{"id":"https://openalex.org/W4390819201","doi":"https://doi.org/10.1097/js9.0000000000001082","title":"A radiogenomic multimodal and whole-transcriptome sequencing for preoperative prediction of axillary lymph node metastasis and drug therapeutic response in breast cancer: a retrospective, machine learning and international multicohort study","display_name":"A radiogenomic multimodal and whole-transcriptome sequencing for preoperative prediction of axillary lymph node metastasis and drug therapeutic response in breast cancer: a retrospective, machine learning and international multicohort study","publication_year":2024,"publication_date":"2024-01-11","ids":{"openalex":"https://openalex.org/W4390819201","doi":"https://doi.org/10.1097/js9.0000000000001082","pmid":"https://pubmed.ncbi.nlm.nih.gov/38215256","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/11019980"},"language":"en","primary_location":{"id":"doi:10.1097/js9.0000000000001082","doi":"https://doi.org/10.1097/js9.0000000000001082","is_oa":true,"landing_page_url":"https://doi.org/10.1097/js9.0000000000001082","pdf_url":null,"source":{"id":"https://openalex.org/S67965910","display_name":"International Journal of Surgery","issn_l":"1743-9159","issn":["1743-9159","1743-9191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-3","ki-jl-1","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1097/js9.0000000000001082","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006362016","display_name":"Jianguo Lai","orcid":"https://orcid.org/0000-0002-0120-0245","observed_orcids":["https://orcid.org/0000-0002-0120-0245"]},"institutions":[{"id":"https://openalex.org/I4210145693","display_name":"Guangdong Academy of Medical Sciences","ror":"https://ror.org/0432p8t34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145693"]},{"id":"https://openalex.org/I4210153930","display_name":"Guangdong Provincial People's Hospital","ror":"https://ror.org/045kpgw45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153930"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jianguo Lai","raw_affiliation_strings":["Department of Breast Cancer, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Yuexiu District, Guangzhou, Guangdong","Department of Breast Cancer, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University,106 Zhongshan Er Road, Yuexiu District, Guangzhou, 510080, Guangdong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast Cancer, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Yuexiu District, Guangzhou, Guangdong","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930","https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Breast Cancer, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University,106 Zhongshan Er Road, Yuexiu District, Guangzhou, 510080, Guangdong, China","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101609784","display_name":"Zijun Chen","orcid":"https://orcid.org/0000-0003-2051-2938","observed_orcids":["https://orcid.org/0000-0003-2051-2938"]},"institutions":[{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zijun Chen","raw_affiliation_strings":["The Second Clinical School of Southern Medical University, Guangzhou","The Second Clinical School of Southern Medical University, Guangzhou, 510280, Guangdong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Second Clinical School of Southern Medical University, Guangzhou","institution_ids":["https://openalex.org/I58200834"]},{"raw_affiliation_string":"The Second Clinical School of Southern Medical University, Guangzhou, 510280, Guangdong, China","institution_ids":["https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100346052","display_name":"Jie Liu","orcid":"https://orcid.org/0000-0001-6130-812X","observed_orcids":["https://orcid.org/0000-0001-6130-812X"]},"institutions":[{"id":"https://openalex.org/I4210098387","display_name":"Foshan Maternity and Child Health Care Hospital","ror":"https://ror.org/00rg8e315","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098387"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Liu","raw_affiliation_strings":["Department of Breast Cancer, Affiliated Foshan Maternity and Child Healthcare Hospital, Southern Medical University","Department of Breast Cancer, Affiliated Foshan Maternity and Child Healthcare Hospital, Southern Medical University, Foshan, Guangdong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast Cancer, Affiliated Foshan Maternity and Child Healthcare Hospital, Southern Medical