{"id":"https://openalex.org/W4390848845","doi":null,"title":"Chronic Kidney Disease: Prevention, Diagnosis, and Treatment.","display_name":"Chronic Kidney Disease: Prevention, Diagnosis, and Treatment.","publication_year":2023,"publication_date":"2023-12-01","ids":{"openalex":"https://openalex.org/W4390848845","pmid":"https://pubmed.ncbi.nlm.nih.gov/38215416"},"language":"en","primary_location":{"id":"pmid:38215416","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38215416","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American family physician","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5066675577","display_name":"Andrew J Goodbred","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew J Goodbred","raw_affiliation_strings":["St. Luke's Family Medicine Residency-Anderson, Easton, Pennsylvania; Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St. Luke's Family Medicine Residency-Anderson, Easton, Pennsylvania; Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania","institution_ids":["https://openalex.org/I84392919"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036701577","display_name":"Robert C Langan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84392919","display_name":"Temple University","ror":"https://ror.org/00kx1jb78","country_code":"US","type":"education","lineage":["https://openalex.org/I84392919"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert C Langan","raw_affiliation_strings":["St. Luke's Family Medicine Residency-Sacred Heart, Allentown, Pennsylvania; Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St. Luke's Family Medicine Residency-Sacred Heart, Allentown, Pennsylvania; Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania","institution_ids":["https://openalex.org/I84392919"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I84392919"],"apc_list":null,"apc_paid":null,"fwci":1.4549,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.81832389,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"108","issue":"6","first_page":"554","last_page":"561"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10408","display_name":"Chronic Kidney Disease and Diabetes","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":1.0},{"id":"https://openalex.org/keywords/ckd-screening","display_name":"CKD screening","score":0.8009999990463257},{"id":"https://openalex.org/keywords/estimated-glomerular-filtration-rate","display_name":"estimated glomerular filtration rate","score":0.9750000238418579},{"id":"https://openalex.org/keywords/ckd-epi-equation","display_name":"CKD-EPI equation","score":0.7689999938011169},{"id":"https://openalex.org/keywords/cystatin-c","display_name":"cystatin C","score":0.8159999847412109},{"id":"https://openalex.org/keywords/urinary-albumin-excretion","display_name":"urinary albumin excretion","score":0.8560000061988831},{"id":"https://openalex.org/keywords/end-stage-renal-disease-progression","display_name":"end-stage renal disease progression","score":0.7179999947547913},{"id":"https://openalex.org/keywords/blood-pressure-control","display_name":"blood pressure control","score":0.7889999747276306},{"id":"https://openalex.org/keywords/ace-inhibitors","display_name":"ACE inhibitors","score":0.8740000128746033},{"id":"https://openalex.org/keywords/angiotensin-receptor-blockers","display_name":"angiotensin receptor blockers","score":1.0},{"id":"https://openalex.org/keywords/sglt2-inhibitors","display_name":"SGLT2 inhibitors","score":0.9589999914169312},{"id":"https://openalex.org/keywords/metformin","display_name":"metformin","score":0.9769999980926514},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.8849999904632568},{"id":"https://openalex.org/keywords/contrast-media","display_name":"contrast media","score":0.46299999952316284},{"id":"https://openalex.org/keywords/nephrology-referral","display_name":"nephrology referral","score":0.8650000095367432},{"id":"https://openalex.org/keywords/multidisciplinary-management","display_name":"multidisciplinary