{"id":"https://openalex.org/W4389980628","doi":"https://doi.org/10.1016/j.jddst.2023.105291","title":"Nanocrystals loaded collagen/alginate-based injectable hydrogels: A promising biomaterial for bioavailability improvement of hydrophobic drugs","display_name":"Nanocrystals loaded collagen/alginate-based injectable hydrogels: A promising biomaterial for bioavailability improvement of hydrophobic drugs","publication_year":2023,"publication_date":"2023-12-19","ids":{"openalex":"https://openalex.org/W4389980628","doi":"https://doi.org/10.1016/j.jddst.2023.105291"},"language":"en","primary_location":{"id":"doi:10.1016/j.jddst.2023.105291","doi":"https://doi.org/10.1016/j.jddst.2023.105291","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jddst.2023.105291","pdf_url":null,"source":{"id":"https://openalex.org/S97205441","display_name":"Journal of Drug Delivery Science and Technology","issn_l":"1773-2247","issn":["1773-2247","2588-8943"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Delivery Science and Technology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W4389980628"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087063784","display_name":"Nazish Jabeen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16076960","display_name":"COMSATS University Islamabad","ror":"https://ror.org/00nqqvk19","country_code":"PK","type":"education","lineage":["https://openalex.org/I16076960"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Nazish Jabeen","raw_affiliation_strings":["Department of Pharmacy, COMSATS University, Islamabad, Abbottabad Campus, 22010, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, COMSATS University, Islamabad, Abbottabad Campus, 22010, Pakistan","institution_ids":["https://openalex.org/I16076960"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101678546","display_name":"Muhammad Farhan Sohail","orcid":"https://orcid.org/0000-0003-3596-1760","observed_orcids":["https://orcid.org/0000-0003-3596-1760"]},"institutions":[{"id":"https://openalex.org/I16076960","display_name":"COMSATS University Islamabad","ror":"https://ror.org/00nqqvk19","country_code":"PK","type":"education","lineage":["https://openalex.org/I16076960"]},{"id":"https://openalex.org/I16197041","display_name":"Cyprus International University","ror":"https://ror.org/04mk5mk38","country_code":"CY","type":"education","lineage":["https://openalex.org/I16197041"]}],"countries":["CY","PK"],"is_corresponding":true,"raw_author_name":"Muhammad Sohail","raw_affiliation_strings":["Department of Pharmacy, COMSATS University, Islamabad, Abbottabad Campus, 22010, Pakistan","Faculty of Pharmacy, Cyprus International University, Nicosia, 99258, Cyprus"],"raw_orcid":"https://orcid.org/0000-0003-3596-1760","affiliations":[{"raw_affiliation_string":"Department of Pharmacy, COMSATS University, Islamabad, Abbottabad Campus, 22010, Pakistan","institution_ids":["https://openalex.org/I16076960"]},{"raw_affiliation_string":"Faculty of Pharmacy, Cyprus International University, Nicosia, 99258, Cyprus","institution_ids":["https://openalex.org/I16197041"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101885142","display_name":"Arshad Mahmood","orcid":"https://orcid.org/0000-0001-5080-016X","observed_orcids":["https://orcid.org/0000-0001-5080-016X"]},"institutions":[{"id":"https://openalex.org/I161913731","display_name":"Al Ain University","ror":"https://ror.org/023abrt21","country_code":"AE","type":"education","lineage":["https://openalex.org/I161913731"]}],"countries":["AE"],"is_corresponding":false,"raw_author_name":"Arshad Mahmood","raw_affiliation_strings":["AU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates","College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AU Health and Biomedical Research Center, Al Ain University, Abu Dhabi, United Arab Emirates","institution_ids":["https://openalex.org/I161913731"]},{"raw_affiliation_string":"College of Pharmacy, Al Ain University, Abu Dhabi, United Arab Emirates","institution_ids":["https://openalex.org/I161913731"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031239861","display_name":"Syed Ahmed Shah","orcid":"https://orcid.org/0009-0009-1865-0806","observed_orcids":["https://orcid.org/0009-0009-1865-0806"]},"institutions":[{"id":"https://openalex.org/I4210100043","display_name":"Superior University","ror":"https://ror.org/00yh88643","country_code":"PK","type":"education","lineage":["https://openalex.org/I4210100043"]},{"id":"https://openalex.org/I4210119410","display_name":"Institute