{"id":"https://openalex.org/W4390191960","doi":"https://doi.org/10.1002/alz.083216","title":"Using 7T MRI to study hippocampal structures in Alzheimer\u2019s disease and post\u2010SARS\u2010CoV2 infection","display_name":"Using 7T MRI to study hippocampal structures in Alzheimer\u2019s disease and post\u2010SARS\u2010CoV2 infection","publication_year":2023,"publication_date":"2023-12-01","ids":{"openalex":"https://openalex.org/W4390191960","doi":"https://doi.org/10.1002/alz.083216"},"language":"en","primary_location":{"id":"doi:10.1002/alz.083216","doi":"https://doi.org/10.1002/alz.083216","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1002/alz.083216","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.083216","source":{"id":"https://openalex.org/S108427512","display_name":"Alzheimer s & Dementia","issn_l":"1552-5260","issn":["1552-5260","1552-5279"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-3","ki-jl-3","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's & Dementia","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.083216","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038780154","display_name":"Akram A. Hosseini","orcid":"https://orcid.org/0000-0003-0133-9842","observed_orcids":["https://orcid.org/0000-0003-0133-9842"]},"institutions":[{"id":"https://openalex.org/I1334287468","display_name":"Nottingham University Hospitals NHS Trust","ror":"https://ror.org/05y3qh794","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1334287468"]},{"id":"https://openalex.org/I4210137227","display_name":"Queen's Medical Centre","ror":"https://ror.org/03ap6wx93","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I1334287468","https://openalex.org/I4210137227"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Akram A. Hosseini","raw_affiliation_strings":["Nottingham University Hospitals NHS Trust, Queens Medical Center, Nottingham, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nottingham University Hospitals NHS Trust, Queens Medical Center, Nottingham, United Kingdom","institution_ids":["https://openalex.org/I1334287468","https://openalex.org/I4210137227"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047941273","display_name":"Oluwatobi F Adeyemi","orcid":"https://orcid.org/0000-0001-9415-4112","observed_orcids":["https://orcid.org/0000-0001-9415-4112"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Oluwatobi F Adeyemi","raw_affiliation_strings":["Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom","institution_ids":["https://openalex.org/I142263535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086224910","display_name":"Richard W Bowtell","orcid":"https://orcid.org/0000-0001-8656-412X","observed_orcids":["https://orcid.org/0000-0001-8656-412X"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Richard Bowtell","raw_affiliation_strings":["Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom","institution_ids":["https://openalex.org/I142263535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085160808","display_name":"Penny Anne Gowland","orcid":"https://orcid.org/0000-0002-4900-4817","observed_orcids":["https://orcid.org/0000-0002-4900-4817"]},"institutions":[{"id":"https://openalex.org/I142263535","display_name":"University of Nottingham","ror":"https://ror.org/01ee9ar58","country_code":"GB","type":"education","lineage":["https://openalex.org/I142263535"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Gowland Penny","raw_affiliation_strings":["Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sir Peter Mansfield Imaging Centre, University of Nottingham, Nottingham, United Kingdom","institution_ids":["https://openalex.org/I142263535"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074729401","display_name":"Tamer S. Ibrahim","orcid":"https://orcid.org/0000-0001-6738-5855","observed_orcids":["https://orcid.org/0000-0001-6738-5855"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tamer Ibrahim","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059490394","display_name":"Jr\u2010Jiun Liou","orcid":"https://orcid.org/0000-0002-8800-9557","observed_orcids":["https://orcid.org/0000-0002-8800-9557"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jr\u2010Jiun Liou","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074796537","display_name":"Tales Santini","orcid":"https://orcid.org/0000-0003-4533-9190","observed_orcids":["https://orcid.org/0000-0003-4533-9190"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tales