University","institution_ids":["https://openalex.org/I4210098387","https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Breast Cancer, Affiliated Foshan Maternity and Child Healthcare Hospital, Southern Medical University, Foshan, Guangdong, China","institution_ids":["https://openalex.org/I4210098387","https://openalex.org/I58200834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101654686","display_name":"Chao Zhu","orcid":"https://orcid.org/0000-0002-1271-5500","observed_orcids":["https://orcid.org/0000-0002-1271-5500"]},"institutions":[{"id":"https://openalex.org/I4210164024","display_name":"First Affiliated Hospital of Nanchang University","ror":"https://ror.org/05gbwr869","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210164024"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chao Zhu","raw_affiliation_strings":["Department of Blood Transfusion, The First Affiliated Hospital of Nanchang University","Department of Blood Transfusion, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Blood Transfusion, The First Affiliated Hospital of Nanchang University","institution_ids":["https://openalex.org/I4210164024"]},{"raw_affiliation_string":"Department of Blood Transfusion, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China","institution_ids":["https://openalex.org/I4210164024"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109685021","display_name":"Haoxuan Huang","orcid":"https://orcid.org/0009-0006-7763-9090","observed_orcids":["https://orcid.org/0009-0006-7763-9090"]},"institutions":[{"id":"https://openalex.org/I4210114086","display_name":"Third Affiliated Hospital of Nanchang University","ror":"https://ror.org/02g9jg318","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210114086"]},{"id":"https://openalex.org/I4210115141","display_name":"Third Hospital of Nanchang","ror":"https://ror.org/01h439d80","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115141"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haoxuan Huang","raw_affiliation_strings":["Department of Urology, Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People\u2019s Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Third Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People\u2019s Republic of China","institution_ids":["https://openalex.org/I4210114086","https://openalex.org/I4210115141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100451652","display_name":"Ying Yi","orcid":"https://orcid.org/0000-0003-1434-1458","observed_orcids":["https://orcid.org/0000-0003-1434-1458"]},"institutions":[{"id":"https://openalex.org/I4210105740","display_name":"First People's Hospital of Foshan","ror":"https://ror.org/01cqwmh55","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105740"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ying Yi","raw_affiliation_strings":["Department of Radiology, The First People's Hospital of Foshan, Foshan, Guangdong","Department of Radiology, The First People's Hospital of Foshan, Foshan, Guangdong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, The First People's Hospital of Foshan, Foshan, Guangdong","institution_ids":["https://openalex.org/I4210105740"]},{"raw_affiliation_string":"Department of Radiology, The First People's Hospital of Foshan, Foshan, Guangdong, China","institution_ids":["https://openalex.org/I4210105740"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033016853","display_name":"Gengxi Cai","orcid":"https://orcid.org/0000-0003-0575-4314","observed_orcids":["https://orcid.org/0000-0003-0575-4314"]},"institutions":[{"id":"https://openalex.org/I4210105740","display_name":"First People's Hospital of Foshan","ror":"https://ror.org/01cqwmh55","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210105740"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Gengxi Cai","raw_affiliation_strings":["Department of Breast Surgery, The First People\u2019s Hospital of Foshan, Foshan, Guangdong","Department of Breast Surgery, The First People's Hospital of Foshan, Foshan, Guangdong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast Surgery, The First People\u2019s Hospital of Foshan, Foshan, Guangdong","institution_ids":["https://openalex.org/I4210105740"]},{"raw_affiliation_string":"Department of Breast Surgery, The First People's Hospital of Foshan, Foshan, Guangdong, China","institution_ids":["https://openalex.org/I4210105740"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100615994","display_name":"Ning Liao","orcid":"https://orcid.org/0000-0002-1780-5652","observed_orcids":["https://orcid.org/0000-0002-1780-5652"]},"institutions":[{"id":"https://openalex.org/I4210145693","display_name":"Guangdong