{"id":"https://openalex.org/W4389954503","doi":"https://doi.org/10.1016/j.radonc.2023.110065","title":"An open source auto-segmentation algorithm for delineating heart and substructures \u2013 Development and validation within a multicenter lung cancer cohort","display_name":"An open source auto-segmentation algorithm for delineating heart and substructures \u2013 Development and validation within a multicenter lung cancer cohort","publication_year":2023,"publication_date":"2023-12-18","ids":{"openalex":"https://openalex.org/W4389954503","doi":"https://doi.org/10.1016/j.radonc.2023.110065","pmid":"https://pubmed.ncbi.nlm.nih.gov/38122851"},"language":"en","primary_location":{"id":"doi:10.1016/j.radonc.2023.110065","doi":"https://doi.org/10.1016/j.radonc.2023.110065","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.radonc.2023.110065","pdf_url":null,"source":{"id":"https://openalex.org/S144507673","display_name":"Radiotherapy and Oncology","issn_l":"0167-8140","issn":["0167-8140","1879-0887"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiotherapy and Oncology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1016/j.radonc.2023.110065","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089119281","display_name":"Agon Olloni","orcid":"https://orcid.org/0000-0001-9374-9034","observed_orcids":["https://orcid.org/0000-0001-9374-9034"]},"institutions":[{"id":"https://openalex.org/I177969490","display_name":"University of Southern Denmark","ror":"https://ror.org/03yrrjy16","country_code":"DK","type":"education","lineage":["https://openalex.org/I177969490"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801498763"]}],"countries":["DK"],"is_corresponding":true,"raw_author_name":"Agon Olloni","raw_affiliation_strings":["Department of Oncology, Odense University Hospital, Denmark; Department of Clinical Research, University of Southern Denmark, Denmark; Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Denmark. Electronic address: agon.olloni@rsyd.dk","Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Denmark","Department of Clinical Research, University of Southern Denmark, Denmark","Department of Oncology, Odense University Hospital, Denmark"],"raw_orcid":"https://orcid.org/0000-0001-9374-9034","affiliations":[{"raw_affiliation_string":"Department of Oncology, Odense University Hospital, Denmark; Department of Clinical Research, University of Southern Denmark, Denmark; Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Denmark. Electronic address: agon.olloni@rsyd.dk","institution_ids":["https://openalex.org/I177969490","https://openalex.org/I2801498763"]},{"raw_affiliation_string":"Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I2801498763"]},{"raw_affiliation_string":"Department of Clinical Research, University of Southern Denmark, Denmark","institution_ids":["https://openalex.org/I177969490"]},{"raw_affiliation_string":"Department of Oncology, Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I2801498763"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073947915","display_name":"Ebbe Laugaard Lorenzen","orcid":"https://orcid.org/0000-0003-1895-733X","observed_orcids":["https://orcid.org/0000-0003-1895-733X"]},"institutions":[{"id":"https://openalex.org/I177969490","display_name":"University of Southern Denmark","ror":"https://ror.org/03yrrjy16","country_code":"DK","type":"education","lineage":["https://openalex.org/I177969490"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801498763"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Ebbe Laugaard Lorenzen","raw_affiliation_strings":["Department of Clinical Research, University of Southern Denmark, Denmark; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark","Department of Clinical Research, University of Southern Denmark, Denmark","Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Research, University of Southern Denmark, Denmark; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I177969490","https://openalex.org/I2801498763"]},{"raw_affiliation_string":"Department of Clinical Research, University of Southern Denmark, Denmark","institution_ids":["https://openalex.org/I177969490"]},{"raw_affiliation_string":"Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I2801498763"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061022644","display_name":"Stefan Starup Jeppesen","orcid":"https://orcid.org/0000-0003-2738-0069","observed_orcids":["https://orcid.org/0000-0003-2738-0069"]},"institutions":[{"id":"https://openalex.org/I177969490","display_name":"University of Southern Denmark","ror":"https://ror.org/03yrrjy16","country_code":"DK","type":"education","lineage":["https://openalex.org/I177969490"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801498763"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Stefan