{"id":"https://openalex.org/W4390768614","doi":"https://doi.org/10.1038/s41467-023-44330-8","title":"Protection against symptomatic dengue infection by neutralizing antibodies varies by infection history and infecting serotype","display_name":"Protection against symptomatic dengue infection by neutralizing antibodies varies by infection history and infecting serotype","publication_year":2024,"publication_date":"2024-01-09","ids":{"openalex":"https://openalex.org/W4390768614","doi":"https://doi.org/10.1038/s41467-023-44330-8","pmid":"https://pubmed.ncbi.nlm.nih.gov/37502957","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10371115"},"language":"en","primary_location":{"id":"doi:10.1038/s41467-023-44330-8","doi":"https://doi.org/10.1038/s41467-023-44330-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-023-44330-8","pdf_url":"https://www.nature.com/articles/s41467-023-44330-8.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41467-023-44330-8.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003315234","display_name":"Sandra Bos","orcid":"https://orcid.org/0000-0001-5036-0336","observed_orcids":["https://orcid.org/0000-0001-5036-0336"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sandra Bos","raw_affiliation_strings":["Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA. sbos@berkeley.edu","Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA"],"raw_orcid":"https://orcid.org/0000-0001-5036-0336","affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA. sbos@berkeley.edu","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5143828843","display_name":"Aaron L. Graber","orcid":"https://orcid.org/0009-0007-2623-7910","observed_orcids":["https://orcid.org/0009-0007-2623-7910"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron L. Graber","raw_affiliation_strings":["Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058408216","display_name":"Jaime Andr\u00e9s Cardona-Ospina","orcid":"https://orcid.org/0000-0003-3996-2293","observed_orcids":["https://orcid.org/0000-0003-3996-2293"]},"institutions":[{"id":"https://openalex.org/I4210154719","display_name":"Instituci\u00f3n Universitaria Visi\u00f3n de las Am\u00e9ricas","ror":"https://ror.org/04m5pzk31","country_code":"CO","type":"education","lineage":["https://openalex.org/I4210154719"]},{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["CO","US"],"is_corresponding":false,"raw_author_name":"Jaime A. Cardona-Ospina","raw_affiliation_strings":["Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA","Grupo de Investigaci\u00f3n Biomedicina, Facultad de Medicina, Instituci\u00f3n Universitaria Visi\u00f3n de las Am\u00e9ricas, Pereira, Colombia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Grupo de Investigaci\u00f3n Biomedicina, Facultad de Medicina, Instituci\u00f3n Universitaria Visi\u00f3n de las Am\u00e9ricas, Pereira, Colombia","institution_ids":["https://openalex.org/I4210154719"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040219106","display_name":"Elias Michael Duarte","orcid":"https://orcid.org/0000-0003-2541-5504","observed_orcids":["https://orcid.org/0000-0003-2541-5504"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elias M. Duarte","raw_affiliation_strings":["Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033036034","display_name":"Jos\u00e9 V\u00edctor Zambrana","orcid":"https://orcid.org/0000-0003-0107-6173","observed_orcids":["https://orcid.org/0000-0003-0107-6173"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]},{"id":"https://openalex.org/I4210137671","display_name":"Sustainable Sciences Institute","ror":"https://ror.org/02y8mb071","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210137671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jose Victor Zambrana","raw_affiliation_strings":["Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA","Sustainable Sciences Institute, Managua, Nicaragua"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA","institution_ids":["https://openalex.org/I27837315"]},{"raw_affiliation_string":"Sustainable Sciences Institute, Managua, Nicaragua","institution_ids":["https://openalex.org/I4210137671"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025838627","display_name":"Jorge A. Ru\u00edz Salinas","orcid":"https://orcid.org/0009-0006-3837-4771","observed_orcids":["https://orcid.org/0009-0006-3837-4771"]},"institutions":[{"id":"https://openalex.org/I4210137671","display_name":"Sustainable Sciences