of Fundamental Technological Research","ror":"https://ror.org/03fs4aq04","country_code":"PL","type":"facility","lineage":["https://openalex.org/I4210119410","https://openalex.org/I99542240"]},{"id":"https://openalex.org/I99542240","display_name":"Polish Academy of Sciences","ror":"https://ror.org/01dr6c206","country_code":"PL","type":"government","lineage":["https://openalex.org/I99542240"]}],"countries":["PK","PL"],"is_corresponding":false,"raw_author_name":"Syed Ahmed Shah","raw_affiliation_strings":["Department of Biosystems and Soft Matters, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, 02-106, Poland","Department of Pharmaceutical Sciences, The Superior University, Lahore, 54600, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biosystems and Soft Matters, Institute of Fundamental Technological Research, Polish Academy of Sciences, Warsaw, 02-106, Poland","institution_ids":["https://openalex.org/I4210119410","https://openalex.org/I99542240"]},{"raw_affiliation_string":"Department of Pharmaceutical Sciences, The Superior University, Lahore, 54600, Pakistan","institution_ids":["https://openalex.org/I4210100043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006310875","display_name":"Aya Hamid Mohammad Qalawlus","orcid":"https://orcid.org/0009-0007-6321-5382","observed_orcids":["https://orcid.org/0009-0007-6321-5382"]},"institutions":[{"id":"https://openalex.org/I16197041","display_name":"Cyprus International University","ror":"https://ror.org/04mk5mk38","country_code":"CY","type":"education","lineage":["https://openalex.org/I16197041"]}],"countries":["CY"],"is_corresponding":false,"raw_author_name":"Aya Hamid Mohammad Qalawlus","raw_affiliation_strings":["Faculty of Pharmacy, Cyprus International University, Nicosia, 99258, Cyprus"],"raw_orcid":"https://orcid.org/0009-0007-6321-5382","affiliations":[{"raw_affiliation_string":"Faculty of Pharmacy, Cyprus International University, Nicosia, 99258, Cyprus","institution_ids":["https://openalex.org/I16197041"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033738855","display_name":"Touba Khaliq","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I16076960","display_name":"COMSATS University Islamabad","ror":"https://ror.org/00nqqvk19","country_code":"PK","type":"education","lineage":["https://openalex.org/I16076960"]}],"countries":["PK"],"is_corresponding":false,"raw_author_name":"Touba Khaliq","raw_affiliation_strings":["Department of Pharmacy, COMSATS University, Islamabad, Abbottabad Campus, 22010, Pakistan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacy, COMSATS University, Islamabad, Abbottabad Campus, 22010, Pakistan","institution_ids":["https://openalex.org/I16076960"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5101678546"],"corresponding_institution_ids":["https://openalex.org/I16076960","https://openalex.org/I16197041"],"apc_list":{"value":3140,"currency":"USD","value_usd":3140},"apc_paid":null,"fwci":0.8506,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.61428282,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"91","issue":null,"first_page":"105291","last_page":"105291"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.6366999745368958,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.6366999745368958,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10256","display_name":"Drug Solubulity and Delivery Systems","score":0.19130000472068787,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10920","display_name":"Advanced Drug Delivery Systems","score":0.12610000371932983,"subfield":{"id":"https://openalex.org/subfields/3003","display_name":"Pharmaceutical Science"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/silymarin","display_name":"silymarin","score":0.8809999823570251},{"id":"https://openalex.org/keywords/nanocrystals","display_name":"nanocrystals","score":0.8519999980926514},{"id":"https://openalex.org/keywords/injectable-hydrogel","display_name":"injectable hydrogel","score":0.8489999771118164},{"id":"https://openalex.org/keywords/collagen","display_name":"collagen","score":0.8529999852180481},{"id":"https://openalex.org/keywords/sodium-alginate","display_name":"sodium alginate","score":1.0},{"id":"https://openalex.org/keywords/pluronic-f127","display_name":"Pluronic