{"id":"https://openalex.org/W4390744710","doi":"https://doi.org/10.3389/fnut.2023.1281879","title":"Role of vitamins A, C, D, E in cancer prevention and therapy: therapeutic potentials and mechanisms of action","display_name":"Role of vitamins A, C, D, E in cancer prevention and therapy: therapeutic potentials and mechanisms of action","publication_year":2024,"publication_date":"2024-01-11","ids":{"openalex":"https://openalex.org/W4390744710","doi":"https://doi.org/10.3389/fnut.2023.1281879","pmid":"https://pubmed.ncbi.nlm.nih.gov/38274206","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10808607"},"language":"en","primary_location":{"id":"doi:10.3389/fnut.2023.1281879","doi":"https://doi.org/10.3389/fnut.2023.1281879","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnut.2023.1281879","pdf_url":"https://www.frontiersin.org/articles/10.3389/fnut.2023.1281879/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S2596909297","display_name":"Frontiers in Nutrition","issn_l":"2296-861X","issn":["2296-861X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Nutrition","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fnut.2023.1281879/pdf?isPublishedV2=False","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050848291","display_name":"Wamidh H. Talib","orcid":"https://orcid.org/0000-0003-1942-8982","observed_orcids":["https://orcid.org/0000-0003-1942-8982"]},"institutions":[{"id":"https://openalex.org/I146367977","display_name":"Applied Science Private University","ror":"https://ror.org/01ah6nb52","country_code":"JO","type":"education","lineage":["https://openalex.org/I146367977"]}],"countries":["JO"],"is_corresponding":true,"raw_author_name":"Wamidh H. Talib","raw_affiliation_strings":["Faculty of Allied Medical Sciences, Applied Science Private University, Amman, Jordan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Allied Medical Sciences, Applied Science Private University, Amman, Jordan","institution_ids":["https://openalex.org/I146367977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111228140","display_name":"Dima Jum'Ah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146367977","display_name":"Applied Science Private University","ror":"https://ror.org/01ah6nb52","country_code":"JO","type":"education","lineage":["https://openalex.org/I146367977"]}],"countries":["JO"],"is_corresponding":false,"raw_author_name":"Dima Abdulraheem Ahmed Jum\u2019AH","raw_affiliation_strings":["Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, Jordan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, Jordan","institution_ids":["https://openalex.org/I146367977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093675011","display_name":"Zeena Shamil Attallah","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146367977","display_name":"Applied Science Private University","ror":"https://ror.org/01ah6nb52","country_code":"JO","type":"education","lineage":["https://openalex.org/I146367977"]}],"countries":["JO"],"is_corresponding":false,"raw_author_name":"Zeena Shamil Attallah","raw_affiliation_strings":["Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, Jordan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, Jordan","institution_ids":["https://openalex.org/I146367977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093675012","display_name":"Mohanned Sami Jallad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146367977","display_name":"Applied Science Private University","ror":"https://ror.org/01ah6nb52","country_code":"JO","type":"education","lineage":["https://openalex.org/I146367977"]}],"countries":["JO"],"is_corresponding":false,"raw_author_name":"Mohanned Sami Jallad","raw_affiliation_strings":["Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, Jordan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, Jordan","institution_ids":["https://openalex.org/I146367977"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020631506","display_name":"Lina Tariq Al Kury","orcid":"https://orcid.org/0000-0002-8338-7655","observed_orcids":["https://orcid.org/0000-0002-8338-7655"]},"institutions":[{"id":"https://openalex.org/I91044093","display_name":"Zayed University","ror":"https://ror.org/03snqfa66","country_code":"AE","type":"education","lineage":["https://openalex.org/I91044093"]}],"countries":["AE"],"is_corresponding":false,"raw_author_name":"Lina T. Al Kury","raw_affiliation_strings":["Department of Health Sciences, College of Natural and Health Sciences, Zayed University, Abu Dhabi, United Arab Emirates"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health Sciences, College of Natural and Health Sciences, Zayed University, Abu Dhabi, United Arab Emirates","institution_ids":["https://openalex.org/I91044093"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104227193","display_name":"Rawan W. Hadi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I146367977","display_name":"Applied