{"id":"https://openalex.org/W4390620172","doi":"https://doi.org/10.48184/2304-568x-2023-4-121-131","title":"Prospects for the use of layer-by-layer technology for the development of an enzyme biosensor used for milk quality control","display_name":"Prospects for the use of layer-by-layer technology for the development of an enzyme biosensor used for milk quality control","publication_year":2023,"publication_date":"2023-12-22","ids":{"openalex":"https://openalex.org/W4390620172","doi":"https://doi.org/10.48184/2304-568x-2023-4-121-131"},"language":"en","primary_location":{"id":"doi:10.48184/2304-568x-2023-4-121-131","doi":"https://doi.org/10.48184/2304-568x-2023-4-121-131","is_oa":true,"landing_page_url":"https://doi.org/10.48184/2304-568x-2023-4-121-131","pdf_url":"https://www.vestnik-atu.kz/jour/article/download/1879/582","source":{"id":"https://openalex.org/S4210234465","display_name":"The Journal of Almaty Technological University","issn_l":"2304-568X","issn":["2304-568X","2710-0839"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Almaty Technological University","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.vestnik-atu.kz/jour/article/download/1879/582","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011721178","display_name":"\u0410\u0439\u0442\u0431\u0435\u043a \u041a\u0430\u043b\u0438\u0435\u0432\u0438\u0447 \u041a\u0430\u043a\u0438\u043c\u043e\u0432","orcid":"https://orcid.org/0000-0002-9607-1684","observed_orcids":["https://orcid.org/0000-0002-9607-1684"]},"institutions":[{"id":"https://openalex.org/I4210159258","display_name":"Shakarim University","ror":"https://ror.org/052q3p191","country_code":"KZ","type":"education","lineage":["https://openalex.org/I4210159258"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"\u0410. Kakimov","raw_affiliation_strings":["NPJSC \u00abShakarim University of Semey\u00bb"],"raw_orcid":"https://orcid.org/0000-0002-9607-1684","affiliations":[{"raw_affiliation_string":"NPJSC \u00abShakarim University of Semey\u00bb","institution_ids":["https://openalex.org/I4210159258"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041754490","display_name":"\u041a\u043b\u0430\u0440\u0430 \u0421\u0430\u0443\u044b\u043a\u043e\u0432\u043d\u0430 \u0416\u0430\u0440\u044b\u043a\u0431\u0430\u0441\u043e\u0432\u0430","orcid":"https://orcid.org/0000-0002-2027-3183","observed_orcids":["https://orcid.org/0000-0002-2027-3183"]},"institutions":[{"id":"https://openalex.org/I4387152926","display_name":"Alikhan Bokeikhan University","ror":"https://ror.org/00zgt9663","country_code":"KZ","type":"education","lineage":["https://openalex.org/I4387152926"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"\u041a. Zharykbassova","raw_affiliation_strings":["Alikhan Bokeikhan University"],"raw_orcid":"https://orcid.org/0000-0002-2027-3183","affiliations":[{"raw_affiliation_string":"Alikhan Bokeikhan University","institution_ids":["https://openalex.org/I4387152926"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085651783","display_name":"Gulnara Tulkebayeva","orcid":"https://orcid.org/0000-0002-1121-5520","observed_orcids":["https://orcid.org/0000-0002-1121-5520"]},"institutions":[{"id":"https://openalex.org/I4210159258","display_name":"Shakarim University","ror":"https://ror.org/052q3p191","country_code":"KZ","type":"education","lineage":["https://openalex.org/I4210159258"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"G. Tulkebayeva","raw_affiliation_strings":["NPJSC \u00abShakarim University of Semey\u00bb"],"raw_orcid":"https://orcid.org/0000-0002-1121-5520","affiliations":[{"raw_affiliation_string":"NPJSC \u00abShakarim University of Semey\u00bb","institution_ids":["https://openalex.org/I4210159258"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081093598","display_name":"Zhainagul Kakimova","orcid":"https://orcid.org/0000-0002-3501-3042","observed_orcids":["https://orcid.org/0000-0002-3501-3042"]},"institutions":[{"id":"https://openalex.org/I4210159258","display_name":"Shakarim