{"id":"https://openalex.org/W4389951971","doi":"https://doi.org/10.1002/cam4.6720","title":"A recurrence\u2010predictive model based on eight genes and tumor mutational burden/microsatellite instability status in Stage II / III colorectal cancer","display_name":"A recurrence\u2010predictive model based on eight genes and tumor mutational burden/microsatellite instability status in Stage II / III colorectal cancer","publication_year":2023,"publication_date":"2023-12-19","ids":{"openalex":"https://openalex.org/W4389951971","doi":"https://doi.org/10.1002/cam4.6720","pmid":"https://pubmed.ncbi.nlm.nih.gov/38111983","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10807589"},"language":"en","primary_location":{"id":"doi:10.1002/cam4.6720","doi":"https://doi.org/10.1002/cam4.6720","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cam4.6720","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.6720","source":{"id":"https://openalex.org/S2754843627","display_name":"Cancer Medicine","issn_l":"2045-7634","issn":["2045-7634"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.6720","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5009666274","display_name":"Zhaoya Gao","orcid":"https://orcid.org/0000-0002-0874-2266","observed_orcids":["https://orcid.org/0000-0002-0874-2266"]},"institutions":[{"id":"https://openalex.org/I4210130930","display_name":"Peking University First Hospital","ror":"https://ror.org/02z1vqm45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210130930"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhaoya Gao","raw_affiliation_strings":["Department of General Surgery, Peking University First Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Peking University First Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210130930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113204977","display_name":"Zhiyi Wan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Zhiyi Wan","raw_affiliation_strings":["Genecast Biotechnology Co., Ltd., Wuxi City, Jiangsu Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genecast Biotechnology Co., Ltd., Wuxi City, Jiangsu Province, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100542949","display_name":"Pengfei Yu","orcid":"https://orcid.org/0000-0002-1947-6469","observed_orcids":["https://orcid.org/0000-0002-1947-6469","https://orcid.org/0000-0002-8361-7625"]},"institutions":[{"id":"https://openalex.org/I4210160531","display_name":"Chinese People's Liberation Army","ror":"https://ror.org/05tf9r976","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210160531"]},{"id":"https://openalex.org/I4402554004","display_name":"People's Liberation Army Air Force","ror":"https://ror.org/04f13ze88","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210160531","https://openalex.org/I4402554004"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pengfei Yu","raw_affiliation_strings":["Department of General Surgery, Air Force Medical Center, Chinese People's Liberation Army, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Air Force Medical Center, Chinese People's Liberation Army, Beijing, China","institution_ids":["https://openalex.org/I4210160531","https://openalex.org/I4402554004"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Yan Shang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210161255","display_name":"Liaoning Cancer Hospital & Institute","ror":"https://ror.org/05d659s21","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161255"]},{"id":"https://openalex.org/I91656880","display_name":"China Medical University","ror":"https://ror.org/032d4f246","country_code":"CN","type":"education","lineage":["https://openalex.org/I91656880"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yan Shang","raw_affiliation_strings":["Department of Colorectal Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang, Liaoning Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Colorectal Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang, Liaoning Province, China","institution_ids":["https://openalex.org/I4210161255","https://openalex.org/I91656880"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035507899","display_name":"Guangsheng Zhu","orcid":"https://orcid.org/0000-0001-7580-1986","observed_orcids":["https://orcid.org/0000-0001-7580-1986"]},"institutions":[{"id":"https://openalex.org/I4210160841","display_name":"Hubei Cancer Hospital","ror":"https://ror.org/05p38yh32","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160841"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guangsheng Zhu","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Hubei Cancer Hospital, Wuhan, Hubei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Hubei Cancer Hospital, Wuhan, Hubei