Academy of Medical Sciences","ror":"https://ror.org/0432p8t34","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210145693"]},{"id":"https://openalex.org/I4210153930","display_name":"Guangdong Provincial People's Hospital","ror":"https://ror.org/045kpgw45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153930"]},{"id":"https://openalex.org/I58200834","display_name":"Southern Medical University","ror":"https://ror.org/01vjw4z39","country_code":"CN","type":"education","lineage":["https://openalex.org/I58200834"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Ning Liao","raw_affiliation_strings":["Department of Breast Cancer, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Yuexiu District, Guangzhou, Guangdong","Department of Breast Cancer, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University,106 Zhongshan Er Road, Yuexiu District, Guangzhou, 510080, Guangdong, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast Cancer, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Yuexiu District, Guangzhou, Guangdong","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930","https://openalex.org/I58200834"]},{"raw_affiliation_string":"Department of Breast Cancer, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University,106 Zhongshan Er Road, Yuexiu District, Guangzhou, 510080, Guangdong, China","institution_ids":["https://openalex.org/I4210145693","https://openalex.org/I4210153930","https://openalex.org/I58200834"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5006362016","https://openalex.org/A5033016853","https://openalex.org/A5100451652","https://openalex.org/A5100615994"],"corresponding_institution_ids":["https://openalex.org/I4210105740","https://openalex.org/I4210145693","https://openalex.org/I4210153930","https://openalex.org/I58200834"],"apc_list":{"value":3450,"currency":"USD","value_usd":3450},"apc_paid":{"value":3450,"currency":"USD","value_usd":3450},"fwci":6.4382,"has_fulltext":true,"cited_by_count":33,"citation_normalized_percentile":{"value":0.98096604,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"110","issue":"4","first_page":"2162","last_page":"2177"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.676800012588501,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.676800012588501,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies","score":0.3188000023365021,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11885","display_name":"MRI in cancer diagnosis","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9700000286102295},{"id":"https://openalex.org/keywords/axillary-lymph-node-metastasis","display_name":"axillary lymph node metastasis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/radiogenomics","display_name":"radiogenomics","score":0.9330000281333923},{"id":"https://openalex.org/keywords/multimodal-prediction-model","display_name":"multimodal prediction model","score":0.7210000157356262},{"id":"https://openalex.org/keywords/whole-transcriptome-sequencing","display_name":"whole transcriptome sequencing","score":0.906000018119812},{"id":"https://openalex.org/keywords/radiological-features","display_name":"radiological features","score":0.48399999737739563},{"id":"https://openalex.org/keywords/drug-response-prediction","display_name":"drug response prediction","score":0.5690000057220459},{"id":"https://openalex.org/keywords/immune-checkpoint-genes","display_name":"immune checkpoint genes","score":0.7760000228881836},{"id":"https://openalex.org/keywords/risk-stratification","display_name":"risk stratification","score":0.7760000228881836},{"id":"https://openalex.org/keywords/nomogram","display_name":"nomogram","score":0.6940000057220459},{"id":"https://openalex.org/keywords/differentially-expressed-genes","display_name":"differentially expressed genes","score":0.6439999938011169},{"id":"https://openalex.org/keywords/treatment-response-prediction","display_name":"treatment response prediction","score":0.5730000138282776},{"id":"https://openalex.org/keywords/the-cancer-genome-atlas","display_name":"TCGA","score":0.453000009059906},{"id":"https://openalex.org/keywords/the-cancer-imaging-archive","display_name":"The Cancer Imaging Archive","score":0.8709999918937683},{"id":"https://openalex.org/keywords/decision-curve-analysis","display_name":"decision curve analysis","score":0.6169999837875366},{"id":"https://openalex.org/keywords/gene-set-enrichment-analysis","display_name":"gene