Starup Jeppesen","raw_affiliation_strings":["Department of Oncology, Odense University Hospital, Denmark; Department of Clinical Research, University of Southern Denmark, Denmark; Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Denmark","Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Denmark","Department of Clinical Research, University of Southern Denmark, Denmark","Department of Oncology, Odense University Hospital, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Odense University Hospital, Denmark; Department of Clinical Research, University of Southern Denmark, Denmark; Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I177969490","https://openalex.org/I2801498763"]},{"raw_affiliation_string":"Academy of Geriatric Cancer Research (AgeCare), Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I2801498763"]},{"raw_affiliation_string":"Department of Clinical Research, University of Southern Denmark, Denmark","institution_ids":["https://openalex.org/I177969490"]},{"raw_affiliation_string":"Department of Oncology, Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I2801498763"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014201622","display_name":"Axel Cosmus Pyndt Diederichsen","orcid":"https://orcid.org/0000-0002-1285-4826","observed_orcids":["https://orcid.org/0000-0002-1285-4826"]},"institutions":[{"id":"https://openalex.org/I177969490","display_name":"University of Southern Denmark","ror":"https://ror.org/03yrrjy16","country_code":"DK","type":"education","lineage":["https://openalex.org/I177969490"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801498763"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Axel Diederichsen","raw_affiliation_strings":["Department of Clinical Research, University of Southern Denmark, Denmark; Department of Cardiology, Odense University Hospital, Denmark","Department of Cardiology, Odense University Hospital, Denmark","Department of Clinical Research, University of Southern Denmark, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Research, University of Southern Denmark, Denmark; Department of Cardiology, Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I177969490","https://openalex.org/I2801498763"]},{"raw_affiliation_string":"Department of Cardiology, Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I2801498763"]},{"raw_affiliation_string":"Department of Clinical Research, University of Southern Denmark, Denmark","institution_ids":["https://openalex.org/I177969490"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090889247","display_name":"Robert Finnegan","orcid":"https://orcid.org/0000-0003-4728-8462","observed_orcids":["https://orcid.org/0000-0003-4728-8462"]},"institutions":[{"id":"https://openalex.org/I2800079252","display_name":"Royal North Shore Hospital","ror":"https://ror.org/02gs2e959","country_code":"AU","type":"healthcare","lineage":["https://openalex.org/I2800079252"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Robert Finnegan","raw_affiliation_strings":["Northern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW, Australia"],"raw_orcid":"https://orcid.org/0000-0003-4728-8462","affiliations":[{"raw_affiliation_string":"Northern Sydney Cancer Centre, Royal North Shore Hospital, St Leonards, NSW, Australia","institution_ids":["https://openalex.org/I2800079252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080524605","display_name":"Lone Hoffmann","orcid":"https://orcid.org/0000-0002-3575-0421","observed_orcids":["https://orcid.org/0000-0002-3575-0421"]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]},{"id":"https://openalex.org/I2802335433","display_name":"Aarhus University Hospital","ror":"https://ror.org/040r8fr65","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802335433"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Lone Hoffmann","raw_affiliation_strings":["Department of Oncology, Aarhus University Hospital, Denmark; Department of Clinical Medicine, Faculty of Health Sciences, Aarhus University, Denmark","Department of Clinical Medicine, Faculty of Health Sciences, Aarhus University, Denmark","Department of Oncology, Aarhus University Hospital, Denmark"],"raw_orcid":"https://orcid.org/0000-0002-3575-0421","affiliations":[{"raw_affiliation_string":"Department of Oncology, Aarhus University Hospital, Denmark; Department of Clinical Medicine, Faculty of Health Sciences, Aarhus University, Denmark","institution_ids":["https://openalex.org/I204337017","https://openalex.org/I2802335433"]},{"raw_affiliation_string":"Department of Clinical Medicine, Faculty of Health Sciences, Aarhus