{"id":"https://openalex.org/W4390594565","doi":"https://doi.org/10.18103/mra.v11i12.4953","title":"\"Revolutionizing Amyotrophic Lateral Sclerosis (ALS) Management: A Case Report on Muscle Regeneration and Sustained Relaxation through Placental Injection Therapy at Rodem Hospital\"","display_name":"\"Revolutionizing Amyotrophic Lateral Sclerosis (ALS) Management: A Case Report on Muscle Regeneration and Sustained Relaxation through Placental Injection Therapy at Rodem Hospital\"","publication_year":2023,"publication_date":"2023-12-26","ids":{"openalex":"https://openalex.org/W4390594565","doi":"https://doi.org/10.18103/mra.v11i12.4953"},"language":"en","primary_location":{"id":"doi:10.18103/mra.v11i12.4953","doi":"https://doi.org/10.18103/mra.v11i12.4953","is_oa":true,"landing_page_url":"http://dx.doi.org/10.18103/mra.v11i12.4953","pdf_url":null,"source":{"id":"https://openalex.org/S2764661345","display_name":"Medical Research Archives","issn_l":"2375-1916","issn":["2375-1916","2375-1924"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4376882788","host_organization_name":"European Society of Medicine","host_organization_lineage":["https://openalex.org/P4376882788"],"host_organization_lineage_names":["European Society of Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Research Archives","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://dx.doi.org/10.18103/mra.v11i12.4953","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067669266","display_name":"Jae-Kook Yoo","orcid":"https://orcid.org/0000-0003-2926-2445","observed_orcids":["https://orcid.org/0000-0003-2926-2445"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jae-kook Yoo","raw_affiliation_strings":["Department of Neurolgy, The Rodem Hospital, Incheon, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurolgy, The Rodem Hospital, Incheon, Korea","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017827270","display_name":"Soon-Hee Kwon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Soon-Hee Kwon","raw_affiliation_strings":["Department of Neurolgy, The Rodem Hospital, Incheon, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurolgy, The Rodem Hospital, Incheon, Korea","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103336950","display_name":"Jong-Eun Jeon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jong-Eun Jeon","raw_affiliation_strings":["Department of Neurolgy, The Rodem Hospital, Incheon, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurolgy, The Rodem Hospital, Incheon, Korea","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102601082","display_name":"Sul-Hee Yoon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sul-Hee Yoon","raw_affiliation_strings":["Department of Internal medicine, The Rodem Hospital, Incheon, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal medicine, The Rodem Hospital, Incheon, Korea","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100456880","display_name":"Jung-eun Lee","orcid":"https://orcid.org/0000-0003-0641-5269","observed_orcids":["https://orcid.org/0000-0003-0641-5269"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jung-Eun Lee","raw_affiliation_strings":["Department of Rehabilitation medicine, The Rodem Hospital, Incheon, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rehabilitation medicine, The Rodem Hospital, Incheon, Korea","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100416603","display_name":"Sangyoon Lee","orcid":"https://orcid.org/0000-0003-2595-505X","observed_orcids":["https://orcid.org/0000-0003-2595-505X","https://orcid.org/0000-0002-0749-7641"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sang-Yoon Lee","raw_affiliation_strings":["Department of Rehabilitation medicine, The Rodem Hospital, Incheon, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rehabilitation medicine, The Rodem Hospital, Incheon, Korea","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11","issue":"12","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9711999893188477,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11274","display_name":"Botulinum Toxin and Related Neurological Disorders","score":0.013500000350177288,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology and Disorders","score":0.00559999980032444,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amyotrophic-lateral-sclerosis","display_name":"amyotrophic lateral sclerosis","score":1.0},{"id":"https://openalex.org/keywords/muscle-rigidity","display_name":"muscle rigidity","score":0.9269999861717224},{"id":"https://openalex.org/keywords/lidocaine","display_name":"lidocaine","score":0.9890000224113464},{"id":"https://openalex.org/keywords/muscle-regeneration","display_name":"muscle regeneration","score":0.8560000061988831},{"id":"https://openalex.org/keywords/muscle-relaxation","display_name":"muscle relaxation","score":0.7639999985694885},{"id":"https://openalex.org/keywords/knee-flexion","display_name":"knee flexion","score":0.9810000061988831},{"id":"https://openalex.org/keywords/pain-relief","display_name":"analgesia","score":0.9629999995231628},{"id":"https://openalex.org/keywords/als-treatment","display_name":"ALS treatment","score":0.4000000059604645}],"concepts":[{"id":"https://openalex.org/C2780596555","wikidata":"https://www.wikidata.org/wiki/Q206901","display_name":"Amyotrophic lateral