Santini","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040919805","display_name":"Jinghang Li","orcid":"https://orcid.org/0000-0003-1960-9839","observed_orcids":["https://orcid.org/0000-0003-1960-9839"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jinghang Li","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093577875","display_name":"Salem Alkateeb","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Salem Alkateeb","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019478049","display_name":"Mohamad Habes","orcid":"https://orcid.org/0000-0001-9447-5805","observed_orcids":["https://orcid.org/0000-0001-9447-5805"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohamad Habes","raw_affiliation_strings":["University of Texas Health San Antonio, San Antonio, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Texas Health San Antonio, San Antonio, TX, USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015065654","display_name":"Monica Goss","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Monica Goss","raw_affiliation_strings":["Glenn Biggs Institute for Alzheimer\u2019s & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, TX USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glenn Biggs Institute for Alzheimer\u2019s & Neurodegenerative Diseases, UT Health San Antonio, San Antonio, TX USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053331010","display_name":"Farhaan Vahidy","orcid":"https://orcid.org/0000-0002-3464-2111","observed_orcids":["https://orcid.org/0000-0002-3464-2111"]},"institutions":[{"id":"https://openalex.org/I4405286254","display_name":"Houston Methodist Research Institute","ror":"https://ror.org/01mcrxx35","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1295876152","https://openalex.org/I4405286254"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Farhaan S Vahidy","raw_affiliation_strings":["Houston Methodist Research Institute, Houston, TX, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Houston Methodist Research Institute, Houston, TX, USA","institution_ids":["https://openalex.org/I4405286254"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000291248","display_name":"Heidi I.L. Jacobs","orcid":"https://orcid.org/0000-0001-7620-3822","observed_orcids":["https://orcid.org/0000-0001-7620-3822"]},"institutions":[{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heidi I.L. Jacobs","raw_affiliation_strings":["Massachusetts General Hospital, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Massachusetts General Hospital, Boston, MA, USA","institution_ids":["https://openalex.org/I4210087915"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025056027","display_name":"Timothy D. Girard","orcid":"https://orcid.org/0000-0002-9833-4871","observed_orcids":["https://orcid.org/0000-0002-9833-4871"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy D. Girard","raw_affiliation_strings":["University of Pittsburgh, Pittsburgh, PA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh, Pittsburgh, PA, USA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016688715","display_name":"Gabriel A. de Erausquin","orcid":"https://orcid.org/0000-0001-6423-4461","observed_orcids":["https://orcid.org/0000-0001-6423-4461"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gabriel A. de Erausquin","raw_affiliation_strings":["Glenn Biggs Institute for Alzheimer\u2019s & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, TX USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glenn Biggs Institute for Alzheimer\u2019s & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, TX USA","institution_ids":["https://openalex.org/I165951966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001912833","display_name":"Heather M. Snyder","orcid":"https://orcid.org/0000-0002-7665-7696","observed_orcids":["https://orcid.org/0000-0002-7665-7696"]},"institutions":[{"id":"https://openalex.org/I1279571640","display_name":"Alzheimer's Association","ror":"https://ror.org/0375f4d26","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1279571640"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heather M Snyder","raw_affiliation_strings":["Alzheimer's Association, Chicago, IL, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Alzheimer's Association, Chicago, IL, USA","institution_ids":["https://openalex.org/I1279571640"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011863508","display_name":"Sudha S. Seshadri","orcid":"https://orcid.org/0000-0001-6135-2622","observed_orcids":["https://orcid.org/0000-0001-6135-2622"]},"institutions":[{"id":"https://openalex.org/I165951966","display_name":"The