Province, China","institution_ids":["https://openalex.org/I4210160841"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065560781","display_name":"Huiyuan Jiang","orcid":"https://orcid.org/0009-0000-0270-5408","observed_orcids":["https://orcid.org/0009-0000-0270-5408"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210102673","display_name":"Shanxi Provincial Cancer Hospital","ror":"https://ror.org/01790dx02","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210102673"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Huiyuan Jiang","raw_affiliation_strings":["Department of Colorectal and Anal Surgery, Shanxi Province Cancer Hospital/ Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Colorectal and Anal Surgery, Shanxi Province Cancer Hospital/ Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi Province, China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I200296433","https://openalex.org/I4210102673"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109118772","display_name":"Yawei Chen","orcid":"https://orcid.org/0000-0002-0085-0094","observed_orcids":["https://orcid.org/0000-0002-0085-0094"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yawei Chen","raw_affiliation_strings":["Genecast Biotechnology Co., Ltd., Wuxi City, Jiangsu Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genecast Biotechnology Co., Ltd., Wuxi City, Jiangsu Province, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026946423","display_name":"Shengzhou Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shengzhou Wang","raw_affiliation_strings":["Genecast Biotechnology Co., Ltd., Wuxi City, Jiangsu Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genecast Biotechnology Co., Ltd., Wuxi City, Jiangsu Province, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101079916","display_name":"Fuming Lei","orcid":"https://orcid.org/0000-0002-6257-0493","observed_orcids":["https://orcid.org/0000-0002-6257-0493"]},"institutions":[{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fuming Lei","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Wensheng Huang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wensheng Huang","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Qingmin Zeng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qingmin Zeng","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100782335","display_name":"Yanzhao Wang","orcid":"https://orcid.org/0000-0002-5642-7201","observed_orcids":["https://orcid.org/0000-0002-5642-7201"]},"institutions":[{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yanzhao Wang","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","Department of Pathology Peking University Shougang Hospital  Beijing China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]},{"raw_affiliation_string":"Department of Pathology Peking University Shougang Hospital  Beijing China","institution_ids":["https://openalex.org/I4210139292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082158755","display_name":"Wanshui Rong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wanshui Rong","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112883425","display_name":"Yuming Hong","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuming Hong","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113908187","display_name":"Qingkun Gao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qingkun Gao","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103040281","display_name":"Pengfei Niu","orcid":"https://orcid.org/0000-0003-4591-0051","observed_orcids":["https://orcid.org/0000-0003-4591-0051"]},"institutions":[{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pengfei Niu","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005865634","display_name":"Zhichao Zhai","orcid":"https://orcid.org/0009-0004-1430-3544","observed_orcids":["https://orcid.org/0009-0004-1430-3544"]},"institutions":[{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhichao Zhai","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ke An","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ke An","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101077615","display_name":"Changmin Ding","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Changmin Ding","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089977529","display_name":"Yunfan Wang","orcid":"https://orcid.org/0000-0002-8403-4667","observed_orcids":["https://orcid.org/0000-0002-8403-4667"]},"institutions":[{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yunfan Wang","raw_affiliation_strings":["Department of Gastrointestinal Surgery Peking University Shougang Hospital  Beijing China","Department of Pathology, Peking University Shougang Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery Peking