University, Denmark","institution_ids":["https://openalex.org/I204337017"]},{"raw_affiliation_string":"Department of Oncology, Aarhus University Hospital, Denmark","institution_ids":["https://openalex.org/I2802335433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029222548","display_name":"Charlotte Kristiansen","orcid":"https://orcid.org/0000-0002-8073-5781","observed_orcids":["https://orcid.org/0000-0002-8073-5781"]},"institutions":[{"id":"https://openalex.org/I4210091196","display_name":"Vejle Sygehus","ror":"https://ror.org/00e8ar137","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210091196","https://openalex.org/I4210142184"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Charlotte Kristiansen","raw_affiliation_strings":["Department of Oncology, Vejle Hospital University Hospital of Southern Denmark, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Vejle Hospital University Hospital of Southern Denmark, Denmark","institution_ids":["https://openalex.org/I4210091196"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015027431","display_name":"Marianne Marquard Knap","orcid":"https://orcid.org/0000-0001-6215-8071","observed_orcids":["https://orcid.org/0000-0001-6215-8071"]},"institutions":[{"id":"https://openalex.org/I2802335433","display_name":"Aarhus University Hospital","ror":"https://ror.org/040r8fr65","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802335433"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Marianne Knap","raw_affiliation_strings":["Department of Oncology, Aarhus University Hospital, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Aarhus University Hospital, Denmark","institution_ids":["https://openalex.org/I2802335433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110742843","display_name":"Marie Louise Holm Milo","orcid":"https://orcid.org/0009-0005-3474-4344","observed_orcids":["https://orcid.org/0009-0005-3474-4344"]},"institutions":[{"id":"https://openalex.org/I2799976261","display_name":"Aalborg University Hospital","ror":"https://ror.org/02jk5qe80","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799976261"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Marie Louise Holm Milo","raw_affiliation_strings":["Department of Oncology, Aalborg University Hospital, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Aalborg University Hospital, Denmark","institution_ids":["https://openalex.org/I2799976261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015653579","display_name":"Ditte Sloth M\u00f8ller","orcid":"https://orcid.org/0000-0001-9910-515X","observed_orcids":["https://orcid.org/0000-0001-9910-515X"]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]},{"id":"https://openalex.org/I2802335433","display_name":"Aarhus University Hospital","ror":"https://ror.org/040r8fr65","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802335433"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Ditte Sloth M\u00f8ller","raw_affiliation_strings":["Department of Oncology, Aarhus University Hospital, Denmark; Department of Clinical Medicine, Faculty of Health Sciences, Aarhus University, Denmark","Department of Clinical Medicine, Faculty of Health Sciences, Aarhus University, Denmark","Department of Oncology, Aarhus University Hospital, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Aarhus University Hospital, Denmark; Department of Clinical Medicine, Faculty of Health Sciences, Aarhus University, Denmark","institution_ids":["https://openalex.org/I204337017","https://openalex.org/I2802335433"]},{"raw_affiliation_string":"Department of Clinical Medicine, Faculty of Health Sciences, Aarhus University, Denmark","institution_ids":["https://openalex.org/I204337017"]},{"raw_affiliation_string":"Department of Oncology, Aarhus University Hospital, Denmark","institution_ids":["https://openalex.org/I2802335433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109081006","display_name":"Mette P\u00f8hl","orcid":"https://orcid.org/0000-0001-9266-8662","observed_orcids":["https://orcid.org/0000-0001-9266-8662"]},"institutions":[{"id":"https://openalex.org/I2802567020","display_name":"Copenhagen University Hospital","ror":"https://ror.org/05bpbnx46","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Mette P\u00f8hl","raw_affiliation_strings":["Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark"],"raw_orcid":"https://orcid.org/0000-0001-9266-8662","affiliations":[{"raw_affiliation_string":"Department of Oncology, Rigshospitalet, Copenhagen University Hospital, Denmark","institution_ids":["https://openalex.org/I2802567020","https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051225053","display_name":"Gitte Fredberg