University","ror":"https://ror.org/052q3p191","country_code":"KZ","type":"education","lineage":["https://openalex.org/I4210159258"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Zh. Kakimova","raw_affiliation_strings":["NPJSC \u00abShakarim University of Semey\u00bb"],"raw_orcid":"https://orcid.org/0000-0002-3501-3042","affiliations":[{"raw_affiliation_string":"NPJSC \u00abShakarim University of Semey\u00bb","institution_ids":["https://openalex.org/I4210159258"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056334887","display_name":"Yerlan Zharykbasov","orcid":"https://orcid.org/0000-0001-9707-0539","observed_orcids":["https://orcid.org/0000-0001-9707-0539"]},"institutions":[{"id":"https://openalex.org/I4210159258","display_name":"Shakarim University","ror":"https://ror.org/052q3p191","country_code":"KZ","type":"education","lineage":["https://openalex.org/I4210159258"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"Ye. Zharykbassov","raw_affiliation_strings":["NPJSC \u00abShakarim University of Semey\u00bb"],"raw_orcid":"https://orcid.org/0000-0001-9707-0539","affiliations":[{"raw_affiliation_string":"NPJSC \u00abShakarim University of Semey\u00bb","institution_ids":["https://openalex.org/I4210159258"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089613718","display_name":"\u0413\u0443\u043b\u044c\u043c\u0438\u0440\u0430 \u041e\u0440\u0430\u0437\u0431\u0435\u043a\u043e\u0432\u043d\u0430 \u041c\u0438\u0440\u0430\u0448\u0435\u0432\u0430","orcid":"https://orcid.org/0000-0003-4286-4563","observed_orcids":["https://orcid.org/0000-0003-4286-4563"]},"institutions":[{"id":"https://openalex.org/I4210159258","display_name":"Shakarim University","ror":"https://ror.org/052q3p191","country_code":"KZ","type":"education","lineage":["https://openalex.org/I4210159258"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"G. Mirasheva","raw_affiliation_strings":["NPJSC \u00abShakarim University of Semey\u00bb"],"raw_orcid":"https://orcid.org/0000-0003-4286-4563","affiliations":[{"raw_affiliation_string":"NPJSC \u00abShakarim University of Semey\u00bb","institution_ids":["https://openalex.org/I4210159258"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039830383","display_name":"\u041d\u0430\u0434\u0438\u0440 \u041a\u0430\u0434\u044b\u0440\u043e\u0432\u0438\u0447 \u0418\u0431\u0440\u0430\u0433\u0438\u043c\u043e\u0432","orcid":"https://orcid.org/0000-0001-9607-823X","observed_orcids":["https://orcid.org/0000-0001-9607-823X"]},"institutions":[{"id":"https://openalex.org/I4210159258","display_name":"Shakarim University","ror":"https://ror.org/052q3p191","country_code":"KZ","type":"education","lineage":["https://openalex.org/I4210159258"]}],"countries":["KZ"],"is_corresponding":false,"raw_author_name":"N. Ibragimov","raw_affiliation_strings":["NPJSC \u00abShakarim University of Semey\u00bb"],"raw_orcid":"https://orcid.org/0000-0001-9607-823X","affiliations":[{"raw_affiliation_string":"NPJSC \u00abShakarim University of Semey\u00bb","institution_ids":["https://openalex.org/I4210159258"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":6500,"currency":"KZT","value_usd":null},"apc_paid":null,"fwci":0.0959,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.23473698,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":null,"issue":"4","first_page":"121","last_page":"131"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.5458999872207642,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.5458999872207642,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.2996000051498413,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.03849999979138374,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/enzyme-biosensors","display_name":"enzyme biosensor","score":0.9670000076293945},{"id":"https://openalex.org/keywords/milk-quality-control","display_name":"milk