Science Private University","ror":"https://ror.org/01ah6nb52","country_code":"JO","type":"education","lineage":["https://openalex.org/I146367977"]}],"countries":["JO"],"is_corresponding":false,"raw_author_name":"Rawan Wamidh Hadi","raw_affiliation_strings":["Faculty of Allied Medical Sciences, Applied Science Private University, Amman, Jordan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Allied Medical Sciences, Applied Science Private University, Amman, Jordan","institution_ids":["https://openalex.org/I146367977"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5037685826","display_name":"Asma Ismail Mahmod","orcid":"https://orcid.org/0000-0002-4591-7408","observed_orcids":["https://orcid.org/0000-0002-4591-7408"]},"institutions":[{"id":"https://openalex.org/I146367977","display_name":"Applied Science Private University","ror":"https://ror.org/01ah6nb52","country_code":"JO","type":"education","lineage":["https://openalex.org/I146367977"]}],"countries":["JO"],"is_corresponding":false,"raw_author_name":"Asma Ismail Mahmod","raw_affiliation_strings":["Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, Jordan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Pharmacy and Therapeutics, Applied Science Private University, Amman, Jordan","institution_ids":["https://openalex.org/I146367977"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5050848291"],"corresponding_institution_ids":["https://openalex.org/I146367977"],"apc_list":{"value":3295,"currency":"USD","value_usd":3295},"apc_paid":{"value":3295,"currency":"USD","value_usd":3295},"fwci":1.383,"has_fulltext":true,"cited_by_count":64,"citation_normalized_percentile":{"value":0.82340862,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"10","issue":null,"first_page":"1281879","last_page":"1281879"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.9678000211715698,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.007300000172108412,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13112","display_name":"Nutrition and Health Studies","score":0.004800000227987766,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-a","display_name":"vitamin A","score":0.9079999923706055},{"id":"https://openalex.org/keywords/vitamin-c","display_name":"vitamin C","score":1.0},{"id":"https://openalex.org/keywords/vitamin-d","display_name":"vitamin D","score":0.9929999709129333},{"id":"https://openalex.org/keywords/vitamin-e","display_name":"vitamin E","score":1.0},{"id":"https://openalex.org/keywords/cancer-prevention","display_name":"cancer prevention","score":0.8939999938011169},{"id":"https://openalex.org/keywords/cancer-therapy","display_name":"cancer therapy","score":0.9399999976158142},{"id":"https://openalex.org/keywords/mechanism-of-action","display_name":"mechanism of action","score":0.6840000152587891},{"id":"https://openalex.org/keywords/antioxidant-defense","display_name":"antioxidant defense","score":0.8859999775886536},{"id":"https://openalex.org/keywords/immune-function","display_name":"immune function","score":0.8830000162124634},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.9879999756813049},{"id":"https://openalex.org/keywords/epigenetic-regulation","display_name":"epigenetic regulation","score":0.9980000257492065},{"id":"https://openalex.org/keywords/dna-damage","display_name":"DNA damage","score":0.9760000109672546},{"id":"https://openalex.org/keywords/vitamin-supplementation","display_name":"vitamin supplementation","score":0.5619999766349792},{"id":"https://openalex.org/keywords/personalized-nutrition","display_name":"personalized nutrition","score":0.550000011920929}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6082859635353088},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6058926582336426},{"id":"https://openalex.org/C2780234812","wikidata":"https://www.wikidata.org/wiki/Q1787013","display_name":"Cancer prevention","level":3,"score":0.5848513245582581},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5781423449516296},{"id":"https://openalex.org/C2983331546","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer therapy","level":3,"score":0.4904586970806122},{"id":"https://openalex.org/C3019816032","wikidata":"https://www.wikidata.org/wiki/Q2575340","display_name":"Cancer treatment","level":3,"score":0.45676469802856445},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.43883687257766724},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.4350889325141907},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.3433064818382263},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18177810311317444},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13681289553642273},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fnut.2023.1281879","doi":"https://doi.org/10.3389/fnut.2023.1281879","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnut.2023.1281879","pdf_url":"https://www.frontiersin.org/articles/10.3389/fnut.2023.1281879/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S2596909297","display_name":"Frontiers in Nutrition","issn_l":"2296-861X","issn":["2296-861X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Nutrition","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10808607","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10808607","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10808607/pdf/fnut-10-1281879.