Persson","orcid":"https://orcid.org/0000-0002-3363-3256","observed_orcids":["https://orcid.org/0000-0002-3363-3256"]},"institutions":[{"id":"https://openalex.org/I124055696","display_name":"University of Copenhagen","ror":"https://ror.org/035b05819","country_code":"DK","type":"education","lineage":["https://openalex.org/I124055696"]},{"id":"https://openalex.org/I2801827564","display_name":"Herlev Hospital","ror":"https://ror.org/00wys9y90","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801827564","https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802567020","display_name":"Copenhagen University Hospital","ror":"https://ror.org/05bpbnx46","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020"]},{"id":"https://openalex.org/I2802582725","display_name":"Gentofte Hospital","ror":"https://ror.org/051dzw862","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802582725"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Gitte Persson","raw_affiliation_strings":["Department of Oncology, Copenhagen University Hospital, Herlev and Gentofte, Denmark; Department of Clinical Medicine, Copenhagen University, Denmark","Department of Clinical Medicine, Copenhagen University, Denmark","Department of Oncology, Copenhagen University Hospital, Herlev and Gentofte, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Copenhagen University Hospital, Herlev and Gentofte, Denmark; Department of Clinical Medicine, Copenhagen University, Denmark","institution_ids":["https://openalex.org/I124055696","https://openalex.org/I2801827564","https://openalex.org/I2802567020","https://openalex.org/I2802582725"]},{"raw_affiliation_string":"Department of Clinical Medicine, Copenhagen University, Denmark","institution_ids":["https://openalex.org/I124055696"]},{"raw_affiliation_string":"Department of Oncology, Copenhagen University Hospital, Herlev and Gentofte, Denmark","institution_ids":["https://openalex.org/I2802567020"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112199395","display_name":"Hella Maria Br\u00f8gger Sand","orcid":"https://orcid.org/0009-0004-4895-1080","observed_orcids":["https://orcid.org/0009-0004-4895-1080"]},"institutions":[{"id":"https://openalex.org/I2799976261","display_name":"Aalborg University Hospital","ror":"https://ror.org/02jk5qe80","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2799976261"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Hella M.B. Sand","raw_affiliation_strings":["Department of Oncology, Aalborg University Hospital, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Aalborg University Hospital, Denmark","institution_ids":["https://openalex.org/I2799976261"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067924912","display_name":"Nis Sarup","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801498763"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Nis Sarup","raw_affiliation_strings":["Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I2801498763"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049725712","display_name":"Rune Slot Thing","orcid":"https://orcid.org/0000-0002-2683-2847","observed_orcids":["https://orcid.org/0000-0002-2683-2847"]},"institutions":[{"id":"https://openalex.org/I4210091196","display_name":"Vejle Sygehus","ror":"https://ror.org/00e8ar137","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I4210091196","https://openalex.org/I4210142184"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Rune Slot Thing","raw_affiliation_strings":["Department of Oncology, Vejle Hospital University Hospital of Southern Denmark, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Vejle Hospital University Hospital of Southern Denmark, Denmark","institution_ids":["https://openalex.org/I4210091196"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056342588","display_name":"Carsten Brink","orcid":"https://orcid.org/0000-0003-3906-1962","observed_orcids":["https://orcid.org/0000-0003-3906-1962"]},"institutions":[{"id":"https://openalex.org/I177969490","display_name":"University of Southern Denmark","ror":"https://ror.org/03yrrjy16","country_code":"DK","type":"education","lineage":["https://openalex.org/I177969490"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801498763"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Carsten Brink","raw_affiliation_strings":["Department of Clinical Research, University of Southern Denmark, Denmark; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark","Department of Clinical Research, University of Southern Denmark, Denmark","Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Research, University of Southern Denmark, Denmark; Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I177969490","https://openalex.org/I2801498763"]},{"raw_affiliation_string":"Department