{"id":"https://openalex.org/W4389955978","doi":"https://doi.org/10.1016/j.xcrm.2023.101256","title":"FLT3L-dependent dendritic cells control tumor immunity by modulating Treg and NK cell homeostasis","display_name":"FLT3L-dependent dendritic cells control tumor immunity by modulating Treg and NK cell homeostasis","publication_year":2023,"publication_date":"2023-12-01","ids":{"openalex":"https://openalex.org/W4389955978","doi":"https://doi.org/10.1016/j.xcrm.2023.101256","pmid":"https://pubmed.ncbi.nlm.nih.gov/38118422","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10772324"},"language":"en","primary_location":{"id":"doi:10.1016/j.xcrm.2023.101256","doi":"https://doi.org/10.1016/j.xcrm.2023.101256","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xcrm.2023.101256","pdf_url":"http://www.cell.com/article/S2666379123004330/pdf","source":{"id":"https://openalex.org/S4210207453","display_name":"Cell Reports Medicine","issn_l":"2666-3791","issn":["2666-3791"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.cell.com/article/S2666379123004330/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018629714","display_name":"Paul R\u00e9gnier","orcid":"https://orcid.org/0000-0002-9713-1132","observed_orcids":["https://orcid.org/0000-0002-9713-1132"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]},{"id":"https://openalex.org/I4210097159","display_name":"Assistance Publique \u2013 H\u00f4pitaux de Paris","ror":"https://ror.org/00pg5jh14","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"id":"https://openalex.org/I4387156255","display_name":"Immunologie - Immunopathologie - Immunoth\u00e9rapie","ror":"https://ror.org/05dbe0t82","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4387156255"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Paul R\u00e9gnier","raw_affiliation_strings":["Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France; Sorbonne Universit\u00e9, INSERM, UMR_S959, Immunology-Immunopathology-Immunotherapy, Paris, France; AP-HP, Groupe Hospitalier Piti\u00e9-Salp\u00eatri\u00e8re, Department of Internal Medicine and Clinical Immunology, DMU3ID, Paris, France","AP-HP, Groupe Hospitalier Piti\u00e9-Salp\u00eatri\u00e8re, Department of Internal Medicine and Clinical Immunology, DMU3ID, Paris, France","Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France","Sorbonne Universit\u00e9, INSERM, UMR_S959, Immunology-Immunopathology-Immunotherapy, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France; Sorbonne Universit\u00e9, INSERM, UMR_S959, Immunology-Immunopathology-Immunotherapy, Paris, France; AP-HP, Groupe Hospitalier Piti\u00e9-Salp\u00eatri\u00e8re, Department of Internal Medicine and Clinical Immunology, DMU3ID, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210086369","https://openalex.org/I4210097159","https://openalex.org/I4210121705","https://openalex.org/I4387156255"]},{"raw_affiliation_string":"AP-HP, Groupe Hospitalier Piti\u00e9-Salp\u00eatri\u00e8re, Department of Internal Medicine and Clinical Immunology, DMU3ID, Paris, France","institution_ids":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]},{"raw_affiliation_string":"Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369"]},{"raw_affiliation_string":"Sorbonne Universit\u00e9, INSERM, UMR_S959, Immunology-Immunopathology-Immunotherapy, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4387156255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054727978","display_name":"Mathias V\u00e9tillard","orcid":"https://orcid.org/0000-0001-5503-4900","observed_orcids":["https://orcid.org/0000-0001-5503-4900"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210130096","display_name":"Centre de Recherche sur l'Inflammation","ror":"https://ror.org/02gn50d10","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210130096"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mathias Vetillard","raw_affiliation_strings":["Universit\u00e9 de Paris Cit\u00e9, Centre for Inflammation Research, INSERM U1149, CNRS ERL8252, Paris, France; Dendritic Cells and Adaptive Immunity Unit, Institut Pasteur, Paris, France","Dendritic Cells and Adaptive Immunity Unit, Institut Pasteur, Paris, France","Universit\u00e9 de Paris Cit\u00e9, Centre for Inflammation Research, INSERM U1149, CNRS ERL8252, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Paris Cit\u00e9, Centre for Inflammation Research, INSERM U1149, CNRS