019s":[219],"potential":[220],"health":[224],"drink.":[225],"ecology":[227],"demonstrated":[229],"that":[230],"competes":[234],"strongly":[235],"pathogenic":[237],"Additionally,":[239],"silico":[241],"research":[244],"identified":[245],"drink":[247],"potentially":[250],"health-promoting":[251],"anti-cancer":[253],"beverage.":[254]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2024-01-16T00:00:00"}