of Clinical Research, University of Southern Denmark, Denmark","institution_ids":["https://openalex.org/I177969490"]},{"raw_affiliation_string":"Laboratory of Radiation Physics, Department of Oncology, Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I2801498763"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006082566","display_name":"Tine Schytte","orcid":"https://orcid.org/0000-0002-6705-1561","observed_orcids":["https://orcid.org/0000-0002-6705-1561"]},"institutions":[{"id":"https://openalex.org/I177969490","display_name":"University of Southern Denmark","ror":"https://ror.org/03yrrjy16","country_code":"DK","type":"education","lineage":["https://openalex.org/I177969490"]},{"id":"https://openalex.org/I2801498763","display_name":"Odense University Hospital","ror":"https://ror.org/00ey0ed83","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2801498763"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Tine Schytte","raw_affiliation_strings":["Department of Oncology, Odense University Hospital, Denmark; Department of Clinical Research, University of Southern Denmark, Denmark","Department of Clinical Research, University of Southern Denmark, Denmark","Department of Oncology, Odense University Hospital, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Odense University Hospital, Denmark; Department of Clinical Research, University of Southern Denmark, Denmark","institution_ids":["https://openalex.org/I177969490","https://openalex.org/I2801498763"]},{"raw_affiliation_string":"Department of Clinical Research, University of Southern Denmark, Denmark","institution_ids":["https://openalex.org/I177969490"]},{"raw_affiliation_string":"Department of Oncology, Odense University Hospital, Denmark","institution_ids":["https://openalex.org/I2801498763"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5089119281"],"corresponding_institution_ids":["https://openalex.org/I177969490","https://openalex.org/I2801498763"],"apc_list":{"value":3210,"currency":"USD","value_usd":3210},"apc_paid":{"value":3210,"currency":"USD","value_usd":3210},"fwci":0.5894,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.60364796,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"191","issue":null,"first_page":"110065","last_page":"110065"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9218999743461609,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9218999743461609,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.0714000016450882,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cardiac-segmentation","display_name":"cardiac image segmentation","score":0.6880000233650208},{"id":"https://openalex.org/keywords/coronary-artery-segmentation","display_name":"coronary artery segmentation","score":0.6610000133514404},{"id":"https://openalex.org/keywords/lung-cancer-radiotherapy","display_name":"lung cancer radiotherapy","score":0.781000018119812},{"id":"https://openalex.org/keywords/cardiotoxicity","display_name":"cardiotoxicity","score":0.5249999761581421},{"id":"https://openalex.org/keywords/hybrid-segmentation","display_name":"hybrid segmentation","score":0.4970000088214874},{"id":"https://openalex.org/keywords/nnu-net","display_name":"nnU-Net","score":0.8980000019073486},{"id":"https://openalex.org/keywords/atlas-based-segmentation","display_name":"atlas-based segmentation","score":0.9049999713897705},{"id":"https://openalex.org/keywords/dose-prediction","display_name":"dose prediction","score":0.5669999718666077},{"id":"https://openalex.org/keywords/open-source-software","display_name":"open source software","score":0.6110000014305115},{"id":"https://openalex.org/keywords/thoracic-radiotherapy","display_name":"thoracic radiotherapy","score":0.5339999794960022},{"id":"https://openalex.org/keywords/interobserver-variability","display_name":"interobserver variability","score":0.7059999704360962}],"concepts":[{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.681513786315918},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.6256161332130432},{"id":"https://openalex.org/C2776256026","wikidata":"https://www.wikidata.org/wiki/Q47912","display_name":"Lung cancer","level":2,"score":0.575333833694458},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5493209362030029},{"id":"https://openalex.org/C2992435398","wikidata":"https://www.wikidata.org/wiki/Q6934595","display_name":"Multicenter study","level":3,"score":0.43366384506225586},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4322267472743988},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4238815903663635},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3564842939376831},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.35415446758270264},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000528","qualifier_name":"radiation effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D008175","descriptor_name":"Lung Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1016/j.radonc.2023.110065","doi":"https://doi.org/10.1016/j.radonc.2023.110065","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.radonc.2023.110065","pdf_url":null,"source":{"id":"https://openalex.org/S144507673","display_name":"Radiotherapy and Oncology","issn_l":"0167-8140","issn":["0167-8140","1879-0887"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiotherapy and Oncology","raw_type":"journal-article"},{"id":"pmid:38122851","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38122851","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology","raw_type":"Multicenter Study"},{"id":"pmh:oai:pure.atira.dk:openaire/1d7809f2-b5d5-4dd5-a2b8-512c14224d5e","doi":null,"is_oa":true,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/1d7809f2-b5d5-4dd5-a2b8-512c14224d5e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Olloni, A, Lorenzen, E L, Jeppesen, S S, Diederichsen, A, Finnegan, R, Hoffmann, L, Kristiansen, C, Knap, M, Milo, M L H, M\u00f8ller, D S, P\u00f8hl, M, Persson, G, Sand, H M B, Sarup, N, Thing, R S, Brink, C & Schytte, T 2024, 'An open source auto-segmentation algorithm for delineating heart and substructures \u2013 Development and validation within a multicenter lung cancer cohort', Radiotherapy and Oncology, vol. 191, 110065. https://doi.org/10.1016/j.radonc.2023.110065","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.atira.dk:openaire/8547ca30-0a7a-487c-80b4-ee1b8de3fc14","doi":null,"is_oa":true,"landing_page_url":"https://vbn.aau.dk/da/publications/8547ca30-0a7a-487c-80b4-ee1b8de3fc14","pdf_url":null,"source":{"id":"https://openalex.org/S4306401731","display_name":"VBN Forskningsportal (Aalborg Universitet)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I891191580","host_organization_name":"Aalborg University","host_organization_lineage":["https://openalex.org/I891191580"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Olloni, A, Lorenzen, E L, Jeppesen, S S, Diederichsen, A, Finnegan, R, Hoffmann, L, Kristiansen, C, Knap, M, Milo, M L H, M\u00f8ller, D S, P\u00f8hl, M, Persson, G, Sand, H M B, Sarup, N, Slot Thing, R, Brink, C & Schytte, T 2024, 'An open source auto-segmentation algorithm for delineating heart and substructures - Development and validation within a multicenter lung cancer cohort', Radiotherapy and Oncology, vol. 191, 110065. https://doi.org/10.1016/j.radonc.2023.110065","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:sdu.dk:openaire/3374de04-3be2-495b-a277-ea35e25eaad9","doi":null,"is_oa":true,"landing_page_url":"https://portal.findresearcher.sdu.dk/da/publications/3374de04-3be2-495b-a277-ea35e25eaad9","pdf_url":null,"source":{"id":"https://openalex.org/S4306400423","display_name":"University of Southern Denmark Research Portal (University of Southern Denmark)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I177969490","host_organization_name":"University of Southern Denmark","host_organization_lineage":["https://openalex.org/I177969490"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Olloni, A, Lorenzen, E L, Jeppesen, S S, Diederichsen, A, Finnegan, R, Hoffmann, L, Kristiansen, C, Knap, M, Milo, M L H, M\u00f8ller, D S, P\u00f8hl, M, Persson, G, Sand, H M B, Sarup, N, Thing, R S, Brink, C & Schytte, T 2024, 'An open source auto-segmentation algorithm for delineating heart and substructures - Development and validation within a multicenter lung cancer cohort', Radiotherapy & Oncology, vol. 191, 110065. https://doi.org/10.1016/j.radonc.2023.110065","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.atira.dk:openaire/40508355-babc-4607-8b56-99558030594f","doi":null,"is_oa":true,"landing_page_url":"https://pure.au.dk/portal/en/publications/40508355-babc-4607-8b56-99558030594f","pdf_url":null,"source":null,"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Olloni, A, Lorenzen, E L, Jeppesen, S S, Diederichsen, A, Finnegan, R, Hoffmann, L, Kristiansen, C, Knap, M, Milo, M L H, M\u00f8ller, D S, P\u00f8hl, M, Persson, G, Sand, H M B, Sarup, N, Thing, R S, Brink, C & Schytte, T 2024, 'An open source auto-segmentation algorithm for delineating heart and substructures \u2013 Development and validation within a multicenter lung cancer cohort', Radiotherapy and Oncology, vol. 191, 110065. https://doi.org/10.1016/j.radonc.2023.110065","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.radonc.2023.110065","doi":"https://doi.org/10.1016/j.radonc.2023.110065","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.radonc.2023.110065","pdf_url":null,"source":{"id":"https://openalex.org/S144507673","display_name":"Radiotherapy