{"id":"https://openalex.org/W4390109733","doi":"https://doi.org/10.1111/trf.17690","title":"Reevaluation of the medical necessity of washed red blood cell transfusion in chronically transfused adults","display_name":"Reevaluation of the medical necessity of washed red blood cell transfusion in chronically transfused adults","publication_year":2023,"publication_date":"2023-12-21","ids":{"openalex":"https://openalex.org/W4390109733","doi":"https://doi.org/10.1111/trf.17690","pmid":"https://pubmed.ncbi.nlm.nih.gov/38130071"},"language":"en","primary_location":{"id":"doi:10.1111/trf.17690","doi":"https://doi.org/10.1111/trf.17690","is_oa":true,"landing_page_url":"https://doi.org/10.1111/trf.17690","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/trf.17690","source":{"id":"https://openalex.org/S186746772","display_name":"Transfusion","issn_l":"0041-1132","issn":["0041-1132","0372-1248","1537-2995","1878-2000"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transfusion","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/trf.17690","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076671376","display_name":"Tait H Huso","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tait Huso","raw_affiliation_strings":["Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055146594","display_name":"Kristen R. Buban","orcid":"https://orcid.org/0009-0005-5296-4981","observed_orcids":["https://orcid.org/0009-0005-5296-4981"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kristen Buban","raw_affiliation_strings":["Division of Transfusion Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA"],"raw_orcid":"https://orcid.org/0009-0005-5296-4981","affiliations":[{"raw_affiliation_string":"Division of Transfusion Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033877047","display_name":"Tayler A. Van Denakker","orcid":"https://orcid.org/0009-0006-4265-1559","observed_orcids":["https://orcid.org/0009-0006-4265-1559"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I98704320","display_name":"Icahn School of Medicine at Mount Sinai","ror":"https://ror.org/04a9tmd77","country_code":"US","type":"education","lineage":["https://openalex.org/I1320796813","https://openalex.org/I98704320"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tayler A. Van Denakker","raw_affiliation_strings":["Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA","Department of Pathology and Laboratory Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I145311948"]},{"raw_affiliation_string":"Department of Pathology and Laboratory Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA","institution_ids":["https://openalex.org/I98704320"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034026126","display_name":"Kathy Haddaway","orcid":"https://orcid.org/0009-0003-7636-1187","observed_orcids":["https://orcid.org/0009-0003-7636-1187"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kathy Haddaway","raw_affiliation_strings":["Division of Transfusion Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Transfusion Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077581848","display_name":"Heather Smetana","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heather Smetana","raw_affiliation_strings":["Division of Transfusion Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Transfusion Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113889978","display_name":"Christi E. Marshall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]},{"id":"https://openalex.org/I4210150714","display_name":"Johns Hopkins Hospital","ror":"https://ror.org/05cb1k848","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799853436","https://openalex.org/I4210150714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christi Marshall","raw_affiliation_strings":["Division of Transfusion Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Transfusion Medicine, Johns Hopkins Hospital, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I145311948","https://openalex.org/I4210150714"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012981458","display_name":"Herleen Rai","orcid":"https://orcid.org/0000-0001-6072-6098","observed_orcids":["https://orcid.org/0000-0001-6072-6098"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Herleen Rai","raw_affiliation_strings":["Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112185905","display_name":"Paul M. Ness","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul M. Ness","raw_affiliation_strings":["Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025869235","display_name":"Evan M. Bloch","orcid":"https://orcid.org/0000-0001-8181-9517","observed_orcids":["https://orcid.org/0000-0001-8181-9517"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Evan