{"id":"https://openalex.org/W4390096512","doi":"https://doi.org/10.1002/9783527834266.ch40","title":"pH Sensor Designed for Cancer Cell Discrimination","display_name":"pH Sensor Designed for Cancer Cell Discrimination","publication_year":2023,"publication_date":"2023-12-22","ids":{"openalex":"https://openalex.org/W4390096512","doi":"https://doi.org/10.1002/9783527834266.ch40"},"language":"en","primary_location":{"id":"doi:10.1002/9783527834266.ch40","doi":"https://doi.org/10.1002/9783527834266.ch40","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1002/9783527834266.ch40","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/9783527834266.ch40","source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic and Inorganic Materials Based Sensors","raw_type":"other"},"volume":{"id":"https://openalex.org/W4390096278","display_name":"Organic and Inorganic Materials Based Sensors"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/9783527834266.ch40","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5045220816","display_name":"Sudhakar Pola","orcid":"https://orcid.org/0000-0002-6481-6493","observed_orcids":["https://orcid.org/0000-0002-6481-6493"]},"institutions":[{"id":"https://openalex.org/I100887729","display_name":"Andhra University","ror":"https://ror.org/049skhf47","country_code":"IN","type":"education","lineage":["https://openalex.org/I100887729"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Sudhakar Pola","raw_affiliation_strings":["Andhra University, Department of Biotechnology, Visakhapatnam, \n530003 \nIndia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Andhra University, Department of Biotechnology, Visakhapatnam, \n530003 \nIndia","institution_ids":["https://openalex.org/I100887729"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039282354","display_name":"DhanaLakshmi Padi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I100887729","display_name":"Andhra University","ror":"https://ror.org/049skhf47","country_code":"IN","type":"education","lineage":["https://openalex.org/I100887729"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Dhanalakshmi Padi,","raw_affiliation_strings":["Andhra University, Department of Biotechnology, Visakhapatnam, \n530003 \nIndia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Andhra University, Department of Biotechnology, Visakhapatnam, \n530003 \nIndia","institution_ids":["https://openalex.org/I100887729"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033672051","display_name":"Pavani Sanapala","orcid":"https://orcid.org/0000-0002-4084-9258","observed_orcids":["https://orcid.org/0000-0002-4084-9258"]},"institutions":[{"id":"https://openalex.org/I100887729","display_name":"Andhra University","ror":"https://ror.org/049skhf47","country_code":"IN","type":"education","lineage":["https://openalex.org/I100887729"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pavani Sanapala","raw_affiliation_strings":["Andhra University, Department of Biotechnology, Visakhapatnam, \n530003 \nIndia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Andhra University, Department of Biotechnology, Visakhapatnam, \n530003 \nIndia","institution_ids":["https://openalex.org/I100887729"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I100887729"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"933","last_page":"945"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.6538000106811523,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11472","display_name":"Analytical Chemistry and Sensors","score":0.6538000106811523,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection","score":0.33570000529289246,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ph-sensor","display_name":"pH sensor","score":0.6489999890327454},{"id":"https://openalex.org/keywords/tumor-cell-detection","display_name":"cancer cell detection","score":0.8309999704360962},{"id":"https://openalex.org/keywords/intracellular-ph","display_name":"intracellular pH","score":0.8840000033378601},{"id":"https://openalex.org/keywords/fluorescent-probes","display_name":"fluorescent probes","score":0.5929999947547913},{"id":"https://openalex.org/keywords/functionalized-nanoparticles","display_name":"functionalized nanoparticles","score":0.8960000276565552},{"id":"https://openalex.org/keywords/optical-chemical-sensors","display_name":"optical chemical sensors","score":0.722000002861023},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.8119999766349792}],"concepts":[{"id":"https://openalex.org/C134897140","wikidata":"https://www.wikidata.org/wiki/Q6058355","display_name":"Intracellular pH","level":3,"score":0.7389336824417114},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.6070458889007568},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.5952324867248535},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.5837433934211731},{"id":"https://openalex.org/C20251656","wikidata":"https://www.wikidata.org/wiki/Q162643","display_name":"Glycolysis","level":3,"score":0.5831762552261353},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5182811617851257},{"id":"https://openalex.org/C2994212657","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Cellular metabolism","level":3,"score":0.5132277011871338},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5011398792266846},{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.4792742431163788},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4227117598056793},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3920838236808777},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3882600963115692},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3593951165676117},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.30919504165649414},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26256221532821655},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.20395606756210327},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.11755549907684326},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/9783527834266.ch40","doi":"https://doi.org/10.1002/9783527834266.ch40","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1002/9783527834266.ch40","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/9783527834266.ch40","source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic and Inorganic Materials Based Sensors","raw_type":"other"}],"best_oa_location":{"id":"doi:10.1002/9783527834266.ch40","doi":"https://doi.org/10.1002/9783527834266.ch40","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1002/9783527834266.ch40","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/9783527834266.ch40","source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic and Inorganic Materials Based Sensors","raw_type":"other"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4390096512.pdf","grobid_xml":"https://content.openalex.org/works/W4390096512.grobid-xml"},"referenced_works_count":79,"referenced_works":["https://openalex.org/W1776216059","https://openalex.org/W1966948996","https://openalex.org/W1967652154","https://openalex.org/W1970044023","https://openalex.org/W1970838453","https://openalex.org/W1974426969","https://openalex.org/W1975192190","https://openalex.org/W1975219840","https://openalex.org/W1975385343","https://openalex.org/W1975684366","https://openalex.org/W1981322588","https://openalex.org/W1985041802","https://openalex.org/W1986567304","https://openalex.org/W1995998565","https://openalex.org/W2005496979","https://openalex.org/W2009278211","https://openalex.org/W2012685813","https://openalex.org/W2015015493","https://openalex.org/W2026227022","https://openalex.org/W2030539241","https://openalex.org/W2036429957","https://openalex.org/W2038684706","https://openalex.org/W2048722243","https://openalex.org/W2049098357","https://openalex.org/W2053044596","https://openalex.org/W2053058794","https://openalex.org/W2053343600","https://openalex.org/W2054795436","https://openalex.org/W2058922582","https://openalex.org/W2061475773","https://openalex.org/W2065376967","https://openalex.org/W2067010102","https://openalex.org/W2067127207","https://openalex.org/W2068050569","https://openalex.org/W2070802503","https://openalex.org/W2071807850","https://openalex.org/W2072799906","https://openalex.org/W2072868673","https://openalex.org/W2074602632","https://openalex.org/W2074747886","https://openalex.org/W2076153705","https://openalex.org/W2079816993","https://openalex.org/W2085652651","https://openalex.org/W2087581357","https://openalex.org/W2090391132","https://openalex.org/W2092861748","https://openalex.org/W2095178387","https://openalex.org/W2095893897","https://openalex.org/W2106769519","https://openalex.org/W2107327867","https://openalex.org/W2111988302","https://openalex.org/W2118838741","https://openalex.org/W2121990753","https://openalex.org/W2130503287","https://openalex.org/W2132482076","https://openalex.org/W2144648128","https://openalex.org/W2153255359","https://openalex.org/W2158571388","https://openalex.org/W2168301029","https://openalex.org/W2191594866","https://openalex.org/W2231330441","https://openalex.org/W2282518039","https://openalex.org/W2295771845","https://openalex.org/W2313698948","https://openalex.org/W2315988575","https://openalex.org/W2317588747","https://openalex.org/W2321291727","https://openalex.org/W2327407167","https://openalex.org/W2329379252","https://openalex.org/W2331698751","https://openalex.org/W2405950116","https://openalex.org/W2482728643","https://openalex.org/W2522989562","https://openalex.org/W2529267651","https://openalex.org/W2899958871","https://openalex.org/W3082555187","https://openalex.org/W3162099068","https://openalex.org/W4238605098","https://openalex.org/W4255555529"],"related_works":["https://openalex.org/W2610185769","https://openalex.org/W2976897583","https://openalex.org/W3011351757","https://openalex.org/W4412065199","https://openalex.org/W2808061543","https://openalex.org/W3113121136","https://openalex.org/W4238829047","https://openalex.org/W7126759118","https://openalex.org/W3015024750","https://openalex.org/W3016416008"],"abstract_inverted_index":{"The":[0,40],"detection":[1,23],"of":[2,24,78,120],"cancerous":[3],"cells":[4],"can":[5],"be":[6,98],"possible":[7],"by":[8],"single-cell":[9],"pH":[10,15,38,42,48,69,86,114],"sensing":[11],"and":[12,29,57,65,111,129],"the":[13,21,25,36,66,85,92,112,118],"intracellular":[14],"plays":[16],"a":[17,76],"significant":[18],"role":[19],"in":[20,62,81],"accurate":[22],"cancer":[26],"cells.":[27],"Fluorescence":[28],"functionalized":[30],"nanoparticle":[31],"probes":[32],"are":[33,45,50,95],"developed":[34],"for":[35,53,75],"single":[37],"sensing.":[39],"visual":[41],"sensors":[43,49],"that":[44],"optical":[46],"chemical":[47],"very":[51],"useful":[52],"analytical":[54],"real-time":[55],"devices":[56],"they":[58],"have":[59],"many":[60],"applications":[61],"medicine,":[63],"biology,":[64],"environment.":[67],"Physiological":[68],"level":[70],"is":[71,108],"an":[72],"important":[73],"marker":[74],"variety":[77],"biological":[79],"activities":[80],"human":[82],"tissues.":[83],"When":[84],"significantly":[87],"swerves":[88],"from":[89],"this":[90],"value,":[91],"cellular":[93,131],"functions":[94],"likely":[96],"to":[97,117,123],"affected.":[99],"In":[100],"diseased":[101],"tissues,":[102],"such":[103],"as":[104],"tumor,":[105],"its":[106],"microenvironment":[107],"typically":[109],"acidic":[110],"confined":[113],"values":[115],"change":[116],"range":[119],"5.5\u20137.0":[121],"due":[122],"their":[124],"inadequate":[125],"blood":[126],"perfusion,":[127],"hypoxia,":[128],"glycolytic":[130],"metabolism.":[132]},"counts_by_year":[],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2023-12-23T00:00:00"}