{"id":"https://openalex.org/W4390619633","doi":"https://doi.org/10.1016/j.dci.2024.105136","title":"The effects of primary and secondary bacterial exposure on the seahorse (Hippocampus erectus) immune response","display_name":"The effects of primary and secondary bacterial exposure on the seahorse (Hippocampus erectus) immune response","publication_year":2024,"publication_date":"2024-01-05","ids":{"openalex":"https://openalex.org/W4390619633","doi":"https://doi.org/10.1016/j.dci.2024.105136","pmid":"https://pubmed.ncbi.nlm.nih.gov/38185263"},"language":"en","primary_location":{"id":"doi:10.1016/j.dci.2024.105136","doi":"https://doi.org/10.1016/j.dci.2024.105136","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.dci.2024.105136","pdf_url":null,"source":{"id":"https://openalex.org/S81563257","display_name":"Developmental & Comparative Immunology","issn_l":"0145-305X","issn":["0145-305X","1879-0089"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental & Comparative Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.dci.2024.105136","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081875338","display_name":"Jamie Parker","orcid":"https://orcid.org/0000-0002-9832-9239","observed_orcids":["https://orcid.org/0000-0002-9832-9239"]},"institutions":[{"id":"https://openalex.org/I32021983","display_name":"Christian-Albrechts-Universit\u00e4t zu Kiel","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Jamie Parker","raw_affiliation_strings":["Marine Evolutionary Biology, Christian-Albrechts-University, D-24118, Kiel, Germany. Electronic address: jparker@zoologie.uni-kiel.de","Marine Evolutionary Biology, Christian-Albrechts-University, D-24118, Kiel, Germany"],"raw_orcid":"https://orcid.org/0000-0002-9832-9239","affiliations":[{"raw_affiliation_string":"Marine Evolutionary Biology, Christian-Albrechts-University, D-24118, Kiel, Germany. Electronic address: jparker@zoologie.uni-kiel.de","institution_ids":["https://openalex.org/I32021983"]},{"raw_affiliation_string":"Marine Evolutionary Biology, Christian-Albrechts-University, D-24118, Kiel, Germany","institution_ids":["https://openalex.org/I32021983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039286623","display_name":"Silke\u2010Mareike Marten","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32021983","display_name":"Christian-Albrechts-Universit\u00e4t zu Kiel","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Silke-Mareike Marten","raw_affiliation_strings":["Marine Evolutionary Biology, Christian-Albrechts-University, D-24118, Kiel, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Evolutionary Biology, Christian-Albrechts-University, D-24118, Kiel, Germany","institution_ids":["https://openalex.org/I32021983"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080949093","display_name":"Tadhg C. \u00d3 Corcora","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I34403800","display_name":"GEOMAR Helmholtz Centre for Ocean Research Kiel","ror":"https://ror.org/02h2x0161","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I34403800"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Tadhg C. \u00d3 Corcora","raw_affiliation_strings":["Marine Evolutionary Ecology, GEOMAR Helmholtz Centre for Ocean Research Kiel, D-24105, Kiel, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Evolutionary Ecology, GEOMAR Helmholtz Centre for Ocean Research Kiel, D-24105, Kiel, Germany","institution_ids":["https://openalex.org/I34403800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011235796","display_name":"Jelena Rajkov","orcid":"https://orcid.org/0000-0003-1533-2430","observed_orcids":["https://orcid.org/0000-0003-1533-2430"]},"institutions":[{"id":"https://openalex.org/I34403800","display_name":"GEOMAR Helmholtz Centre for Ocean Research Kiel","ror":"https://ror.org/02h2x0161","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I34403800"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Jelena Rajkov","raw_affiliation_strings":["Marine Evolutionary Ecology, GEOMAR Helmholtz Centre for Ocean Research Kiel, D-24105, Kiel, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Evolutionary Ecology, GEOMAR Helmholtz Centre for Ocean Research Kiel, D-24105, Kiel, Germany","institution_ids":["https://openalex.org/I34403800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091882746","display_name":"Arseny