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Nutr","raw_type":"Text"},{"id":"pmid:38274206","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38274206","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in nutrition","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:5d84aac65dab44f2887200837620760a","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/5d84aac65dab44f2887200837620760a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Nutrition, Vol 10 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fnut.2023.1281879","doi":"https://doi.org/10.3389/fnut.2023.1281879","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fnut.2023.1281879","pdf_url":"https://www.frontiersin.org/articles/10.3389/fnut.2023.1281879/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S2596909297","display_name":"Frontiers in Nutrition","issn_l":"2296-861X","issn":["2296-861X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Nutrition","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320316734","display_name":"Applied Science Private University","ror":"https://ror.org/01ah6nb52"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4390744710.pdf","grobid_xml":"https://content.openalex.org/works/W4390744710.grobid-xml"},"referenced_works_count":146,"referenced_works":["https://openalex.org/W262522641","https://openalex.org/W1541838239","https://openalex.org/W1658177200","https://openalex.org/W1948328750","https://openalex.org/W1970099681","https://openalex.org/W1974679488","https://openalex.org/W1976776496","https://openalex.org/W1982820584","https://openalex.org/W1983298423","https://openalex.org/W1999839463","https://openalex.org/W2000112260","https://openalex.org/W2010756713","https://openalex.org/W2025656727","https://openalex.org/W2030436572","https://openalex.org/W2030477906","https://openalex.org/W2042041522","https://openalex.org/W2052084403","https://openalex.org/W2054393991","https://openalex.org/W2059000386","https://openalex.org/W2061448159","https://openalex.org/W2062955140","https://openalex.org/W2068560722","https://openalex.org/W2069579177","https://openalex.org/W2076086088","https://openalex.org/W2078165473","https://openalex.org/W2102304330","https://openalex.org/W2107631420","https://openalex.org/W2108045872","https://openalex.org/W2108254285","https://openalex.org/W2108679460","https://openalex.org/W2120446217","https://openalex.org/W2129821998","https://openalex.org/W2136305436","https://openalex.org/W2140968862","https://openalex.org/W2143035222","https://openalex.org/W2143182501","https://openalex.org/W2145171396","https://openalex.org/W2147872600","https://openalex.org/W2150113096","https://openalex.org/W2151249459","https://openalex.org/W2152684651","https://openalex.org/W2164213284","https://openalex.org/W2169445476","https://openalex.org/W2170288556","https://openalex.org/W2216099563","https://openalex.org/W2264291204","https://openalex.org/W2289357943","https://openalex.org/W2332542469","https://openalex.org/W2333401880","https://openalex.org/W2346533061","https://openalex.org/W2346777110","https://openalex.org/W2399326628","https://openalex.org/W2477146603","https://openalex.org/W2541108990","https://openalex.org/W2560256042","https://openalex.org/W2561157023","https://openalex.org/W2604593715","https://openalex.org/W2605874626","https://openalex.org/W2610929028","https://openalex.org/W2738179899","https://openalex.org/W2744926723","https://openalex.org/W2745169135","https://openalex.org/W2746373891","https://openalex.org/W2746871805","https://openalex.org/W2755332177","https://openalex.org/W2761119367","https://openalex.org/W2766096623","https://openalex.org/W2770041118","https://openalex.org/W2785725996","https://openalex.org/W2786868231","https://openalex.org/W2791800613","https://openalex.org/W2792226184","https://openalex.org/W2800392143","https://openalex.org/W2802593900","https://openalex.org/W2803109776","https://openalex.org/W2807112708","https://openalex.org/W2884203872","https://openalex.org/W2885338566","https://openalex.org/W2886484391","https://openalex.org/W2889551460","https://openalex.org/W2890163881","https://openalex.org/W2891820668","https://openalex.org/W2895153455","https://openalex.org/W2901868709","https://openalex.org/W2902869582","https://openalex.org/W2909059579","https://openalex.org/W2909140157","https://openalex.org/W2909712817","https://openalex.org/W2910818445","https://openalex.org/W2913