University of Texas at San Antonio Health Science Center","ror":"https://ror.org/02f6dcw23","country_code":"US","type":"education","lineage":["https://openalex.org/I165951966","https://openalex.org/I45438204"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sudha Seshadri","raw_affiliation_strings":["Glenn Biggs Institute for Alzheimer\u2019s & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, TX USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glenn Biggs Institute for Alzheimer\u2019s & Neurodegenerative Diseases, University of Texas Health Science Center, San Antonio, TX USA","institution_ids":["https://openalex.org/I165951966"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5038780154"],"corresponding_institution_ids":["https://openalex.org/I1334287468","https://openalex.org/I4210137227"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.4943,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.6043918,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"19","issue":"S24","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.9721999764442444,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11368","display_name":"Long-Term Effects of COVID-19","score":0.007600000128149986,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.006200000178068876,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.9810000061988831},{"id":"https://openalex.org/keywords/covid-19","display_name":"COVID-19 pandemic","score":0.8519999980926514}],"concepts":[{"id":"https://openalex.org/C148762608","wikidata":"https://www.wikidata.org/wiki/Q3748185","display_name":"Hippocampal formation","level":2,"score":0.6161753535270691},{"id":"https://openalex.org/C29022207","wikidata":"https://www.wikidata.org/wiki/Q7268943","display_name":"Quantitative susceptibility mapping","level":3,"score":0.609626293182373},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.6027630567550659},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6020106077194214},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.49548208713531494},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.4890080392360687},{"id":"https://openalex.org/C2777790613","wikidata":"https://www.wikidata.org/wiki/Q191562","display_name":"Cerebral amyloid angiopathy","level":4,"score":0.4658169746398926},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42373281717300415},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3828543722629547},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.37477797269821167},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.32561376690864563},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.18852627277374268},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/alz.083216","doi":"https://doi.org/10.1002/alz.083216","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1002/alz.083216","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.083216","source":{"id":"https://openalex.org/S108427512","display_name":"Alzheimer s & Dementia","issn_l":"1552-5260","issn":["1552-5260","1552-5279"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-3","ki-jl-3","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's & Dementia","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1002/alz.083216","doi":"https://doi.org/10.1002/alz.083216","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1002/alz.083216","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/alz.083216","source":{"id":"https://openalex.org/S108427512","display_name":"Alzheimer s & Dementia","issn_l":"1552-5260","issn":["1552-5260","1552-5279"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-3","ki-jl-3","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's & Dementia","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G6918421256","display_name":"Brain Iron Toxicity and Neurodegeneration - MRI study at 7T","funder_award_id":"MR/T005580/1","funder_id":"https://openalex.org/F4320334626","funder_display_name":"Medical Research Council"}],"funders":[{"id":"https://openalex.org/F4320334626","display_name":"Medical Research Council","ror":"https://ror.org/03x94j517"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4390191960.pdf","grobid_xml":"https://content.openalex.org/works/W4390191960.