ERL8252, Paris, France; Dendritic Cells and Adaptive Immunity Unit, Institut Pasteur, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I204730241","https://openalex.org/I4210130096"]},{"raw_affiliation_string":"Dendritic Cells and Adaptive Immunity Unit, Institut Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Universit\u00e9 de Paris Cit\u00e9, Centre for Inflammation Research, INSERM U1149, CNRS ERL8252, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210130096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093533277","display_name":"Ad\u00e8le Bansard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Ad\u00e8le Bansard","raw_affiliation_strings":["Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France; Universit\u00e9 Paris Cit\u00e9, Facult\u00e9 de M\u00e9decine, Paris, France","Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France","Universit\u00e9 Paris Cit\u00e9, Facult\u00e9 de M\u00e9decine, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France; Universit\u00e9 Paris Cit\u00e9, Facult\u00e9 de M\u00e9decine, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369"]},{"raw_affiliation_string":"Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369"]},{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, Facult\u00e9 de M\u00e9decine, Paris, France","institution_ids":["https://openalex.org/I204730241"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108792937","display_name":"Em\u00e9ranne Pierre","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Em\u00e9ranne Pierre","raw_affiliation_strings":["Universit\u00e9 Paris Cit\u00e9, Facult\u00e9 de M\u00e9decine, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, Facult\u00e9 de M\u00e9decine, Paris, France","institution_ids":["https://openalex.org/I204730241"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100357340","display_name":"Xinyue Li","orcid":"https://orcid.org/0009-0000-7572-970X","observed_orcids":["https://orcid.org/0009-0000-7572-970X"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4387156255","display_name":"Immunologie - Immunopathologie - Immunoth\u00e9rapie","ror":"https://ror.org/05dbe0t82","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4387156255"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Xinyue Li","raw_affiliation_strings":["Sorbonne Universit\u00e9, INSERM, UMR_S959, Immunology-Immunopathology-Immunotherapy, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Sorbonne Universit\u00e9, INSERM, UMR_S959, Immunology-Immunopathology-Immunotherapy, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4387156255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020417472","display_name":"Nicolas Cagnard","orcid":"https://orcid.org/0000-0002-9051-1896","observed_orcids":["https://orcid.org/0000-0002-9051-1896"]},"institutions":[{"id":"https://openalex.org/I4387156284","display_name":"Universit\u00e9 Paris Descartes","ror":"https://ror.org/0220k9r37","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241","https://openalex.org/I4387156284"]},{"id":"https://openalex.org/I4403386587","display_name":"Structure f\u00e9d\u00e9rative de recherche Necker","ror":"https://ror.org/053p5te48","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4403386587"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Nicolas Cagnard","raw_affiliation_strings":["Structure F\u00e9d\u00e9rative de Recherche Necker, Universit\u00e9 Paris Descartes, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Structure F\u00e9d\u00e9rative de Recherche Necker, Universit\u00e9 Paris Descartes, Paris, France","institution_ids":["https://openalex.org/I4387156284","https://openalex.org/I4403386587"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014371425","display_name":"Emmanuel L. Gautier","orcid":"https://orcid.org/0000-0003-2976-7566","observed_orcids":["https://orcid.org/0000-0003-2976-7566"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210121705","display_name":"Piti\u00e9-Salp\u00eatri\u00e8re Hospital","ror":"https://ror.org/02mh9a093","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210121705"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Emmanuel L. Gautier","raw_affiliation_strings":["Inserm, UMR_S1166, Sorbonne Universit\u00e9, H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm, UMR_S1166, Sorbonne Universit\u00e9, H\u00f4pital