quality control","score":0.8659999966621399},{"id":"https://openalex.org/keywords/cadmium","display_name":"cadmium","score":0.5379999876022339},{"id":"https://openalex.org/keywords/lead","display_name":"lead","score":1.0},{"id":"https://openalex.org/keywords/heavy-metal-detection","display_name":"heavy metal detection","score":0.8140000104904175},{"id":"https://openalex.org/keywords/catalase","display_name":"catalase","score":0.8669999837875366},{"id":"https://openalex.org/keywords/acetylcholinesterase","display_name":"acetylcholinesterase","score":0.9419999718666077},{"id":"https://openalex.org/keywords/enzyme-immobilization","display_name":"enzyme immobilization","score":0.9629999995231628},{"id":"https://openalex.org/keywords/food-safety","display_name":"food safety","score":0.878000020980835},{"id":"https://openalex.org/keywords/food-contamination","display_name":"food contamination","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.855237603187561},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5583246350288391},{"id":"https://openalex.org/C33633552","wikidata":"https://www.wikidata.org/wiki/Q904145","display_name":"Immobilized enzyme","level":3,"score":0.5397075414657593},{"id":"https://openalex.org/C206139338","wikidata":"https://www.wikidata.org/wiki/Q192355","display_name":"Raw material","level":2,"score":0.4956890344619751},{"id":"https://openalex.org/C2777289219","wikidata":"https://www.wikidata.org/wiki/Q7632154","display_name":"Substrate (aquarium)","level":2,"score":0.4714844226837158},{"id":"https://openalex.org/C82685317","wikidata":"https://www.wikidata.org/wiki/Q19829510","display_name":"Pollutant","level":2,"score":0.45197367668151855},{"id":"https://openalex.org/C2778979269","wikidata":"https://www.wikidata.org/wiki/Q106951292","display_name":"Catalase","level":3,"score":0.44829463958740234},{"id":"https://openalex.org/C112570922","wikidata":"https://www.wikidata.org/wiki/Q60528603","display_name":"Contamination","level":2,"score":0.4179364740848541},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.3984498977661133},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.37138330936431885},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3616985082626343},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.36037760972976685},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3235969543457031},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24103689193725586},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.20047801733016968},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.17069381475448608},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11743152141571045},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.07719257473945618},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.48184/2304-568x-2023-4-121-131","doi":"https://doi.org/10.48184/2304-568x-2023-4-121-131","is_oa":true,"landing_page_url":"https://doi.org/10.48184/2304-568x-2023-4-121-131","pdf_url":"https://www.vestnik-atu.kz/jour/article/download/1879/582","source":{"id":"https://openalex.org/S4210234465","display_name":"The Journal of Almaty Technological University","issn_l":"2304-568X","issn":["2304-568X","2710-0839"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Almaty Technological University","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.48184/2304-568x-2023-4-121-131","doi":"https://doi.org/10.48184/2304-568x-2023-4-121-131","is_oa":true,"landing_page_url":"https://doi.org/10.48184/2304-568x-2023-4-121-131","pdf_url":"https://www.vestnik-atu.kz/jour/article/download/1879/582","source":{"id":"https://openalex.org/S4210234465","display_name":"The Journal of Almaty Technological University","issn_l":"2304-568X","issn":["2304-568X","2710-0839"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Almaty Technological University","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4390620172.pdf","grobid_xml":"https://content.openalex.org/works/W4390620172.