768244","https://openalex.org/W2914134682","https://openalex.org/W2938641131","https://openalex.org/W2942117124","https://openalex.org/W2947931008","https://openalex.org/W2947950552","https://openalex.org/W2967795432","https://openalex.org/W2982435542","https://openalex.org/W2995882033","https://openalex.org/W2998753509","https://openalex.org/W3008623708","https://openalex.org/W3012125601","https://openalex.org/W3017161132","https://openalex.org/W3029482838","https://openalex.org/W3032963853","https://openalex.org/W3033873591","https://openalex.org/W3036213667","https://openalex.org/W3037511248","https://openalex.org/W3046171042","https://openalex.org/W3080411302","https://openalex.org/W3080762489","https://openalex.org/W3099458069","https://openalex.org/W3109168892","https://openalex.org/W3131317793","https://openalex.org/W3132713966","https://openalex.org/W3151655442","https://openalex.org/W3158329272","https://openalex.org/W3160109639","https://openalex.org/W3169206411","https://openalex.org/W3183623224","https://openalex.org/W3185344990","https://openalex.org/W3187419526","https://openalex.org/W3200990017","https://openalex.org/W3207906338","https://openalex.org/W3208956165","https://openalex.org/W3210390963","https://openalex.org/W4200207339","https://openalex.org/W4205754721","https://openalex.org/W4206039798","https://openalex.org/W4206311380","https://openalex.org/W4221113502","https://openalex.org/W4224259286","https://openalex.org/W4281782962","https://openalex.org/W4282004669","https://openalex.org/W4283215237","https://openalex.org/W4285282868","https://openalex.org/W4290805531","https://openalex.org/W4296679447","https://openalex.org/W4306153491","https://openalex.org/W4307845377","https://openalex.org/W4308006843","https://openalex.org/W4308570787","https://openalex.org/W4312126273","https://openalex.org/W4320015564","https://openalex.org/W4366699703","https://openalex.org/W4379930532","https://openalex.org/W4380739272"],"related_works":["https://openalex.org/W4416844080","https://openalex.org/W2135347204","https://openalex.org/W7155173126","https://openalex.org/W3203131959","https://openalex.org/W4409725776","https://openalex.org/W2401504655","https://openalex.org/W4396953531","https://openalex.org/W2771435672","https://openalex.org/W7020970843","https://openalex.org/W2774113064"],"abstract_inverted_index":{"Cancer,":[0],"a":[1,63],"leading":[2],"global":[3],"cause":[4],"of":[5,46,53,66,78,90,168,187],"mortality,":[6],"arises":[7],"from":[8],"intricate":[9],"interactions":[10],"between":[11],"genetic":[12],"and":[13,33,43,68,73,100,110,113,136,141,159,173,181],"environmental":[14],"factors,":[15],"fueling":[16],"uncontrolled":[17],"cell":[18,108],"growth.":[19],"Amidst":[20],"existing":[21],"treatment":[22,142,174],"limitations,":[23],"vitamins":[24,80,93,169],"have":[25,120],"emerged":[26],"as":[27,58],"promising":[28],"candidates":[29],"for":[30,153],"cancer":[31,82,139,171],"prevention":[32,140,172],"treatment.":[34],"This":[35],"review":[36],"focuses":[37],"on":[38,81],"Vitamins":[39],"A,":[40],"C,":[41],"E,":[42],"D":[44],"because":[45],"their":[47,87,131],"protective":[48],"activity":[49],"against":[50],"various":[51],"types":[52],"cancer.":[54],"They":[55],"are":[56,127,151],"essential":[57],"human":[59],"metabolic":[60],"coenzymes.":[61],"Through":[62],"critical":[64],"exploration":[65,182],"preclinical":[67,160],"clinical":[69,117,158],"studies":[70,126],"via":[71],"PubMed":[72],"Google":[74],"Scholar,":[75],"the":[76,166],"impact":[77,94],"these":[79],"therapy":[83],"was":[84],"analyzed,":[85],"unraveling":[86],"complicated":[88],"mechanisms":[89],"action.":[91],"Interestingly,":[92],"immune":[95],"function,":[96],"antioxidant":[97],"defense,":[98],"inflammation,":[99],"epigenetic":[101],"regulation,":[102],"potentially":[103],"enhancing":[104],"outcomes":[105,155],"by":[106,148],"influencing":[107],"behavior":[109],"countering":[111],"stress":[112],"DNA":[114],"damage.":[115],"Encouraging":[116],"trial":[118],"results":[119],"been":[121],"observed;":[122],"however,":[123],"further":[124,179],"well-controlled":[125],"imperative":[128],"to":[129],"validate":[130],"effectiveness,":[132],"determine":[133],"optimal":[134,154],"dosages,":[135],"formulate":[137],"comprehensive":[138],"strategies.":[143],"Personalized":[144],"supplementation":[145],"strategies,":[146],"informed":[147],"medical":[149],"expertise,":[150],"pivotal":[152],"in":[156,170,183],"both":[157],"contexts.":[161],"Nevertheless,":[162],"conclusive":[163],"evidence":[164],"regarding":[165],"efficacy":[167],"is":[175],"still":[176],"pending,":[177],"urging":[178],"research":[180],"this":[184],"compelling":[185],"area":[186],"study.":[188]},"counts_by_year":[{"year":2026,"cited_by_count":19},{"year":2025,"cited_by_count":30},{"year":2024,"cited_by_count":15}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2024-01-13T00:00:00"}