management","score":0.7609999775886536}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9594723582267761},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.7885109782218933},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.7353885769844055},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6321468949317932},{"id":"https://openalex.org/C2776174234","wikidata":"https://www.wikidata.org/wiki/Q974792","display_name":"Albuminuria","level":3,"score":0.5348590612411499},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.515533447265625},{"id":"https://openalex.org/C54847362","wikidata":"https://www.wikidata.org/wiki/Q177635","display_name":"Nephrology","level":2,"score":0.5108959078788757},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.5068987011909485},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4553436040878296},{"id":"https://openalex.org/C2780306776","wikidata":"https://www.wikidata.org/wiki/Q426660","display_name":"Creatinine","level":2,"score":0.44243770837783813},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.4394038915634155},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4033384919166565},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3327377736568451},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077203","descriptor_name":"Sodium-Glucose Transporter 2 Inhibitors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005919","descriptor_name":"Glomerular Filtration Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006973","descriptor_name":"Hypertension","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D007676","descriptor_name":"Kidney Failure, Chronic","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D051436","descriptor_name":"Renal Insufficiency, Chronic","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true}],"locations_count":1,"locations":[{"id":"pmid:38215416","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38215416","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American family physician","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4391221514","https://openalex.org/W4416527063","https://openalex.org/W3206705522","https://openalex.org/W1777994377","https://openalex.org/W2977682063","https://openalex.org/W2183503591","https://openalex.org/W2118292923","https://openalex.org/W4304124019","https://openalex.org/W2406575353","https://openalex.org/W2463456562"],"abstract_inverted_index":{"Chronic":[0],"kidney":[1,39,43,67],"disease":[2,216],"(CKD)":[3],"affects":[4],"approximately":[5],"15%":[6],"of":[7,16,38,50,66,96,134,143,195,211],"the":[8,80,85,94],"U.S.":[9],"population,":[10],"and":[11,34,48,157,166,184,204,206],"many":[12],"people":[13],"are":[14,52,90],"unaware":[15],"their":[17,174],"diagnosis.":[18],"Screening":[19],"may":[20],"be":[21,77,108,120,160,186,218],"considered":[22,161],"for":[23,140,201],"patients":[24,114,141,163,189,196,207],"with":[25,115,128,164,190,197],"cardiovascular":[26],"disease,":[27,40],"diabetes":[28,169],"mellitus,":[29],"hypertension,":[30],"age":[31],"60":[32],"years":[33],"older,":[35],"family":[36],"history":[37],"previous":[41],"acute":[42],"injury,":[44],"or":[45,64,138,150],"preeclampsia.":[46],"Diagnosis":[47],"staging":[49],"CKD":[51,165,198],"based":[53],"on":[54],"estimated":[55],"glomerular":[56],"filtration":[57],"rate":[58],"(eGFR),":[59],"excessive":[60],"urinary":[61],"albumin":[62],"excretion,":[63],"evidence":[65],"parenchymal":[68],"damage":[69],"lasting":[70],"more":[71],"than":[72,124],"three":[73],"months.":[74],"eGFR":[75,112,183],"should":[76,107,119,159,185,217],"determined":[78],"using":[79,145],"CKD-EPI":[81],"creatinine":[82],"equation":[83],"without":[84],"race":[86],"variable.":[87],"Risk":[88],"calculators":[89],"available":[91],"to":[92,98,110,213,220],"estimate":[93],"risk":[95,210],"progression":[97,212],"end-stage":[99,214],"renal":[100,215],"disease.":[101],"When":[102],"possible,":[103],"serum":[104],"cystatin":[105],"C":[106],"measured":[109],"confirm":[111],"in":[113,162,188],"CKD.":[116,192],"Blood":[117],"pressure":[118,132],"maintained":[121],"at":[122,208],"less":[123,139],"140/90":[125],"mm":[126,136],"Hg,":[127],"a":[129,221],"systolic":[130],"blood":[131],"target":[133],"120":[135],"Hg":[137],"tolerant":[142],"therapy,":[144],"an":[146],"angiotensin-converting":[147],"enzyme":[148],"inhibitor":[149],"angiotensin":[151],"receptor":[152],"blocker.":[153],"Sodium-glucose":[154],"cotransporter-2":[155],"inhibitors":[156],"metformin":[158],"type":[167],"2":[168],"who":[170],"have":[171],"not":[172],"reached":[173],"glycemic":[175],"goal.":[176],"Intravenous":[177],"iodinated":[178],"contrast":[179],"media":[180],"temporarily":[181],"reduces":[182],"avoided":[187],"advanced":[191],"Interdisciplinary":[193],"management":[194],"is":[199],"important":[200],"reducing":[202],"morbidity":[203],"mortality,":[205],"high":[209],"referred":[219],"nephrologist.":[222]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2024-01-14T00:00:00"}