Dubin","orcid":"https://orcid.org/0000-0001-8360-5475","observed_orcids":["https://orcid.org/0000-0001-8360-5475"]},"institutions":[{"id":"https://openalex.org/I32021983","display_name":"Christian-Albrechts-Universit\u00e4t zu Kiel","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Arseny Dubin","raw_affiliation_strings":["Marine Evolutionary Biology, Christian-Albrechts-University, D-24118, Kiel, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Evolutionary Biology, Christian-Albrechts-University, D-24118, Kiel, Germany","institution_ids":["https://openalex.org/I32021983"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008580900","display_name":"Olivia Roth","orcid":"https://orcid.org/0000-0002-7349-7797","observed_orcids":["https://orcid.org/0000-0002-7349-7797","https://orcid.org/0000-0003-0582-1011"]},"institutions":[{"id":"https://openalex.org/I32021983","display_name":"Christian-Albrechts-Universit\u00e4t zu Kiel","ror":"https://ror.org/04v76ef78","country_code":"DE","type":"education","lineage":["https://openalex.org/I32021983"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Olivia Roth","raw_affiliation_strings":["Marine Evolutionary Biology, Christian-Albrechts-University, D-24118, Kiel, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Marine Evolutionary Biology, Christian-Albrechts-University, D-24118, Kiel, Germany","institution_ids":["https://openalex.org/I32021983"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5081875338"],"corresponding_institution_ids":["https://openalex.org/I32021983"],"apc_list":{"value":3480,"currency":"USD","value_usd":3480},"apc_paid":{"value":3480,"currency":"USD","value_usd":3480},"fwci":0.2919,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.45055824,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"153","issue":null,"first_page":"105136","last_page":"105136"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.6044999957084656,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota","score":0.6044999957084656,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13892","display_name":"Aquatic life and conservation","score":0.35350000858306885,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms","score":0.03269999846816063,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/seahorse","display_name":"seahorse","score":0.8899999856948853},{"id":"https://openalex.org/keywords/hippocampus-erectus","display_name":"Hippocampus erectus","score":1.0},{"id":"https://openalex.org/keywords/syngnathidae","display_name":"Syngnathidae","score":0.9020000100135803},{"id":"https://openalex.org/keywords/immune-priming","display_name":"immune priming","score":0.8809999823570251},{"id":"https://openalex.org/keywords/vibrio-aestuarianus","display_name":"Vibrio aestuarianus","score":0.9430000185966492},{"id":"https://openalex.org/keywords/tenacibaculum-maritimum","display_name":"Tenacibaculum maritimum","score":1.0},{"id":"https://openalex.org/keywords/heat-killed-bacteria","display_name":"heat-killed bacteria","score":0.8209999799728394},{"id":"https://openalex.org/keywords/gill-transcriptome","display_name":"gill transcriptome","score":0.8560000061988831},{"id":"https://openalex.org/keywords/mhc-class-ii","display_name":"MHC class II","score":0.8109999895095825},{"id":"https://openalex.org/keywords/adaptive-immune-response","display_name":"adaptive immune response","score":0.871999979019165},{"id":"https://openalex.org/keywords/t-cell-mediated-immunity","display_name":"T cell immunity","score":0.902999997138977},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.7229999899864197},{"id":"https://openalex.org/keywords/major-histocompatibility-complex","display_name":"major histocompatibility complex","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9313998818397522},{"id":"https://openalex.org/C2781470023","wikidata":"https://www.wikidata.org/wiki/Q74363","display_name":"Seahorse","level":2,"score":0.8799673318862915},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.7873826622962952},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.5314594507217407},{"id":"https://openalex.org/C193419808","wikidata":"https://www.wikidata.org/wiki/Q1645075","display_name":"Acquired immune system","level":3,"score":0.5047992467880249},{"id":"https://openalex.org/C136449434","wikidata":"https://www.wikidata.org/wiki/Q428253","display_name":"Innate immune