Piti\u00e9-Salp\u00eatri\u00e8re, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210121705"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053777631","display_name":"Pierre Guermonprez","orcid":"https://orcid.org/0000-0001-5621-2262","observed_orcids":["https://orcid.org/0000-0001-5621-2262"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210130096","display_name":"Centre de Recherche sur l'Inflammation","ror":"https://ror.org/02gn50d10","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210096427","https://openalex.org/I4210130096"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pierre Guermonprez","raw_affiliation_strings":["Universit\u00e9 de Paris Cit\u00e9, Centre for Inflammation Research, INSERM U1149, CNRS ERL8252, Paris, France; Dendritic Cells and Adaptive Immunity Unit, Institut Pasteur, Paris, France","Dendritic Cells and Adaptive Immunity Unit, Institut Pasteur, Paris, France","Universit\u00e9 de Paris Cit\u00e9, Centre for Inflammation Research, INSERM U1149, CNRS ERL8252, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Paris Cit\u00e9, Centre for Inflammation Research, INSERM U1149, CNRS ERL8252, Paris, France; Dendritic Cells and Adaptive Immunity Unit, Institut Pasteur, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I157536573","https://openalex.org/I204730241","https://openalex.org/I4210130096"]},{"raw_affiliation_string":"Dendritic Cells and Adaptive Immunity Unit, Institut Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Universit\u00e9 de Paris Cit\u00e9, Centre for Inflammation Research, INSERM U1149, CNRS ERL8252, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210130096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086699315","display_name":"B\u00e9n\u00e9dicte Manoury","orcid":"https://orcid.org/0000-0002-4827-4110","observed_orcids":["https://orcid.org/0000-0002-4827-4110","https://orcid.org/0000-0001-7784-3389"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"B\u00e9n\u00e9dicte Manoury","raw_affiliation_strings":["Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031821493","display_name":"Katrina Podsypanina","orcid":"https://orcid.org/0000-0003-4711-0859","observed_orcids":["https://orcid.org/0000-0003-4711-0859"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I2746051580","display_name":"Universit\u00e9 Paris Sciences et Lettres","ror":"https://ror.org/013cjyk83","country_code":"FR","type":"education","lineage":["https://openalex.org/I2746051580"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]},{"id":"https://openalex.org/I4210142887","display_name":"Dynamique du noyau","ror":"https://ror.org/04team556","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210142887","https://openalex.org/I80043"]},{"id":"https://openalex.org/I80043","display_name":"Institut Curie","ror":"https://ror.org/04t0gwh46","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I80043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Katrina Podsypanina","raw_affiliation_strings":["Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France; Institut Curie, PSL Research University, CNRS, Sorbonne Universit\u00e9, UMR3664, Paris, France","Institut Curie, PSL Research University, CNRS, Sorbonne Universit\u00e9, UMR3664, Paris, France","Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France; Institut Curie, PSL Research University, CNRS, Sorbonne Universit\u00e9, UMR3664, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I2746051580","https://openalex.org/I39804081","https://openalex.org/I4210086369","https://openalex.org/I4210142887","https://openalex.org/I80043"]},{"raw_affiliation_string":"Institut Curie, PSL Research University, CNRS, Sorbonne Universit\u00e9, UMR3664, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I2746051580","https://openalex.org/I39804081","https://openalex.org/I4210142887","https://openalex.org/I80043"]},{"raw_affiliation_string":"Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071579967","display_name":"Guillaume Darrasse-J\u00e8ze","orcid":"https://orcid.org/0000-0003-3069-8211","observed_orcids":["https://orcid.org/0000-0003-3069-8211"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I39804081","display_name":"Sorbonne Universit\u00e9","ror":"https://ror.org/02en5vm52","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081"]},{"id":"https://openalex.org/I4210086369","display_name":"Institut Necker Enfants