set enrichment analysis","score":0.7599999904632568}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8683362007141113},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.6541621685028076},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5882651209831238},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.5831092000007629},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5063585042953491},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4534977376461029},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3707770109176636},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.34540408849716187}],"mesh":[{"descriptor_ui":"D000069550","descriptor_name":"Machine Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001365","descriptor_name":"Axilla","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008207","descriptor_name":"Lymphatic Metastasis","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059467","descriptor_name":"Transcriptome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1097/js9.0000000000001082","doi":"https://doi.org/10.1097/js9.0000000000001082","is_oa":true,"landing_page_url":"https://doi.org/10.1097/js9.0000000000001082","pdf_url":null,"source":{"id":"https://openalex.org/S67965910","display_name":"International Journal of Surgery","issn_l":"1743-9159","issn":["1743-9159","1743-9191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-3","ki-jl-1","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Surgery","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:11019980","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/11019980","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC11019980/pdf/js9-110-2162.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Surg","raw_type":"Text"},{"id":"pmid:38215256","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38215256","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of surgery (London, England)","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1097/js9.0000000000001082","doi":"https://doi.org/10.1097/js9.0000000000001082","is_oa":true,"landing_page_url":"https://doi.org/10.1097/js9.0000000000001082","pdf_url":null,"source":{"id":"https://openalex.org/S67965910","display_name":"International Journal of Surgery","issn_l":"1743-9159","issn":["1743-9159","1743-9191"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-3","ki-jl-1","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Surgery","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4390819201.pdf","grobid_xml":"https://content.openalex.org/works/W4390819201.grobid-xml"},"referenced_works_count":66,"referenced_works":["https://openalex.org/W1486030395","https://openalex.org/W1543790510","https://openalex.org/W1977402770","https://openalex.org/W2013811560","https://openalex.org/W2024298740","https://openalex.org/W2026047469","https://openalex.org/W2027748666","https://openalex.org/W2036374319","https://openalex.org/W2050376635","https://openalex.org/W2079559896","https://openalex.org/W2090055464","https://openalex.org/W2095437242","https://openalex.org/W2098641762","https://openalex.org/W2103004421","https://openalex.org/W2133221537","https://openalex.org/W2142752401","https://openalex.org/W2148412188","https://openalex.org/W2171942860","https://openalex.org/W2174661749","https://openalex.org/W2177870565","https://openalex.org/W2278722429","https://openalex.org/W2465399343","https://openalex.org/W2517421365","https://openalex.org/W2542937421","https://openalex.org/W2760085125","https://openalex.org/W2761058956","https://openalex.org/W2910570496","https://openalex.org/W2921520311","https://openalex.org/W2924002300","https://openalex.org/W2936573766","https://openalex.org/W2947415066","https://openalex.org/W2957759768","https://openalex.org/W2964026708","https://openalex.org/W2973049920","https://openalex.org/W2977150399","https://openalex.org/W2981812912","https://openalex.org/W2990735016","https://openalex.org/W3006104185","https://openalex.org/W3022298391","https://openalex.org/W3022917318","https://openalex.org/W3023189324","https://openalex.org/W3025582806","https://openalex.org/W3092968006","https://openalex.org/W3110500961","https://openalex.org/W3126445005","https://openalex.org/W3128646645","https://openalex.org/W3130587675","https://openalex.org/W3200707343","https://openalex.org/W3205076722","https://openalex.org/W3208310865","https://openalex.org/W3210770785","https://openalex.org/W3212080866","https://openalex.org/W3212282753","https://openalex.org/W4220697