system","level":3,"score":0.4595668613910675},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.4362732470035553},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3598811626434326},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.29972654581069946}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007109","descriptor_name":"Immunity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015870","descriptor_name":"Gene Expression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023701","descriptor_name":"Smegmamorpha","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.dci.2024.105136","doi":"https://doi.org/10.1016/j.dci.2024.105136","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.dci.2024.105136","pdf_url":null,"source":{"id":"https://openalex.org/S81563257","display_name":"Developmental & Comparative Immunology","issn_l":"0145-305X","issn":["0145-305X","1879-0089"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental & Comparative Immunology","raw_type":"journal-article"},{"id":"pmid:38185263","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38185263","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental and comparative immunology","raw_type":"Journal Article"},{"id":"pmh:oai:oceanrep.geomar.de:60052","doi":null,"is_oa":true,"landing_page_url":"https://orcid.org/0000-0003-1533-2430>,","pdf_url":"https://oceanrep.geomar.de/id/eprint/60052/1/1-s2.0-S0145305X24000089-main.pdf","source":{"id":"https://openalex.org/S4306400264","display_name":"Helmholtz Centre for Ocean Research Kiel (GEOMAR)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I34403800","host_organization_name":"GEOMAR Helmholtz Centre for Ocean Research Kiel","host_organization_lineage":["https://openalex.org/I34403800"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1016/j.dci.2024.105136","doi":"https://doi.org/10.1016/j.dci.2024.105136","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.dci.2024.105136","pdf_url":null,"source":{"id":"https://openalex.org/S81563257","display_name":"Developmental & Comparative Immunology","issn_l":"0145-305X","issn":["0145-305X","1879-0089"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-2","poland-140","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental & Comparative Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/14","display_name":"Life below water","score":1.0},{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[{"id":"https://openalex.org/G117416242","display_name":null,"funder_award_id":"RO 4628/3-3","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G1493288310","display_name":null,"funder_award_id":"RO 4628/3-1","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G27107548","display_name":null,"funder_award_id":"5822/1-2","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G2964454638","display_name":null,"funder_award_id":"RO-4628/4-2","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"},{"id":"https://openalex.org/G3901222481","display_name":"Male pregnancy \u2013 Unravelling the coevolution of parental investment and immune defence","funder_award_id":"755659","funder_id":"https://openalex.org/F4320338335","funder_display_name":"H2020 European Research Council"},{"id":"https://openalex.org/G4937468798","display_name":null,"funder_award_id":"H2020","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G6974185316","display_name":null,"funder_award_id":"WE 5822/1\\u20132","funder_id":"https://openalex.org/F4320320879","funder_display_name":"Deutsche Forschungsgemeinschaft"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320332999","display_name":"Horizon 2020 Framework Programme","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320334678","display_name":"European Research Council","ror":"https://ror.org/0472cxd90"},{"id":"https://openalex.org/F4320338335","display_name":"H2020 European Research Council","ror":"https://ror.org/0472cxd90"},{"id":"https://openalex.org/F4320338453","display_name":"HORIZON EUROPE European Research