University Shougang Hospital  Beijing China","institution_ids":["https://openalex.org/I4210139292"]},{"raw_affiliation_string":"Department of Pathology, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008379184","display_name":"Guo-Li Gu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210160531","display_name":"Chinese People's Liberation Army","ror":"https://ror.org/05tf9r976","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210160531"]},{"id":"https://openalex.org/I4402554004","display_name":"People's Liberation Army Air Force","ror":"https://ror.org/04f13ze88","country_code":"CN","type":"government","lineage":["https://openalex.org/I4210160531","https://openalex.org/I4402554004"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guoli Gu","raw_affiliation_strings":["Department of General Surgery, Air Force Medical Center, Chinese People's Liberation Army, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Air Force Medical Center, Chinese People's Liberation Army, Beijing, China","institution_ids":["https://openalex.org/I4210160531","https://openalex.org/I4402554004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100668403","display_name":"Xin Wang","orcid":"https://orcid.org/0000-0002-4715-4360","observed_orcids":["https://orcid.org/0000-0002-4715-4360"]},"institutions":[{"id":"https://openalex.org/I4210130930","display_name":"Peking University First Hospital","ror":"https://ror.org/02z1vqm45","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210130930"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xin Wang","raw_affiliation_strings":["Department of General Surgery, Peking University First Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Peking University First Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210130930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035801874","display_name":"Qingkai Meng","orcid":"https://orcid.org/0000-0001-7098-4592","observed_orcids":["https://orcid.org/0000-0001-7098-4592"]},"institutions":[{"id":"https://openalex.org/I4210161255","display_name":"Liaoning Cancer Hospital & Institute","ror":"https://ror.org/05d659s21","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210161255"]},{"id":"https://openalex.org/I91656880","display_name":"China Medical University","ror":"https://ror.org/032d4f246","country_code":"CN","type":"education","lineage":["https://openalex.org/I91656880"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Qingkai Meng","raw_affiliation_strings":["Department of Colorectal Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang, Liaoning Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Colorectal Surgery, Cancer Hospital of China Medical University, Liaoning Cancer Hospital and Institute, Shenyang, Liaoning Province, China","institution_ids":["https://openalex.org/I4210161255","https://openalex.org/I91656880"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008688516","display_name":"Shengwei Ye","orcid":"https://orcid.org/0000-0001-9543-9857","observed_orcids":["https://orcid.org/0000-0001-9543-9857"]},"institutions":[{"id":"https://openalex.org/I4210160841","display_name":"Hubei Cancer Hospital","ror":"https://ror.org/05p38yh32","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210160841"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shengwei Ye","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Hubei Cancer Hospital, Wuhan, Hubei Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Hubei Cancer Hospital, Wuhan, Hubei Province, China","institution_ids":["https://openalex.org/I4210160841"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102775281","display_name":"Haiyi Liu","orcid":"https://orcid.org/0000-0003-4289-8480","observed_orcids":["https://orcid.org/0000-0003-4289-8480"]},"institutions":[{"id":"https://openalex.org/I17721919","display_name":"Shanxi Medical University","ror":"https://ror.org/0265d1010","country_code":"CN","type":"education","lineage":["https://openalex.org/I17721919"]},{"id":"https://openalex.org/I200296433","display_name":"Chinese Academy of Medical Sciences & Peking Union Medical College","ror":"https://ror.org/02drdmm93","country_code":"CN","type":"education","lineage":["https://openalex.org/I200296433"]},{"id":"https://openalex.org/I4210102673","display_name":"Shanxi Provincial Cancer Hospital","ror":"https://ror.org/01790dx02","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210102673"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Haiyi Liu","raw_affiliation_strings":["Department of Colorectal and Anal Surgery, Shanxi Province Cancer Hospital/ Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi Province, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Colorectal and Anal Surgery, Shanxi Province Cancer Hospital/ Shanxi Hospital Affiliated to Cancer Hospital, Chinese Academy of Medical Sciences/Cancer Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi Province, China","institution_ids":["https://openalex.org/I17721919","https://openalex.org/I200296433","https://openalex.org/I4210102673"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5011450428","display_name":"Jin Fa Gu","orcid":"https://orcid.org/0000-0002-9650-1963","observed_orcids":["https://orcid.org/0000-0002-9650-1963"]},"institutions":[{"id":"https://openalex.org/I20231570","display_name":"Peking University","ror":"https://ror.org/02v51f717","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570"]},{"id":"https://openalex.org/I4210093964","display_name":"Peking University Cancer Hospital","ror":"https://ror.org/00nyxxr91","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093964"]},{"id":"https://openalex.org/I4210139292","display_name":"Peking University Shougang Hospital","ror":"https://ror.org/040rwep31","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210139292"]},{"id":"https://openalex.org/I4210160507","display_name":"Center for Life Sciences","ror":"https://ror.org/05kje8j93","country_code":"CN","type":"education","lineage":["https://openalex.org/I20231570","https://openalex.org/I4210160507","https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Jin Gu","raw_affiliation_strings":["Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Surgery Peking University Cancer Hospital &amp; Institute Beijing China","Peking University International Cancer Institute, Beijing, China","Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0002-9650-1963","affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Surgery, Peking University Shougang Hospital, Beijing, China","institution_ids":["https://openalex.org/I4210139292"]},{"raw_affiliation_string":"Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Department of Gastrointestinal Surgery Peking University Cancer Hospital &amp; Institute Beijing China","institution_ids":["https://openalex.org/I4210093964"]},{"raw_affiliation_string":"Peking University International Cancer Institute, Beijing, China","institution_ids":["https://openalex.org/I20231570"]},{"raw_affiliation_string":"Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China","institution_ids":["https://openalex.org/I20231570","https://openalex.org/I4210160507"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":13,"corresponding_author_ids":["https://openalex.org/A5008379184","https://openalex.org/A5008688516","https://openalex.org/A5011450428","https://openalex.org/A5035801874","https://openalex.org/A5100668403","https://openalex.org/A5102775281"],"corresponding_institution_ids":["https://openalex.org/I17721919","https://openalex.org/I200296433","https://openalex.org/I20231570","https://openalex.org/I4210093964","https://openalex.org/I4210102673","https://openalex.org/I4210130930","https://openalex.org/I4210139292","https://openalex.org/I4210160507","https://openalex.org/I4210160531","https://openalex.org/I4210160841","https://openalex.org/I4210161255","https://openalex.org/I4402554004","https://openalex.org/I91656880"],"apc_list":{"value":4070,"currency":"USD","value_usd":4070},"apc_paid":{"value":4070,"currency":"USD","value_usd":4070},"fwci":0.5947,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.67633229,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"13","issue":"1","first_page":"e6720","last_page":"e6720"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.8910999894142151,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.8910999894142151,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies","score":0.08429999649524689,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.014999999664723873,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/colorectal-cancer","display_name":"colorectal cancer","score":0.847000002861023},{"id":"https://openalex.org/keywords/stage-ii-iii-colorectal-cancer","display_name":"stage II and III colorectal cancer","score":0.8840000033378601},{"id":"https://openalex.org/keywords/recurrence-risk-prediction","display_name":"recurrence risk prediction","score":0.8080000281333923},{"id":"https://openalex.org/keywords/adjuvant-chemotherapy","display_name":"adjuvant chemotherapy","score":0.7870000004768372},{"id":"https://openalex.org/keywords/mutation","display_name":"genetic mutations","score":0.6370000243186951},{"id":"https://openalex.org/keywords/tumor-mutational-burden","display_name":"tumor mutational burden","score":0.9139999747276306},{"id":"https://openalex.org/keywords/microsatellite-instability","display_name":"microsatellite instability","score":1.0},{"id":"https://openalex.org/keywords/tumor-immune-infiltration","display_name":"tumor immune