sclerosis","level":3,"score":0.8403738737106323},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7691527605056763},{"id":"https://openalex.org/C2780149897","wikidata":"https://www.wikidata.org/wiki/Q216935","display_name":"Lidocaine","level":2,"score":0.7529327273368835},{"id":"https://openalex.org/C2992204568","wikidata":"https://www.wikidata.org/wiki/Q127006","display_name":"Muscle relaxation","level":2,"score":0.44040369987487793},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.43930286169052124},{"id":"https://openalex.org/C1862650","wikidata":"https://www.wikidata.org/wiki/Q186005","display_name":"Physical therapy","level":1,"score":0.3487534523010254},{"id":"https://openalex.org/C99508421","wikidata":"https://www.wikidata.org/wiki/Q2678675","display_name":"Physical medicine and rehabilitation","level":1,"score":0.33097589015960693},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1949927806854248},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.19002509117126465}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.18103/mra.v11i12.4953","doi":"https://doi.org/10.18103/mra.v11i12.4953","is_oa":true,"landing_page_url":"http://dx.doi.org/10.18103/mra.v11i12.4953","pdf_url":null,"source":{"id":"https://openalex.org/S2764661345","display_name":"Medical Research Archives","issn_l":"2375-1916","issn":["2375-1916","2375-1924"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4376882788","host_organization_name":"European Society of Medicine","host_organization_lineage":["https://openalex.org/P4376882788"],"host_organization_lineage_names":["European Society of Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Research Archives","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.18103/mra.v11i12.4953","doi":"https://doi.org/10.18103/mra.v11i12.4953","is_oa":true,"landing_page_url":"http://dx.doi.org/10.18103/mra.v11i12.4953","pdf_url":null,"source":{"id":"https://openalex.org/S2764661345","display_name":"Medical Research Archives","issn_l":"2375-1916","issn":["2375-1916","2375-1924"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4376882788","host_organization_name":"European Society of Medicine","host_organization_lineage":["https://openalex.org/P4376882788"],"host_organization_lineage_names":["European Society of Medicine"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Research Archives","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4409908133","https://openalex.org/W7212030808","https://openalex.org/W2334729435","https://openalex.org/W4411902022","https://openalex.org/W2076039687","https://openalex.org/W2954694270","https://openalex.org/W2383387157","https://openalex.org/W7084496232","https://openalex.org/W2938705800","https://openalex.org/W7221588157"],"abstract_inverted_index":{"This":[0,32,101,124,150,182,251,274],"case":[1,125,151,275],"report":[2,152],"from":[3,153],"the":[4,79,128,154,229,278],"Rodem":[5,155],"Hospital":[6,156],"introduces":[7,157],"a":[8,20,53,64,89,117,158,170,203,214,239,267],"pioneering":[9,159],"intervention":[10,160],"for":[11,105,161,255],"muscle":[12,38,111,162,188,261],"rigidity":[13,163],"in":[14,43,85,92,121,137,164,193,235,242,271,287],"Amyotrophic":[15,165],"Lateral":[16,166],"Sclerosis":[17,167],"(ALS),":[18,168],"featuring":[19,169],"unique":[21,171],"placental":[22,70,172,220],"extract":[23,173],"injection":[24,27,174,177],"and":[25,40,56,69,88,113,133,147,175,190,206,219,238,263,283,297],"glucose":[26,176],"therapy":[28,178],"combined":[29,179],"with":[30,180],"lidocaine.":[31,181],"novel":[33,183],"approach":[34,184],"has":[35,185],"demonstrated":[36,186],"significant":[37,187],"regeneration":[39,189],"sustained":[41,191],"relaxation":[42,192],"47":[44,80,194,230],"ALS":[45,122,138,195,272,288],"patients.":[46,196],"Unlike":[47,197],"traditional":[48,198],"treatments,":[49,199],"this":[50,200],"protocol":[51,201],"offers":[52,202],"more":[54,204],"sustainable":[55,205],"regenerative":[57,207],"outcome.":[58,208],"The":[59,94,209,244],"treatment":[60,135,210,285],"involved":[61,211],"injections":[62,212],"of":[63,78,130,145,213,228,280,295],"mixture":[65,215],"containing":[66,216],"glucose,":[67,217],"lidocaine,":[68,218],"extract,":[71,221],"targeting":[72,222],"severely":[73,223],"rigid":[74,224],"muscles.":[75,225],"Remarkably,":[76,226],"42":[77,227],"patients":[81,231],"showed":[82,232],"considerable":[83,233],"improvements":[84,234],"knee":[86,236],"flexion":[87,237],"dramatic":[90,240],"reduction":[91,241],"pain.":[93,243],"other":[95,245],"two":[96,246],"also":[97,247],"experienced":[98,248],"notable":[99,249],"progress.":[100,250],"method":[102,252],"stands":[103,253],"out":[104,254],"its":[106,256],"cost":[107,257],"efficiency,":[108,258],"impact":[109,259],"on":[110,260],"suppleness,":[112,262],"reduced":[114,264],"pain,":[115,265],"suggesting":[116,266],"potential":[118,268],"paradigm":[119,269],"shift":[120,270],"management.":[123,273],"series":[126,276],"highlights":[127,277],"importance":[129,279],"continued":[131,281],"innovation":[132,282],"personalized":[134,284],"strategies":[136,286],"care,":[139,289],"aiming":[140,290],"to":[141,291],"improve":[142,292],"patient":[143,293],"quality":[144,294],"life":[146,296],"functional":[148,298],"abilities.":[149,299]},"counts_by_year":[],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2024-01-05T00:00:00"}