Malades","ror":"https://ror.org/000nhq538","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369","https://openalex.org/I4210096427"]},{"id":"https://openalex.org/I4387156255","display_name":"Immunologie - Immunopathologie - Immunoth\u00e9rapie","ror":"https://ror.org/05dbe0t82","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4387156255"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Guillaume Darrasse-J\u00e8ze","raw_affiliation_strings":["Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France; Sorbonne Universit\u00e9, INSERM, UMR_S959, Immunology-Immunopathology-Immunotherapy, Paris, France; Universit\u00e9 Paris Cit\u00e9, Facult\u00e9 de M\u00e9decine, Paris, France. Electronic address: guillaume.darrasse-jeze@inserm.fr","Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France","Sorbonne Universit\u00e9, INSERM, UMR_S959, Immunology-Immunopathology-Immunotherapy, Paris, France","Universit\u00e9 Paris Cit\u00e9, Facult\u00e9 de M\u00e9decine, Paris, France"],"raw_orcid":"https://orcid.org/0000-0003-3069-8211","affiliations":[{"raw_affiliation_string":"Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France; Sorbonne Universit\u00e9, INSERM, UMR_S959, Immunology-Immunopathology-Immunotherapy, Paris, France; Universit\u00e9 Paris Cit\u00e9, Facult\u00e9 de M\u00e9decine, Paris, France. Electronic address: guillaume.darrasse-jeze@inserm.fr","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210086369","https://openalex.org/I4387156255"]},{"raw_affiliation_string":"Institut Necker Enfants Malades, INSERM U1151, CNRS UMR-8253, Universit\u00e9 Paris Cit\u00e9, Paris, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I4210086369"]},{"raw_affiliation_string":"Sorbonne Universit\u00e9, INSERM, UMR_S959, Immunology-Immunopathology-Immunotherapy, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4387156255"]},{"raw_affiliation_string":"Universit\u00e9 Paris Cit\u00e9, Facult\u00e9 de M\u00e9decine, Paris, France","institution_ids":["https://openalex.org/I204730241"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":15,"corresponding_author_ids":["https://openalex.org/A5071579967"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I204730241","https://openalex.org/I39804081","https://openalex.org/I4210086369","https://openalex.org/I4387156255"],"apc_list":{"value":5460,"currency":"USD","value_usd":5460},"apc_paid":{"value":5460,"currency":"USD","value_usd":5460},"fwci":2.659,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.90984336,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"4","issue":"12","first_page":"101256","last_page":"101256"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.03999999910593033,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/flt3-ligand","display_name":"Flt3 ligand","score":0.8650000095367432},{"id":"https://openalex.org/keywords/myeloid-dendritic-cells","display_name":"myeloid dendritic cells","score":0.9900000095367432},{"id":"https://openalex.org/keywords/antitumor-immunity","display_name":"antitumor immunity","score":0.8830000162124634},{"id":"https://openalex.org/keywords/regulatory-t-cells","display_name":"regulatory T cells","score":0.9620000123977661},{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.9639999866485596},{"id":"https://openalex.org/keywords/melanoma","display_name":"melanoma","score":0.921999990940094},{"id":"https://openalex.org/keywords/ctla-4-blockade","display_name":"CTLA-4 blockade","score":0.8899999856948853},{"id":"https://openalex.org/keywords/anti-pd-1-therapy","display_name":"anti-PD-1 therapy","score":0.9890000224113464},{"id":"https://openalex.org/keywords/combination-immunotherapy","display_name":"combination immunotherapy","score":0.6940000057220459},{"id":"https://openalex.org/keywords/dendritic-cell-depletion","display_name":"dendritic cell depletion","score":0.6850000023841858},{"id":"https://openalex.org/keywords/tumor-infiltrating-lymphocytes","display_name":"tumor-infiltrating lymphocytes","score":0.7120000123977661},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7350000143051147},{"id":"https://openalex.org/keywords/flt3-signaling","display_name":"FLT3 signaling","score":0.7310000061988831}],"concepts":[{"id":"https://openalex.org/C3020684253","wikidata":"https://www.wikidata.org/wiki/Q1550619","display_name":"Treg