Institute","ror":"https://ror.org/02y8mb071","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210137671"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jorge A. Ru\u00edz Salinas","raw_affiliation_strings":["Sustainable Sciences Institute, Managua, Nicaragua"],"raw_orcid":"https://orcid.org/0009-0006-3837-4771","affiliations":[{"raw_affiliation_string":"Sustainable Sciences Institute, Managua, Nicaragua","institution_ids":["https://openalex.org/I4210137671"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027093597","display_name":"Reinaldo Mercado-Hernandez","orcid":"https://orcid.org/0000-0002-1098-7334","observed_orcids":["https://orcid.org/0000-0002-1098-7334"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Reinaldo Mercado-Hernandez","raw_affiliation_strings":["Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077510286","display_name":"Tulika Singh","orcid":"https://orcid.org/0000-0002-7416-7861","observed_orcids":["https://orcid.org/0000-0002-7416-7861"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tulika Singh","raw_affiliation_strings":["Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036332609","display_name":"Leah C. Katzelnick","orcid":"https://orcid.org/0000-0003-1033-6758","observed_orcids":["https://orcid.org/0000-0003-1033-6758"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210134534","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leah C. Katzelnick","raw_affiliation_strings":["Viral Epidemiology and Immunity Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Viral Epidemiology and Immunity Unit, Laboratory of Infectious Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210134534"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110995867","display_name":"Aravinda de Silva","orcid":"https://orcid.org/0000-0003-3317-5950","observed_orcids":["https://orcid.org/0000-0003-3317-5950"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aravinda de Silva","raw_affiliation_strings":["Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC, USA"],"raw_orcid":"https://orcid.org/0000-0003-3317-5950","affiliations":[{"raw_affiliation_string":"Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057357477","display_name":"Guillermina M. Kuan","orcid":"https://orcid.org/0000-0002-5251-173X","observed_orcids":["https://orcid.org/0000-0002-5251-173X"]},"institutions":[{"id":"https://openalex.org/I4210133564","display_name":"Ministerio de Salud","ror":"https://ror.org/03c09x508","country_code":"NI","type":"government","lineage":["https://openalex.org/I4210133564"]},{"id":"https://openalex.org/I4210137671","display_name":"Sustainable Sciences Institute","ror":"https://ror.org/02y8mb071","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210137671"]}],"countries":["NI","US"],"is_corresponding":false,"raw_author_name":"Guillermina Kuan","raw_affiliation_strings":["Centro de Salud S\u00f3crates Flores Vivas, Ministerio de Salud, Managua, Nicaragua","Sustainable Sciences Institute, Managua, Nicaragua"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro de Salud S\u00f3crates Flores Vivas, Ministerio de Salud, Managua, Nicaragua","institution_ids":["https://openalex.org/I4210133564"]},{"raw_affiliation_string":"Sustainable Sciences Institute, Managua, Nicaragua","institution_ids":["https://openalex.org/I4210137671"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014657699","display_name":"\u00c1ngel Balmaseda","orcid":"https://orcid.org/0000-0003-1174-4235","observed_orcids":["https://orcid.org/0000-0003-1174-4235"]},"institutions":[{"id":"https://openalex.org/I4210133564","display_name":"Ministerio de Salud","ror":"https://ror.org/03c09x508","country_code":"NI","type":"government","lineage":["https://openalex.org/I4210133564"]},{"id":"https://openalex.org/I4210137671","display_name":"Sustainable Sciences Institute","ror":"https://ror.org/02y8mb071","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210137671"]}],"countries":["NI","US"],"is_corresponding":false,"raw_author_name":"Angel Balmaseda","raw_affiliation_strings":["Laboratorio Nacional de Virolog\u00eda, Centro Nacional de Diagn\u00f3stico y Referencia, Ministerio de Salud, Managua, Nicaragua","Sustainable Sciences Institute, Managua, Nicaragua"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio Nacional de Virolog\u00eda, Centro Nacional de Diagn\u00f3stico y Referencia, Ministerio de Salud, Managua, Nicaragua","institution_ids":["https://openalex.org/I4210133564"]},{"raw_affiliation_string":"Sustainable