F127","score":0.890999972820282},{"id":"https://openalex.org/keywords/poorly-water-soluble-drugs","display_name":"poorly water-soluble drugs","score":0.8349999785423279},{"id":"https://openalex.org/keywords/bioavailability-enhancement","display_name":"bioavailability enhancement","score":0.8429999947547913},{"id":"https://openalex.org/keywords/controlled-drug-release","display_name":"controlled drug release","score":0.8360000252723694},{"id":"https://openalex.org/keywords/antisolvent-precipitation","display_name":"antisolvent precipitation","score":0.8769999742507935},{"id":"https://openalex.org/keywords/polyvinylpyrrolidone-stabilizer","display_name":"polyvinylpyrrolidone stabilizer","score":0.765999972820282},{"id":"https://openalex.org/keywords/sodium-dodecyl-sulfate","display_name":"sodium dodecyl sulfate","score":0.9660000205039978},{"id":"https://openalex.org/keywords/in-vitro-drug-release","display_name":"in vitro drug release","score":0.5170000195503235},{"id":"https://openalex.org/keywords/pharmacokinetics","display_name":"pharmacokinetics","score":0.8859999775886536},{"id":"https://openalex.org/keywords/biodegradability","display_name":"biodegradability","score":0.628000020980835}],"concepts":[{"id":"https://openalex.org/C2777230088","wikidata":"https://www.wikidata.org/wiki/Q864426","display_name":"Biocompatibility","level":2,"score":0.7158259153366089},{"id":"https://openalex.org/C60100273","wikidata":"https://www.wikidata.org/wiki/Q902806","display_name":"Thermogravimetric analysis","level":2,"score":0.6814506649971008},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.6644994616508484},{"id":"https://openalex.org/C2778636629","wikidata":"https://www.wikidata.org/wiki/Q422649","display_name":"Biopolymer","level":3,"score":0.6321608424186707},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.5652743577957153},{"id":"https://openalex.org/C101335993","wikidata":"https://www.wikidata.org/wiki/Q408943","display_name":"Poloxamer","level":4,"score":0.5367506742477417},{"id":"https://openalex.org/C181389837","wikidata":"https://www.wikidata.org/wiki/Q461809","display_name":"Bioavailability","level":2,"score":0.5345479846000671},{"id":"https://openalex.org/C155574463","wikidata":"https://www.wikidata.org/wiki/Q170731","display_name":"Solubility","level":2,"score":0.5340209603309631},{"id":"https://openalex.org/C175854130","wikidata":"https://www.wikidata.org/wiki/Q98276914","display_name":"Nanocrystal","level":2,"score":0.494599312543869},{"id":"https://openalex.org/C160892712","wikidata":"https://www.wikidata.org/wiki/Q901559","display_name":"Fourier transform infrared spectroscopy","level":2,"score":0.4803134799003601},{"id":"https://openalex.org/C108586683","wikidata":"https://www.wikidata.org/wiki/Q17164826","display_name":"Self-healing hydrogels","level":2,"score":0.44163772463798523},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.41511696577072144},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.3722379803657532},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.33481454849243164},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.2829834818840027},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.20962560176849365},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.19265636801719666},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.10855010151863098},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jddst.2023.105291","doi":"https://doi.org/10.1016/j.jddst.2023.105291","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jddst.2023.105291","pdf_url":null,"source":{"id":"https://openalex.org/S97205441","display_name":"Journal of Drug Delivery Science and Technology","issn_l":"1773-2247","issn":["1773-2247","2588-8943"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Drug Delivery Science and Technology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G909930707","display_name":null,"funder_award_id":"5296/Federal/ NRPU/R&D/HEC/2016","funder_id":"https://openalex.org/F4320322799","funder_display_name":"Higher Education Commission, Pakistan"}],"funders":[{"id":"https://openalex.org/F4320322799","display_name":"Higher Education Commission, Pakistan","ror":"https://ror.org/038y3sz68"},{"id":"https://openalex.org/F4320326275","display_name":"Higher Education