M. Bloch","raw_affiliation_strings":["Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"],"raw_orcid":"https://orcid.org/0000-0001-8181-9517","affiliations":[{"raw_affiliation_string":"Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066564090","display_name":"Aaron A.R. Tobian","orcid":"https://orcid.org/0000-0002-0517-3766","observed_orcids":["https://orcid.org/0000-0002-0517-3766"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron A. R. Tobian","raw_affiliation_strings":["Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"],"raw_orcid":"https://orcid.org/0000-0002-0517-3766","affiliations":[{"raw_affiliation_string":"Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I145311948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048080949","display_name":"Elizabeth P. Crowe","orcid":"https://orcid.org/0000-0003-1910-2800","observed_orcids":["https://orcid.org/0000-0003-1910-2800"]},"institutions":[{"id":"https://openalex.org/I145311948","display_name":"Johns Hopkins University","ror":"https://ror.org/00za53h95","country_code":"US","type":"education","lineage":["https://openalex.org/I145311948"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Elizabeth P. Crowe","raw_affiliation_strings":["Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA"],"raw_orcid":"https://orcid.org/0000-0003-1910-2800","affiliations":[{"raw_affiliation_string":"Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA","institution_ids":["https://openalex.org/I145311948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5048080949"],"corresponding_institution_ids":["https://openalex.org/I145311948"],"apc_list":{"value":3900,"currency":"USD","value_usd":3900},"apc_paid":null,"fwci":0.1449,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.47515528,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":"64","issue":"2","first_page":"216","last_page":"222"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12735","display_name":"Blood donation and transfusion practices","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1405","display_name":"Management of Technology and Innovation"},"field":{"id":"https://openalex.org/fields/14","display_name":"Business, Management and Accounting"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/washed-red-blood-cells","display_name":"washed red blood cells","score":0.8849999904632568},{"id":"https://openalex.org/keywords/red-blood-cell-washing","display_name":"red blood cell washing","score":0.7919999957084656},{"id":"https://openalex.org/keywords/allergic-transfusion-reaction","display_name":"allergic transfusion reaction","score":0.8619999885559082},{"id":"https://openalex.org/keywords/chronic-transfusion-therapy","display_name":"chronic transfusion","score":0.8309999704360962},{"id":"https://openalex.org/keywords/transfusion-costs","display_name":"transfusion costs","score":0.4569999873638153},{"id":"https://openalex.org/keywords/pruritus","display_name":"pruritus","score":0.7429999709129333},{"id":"https://openalex.org/keywords/transfusion-safety","display_name":"transfusion safety","score":0.6489999890327454}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7364166975021362},{"id":"https://openalex.org/C2911063046","wikidata":"https://www.wikidata.org/wiki/Q183605","display_name":"Red Blood Cell Transfusion","level":3,"score":0.6152583360671997},{"id":"https://openalex.org/C2780014101","wikidata":"https://www.wikidata.org/wiki/Q183605","display_name":"Blood transfusion","level":2,"score":0.598625659942627},{"id":"https://openalex.org/C2776557347","wikidata":"https://www.wikidata.org/wiki/Q37187","display_name":"Red blood cell","level":2,"score":0.5091187357902527},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4649661183357239},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2375059723854065}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004912","descriptor_name":"Erythrocytes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011537","descriptor_name":"Pruritus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017707","descriptor_name":"Erythrocyte Transfusion","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065227","descriptor_name":"Transfusion Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/trf.17690","doi":"https://doi.org/10.1111/trf.17690","is_oa":true,"landing_page_url":"https://doi.org/10.1111/trf.17690","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/trf.17690","source":{"id":"https://openalex.org/S186746772","display_name":"Transfusion","issn_l":"0041-1132","issn":["0041-1132","0372-1248","1537-2995","1878-2000"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transfusion","raw_type":"journal-article"},{"id":"pmid:38130071","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38130071","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transfusion","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/trf.17690","doi":"https://doi.org/10.1111/trf.17690","is_oa":true,"landing_page_url":"https://doi.org/10.1111/trf.17690","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/trf.17690","source":{"id":"https://openalex.org/S186746772","display_name":"Transfusion","issn_l":"0041-1132","issn":["0041-1132","0372-1248","1537-2995","1878-2000"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transfusion","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4390109733.pdf","grobid_xml":"https://content.openalex.org/works/W4390109733.