016","https://openalex.org/W4226115663","https://openalex.org/W4280489560","https://openalex.org/W4297236910","https://openalex.org/W4297831002","https://openalex.org/W4300690596","https://openalex.org/W4306946958","https://openalex.org/W4311197359","https://openalex.org/W4319334178","https://openalex.org/W4365148021","https://openalex.org/W4386130892","https://openalex.org/W4388541093","https://openalex.org/W6845138867"],"related_works":["https://openalex.org/W4313362578","https://openalex.org/W4286684947","https://openalex.org/W4411435205","https://openalex.org/W6981269581","https://openalex.org/W4312221915","https://openalex.org/W4402319619","https://openalex.org/W4412411389","https://openalex.org/W4405383798","https://openalex.org/W4413896863","https://openalex.org/W4414238238"],"abstract_inverted_index":{"BACKGROUND:":[0],"Axillary":[1],"lymph":[2],"nodes":[3],"(ALN)":[4],"status":[5],"serves":[6],"as":[7],"a":[8,24,61,146],"crucial":[9],"prognostic":[10],"indicator":[11],"in":[12,53,227,250,264,292,344],"breast":[13],"cancer":[14],"(BC).":[15],"The":[16,69,74,161,257,332],"aim":[17],"of":[18,41,64,163,189,201,214],"this":[19,58],"study":[20],"was":[21,128,137,149,167,180,192,217,240],"to":[22,36,139,158,219,242],"construct":[23],"radiogenomic":[25,153,258,319,333],"multimodal":[26,147,259,320,323,334],"model,":[27],"based":[28,151],"on":[29,152],"machine":[30,135],"learning":[31],"and":[32,48,79,109,123,142,145,154,176,206,224,231,247,273,298,329,340],"whole-transcriptome":[33],"sequencing":[34],"(WTS),":[35],"accurately":[37],"evaluate":[38],"the":[39,87,164,170,173,177,212,229,238,251,265,274,284,318],"risk":[40,285,306],"ALN":[42],"metastasis":[43],"(ALNM),":[44],"drug":[45,207,341],"therapeutic":[46,342],"response":[47,343],"avoid":[49],"unnecessary":[50],"axillary":[51],"surgery":[52],"BC":[54,66,120,190,345],"patients.":[55,346],"METHODS:":[56],"In":[57,283],"study,":[59],"conducted":[60],"retrospective":[62],"analysis":[63,188],"1078":[65],"patients":[67,83,191,226,249],"from":[68,119],"Cancer":[70,75],"Genome":[71],"Atlas":[72],"(TCGA),":[73],"Imaging":[76],"Archive":[77],"(TCIA),":[78],"Foshan":[80,104,232],"cohort.":[81],"These":[82],"were":[84,117,289],"divided":[85],"into":[86],"TCIA":[88,93,266,275],"cohort":[89,95,100,105,111,253,267,277],"(":[90,96,101,106,112,234,254,301,313],"N":[91,97,102,107,113],"=103),":[92],"validation":[94,276],"=51),":[98],"Duke":[99,230],"=138),":[103],"=106),":[108],"TCGA":[110,252],"=680).":[114],"Radiological":[115],"features":[116,157],"extracted":[118],"radiological":[121,141,326],"images":[122],"differentially":[124],"expressed":[125],"gene":[126,195,204,293],"expression":[127],"calibrated":[129],"using":[130,169,182],"technology.":[131],"A":[132],"support":[133],"vector":[134],"model":[136,148,165,321],"employed":[138],"screen":[140],"genetic":[143],"features,":[144],"established":[150],"clinical":[155,178],"pathological":[156],"predict":[159,338],"ALNM.":[160],"accuracy":[162],"predictions":[166],"assessed":[168],"area":[171],"under":[172],"curve":[174,184],"(AUC)":[175],"benefit":[179],"measured":[181],"decision":[183],"analysis.":[185],"Risk":[186],"stratification":[187],"performed":[193],"by":[194],"set":[196],"enrichment":[197,295],"analysis,":[198,287],"differential":[199],"comparison":[200],"immune":[202],"checkpoint":[203],"expression,":[205],"sensitivity":[208],"testing.":[209],"RESULTS:":[210],"For":[211],"prediction":[213],"ALNM,":[215],"rad-score":[216],"able":[218,241],"significantly":[220,243],"differentiate":[221,244],"between":[222,245,296],"ALN-":[223,246],"ALN+":[225,248],"both":[228],"cohorts":[233],"P":[235,255,302,314],"<0.05).":[236,256,303,315],"Similarly,":[237],"gene-score":[239],"nomogram":[260,335],"demonstrated":[261],"satisfactory":[262],"performance":[263],"(AUC":[268,278],"0.82,":[269],"95%":[270,280],"CI:":[271,281],"0.74-0.91)":[272],"0.77,":[279],"0.63-0.91).":[282],"sub-stratification":[286],"there":[288],"significant":[290],"differences":[291],"pathway":[294],"high":[297],"low-risk":[299],"groups":[300,307],"Additionally,":[304],"different":[305],"may":[308],"exhibit":[309],"varying":[310],"treatment":[311],"responses":[312],"CONCLUSION:":[316],"Overall,":[317],"employs":[322],"data,":[324],"including":[325],"images,":[327],"genetic,":[328],"clinicopathological":[330],"typing.":[331],"can":[336],"precisely":[337],"ALNM":[339]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":7}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2024-01-13T00:00:00"}