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7116885894","https://openalex.org/W4206046812","https://openalex.org/W7116908797","https://openalex.org/W3198938269","https://openalex.org/W4390200874","https://openalex.org/W4414234939","https://openalex.org/W4416083450","https://openalex.org/W4404405644","https://openalex.org/W4390194920","https://openalex.org/W4415363200"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"7T":[2,120],"MRI":[3],"allows":[4],"implementation":[5],"of":[6,50,53,190,238,327,336,359],"high\u2010resolution":[7],"quantitative":[8],"susceptibility":[9,48,153,203,237,272,298],"mapping":[10],"(QSM)":[11],"which":[12],"can":[13],"be":[14,37,280],"used":[15,168,179],"to":[16,32,151,169,261,279,293],"assess":[17],"the":[18,29,98,123,129,140,171,185,191,205,219,236,239,243,252,274,286,300],"cerebral":[19,315],"microvascular/hypoperfusion":[20],"pathogenic":[21],"hypothesis":[22],"in":[23,28,39,42,58,180,202,242,251,273,285,304,320,329,338,342,345],"Alzheimer\u2019s":[24],"disease":[25],"(AD)":[26],"and":[27,82,101,135,159,188,194,210,306,348],"post\u2010SARS\u2010CoV2":[30],"setting":[31],"explore":[33],"if":[34],"there":[35,213,230,266],"may":[36,309],"similarities":[38],"brain":[40],"changes":[41,341],"these":[43],"two":[44],"conditions.":[45],"The":[46,296,331],"magnetic":[47],"(reflective":[49],"tissue":[51],"iron)":[52],"hippocampal":[54,172,301,343],"subfields":[55,173,344],"was":[56,199,214,231,267],"assessed":[57],"patients":[59,109,308],"with":[60,75,110,122],"1)":[61],"CSF\u2010Amyloid\u00df\u2010status":[62],"AD;":[63],"2)":[64],"mild":[65],"COVID\u201019":[66,74],"over":[67],"6":[68],"months":[69,79],"previously":[70,80],"(Cv);":[71],"3)":[72],"severe":[73],"ICU":[76],"admission":[77],">6":[78],"(ICU\u2010Cv);":[81],"4)":[83],"age\u2010matched":[84],"healthy":[85],"controls":[86],"(HC).":[87],"Methods":[88],"33":[89],"participants":[90,103],"(10":[91],"HC,":[92,211],"14":[93],"Cv,":[94,192],"9":[95],"ICU\u2010Cv)":[96],"for":[97,128,139,182,204,218],"COVID":[99,228],"study":[100,332],"24":[102],"(14":[104],"AD,":[105],"11HC)":[106],"from":[107,314,325],"AD":[108,130,195,209,305,321,347],"confirmed":[111],"CSF\u2010Amyloid\u00df":[112],"levels,":[113],"aged":[114],"42\u201079,":[115],"were":[116,147,167,178],"scanned":[117],"on":[118],"a":[119,215,232,268],"scanner":[121],"following":[124],"protocol":[125],"T2*":[126,136],"GRE":[127,138],"groups":[131,142],"(0.7\u00d70.7\u00d70.7mm3,TE/TR":[132],"=":[133,144,157,164,223,247,256,290],"20/31ms)":[134],"multi\u2010echo":[137],"Cv":[141,253],"(0.38\u00d70.38\u00d70.75mm3,TE1/TE2/TR":[143],"8.2/18.4/24ms).":[145],"Data":[146],"processed":[148],"using":[149],"QSMbox1":[150],"produce":[152],"maps.":[154],"PSIR":[155],"(0.55\u00d70.55\u00d70.55mm3,TE/TR":[156],"3.1/6.9ms)":[158],"T2\u2010weighted":[160],"FSE":[161],"(0.38\u00d70.39\u00d71.5mm3,":[162],"TE/TR":[163],"117/5900ms)":[165],"images":[166],"segment":[170],"(Figure":[174],"1)2.":[175],"One\u2010way":[176],"analyses":[177,265],"SPSS":[181],"comparison":[183],"between":[184,208,235],"HC":[186],"group":[187,245,254,288],"each":[189],"ICU\u2010Cv,":[193],"groups.":[196],"Results":[197],"There":[198],"no":[200],"change":[201],"whole":[206,240],"hippocampus":[207,241],"but":[212,249],"significant":[216,233],"difference":[217,234],"DG":[220],"subfield":[221,264],"(p":[222,246,255,289],"0.045),":[224],"Figure":[225,258],"2.":[226,366],"For":[227],"patients,":[229],"ICU\u2010Cv":[244,287,307],"0.035),":[248],"not":[250],"0.788),":[257],"3,":[259],"compared":[260,292],"HC.":[262,294],"In":[263],"trend":[269],"towards":[270],"decreased":[271],"subiculum,":[275],"an":[276],"area":[277],"known":[278],"affected":[281],"by":[282],"Alzheimer":[283],"pathology,":[284],"0.032)":[291],"Conclusion":[295],"lower":[297],"within":[299],"structures":[302],"observed":[303],"reflect":[310],"less":[311],"iron":[312],"either":[313],"hypoperfusion":[316],"or":[317,322],"vascular":[318],"injuries":[319],"additionally":[323],"result":[324],"sequelae":[326],"hypoxaemia":[328],"ICU\u2010Cv.":[330],"provides":[333],"preliminary":[334],"evidence":[335],"detectable":[337],"vivo":[339],"microstructural":[340],"both":[346],"post\u2010COVID":[349],"settings.":[350],"Funding:":[351],"Medical":[352],"Research":[353],"Council,":[354],"UK":[355],"(MR/T005580/1);":[356],"National":[357],"Institute":[358],"Health,":[360],"USA":[361],"(1R56AG074467\u201001)":[362],"References:":[363],"1.":[364],"https://doi.org/10.1016/j.neuroimage.2018.07.065":[365],"https://doi.org/10.1002/hbm.22627":[367]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2024,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2023-12-26T00:00:00"}