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W1481244142","https://openalex.org/W1512818719","https://openalex.org/W1544004233","https://openalex.org/W1666649732","https://openalex.org/W1826156929","https://openalex.org/W1844606904","https://openalex.org/W1976965772","https://openalex.org/W2002425546","https://openalex.org/W2068366672","https://openalex.org/W2078408849","https://openalex.org/W2111006543","https://openalex.org/W2112154893","https://openalex.org/W2116031612","https://openalex.org/W2122863752","https://openalex.org/W2132271097","https://openalex.org/W2169166261","https://openalex.org/W2339233857","https://openalex.org/W2794338242","https://openalex.org/W2916695386","https://openalex.org/W2918195437","https://openalex.org/W2972178593","https://openalex.org/W2982313248","https://openalex.org/W3041621193","https://openalex.org/W3165329193","https://openalex.org/W4313646719","https://openalex.org/W4367052045"],"related_works":["https://openalex.org/W2068366672","https://openalex.org/W2381913372","https://openalex.org/W7154941529","https://openalex.org/W2411438426","https://openalex.org/W2330245979","https://openalex.org/W2515628087","https://openalex.org/W2618774831","https://openalex.org/W2014905268","https://openalex.org/W2129521098","https://openalex.org/W2042458126"],"abstract_inverted_index":{"BACKGROUND:":[0],"Washing":[1,221,237],"red":[2],"blood":[3],"cell":[4,32],"(RBC)":[5],"units":[6,143,198],"mitigates":[7],"severe":[8],"allergic":[9,81,159],"transfusion":[10,82,95,164],"reactions.":[11,160],"However,":[12],"washing":[13,24,101],"reduces":[14],"the":[15,20,104,107,192],"time":[16],"to":[17,48,77,243],"expiration":[18],"and":[19,27,94,111,178,213,248],"effective":[21],"dose.":[22],"Automated":[23],"is":[25],"time-":[26],"labor-intensive.":[28],"A":[29,55],"shortage":[30],"of":[31,38,80,85,106,139,176,195,222,235,246],"processor":[33],"tubing":[34,108],"sets":[35],"prompted":[36],"review":[37],"medical":[39],"necessity":[40,247],"for":[41,44,74,156],"washed":[42,141,188,196],"RBC":[43,62,142,197,218],"patients":[45,70,117,132,231],"previously":[46],"thought":[47],"require":[49],"washing.":[50],"STUDY":[51],"DESIGN":[52],"AND":[53],"METHODS:":[54],"single-center,":[56],"retrospective":[57],"study":[58],"investigated":[59],"discontinuing":[60],"wash":[61],"protocols":[63],"in":[64,228],"chronically":[65,229],"transfused":[66,135,230],"adults.":[67],"In":[68],"select":[69],"with":[71,136,166,173,180,187],"prior":[72],"requirements":[73],"washing,":[75],"due":[76,242],"a":[78,137,233],"history":[79,234],"reactions,":[83],"trials":[84],"unwashed":[86,167],"transfusions":[87],"were":[88,97,129,162],"performed.":[89],"Patient":[90],"demographic,":[91],"clinical,":[92],"laboratory,":[93],"data":[96],"compiled.":[98],"The":[99],"per-unit":[100],"cost":[102],"was":[103,184],"sum":[105],"set,":[109],"saline,":[110],"technical":[112],"labor":[113],"costs.":[114],"RESULTS:":[115],"Fifteen":[116],"(median":[118],"age":[119],"34":[120],"years":[121,150],"interquartile":[122],"range":[123],"[IQR]":[124],"23-53":[125],"years,":[126],"46.7%":[127],"female)":[128],"evaluated.":[130],"These":[131],"had":[133],"been":[134],"median":[138],"531":[140],"(IQR":[144,151],"244-1066)":[145],"per":[146,199,217],"patient":[147,172],"over":[148],"12":[149],"5-18":[152],"years),":[153],"most":[154],"commonly":[155],"recurrent,":[157],"non-severe":[158],"There":[161],"no":[163],"reactions":[165],"RBCs":[168,223],"aside":[169],"from":[170],"one":[171,174],"episode":[175],"pruritus":[177],"another":[179],"recurrent":[181],"pruritus,":[182],"which":[183],"typical":[185],"even":[186],"RBC.":[189],"We":[190],"decreased":[191],"mean":[193],"number":[194],"month":[200],"by":[201],"72.9%":[202],"(104":[203],"\u00b1":[204,208],"10":[205],"vs.":[206],"28.2":[207],"25.2;":[209],"p":[210],"<":[211],".0001)":[212],"saved":[214],"US":[215],"$100.25":[216],"unit.":[219],"CONCLUSION:":[220],"may":[224],"be":[225,239],"safely":[226],"reconsidered":[227],"without":[232],"anaphylaxis.":[236],"should":[238],"implemented":[240],"judiciously":[241],"potential":[244],"lack":[245],"logistical/operational":[249],"challenges.":[250]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-12-23T00:00:00"}