cell","level":5,"score":0.7476159334182739},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.7254323363304138},{"id":"https://openalex.org/C2779341262","wikidata":"https://www.wikidata.org/wiki/Q182581","display_name":"Immunity","level":3,"score":0.6156383752822876},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5036060214042664},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4730070233345032},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3773306906223297},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.36234188079833984},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.18768048286437988},{"id":"https://openalex.org/C79484868","wikidata":"https://www.wikidata.org/wiki/Q5971673","display_name":"IL-2 receptor","level":4,"score":0.09477558732032776}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D050378","descriptor_name":"T-Lymphocytes, Regulatory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1016/j.xcrm.2023.101256","doi":"https://doi.org/10.1016/j.xcrm.2023.101256","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xcrm.2023.101256","pdf_url":"http://www.cell.com/article/S2666379123004330/pdf","source":{"id":"https://openalex.org/S4210207453","display_name":"Cell Reports Medicine","issn_l":"2666-3791","issn":["2666-3791"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10772324","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10772324","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10772324/pdf/main.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Rep Med","raw_type":"Text"},{"id":"pmid:38118422","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38118422","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell reports. Medicine","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-04511457v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-04511457","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cell Reports Medicine, 2023, 4 (12), pp.101256. ⟨10.1016/j.xcrm.2023.101256⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:HAL:hal-04802770v1","doi":null,"is_oa":false,"landing_page_url":"http://www.cell.com/article/S2666379123004330/pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cell Reports Medicine, 2023, 4 (12), pp.101256. ⟨10.1016/j.xcrm.2023.101256⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.xcrm.2023.101256","doi":"https://doi.org/10.1016/j.xcrm.2023.101256","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.xcrm.2023.101256","pdf_url":"http://www.cell.com/article/S2666379123004330/pdf","source":{"id":"https://openalex.org/S4210207453","display_name":"Cell Reports Medicine","issn_l":"2666-3791","issn":["2666-3791"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-2","medline","norway-1","oarl","poland-20","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Reports Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1899869190","display_name":null,"funder_award_id":"CSC202206240034","funder_id":"https://openalex.org/F4320322725","funder_display_name":"China Scholarship Council"},{"id":"https://openalex.org/G2075927157","display_name":null,"funder_award_id":"PLBIO2019-075","funder_id":"https://openalex.org/F4320323807","funder_display_name":"Institut National Du Cancer"},{"id":"https://openalex.org/G3113876670","display_name":null,"funder_award_id":"PLBIO_2019","funder_id":"https://openalex.org/F4320323807","funder_display_name":"Institut National Du Cancer"},{"id":"https://openalex.org/G3389538103","display_name":null,"funder_award_id":"TANC16319","funder_id":"https://openalex.org/F4320322363","funder_display_name":"Ligue Contre le Cancer"},{"id":"https://openalex.org/G5809394419","display_name":null,"funder_award_id":"PJA20141201668","funder_id":"https://openalex.org/F4320322361","funder_display_name":"Fondation ARC pour la Recherche sur le Cancer"}],"funders":[{"id":"https://openalex.org/F4320308007","display_name":"Target Corporation","ror":"https://ror.org/05mkyac79"},{"id":"https://openalex.org/F4320309749","display_name":"Association pour la Recherche sur le Cancer","ror":"https://ror.org/0489qz649"},{"id":"https://openalex.org/F4320320893","display_name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","ror":"https://ror.org/02vjkv261"},{"id":"https://openalex.org/F4320322361","display_name":"Fondation ARC pour la Recherche sur le Cancer","ror":"https://ror.org/0489qz649"},{"id":"https://openalex.org/F4320322363","display_name":"Ligue Contre le Cancer","ror":"https://ror.org/00rkrv905"},{"id":"https://openalex.org/F4320322725","display_name":"China