Sciences Institute, Managua, Nicaragua","institution_ids":["https://openalex.org/I4210137671"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027442064","display_name":"Eva Harris","orcid":"https://orcid.org/0000-0002-7238-4037","observed_orcids":["https://orcid.org/0000-0002-7238-4037"]},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Eva Harris","raw_affiliation_strings":["Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA. eharris@berkeley.edu","Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA"],"raw_orcid":"https://orcid.org/0000-0002-7238-4037","affiliations":[{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA. eharris@berkeley.edu","institution_ids":["https://openalex.org/I95457486"]},{"raw_affiliation_string":"Division of Infectious Diseases and Vaccinology, School of Public Health, University of California, Berkeley, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5003315234","https://openalex.org/A5027442064"],"corresponding_institution_ids":["https://openalex.org/I95457486"],"apc_list":{"value":6790,"currency":"USD","value_usd":6790},"apc_paid":{"value":6790,"currency":"USD","value_usd":6790},"fwci":23.4884,"has_fulltext":true,"cited_by_count":57,"citation_normalized_percentile":{"value":0.99828313,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"15","issue":"1","first_page":"382","last_page":"382"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dengue-virus","display_name":"dengue virus","score":0.9929999709129333},{"id":"https://openalex.org/keywords/neutralizing-antibodies","display_name":"neutralizing antibodies","score":0.996999979019165},{"id":"https://openalex.org/keywords/serotype-specific-immunity","display_name":"serotype-specific immunity","score":0.5270000100135803},{"id":"https://openalex.org/keywords/primary-and-secondary-infection","display_name":"primary and secondary infection","score":0.6359999775886536},{"id":"https://openalex.org/keywords/dc-sign","display_name":"DC-SIGN","score":0.6510000228881836},{"id":"https://openalex.org/keywords/virion-maturation","display_name":"virion maturation","score":0.7850000262260437},{"id":"https://openalex.org/keywords/dengue-vaccine-development","display_name":"dengue vaccine development","score":0.7089999914169312},{"id":"https://openalex.org/keywords/pediatric-cohort","display_name":"pediatric cohort","score":0.7149999737739563}],"concepts":[{"id":"https://openalex.org/C533803919","wikidata":"https://www.wikidata.org/wiki/Q30953","display_name":"Dengue fever","level":2,"score":0.8677194118499756},{"id":"https://openalex.org/C10389963","wikidata":"https://www.wikidata.org/wiki/Q848328","display_name":"Serotype","level":2,"score":0.8207089900970459},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.741762638092041},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.6899559497833252},{"id":"https://openalex.org/C2779635636","wikidata":"https://www.wikidata.org/wiki/Q476209","display_name":"Dengue virus","level":3,"score":0.6282227635383606},{"id":"https://openalex.org/C2779261636","wikidata":"https://www.wikidata.org/wiki/Q7003054","display_name":"Neutralizing antibody","level":3,"score":0.5492963790893555},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.40624237060546875},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4036492705345154},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.36279457807540894}],"mesh":[],"locations_count":11,"locations":[{"id":"doi:10.1038/s41467-023-44330-8","doi":"https://doi.org/10.1038/s41467-023-44330-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-023-44330-8","pdf_url":"https://www.nature.com/articles/s41467-023-44330-8.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},{"id":"doi:10.1101/2023.06.20.23291522","doi":"https://doi.org/10.1101/2023.06.20.23291522","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2023.06.20.23291522","pdf_url":"https://www.medrxiv.org/content/medrxiv/early/2023/06/20/2023.06.20.23291522.full.pdf","source":{"id":"https://openalex.org/S3005729997","display_name":"medRxiv","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":["https://openalex.org/P4310315909"],"host_organization_lineage_names":["Cold Spring Harbor Laboratory Press"],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"medRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:10776616","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10776616","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10776616/pdf/41467_2023_Article_44330.