infiltration","score":0.6740000247955322},{"id":"https://openalex.org/keywords/tertiary-lymphoid-structures","display_name":"tertiary lymphoid structures","score":0.9879999756813049},{"id":"https://openalex.org/keywords/immunotherapy-biomarkers","display_name":"immunotherapy biomarkers","score":0.9049999713897705},{"id":"https://openalex.org/keywords/patient-stratification","display_name":"patient stratification","score":0.593999981880188}],"concepts":[{"id":"https://openalex.org/C2779767149","wikidata":"https://www.wikidata.org/wiki/Q488212","display_name":"Microsatellite instability","level":5,"score":0.8217502236366272},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.779070258140564},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.7338442802429199},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7235701084136963},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.7215577960014343},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6644861102104187},{"id":"https://openalex.org/C146357865","wikidata":"https://www.wikidata.org/wiki/Q1123245","display_name":"Stage (stratigraphy)","level":2,"score":0.5665642619132996},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.5589715242385864},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4336146414279938},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2103448212146759},{"id":"https://openalex.org/C180754005","wikidata":"https://www.wikidata.org/wiki/Q80726","display_name":"Allele","level":3,"score":0.16397684812545776},{"id":"https://openalex.org/C61320498","wikidata":"https://www.wikidata.org/wiki/Q265193","display_name":"Microsatellite","level":4,"score":0.12624618411064148},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1130865216255188},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06588223576545715},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015179","descriptor_name":"Colorectal Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D053842","descriptor_name":"Microsatellite Instability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.1002/cam4.6720","doi":"https://doi.org/10.1002/cam4.6720","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cam4.6720","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.6720","source":{"id":"https://openalex.org/S2754843627","display_name":"Cancer Medicine","issn_l":"2045-7634","issn":["2045-7634"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Medicine","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10807589","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10807589","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10807589/pdf/CAM4-13-e6720.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Med","raw_type":"Text"},{"id":"pmid:38111983","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38111983","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer medicine","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:d7229bedf41f4876aedddf55043e8382","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/d7229bedf41f4876aedddf55043e8382","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Cancer Medicine, Vol 13, Iss 1, Pp n/a-n/a (2024)","raw_type":"article"},{"id":"doi:10.60692/8b59v-w3s65","doi":"https://doi.org/10.60692/8b59v-w3s65","is_oa":true,"landing_page_url":"https://doi.org/10.60692/8b59v-w3s65","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"},{"id":"doi:10.60692/tgvr0-kch59","doi":"https://doi.org/10.60692/tgvr0-kch59","is_oa":true,"landing_page_url":"https://doi.org/10.60692/tgvr0-kch59","pdf_url":null,"source":{"id":"https://openalex.org/S7407051682","display_name":"Greater South Information System","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.1002/cam4.6720","doi":"https://doi.org/10.1002/cam4.6720","is_oa":true,"landing_page_url":"https://doi.org/10.1002/cam4.6720","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/cam4.6720","source":{"id":"https://openalex.org/S2754843627","display_name":"Cancer Medicine","issn_l":"2045-7634","issn":["2045-7634"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G7373847194","display_name":null,"funder_award_id":"2020-1","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7533051715","display_name":null,"funder_award_id":"82073223","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4389951971.pdf","grobid_xml":"https://content.openalex.org/works/W4389951971.