and Oncology","issn_l":"0167-8140","issn":["0167-8140","1879-0887"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiotherapy and Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1984483689","https://openalex.org/W1987536026","https://openalex.org/W2037517514","https://openalex.org/W2154375587","https://openalex.org/W2167913161","https://openalex.org/W2560294561","https://openalex.org/W2591100698","https://openalex.org/W2596281330","https://openalex.org/W2606281753","https://openalex.org/W2610320467","https://openalex.org/W2756408450","https://openalex.org/W2805518365","https://openalex.org/W2893824814","https://openalex.org/W2901300494","https://openalex.org/W2921887739","https://openalex.org/W2952155820","https://openalex.org/W2995515529","https://openalex.org/W3014974815","https://openalex.org/W3035067918","https://openalex.org/W3035315326","https://openalex.org/W3080255616","https://openalex.org/W3085990010","https://openalex.org/W3097715046","https://openalex.org/W3110985972","https://openalex.org/W3133970023","https://openalex.org/W3193544237","https://openalex.org/W3200919600","https://openalex.org/W3210750817","https://openalex.org/W4220662190","https://openalex.org/W4224213492","https://openalex.org/W4287881720","https://openalex.org/W4319160610","https://openalex.org/W4320489889","https://openalex.org/W4323817416","https://openalex.org/W4378675816","https://openalex.org/W4392812525","https://openalex.org/W4403559229","https://openalex.org/W6958316601"],"related_works":["https://openalex.org/W4323817416","https://openalex.org/W4389943392","https://openalex.org/W4320489889","https://openalex.org/W3193544237","https://openalex.org/W3118463796","https://openalex.org/W2085143385","https://openalex.org/W2886856931","https://openalex.org/W2902582310","https://openalex.org/W3097715046","https://openalex.org/W7214377232"],"abstract_inverted_index":{"BACKGROUND":[0],"AND":[1,52],"PURPOSE:":[2],"Irradiation":[3],"of":[4,36,73,84,107,115,132,158,228,242],"the":[5,44,59,67,85,129,140,166,174,180,187,192,199,204,208,222,231,237],"heart":[6,18,48,76,122,153,209,223,243],"in":[7,202,220,247],"thoracic":[8],"cancers":[9],"raises":[10],"toxicity":[11,49],"concerns.":[12],"For":[13],"accurate":[14],"dose":[15,39,116,130,205,229,246],"estimation,":[16],"automated":[17],"and":[19,38,66,78,81,90,99,120,123,168,183,210,224,244],"substructure":[20,245],"segmentation":[21,31,56,77,83,92,182,194,216,233],"is":[22,32],"potentially":[23],"useful.":[24],"In":[25],"this":[26],"study,":[27],"a":[28,74,103,152],"hybrid":[29,55,146,215],"automatic":[30,167,181,193,232],"developed.":[33],"The":[34,54,70,87,113,145,171,214,226,250],"accuracy":[35,114],"delineation":[37,251],"predictions":[40,117],"were":[41],"evaluated,":[42],"testing":[43],"method's":[45],"potential":[46],"within":[47],"studies.":[50],"MATERIALS":[51],"METHODS:":[53],"method":[57,71,148,217],"delineated":[58],"heart,":[60],"four":[61],"chambers,":[62],"three":[63],"large":[64,248],"vessels,":[65],"coronary":[68],"arteries.":[69],"consisted":[72],"nnU-net":[75,88],"partly":[79],"atlas-":[80],"model-based":[82],"substructures.":[86,212,225],"training":[89],"atlas":[91],"was":[93,100,125,184,195,234],"based":[94],"on":[95],"lung":[96,136],"cancer":[97,137],"patients":[98,109,138],"validated":[101],"against":[102],"national":[104],"consensus":[105,141],"dataset":[106],"12":[108],"with":[110,151,160,186,236],"breast":[111],"cancer.":[112],"between":[118,165],"manual":[119,169,238],"auto-segmented":[121],"substructures":[124],"evaluated":[126],"by":[127,230],"transferring":[128],"distribution":[131,206],"240":[133],"previously":[134],"treated":[135],"to":[139,207],"data":[142],"set.":[143],"RESULTS:":[144],"auto-segmentation":[147],"performed":[149,218],"well":[150,219],"dice":[154],"similarity":[155],"coefficient":[156],"(DSC)":[157],"0.95,":[159],"no":[161],"statistically":[162],"significant":[163],"difference":[164],"delineations.":[170],"DSC":[172],"for":[173,179,256],"chambers":[175],"varied":[176],"from":[177],"0.78-0.86":[178],"comparable":[185],"inter-observer":[188],"variability.":[189],"Most":[190],"importantly,":[191],"as":[196,198],"precise":[197],"clinical":[200],"experts":[201],"predicting":[203],"all":[211],"CONCLUSION:":[213],"delineating":[221],"prediction":[227],"aligned":[235],"delineations,":[239],"enabling":[240],"measurement":[241],"cohorts.":[249],"algorithm":[252],"will":[253],"be":[254],"available":[255],"download.":[257]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-12-20T00:00:00"}