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Commun","raw_type":"Text"},{"id":"pmid:37502957","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37502957","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"medRxiv : the preprint server for health sciences","raw_type":"Preprint"},{"id":"pmid:38195666","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38195666","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature communications","raw_type":"Journal Article"},{"id":"pmh:cdr.lib.unc.edu:xg94j4042","doi":null,"is_oa":true,"landing_page_url":"https://doi.org/10.17615/qn2c-3b29","pdf_url":"https://cdr.lib.unc.edu/downloads/d791sw63k","source":{"id":"https://openalex.org/S4306401075","display_name":"Carolina Digital Repository (University of North Carolina at Chapel Hill)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114027177","host_organization_name":"University of North Carolina at Chapel Hill","host_organization_lineage":["https://openalex.org/I114027177"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, 15(1)","raw_type":"Article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt7v04c42f","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/7v04c42f","pdf_url":"https://escholarship.org/content/qt7v04c42f/qt7v04c42f.pdf","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, vol 15, iss 1","raw_type":"article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10371115","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10371115","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"medRxiv","raw_type":"Text"},{"id":"pmh:oai:RePEc:nat:natcom:v:15:y:2024:i:1:d:10.1038_s41467-023-44330-8","doi":null,"is_oa":false,"landing_page_url":"https://www.nature.com/articles/s41467-023-44330-8","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"},{"id":"pmh:oai:doaj.org/article:f88d6ae0f5f54903a2beaf3fc606c18e","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/f88d6ae0f5f54903a2beaf3fc606c18e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)","raw_type":"article"},{"id":"doi:10.17615/qn2c-3b29","doi":"https://doi.org/10.17615/qn2c-3b29","is_oa":true,"landing_page_url":"https://doi.org/10.17615/qn2c-3b29","pdf_url":null,"source":{"id":"https://openalex.org/S7407051488","display_name":"UNC Libraries","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1038/s41467-023-44330-8","doi":"https://doi.org/10.1038/s41467-023-44330-8","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41467-023-44330-8","pdf_url":"https://www.nature.com/articles/s41467-023-44330-8.pdf","source":{"id":"https://openalex.org/S64187185","display_name":"Nature Communications","issn_l":"2041-1723","issn":["2041-1723"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Communications","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3758859768","display_name":"Epidemiological, Clinical & Immunological Studies of Zika, dengue and chikungunya","funder_award_id":"R01AI099631","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4058275830","display_name":null,"funder_award_id":"HHSN272201000026C","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G4493598524","display_name":"Dengue Human Immunology Project Consortium (DHIPC)","funder_award_id":"U19AI118610","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G5912757593","display_name":null,"funder_award_id":"P01AI106695","funder_id":"https://openalex.org/F4320306085","funder_display_name":"U.S. Department of Health and Human Services"},{"id":"https://openalex.org/G9000867875","display_name":"Living in the post-Zika world: Impact of interactions between dengue and Zika viruses on diagnostics, antibody dynamics, and correlates of disease risk","funder_award_id":"U01AI153416","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000920660","display_name":"Protective immunity following dengue virus natural infections and vaccination","funder_award_id":"P01AI106695","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320306085","display_name":"U.S. Department of Health and Human Services","ror":"https://ror.org/033jnv181"},{"id":"https://openalex.org/F4320306137","display_name":"Bill and Melinda Gates