Scholarship Council","ror":"https://ror.org/04atp4p48"},{"id":"https://openalex.org/F4320323807","display_name":"Institut National Du Cancer","ror":"https://ror.org/03m8vkq32"},{"id":"https://openalex.org/F4320331438","display_name":"Universit\u00e9 de Paris","ror":"https://ror.org/05f82e368"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4389955978.pdf","grobid_xml":"https://content.openalex.org/works/W4389955978.grobid-xml"},"referenced_works_count":171,"referenced_works":["https://openalex.org/W78744612","https://openalex.org/W130367931","https://openalex.org/W232742645","https://openalex.org/W256420660","https://openalex.org/W1084046362","https://openalex.org/W1490590930","https://openalex.org/W1493941926","https://openalex.org/W1505013360","https://openalex.org/W1517043382","https://openalex.org/W1522859339","https://openalex.org/W1551802166","https://openalex.org/W1586984865","https://openalex.org/W1604283084","https://openalex.org/W1621316170","https://openalex.org/W1640609747","https://openalex.org/W1661544713","https://openalex.org/W1755415491","https://openalex.org/W1787716617","https://openalex.org/W1822927306","https://openalex.org/W1945216762","https://openalex.org/W1964389846","https://openalex.org/W1966315835","https://openalex.org/W1972166497","https://openalex.org/W1976199086","https://openalex.org/W1985157285","https://openalex.org/W1986143731","https://openalex.org/W1996922969","https://openalex.org/W1997708871","https://openalex.org/W2002398236","https://openalex.org/W2004774344","https://openalex.org/W2014035331","https://openalex.org/W2017239249","https://openalex.org/W2020313517","https://openalex.org/W2020728494","https://openalex.org/W2021377837","https://openalex.org/W2022262230","https://openalex.org/W2022307983","https://openalex.org/W2025635725","https://openalex.org/W2027115443","https://openalex.org/W2028091596","https://openalex.org/W2028597547","https://openalex.org/W2029771914","https://openalex.org/W2032869058","https://openalex.org/W2036611941","https://openalex.org/W2037380046","https://openalex.org/W2039248453","https://openalex.org/W2041808941","https://openalex.org/W2046505430","https://openalex.org/W2047102094","https://openalex.org/W2047598314","https://openalex.org/W2048424790","https://openalex.org/W2048793063","https://openalex.org/W2049360002","https://openalex.org/W2050502992","https://openalex.org/W2050558522","https://openalex.org/W2051582909","https://openalex.org/W2054581136","https://openalex.org/W2054945577","https://openalex.org/W2056939173","https://openalex.org/W2060077121","https://openalex.org/W2061071534","https://openalex.org/W2069545220","https://openalex.org/W2071432029","https://openalex.org/W2085106134","https://openalex.org/W2086595653","https://openalex.org/W2090685407","https://openalex.org/W2092191659","https://openalex.org/W2094112441","https://openalex.org/W2094254406","https://openalex.org/W2096625946","https://openalex.org/W2100378064","https://openalex.org/W2102537478","https://openalex.org/W2104732141","https://openalex.org/W2105983154","https://openalex.org/W2106728539","https://openalex.org/W2106883237","https://openalex.org/W2107830035","https://openalex.org/W2110639872","https://openalex.org/W2111975769","https://openalex.org/W2112601576","https://openalex.org/W2112744121","https://openalex.org/W2113030185","https://openalex.org/W2114738239","https://openalex.org/W2115359896","https://openalex.org/W2115889659","https://openalex.org/W2124060773","https://openalex.org/W2124927041","https://openalex.org/W2126705611","https://openalex.org/W2127144270","https://openalex.org/W2128577473","https://openalex.org/W2130196278","https://openalex.org/W2133062667","https://openalex.org/W2135908929","https://openalex.org/W2137670912","https://openalex.org/W2138002048","https://openalex.org/W2138165953","https://openalex.org/W2138733343","https://openalex.org/W2139091375","https://openalex.org/W2139626319","https://openalex.org/W2141214625","https://openalex.org/W2141363604","https://openalex.org/W2142285575","https://openalex.org/W2142838774","https://openalex.org/W2144144301","https://openalex.org/W2147350757","https://openalex.org/W2148343285","https://openalex.org/W2149032069","https://openalex.org/W2150678612","https://openalex.org/W2150892663","https://openalex.org/W2151369808","https://openalex.org/W2151551