Council","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4390619633.pdf","grobid_xml":"https://content.openalex.org/works/W4390619633.grobid-xml"},"referenced_works_count":158,"referenced_works":["https://openalex.org/W27709151","https://openalex.org/W33755602","https://openalex.org/W170345446","https://openalex.org/W621968997","https://openalex.org/W1520839665","https://openalex.org/W1535141082","https://openalex.org/W1541589221","https://openalex.org/W1569062417","https://openalex.org/W1650996792","https://openalex.org/W1809465273","https://openalex.org/W1888531671","https://openalex.org/W1900937478","https://openalex.org/W1968191137","https://openalex.org/W1973208496","https://openalex.org/W1973265912","https://openalex.org/W1974508755","https://openalex.org/W1976527118","https://openalex.org/W1981667710","https://openalex.org/W1983417158","https://openalex.org/W1991024712","https://openalex.org/W1995423591","https://openalex.org/W1998562719","https://openalex.org/W2002706411","https://openalex.org/W2004465286","https://openalex.org/W2010371552","https://openalex.org/W2010902450","https://openalex.org/W2010980655","https://openalex.org/W2015821670","https://openalex.org/W2020777546","https://openalex.org/W2024015921","https://openalex.org/W2024261001","https://openalex.org/W2024875935","https://openalex.org/W2031794136","https://openalex.org/W2039031569","https://openalex.org/W2043064101","https://openalex.org/W2044757050","https://openalex.org/W2045079820","https://openalex.org/W2045204781","https://openalex.org/W2050703672","https://openalex.org/W2050926115","https://openalex.org/W2054538838","https://openalex.org/W2055724614","https://openalex.org/W2055735866","https://openalex.org/W2061041720","https://openalex.org/W2062382041","https://openalex.org/W2062674759","https://openalex.org/W2064112983","https://openalex.org/W2066527693","https://openalex.org/W2067031028","https://openalex.org/W2067263136","https://openalex.org/W2069559049","https://openalex.org/W2071037185","https://openalex.org/W2073621589","https://openalex.org/W2079308568","https://openalex.org/W2080097192","https://openalex.org/W2082620312","https://openalex.org/W2088191325","https://openalex.org/W2088657186","https://openalex.org/W2091987784","https://openalex.org/W2094092039","https://openalex.org/W2094199171","https://openalex.org/W2094381289","https://openalex.org/W2094637827","https://openalex.org/W2096428863","https://openalex.org/W2098994887","https://openalex.org/W2100788374","https://openalex.org/W2100895352","https://openalex.org/W2106909551","https://openalex.org/W2108456645","https://openalex.org/W2110065044","https://openalex.org/W2111542462","https://openalex.org/W2115710752","https://openalex.org/W2116144570","https://openalex.org/W2116797415","https://openalex.org/W2119512070","https://openalex.org/W2121941407","https://openalex.org/W2125349292","https://openalex.org/W2128337342","https://openalex.org/W2130133091","https://openalex.org/W2131937089","https://openalex.org/W2133271064","https://openalex.org/W2133956851","https://openalex.org/W2140876277","https://openalex.org/W2141120240","https://openalex.org/W2142495846","https://openalex.org/W2146313292","https://openalex.org/W2153228000","https://openalex.org/W2153307836","https://openalex.org/W2155356126","https://openalex.org/W2156293127","https://openalex.org/W2158217645","https://openalex.org/W2160378127","https://openalex.org/W2162562269","https://openalex.org/W2167450753","https://openalex.org/W2169456326","https://openalex.org/W2171457062","https://openalex.org/W2179438025","https://openalex.org/W2191302747","https://openalex.org/W2217062597","https://openalex.org/W2263856609","https://openalex.org/W2295965848","https://openalex.org/W2330561455","https://openalex.org/W2336656712","https://openalex.org/W2342855510","https://openalex.org/W2418443947","https://openalex.org/W2507252565","https://openalex.org/W2517883318","https://openalex.org/W2518240058","https://openalex.org/W2529181956","https://openalex.org/W2552643092","https://openalex.org/W2582743722","https://openalex.org/W2587569845","https://openalex.org/W2591986938","https://openalex.org/W2603958196","https://openalex.org/W2613048284","https://openalex.org/W2770449496","https://openalex.org/W2771264754","https://openalex.org/W2791156192","https://openalex.org/W2889118392","https://openalex.org/W2898299047","https://openalex.org/W2899250708","https://openalex.org/W2910994391","https://openalex.org/W2951829289","https://openalex.org/W2951912016","https://openalex.org/W2952148446","https://openalex.org/W2956255377","https://openalex.org/W2979841886","https://openalex.org/W2988396470","https://openalex.org/W3003210811","https://openalex.org/W3007135380","https://openalex.org/W3009920944","https://openalex.org/W3012226857","https://openalex.org/W3015968582","https://openalex.org/W3028228064","https://openalex.org/W3043187219","