Foundation","ror":"https://ror.org/0456r8d26"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4390768614.pdf","grobid_xml":"https://content.openalex.org/works/W4390768614.grobid-xml"},"referenced_works_count":47,"referenced_works":["https://openalex.org/W1599389506","https://openalex.org/W1773048998","https://openalex.org/W1973898630","https://openalex.org/W1980640779","https://openalex.org/W1992873880","https://openalex.org/W2000351107","https://openalex.org/W2001568055","https://openalex.org/W2005217397","https://openalex.org/W2026411673","https://openalex.org/W2065486680","https://openalex.org/W2082809561","https://openalex.org/W2083311543","https://openalex.org/W2097288560","https://openalex.org/W2098558875","https://openalex.org/W2098687402","https://openalex.org/W2099973274","https://openalex.org/W2101276115","https://openalex.org/W2105529947","https://openalex.org/W2109204917","https://openalex.org/W2110058049","https://openalex.org/W2120446258","https://openalex.org/W2128221610","https://openalex.org/W2134717733","https://openalex.org/W2142371145","https://openalex.org/W2142590370","https://openalex.org/W2144505651","https://openalex.org/W2152180266","https://openalex.org/W2166561873","https://openalex.org/W2222158372","https://openalex.org/W2330650976","https://openalex.org/W2339270564","https://openalex.org/W2342696065","https://openalex.org/W2411528578","https://openalex.org/W2470285990","https://openalex.org/W2587552077","https://openalex.org/W2765619750","https://openalex.org/W2803273577","https://openalex.org/W2805511725","https://openalex.org/W2903014173","https://openalex.org/W3004141588","https://openalex.org/W3033350215","https://openalex.org/W3080379602","https://openalex.org/W3092502920","https://openalex.org/W3201153175","https://openalex.org/W4225087943","https://openalex.org/W4231879896","https://openalex.org/W4283691906"],"related_works":["https://openalex.org/W2222158372","https://openalex.org/W4400026277","https://openalex.org/W2327664245","https://openalex.org/W2124657746","https://openalex.org/W6939355266","https://openalex.org/W2152180266","https://openalex.org/W2795204357","https://openalex.org/W1968281114","https://openalex.org/W4387765957","https://openalex.org/W7171557468"],"abstract_inverted_index":{"Dengue":[0],"viruses":[1],"(DENV1-4)":[2],"are":[3,32,134],"the":[4,37,59,130,145],"most":[5],"prevalent":[6],"arboviruses":[7],"in":[8,104,166],"humans":[9],"and":[10,51,65,117,129,140,150,159,179,196],"a":[11,47,99],"major":[12],"public":[13],"health":[14],"concern.":[15],"Understanding":[16],"immune":[17,39],"mechanisms":[18],"that":[19,126,169],"modulate":[20],"DENV":[21,84],"infection":[22,157,175],"outcome":[23],"is":[24],"critical":[25],"for":[26,188,194],"vaccine":[27],"development.":[28],"Neutralizing":[29],"antibodies":[30],"(nAbs)":[31],"an":[33],"essential":[34],"component":[35],"of":[36,62,71,192],"protective":[38,131],"response,":[40],"yet":[41],"their":[42],"measurement":[43],"often":[44],"relies":[45],"on":[46,155],"single":[48],"cellular":[49],"substrate":[50,139],"partially":[52,121],"mature":[53,119,122],"virions,":[54,123],"which":[55],"does":[56],"not":[57],"capture":[58],"full":[60],"breadth":[61],"neutralizing":[63],"activity":[64],"may":[66],"lead":[67],"to":[68,88,171],"biased":[69],"estimations":[70],"nAb":[72,108,127,148,167],"potency.":[73],"Here,":[74],"we":[75,124,163],"analyze":[76],"125":[77],"samples":[78],"collected":[79],"after":[80,177],"one":[81],"or":[82,91,95,114,120],"more":[83],"infections":[85,97],"but":[86],"prior":[87,156,181],"subsequent":[89],"symptomatic":[90,174],"inapparent":[92],"DENV1,":[93],"DENV2,":[94],"DENV3":[96],"from":[98,152,173],"long-standing":[100],"pediatric":[101],"cohort":[102],"study":[103],"Nicaragua.":[105],"By":[106],"assessing":[107],"responses":[109],"using":[110],"Vero":[111],"cells":[112],"with":[113,118],"without":[115],"DC-SIGN":[116],"find":[125],"potency":[128],"NT50":[132],"cutoff":[133],"greatly":[135],"influenced":[136],"by":[137],"cell":[138],"virion":[141],"maturation":[142],"state.":[143],"Additionally,":[144],"correlation":[146],"between":[147],"titer":[149],"protection":[151,172,193],"disease":[153],"depends":[154],"history":[158],"infecting":[160],"serotype.":[161],"Finally,":[162],"uncover":[164],"variations":[165],"composition":[168],"contribute":[170],"differently":[176],"primary":[178],"secondary":[180],"infection.":[182],"These":[183],"findings":[184],"have":[185],"important":[186],"implications":[187],"identifying":[189],"antibody":[190],"correlates":[191],"vaccines":[195],"natural":[197],"infections.":[198]},"counts_by_year":[{"year":2026,"cited_by_count":16},{"year":2025,"cited_by_count":23},{"year":2024,"cited_by_count":18}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2024-01-13T00:00:00"}