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1979094871","https://openalex.org/W2790685730","https://openalex.org/W2920618573","https://openalex.org/W2960495989","https://openalex.org/W2987175501","https://openalex.org/W3004770578","https://openalex.org/W3081426492","https://openalex.org/W3126951392","https://openalex.org/W3148246786","https://openalex.org/W3159159109","https://openalex.org/W3161460920","https://openalex.org/W3172762785","https://openalex.org/W3175068815","https://openalex.org/W3205714108","https://openalex.org/W4308345816"],"related_works":["https://openalex.org/W7128519906","https://openalex.org/W2888708245","https://openalex.org/W2152541049","https://openalex.org/W2182264989","https://openalex.org/W3001581044","https://openalex.org/W7120758547","https://openalex.org/W2036167206","https://openalex.org/W2796685003","https://openalex.org/W2317300477","https://openalex.org/W4311958221"],"abstract_inverted_index":{"This":[0],"article":[1],"presents":[2],"the":[3,9,16,38,44,64,67,70,76,82,97,119,154,162,173,177,182,185,194,199,209,226,245,248,259,267,275,287],"results":[4,257],"of":[5,11,18,20,40,46,66,72,78,84,86,93,99,106,121,131,142,164,176,181,184,201,206,228,233,258,269,277,280],"scientific":[6,107],"research":[7,260],"on":[8,63,161,247],"development":[10,77,92],"a":[12,30,79,94,204,213,219,223,230],"biosensor":[13,31,80,95],"system":[14],"for":[15,81,96,149,153,225],"determination":[17,98],"salts":[19,85],"heavy":[21,87],"metals":[22,88],"(cadmium":[23],"and":[24,43,51,69,108,124,273,283],"lead)":[25],"in":[26,75,89,102,191,266,274],"milk.":[27,90],"When":[28],"developing":[29],"system,":[32],"much":[33],"attention":[34,115],"is":[35,105,116,147],"paid":[36,117],"to":[37,118,171,198,243,263],"selection":[39,65],"biological":[41,214],"material":[42,215],"method":[45,71,196,200],"their":[47],"stabilization":[48],"using":[49],"physical":[50],"chemical":[52],"forces,":[53],"namely,":[54],"immobilization.":[55],"In":[56,111],"this":[57],"regard,":[58],"studies":[59,158],"were":[60],"carried":[61,189],"out":[62,190],"enzyme":[68,178,187,211,246,254],"its":[73],"immobilization":[74,227],"detection":[83],"The":[91,238,256],"toxic":[100,128],"elements":[101],"food":[103,125,145,155,270,284],"products":[104,126,146,285],"practical":[109],"importance.":[110],"world":[112],"practice,":[113],"special":[114],"contamination":[120],"raw":[122,143,281],"materials":[123,282],"with":[127,193],"chemicals,":[129],"mainly":[130],"anthropogenic":[132],"origin,":[133],"which":[134],"are":[135,159,261],"persistent":[136],"organic":[137],"pollutants.":[138],"Therefore,":[139],"quality":[140],"control":[141],"materials,":[144],"important":[148],"consumers,":[150],"and,":[151],"accordingly,":[152],"industry.":[156],"Experimental":[157],"based":[160],"methods":[163],"Filippova":[165],"A.":[166],"M.,":[167],"Vorobieva":[168],"O.":[169],"V.":[170],"determine":[172],"specific":[174],"activity":[175,183],"acetylcholinesterase.":[179],"Determination":[180],"catalase":[186,210],"was":[188,216,236,241],"accordance":[192],"gasometric":[195],"according":[197],"Warburg.":[202],"As":[203,222],"result":[205],"experimental":[207],"studies,":[208],"as":[212,218],"chosen":[217],"sensitive":[220],"element.":[221],"carrier":[224],"enzymes,":[229],"5-bilayer":[231],"combination":[232],"\"chitosan-sodium":[234],"alginate\"":[235],"selected.":[237],"layer-by-layer":[239],"technology":[240],"used":[242],"immobilize":[244],"substrate":[249],"surface":[250],"when":[251],"creating":[252],"an":[253],"biosensor.":[255],"recommended":[262],"be":[264],"applied":[265],"study":[268],"safety":[271,278],"issues":[272],"assessment":[276],"indicators":[279],"by":[286],"express":[288],"method.":[289]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2024-01-07T00:00:00"}