https://openalex.org/W3046299129","https://openalex.org/W3088531213","https://openalex.org/W3118519502","https://openalex.org/W3144118462","https://openalex.org/W3159082567","https://openalex.org/W3186493466","https://openalex.org/W3199180046","https://openalex.org/W3202997182","https://openalex.org/W4200163972","https://openalex.org/W4200615868","https://openalex.org/W4210248739","https://openalex.org/W4210556729","https://openalex.org/W4220777171","https://openalex.org/W4236842068","https://openalex.org/W4245248161","https://openalex.org/W4285494616","https://openalex.org/W4307425817","https://openalex.org/W4310917352","https://openalex.org/W4318046507","https://openalex.org/W4409233301","https://openalex.org/W6632436679","https://openalex.org/W6675086135","https://openalex.org/W6765290241"],"related_works":["https://openalex.org/W3217504528","https://openalex.org/W3163325991","https://openalex.org/W2116089822","https://openalex.org/W3186493466","https://openalex.org/W3180067474","https://openalex.org/W3094284564","https://openalex.org/W2263856609","https://openalex.org/W4404323327","https://openalex.org/W3214570620","https://openalex.org/W4417333131"],"abstract_inverted_index":{"Evolutionary":[0],"adaptations":[1],"in":[2,12,58,73,95,176,181,198,221,235,256],"the":[3,23,50,79,99,135,139,147,158,182,226],"Syngnathidae":[4],"teleost":[5],"family":[6],"(seahorses,":[7],"pipefish":[8],"and":[9,22,35,49,68,90],"seadragons)":[10],"culminated":[11],"an":[13,217],"array":[14],"of":[15,52,83,138,166,184,229],"spectacular":[16],"morphologies,":[17],"key":[18],"immune":[19,80,105,109,117,140,149,196,219,233],"gene":[20],"losses,":[21],"enigmatic":[24],"male":[25],"pregnancy.":[26],"In":[27,61],"seahorses,":[28,180],"genome":[29],"modifications":[30],"associated":[31,132],"with":[32,121,128,134],"immunoglobulins,":[33],"complement,":[34],"major":[36],"histocompatibility":[37],"complex":[38],"(MHC":[39],"II)":[40],"pathway":[41,186,248],"components":[42],"raise":[43],"questions":[44],"concerning":[45],"their":[46,59,154],"immunological":[47,155],"efficiency":[48],"evolution":[51],"compensatory":[53,262],"measures":[54],"that":[55],"may":[56],"act":[57],"place.":[60],"this":[62],"investigation":[63,224],"heat-killed":[64],"bacteria":[65,242],"(Vibrio":[66],"aestuarianus":[67,130],"Tenacibaculum":[69],"maritimum)":[70],"were":[71,93],"used":[72],"a":[74,114,189,260],"two-phased":[75],"experiment":[76],"to":[77,97,104,153,216,239],"assess":[78],"response":[81,118],"dynamics":[82],"Hippocampus":[84],"erectus.":[85],"Gill":[86],"transcriptomes":[87],"from":[88],"double":[89],"single-exposed":[91,122,125],"individuals":[92,112],"analysed":[94],"order":[96],"determine":[98],"differentially":[100],"expressed":[101],"genes":[102],"contributing":[103],"system":[106],"responses":[107,234],"towards":[108,157],"priming.":[110],"Double-exposed":[111],"exhibited":[113,146],"greater":[115],"adaptive":[116,218,232],"when":[119,237],"compared":[120],"individuals,":[123,126],"while":[124,160],"particularly":[127],"V.":[129,178],"replicates,":[131],"more":[133],"innate":[136,167,253],"branch":[137],"system.":[141],"T.":[142],"maritimum":[143],"double-exposed":[144],"replicates":[145],"strongest":[148],"reaction,":[150],"likely":[151],"due":[152],"naivety":[156],"bacterium,":[159],"there":[161],"are":[162],"also":[163],"potential":[164,261],"signs":[165],"trained":[168,254],"immunity.":[169],"MHC":[170,194,246],"II":[171,195,247],"upregulated":[172],"expression":[173],"was":[174],"identified":[175],"selected":[177],"aestuarianus-exposed":[179],"absence":[183],"other":[185],"constituents":[187],"suggesting":[188],"possible":[190],"alternative":[191],"or":[192],"non-classical":[193],"function":[197,249],"seahorses.":[199,222],"Gene":[200],"Ontology":[201],"(GO)":[202],"enrichment":[203],"analysis":[204],"highlighted":[205],"prominent":[206,227],"angiogenesis":[207],"activity":[208],"following":[209],"secondary":[210],"exposure,":[211],"which":[212],"could":[213,258],"be":[214,259],"linked":[215],"process":[220],"This":[223],"highlights":[225],"role":[228],"T-cell":[230],"mediated":[231],"seahorses":[236],"exposed":[238],"sequential":[240],"foreign":[241],"exposures.":[243],"If":[244],"classical":[245],"has":[250],"been":[251],"lost,":[252],"immunity":[255],"syngnathids":[257],"mechanism.":[263]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2024-01-07T00:00:00"}