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W1786821161","https://openalex.org/W2028433016","https://openalex.org/W2049491375","https://openalex.org/W2089711940","https://openalex.org/W2103474120","https://openalex.org/W2112382960","https://openalex.org/W2117564738","https://openalex.org/W2119938514","https://openalex.org/W2120615411","https://openalex.org/W2123879591","https://openalex.org/W2124402963","https://openalex.org/W2130794319","https://openalex.org/W2142300779","https://openalex.org/W2162102504","https://openalex.org/W2262414037","https://openalex.org/W2318500626","https://openalex.org/W2460179076","https://openalex.org/W2488353409","https://openalex.org/W2573152477","https://openalex.org/W2580867604","https://openalex.org/W2606495925","https://openalex.org/W2656808027","https://openalex.org/W2744516998","https://openalex.org/W2760942750","https://openalex.org/W2772146395","https://openalex.org/W2802206159","https://openalex.org/W2896872272","https://openalex.org/W2913729906","https://openalex.org/W2944044607","https://openalex.org/W2949273159","https://openalex.org/W2954882537","https://openalex.org/W2967681225","https://openalex.org/W3082908815","https://openalex.org/W3102943688","https://openalex.org/W3121225048","https://openalex.org/W3128646645","https://openalex.org/W3157359228","https://openalex.org/W3160935444","https://openalex.org/W3203274060","https://openalex.org/W4200273024","https://openalex.org/W4211121451","https://openalex.org/W4281738617","https://openalex.org/W4282569471","https://openalex.org/W4315642851","https://openalex.org/W4317107807","https://openalex.org/W4389951971"],"related_works":["https://openalex.org/W4315433903","https://openalex.org/W3183379693","https://openalex.org/W7143376221","https://openalex.org/W2130458871","https://openalex.org/W2987536782","https://openalex.org/W4210726429","https://openalex.org/W2148206047","https://openalex.org/W4366742549","https://openalex.org/W2047081840","https://openalex.org/W2889156515"],"abstract_inverted_index":{"BACKGROUND:":[0],"Although":[1],"adjuvant":[2],"chemotherapy":[3],"(ACT)":[4],"is":[5,231],"widely":[6],"used":[7,250],"to":[8,19,27,251],"treat":[9],"patients":[10,21,67,80,242,253],"with":[11,81,156,243],"Stage":[12,64,82],"II/III":[13,65,83,245],"colorectal":[14],"cancer":[15],"(CRC),":[16],"administering":[17],"ACT":[18,28,257],"specific":[20],"remains":[22],"a":[23,50,213,232],"challenge.":[24],"The":[25,118,208],"decision":[26],"requires":[29],"an":[30,73],"accurate":[31],"assessment":[32],"of":[33,54,75,78,239],"recurrence":[34,59,109,240],"risk":[35,53,238],"and":[36,108,144,147,162,203,258],"absolute":[37],"treatment":[38],"benefit.":[39],"However,":[40],"the":[41,124,168,172,175,187,222,228,237],"traditional":[42],"TNM":[43],"staging":[44],"system":[45],"does":[46],"not":[47],"accurately":[48],"assess":[49],"patient's":[51],"individual":[52],"recurrence.":[55],"METHODS:":[56],"To":[57],"identify":[58],"risk-related":[60],"genetic":[61],"factors":[62],"for":[63,216,235],"CRC":[66,84,220],"after":[68],"radical":[69,87],"surgery,":[70],"we":[71],"conducted":[72],"analysis":[74],"whole-exome":[76],"sequencing":[77],"47":[79],"who":[85,254],"underwent":[86],"surgery":[88],"at":[89],"five":[90],"institutions.":[91],"Patients":[92],"were":[93],"grouped":[94],"into":[95],"non-recurrence":[96],"group":[97,110,177],"(NR,":[98],"n":[99,112],"=":[100,113,182,185],"24,":[101],"recurrence-free":[102],"survival":[103],"[RFS]":[104],">":[105],"5":[106],"years)":[107],"(R,":[111],"23,":[114],"RFS":[115,180],"<2":[116],"years).":[117],"TCGA-COAD/READ":[119,169,173],"cohort":[120],"was":[121,154,211],"employed":[122],"as":[123],"validation":[125],"dataset.":[126],"RESULTS:":[127],"A":[128],"recurrence-predictive":[129],"model":[130],"(G8plus":[131],"score)":[132],"based":[133],"on":[134],"eight":[135],"gene":[136],"(CUL9,":[137],"PCDHA12,":[138],"HECTD3,":[139],"DCX,":[140],"SMARCA2,":[141],"FAM193A,":[142],"AATK,":[143],"SORCS2)":[145],"mutations":[146],"tumor":[148],"mutation":[149],"burden/microsatellite":[150],"instability":[151],"(TMB/MSI)":[152],"status":[153],"constructed,":[155],"97.87%":[157],"accuracy":[158],"in":[159,167,218,221,241],"our":[160],"data":[161],"100%":[163],"negative":[164],"predictive":[165],"value":[166],"cohort.":[170,224],"For":[171],"cohort,":[174],"G8plus-high":[176,188],"had":[178,190],"better":[179],"(HR":[181],"0.22,":[183],"p":[184],"0.024);":[186],"tumors":[189],"significantly":[191],"more":[192],"infiltrated":[193],"immune":[194],"cell":[195],"types,":[196],"higher":[197,204],"tertiary":[198],"lymphoid":[199],"structure":[200],"signature":[201,206],"scores,":[202],"immunological":[205],"scores.":[207],"G8plus":[209,229],"score":[210,230],"also":[212],"predict":[214],"biomarker":[215,234],"immunotherapeutic":[217],"advanced":[219],"PUCH":[223],"CONCLUSIONS:":[225],"In":[226],"conclusion,":[227],"powerful":[233],"predicting":[236],"stage":[244],"CRC.":[246],"It":[247],"can":[248],"be":[249],"stratify":[252],"benefit":[255],"from":[256],"immunotherapy.":[259]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-12-20T00:00:00"}