667","https://openalex.org/W2153550772","https://openalex.org/W2156831625","https://openalex.org/W2157737696","https://openalex.org/W2159966160","https://openalex.org/W2159987542","https://openalex.org/W2160117150","https://openalex.org/W2160864702","https://openalex.org/W2161792071","https://openalex.org/W2163240418","https://openalex.org/W2163243560","https://openalex.org/W2164514428","https://openalex.org/W2169593537","https://openalex.org/W2169988783","https://openalex.org/W2177188076","https://openalex.org/W2207804031","https://openalex.org/W2248602641","https://openalex.org/W2266883041","https://openalex.org/W2305631593","https://openalex.org/W2341604280","https://openalex.org/W2403954860","https://openalex.org/W2417761579","https://openalex.org/W2461271870","https://openalex.org/W2535141202","https://openalex.org/W2560367415","https://openalex.org/W2560967803","https://openalex.org/W2605810679","https://openalex.org/W2607137647","https://openalex.org/W2610228741","https://openalex.org/W2625185605","https://openalex.org/W2625822122","https://openalex.org/W2748037493","https://openalex.org/W2769822270","https://openalex.org/W2787835497","https://openalex.org/W2789293028","https://openalex.org/W2792513622","https://openalex.org/W2793102213","https://openalex.org/W2795140618","https://openalex.org/W2802668914","https://openalex.org/W2808909747","https://openalex.org/W2843629388","https://openalex.org/W2904099327","https://openalex.org/W2932352133","https://openalex.org/W2941582519","https://openalex.org/W3005015205","https://openalex.org/W3013413712","https://openalex.org/W3017272456","https://openalex.org/W3086074081","https://openalex.org/W3133820561","https://openalex.org/W3137573777","https://openalex.org/W3168169234","https://openalex.org/W3189614948","https://openalex.org/W4214873606","https://openalex.org/W4294904774","https://openalex.org/W6629554784","https://openalex.org/W6635859037","https://openalex.org/W6638265581","https://openalex.org/W6638420203","https://openalex.org/W6646984099","https://openalex.org/W6675430841","https://openalex.org/W6682156754"],"related_works":["https://openalex.org/W4416449030","https://openalex.org/W4313374675","https://openalex.org/W4385699317","https://openalex.org/W4390921276","https://openalex.org/W3137573777","https://openalex.org/W2094215026","https://openalex.org/W4248010567","https://openalex.org/W2067873293","https://openalex.org/W2000574930","https://openalex.org/W2082575954"],"abstract_inverted_index":{"FLT3-L-dependent":[0],"classical":[1],"dendritic":[2],"cells":[3,55],"(cDCs)":[4],"recruit":[5],"anti-tumor":[6,69],"and":[7,56,60,109],"tumor-protecting":[8],"lymphocytes.":[9],"We":[10],"evaluate":[11],"cancer":[12],"growth":[13],"in":[14,34,93,99,129,139,155],"mice":[15,35],"with":[16,36,71,90],"low,":[17],"normal,":[18],"or":[19,27],"high":[20,28,79],"levels":[21,126],"of":[22,30,52,58,74,106,115,124],"cDCs.":[23],"Paradoxically,":[24],"both":[25],"low":[26,39],"numbers":[29,65,147],"cDCs":[31],"improve":[32],"survival":[33,114,128],"melanoma.":[37],"In":[38],"cDC":[40,64,95,101,107,125,134,146],"context,":[41],"tumors":[42],"are":[43],"restrained":[44],"by":[45],"the":[46,67,94,100,121],"adaptive":[47],"immune":[48],"system":[49],"through":[50],"influx":[51],"effector":[53],"T":[54],"depletion":[57,111],"Tregs":[59],"NK":[61,76],"cells.":[62],"High":[63],"favor":[66],"innate":[68],"response,":[70],"massive":[72],"recruitment":[73],"activated":[75],"cells,":[77],"despite":[78],"Treg":[80,110],"infiltration.":[81],"Anti":[82],"CTLA-4":[83],"but":[84,97],"not":[85,98],"anti":[86],"PD-1":[87],"therapy":[88,92],"synergizes":[89],"FLT3-L":[91],"Hi":[96,135],"Lo":[102,137],"context.":[103],"A":[104],"combination":[105],"boost":[108],"dramatically":[112],"improves":[113],"tumor-bearing":[116],"mice.":[117],"Transcriptomic":[118],"data":[119],"confirm":[120],"paradoxical":[122],"effect":[123],"on":[127],"several":[130],"human":[131,156],"tumor":[132],"types.":[133],"-Treg":[136],"state":[138],"such":[140],"patients":[141],"predicts":[142],"best":[143],"survival.":[144],"Modulating":[145],"via":[148],"FLT3":[149],"signaling":[150],"may":[151],"have":[152],"therapeutic":[153],"potential":[154],"cancer.":[157]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":10},{"year":2024,"cited_by_count":7}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2023-12-20T00:00:00"}