Commision, Pakistan","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":116,"referenced_works":["https://openalex.org/W44078951","https://openalex.org/W423200366","https://openalex.org/W1751092985","https://openalex.org/W1914531282","https://openalex.org/W1973488964","https://openalex.org/W1983162648","https://openalex.org/W1984615933","https://openalex.org/W1994272580","https://openalex.org/W2009512919","https://openalex.org/W2012048666","https://openalex.org/W2017532476","https://openalex.org/W2026010448","https://openalex.org/W2029993180","https://openalex.org/W2036966678","https://openalex.org/W2038287648","https://openalex.org/W2042772602","https://openalex.org/W2043234704","https://openalex.org/W2053994461","https://openalex.org/W2054260281","https://openalex.org/W2060835907","https://openalex.org/W2062730553","https://openalex.org/W2068796502","https://openalex.org/W2091357955","https://openalex.org/W2094239465","https://openalex.org/W2108602557","https://openalex.org/W2129980995","https://openalex.org/W2142110193","https://openalex.org/W2145012502","https://openalex.org/W2192862456","https://openalex.org/W2192972939","https://openalex.org/W2328305925","https://openalex.org/W2408652960","https://openalex.org/W2464709764","https://openalex.org/W2466078731","https://openalex.org/W2505929174","https://openalex.org/W2508732446","https://openalex.org/W2580291574","https://openalex.org/W2590011078","https://openalex.org/W2591599446","https://openalex.org/W2604726080","https://openalex.org/W2609432871","https://openalex.org/W2613225103","https://openalex.org/W2737091599","https://openalex.org/W2772322301","https://openalex.org/W2792122318","https://openalex.org/W2792517670","https://openalex.org/W2799550078","https://openalex.org/W2801338974","https://openalex.org/W2802112634","https://openalex.org/W2887940060","https://openalex.org/W2890341825","https://openalex.org/W2895772659","https://openalex.org/W2901383564","https://openalex.org/W2912909421","https://openalex.org/W2926432102","https://openalex.org/W2938644688","https://openalex.org/W2945078700","https://openalex.org/W2945194377","https://openalex.org/W2951706013","https://openalex.org/W2955410572","https://openalex.org/W2956564433","https://openalex.org/W2959801767","https://openalex.org/W2962858782","https://openalex.org/W2967100649","https://openalex.org/W2969712477","https://openalex.org/W2981704342","https://openalex.org/W2983511228","https://openalex.org/W2990252829","https://openalex.org/W2996185011","https://openalex.org/W2996745947","https://openalex.org/W2998979362","https://openalex.org/W2998980500","https://openalex.org/W2999384992","https://openalex.org/W3002902694","https://openalex.org/W3003219390","https://openalex.org/W3006243617","https://openalex.org/W3007231703","https://openalex.org/W3007683963","https://openalex.org/W3015079516","https://openalex.org/W3032714120","https://openalex.org/W3047270306","https://openalex.org/W3082500823","https://openalex.org/W3093290846","https://openalex.org/W3094074996","https://openalex.org/W3101817909","https://openalex.org/W3109508063","https://openalex.org/W3110068607","https://openalex.org/W3119683848","https://openalex.org/W3120509478","https://openalex.org/W3120854284","https://openalex.org/W3126542289","https://openalex.org/W3128485288","https://openalex.org/W3133617977","https://openalex.org/W3135057448","https://openalex.org/W3135099407","https://openalex.org/W3137492498","https://openalex.org/W3138017551","https://openalex.org/W3146799687","https://openalex.org/W3156201121","https://openalex.org/W3161845116","https://openalex.org/W3164422696","https://openalex.org/W3167485105","https://openalex.org/W3174878995","https://openalex.org/W3175637980","https://openalex.org/W3180631872","https://openalex.org/W3181153668","https://openalex.org/W3195485499","https://openalex.org/W3210881465","https://openalex.org/W3213539356","https://openalex.org/W4205302749","https://openalex.org/W4210801941","https://openalex.org/W4220832129","https://openalex.org/W4223531063","https://openalex.org/W4281393038","https://openalex.org/W4386083818","https://openalex.org/W6795217750"],"related_works":["https://openalex.org/W4286512646","https://openalex.org/W2908959301","https://openalex.org/W4226275382","https://openalex.org/W1972449870","https://openalex.org/W4404779939","https://openalex.org/W2557808493","https://openalex.org/W4282940775","https://openalex.org/W2416367724","https://openalex.org/W2978909169","https://openalex.org/W6893500989"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-12-20T00:00:00"}