{"id":"https://openalex.org/W4389900076","doi":"https://doi.org/10.1002/glia.24496","title":"Potassium channel modulation in macrophages sensitizes dorsal root ganglion neurons after nerve injury","display_name":"Potassium channel modulation in macrophages sensitizes dorsal root ganglion neurons after nerve injury","publication_year":2023,"publication_date":"2023-12-18","ids":{"openalex":"https://openalex.org/W4389900076","doi":"https://doi.org/10.1002/glia.24496","pmid":"https://pubmed.ncbi.nlm.nih.gov/38108588"},"language":"en","primary_location":{"id":"doi:10.1002/glia.24496","doi":"https://doi.org/10.1002/glia.24496","is_oa":true,"landing_page_url":"https://doi.org/10.1002/glia.24496","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/glia.24496","source":{"id":"https://openalex.org/S147407642","display_name":"Glia","issn_l":"0894-1491","issn":["0894-1491","1098-1136"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Glia","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/glia.24496","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083129448","display_name":"Elena A. Konnova","orcid":"https://orcid.org/0009-0005-6427-9252","observed_orcids":["https://orcid.org/0009-0005-6427-9252"]},"institutions":[{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Elena A. Konnova","raw_affiliation_strings":["Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland"],"raw_orcid":"https://orcid.org/0009-0005-6427-9252","affiliations":[{"raw_affiliation_string":"Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019042011","display_name":"Alexandru\u2010Florian Deftu","orcid":"https://orcid.org/0000-0002-2556-393X","observed_orcids":["https://orcid.org/0000-0002-2556-393X"]},"institutions":[{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Alexandru\u2010Florian Deftu","raw_affiliation_strings":["Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-2556-393X","affiliations":[{"raw_affiliation_string":"Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039163515","display_name":"Paul Chu Sin Chung","orcid":"https://orcid.org/0000-0002-0029-0947","observed_orcids":["https://orcid.org/0000-0002-0029-0947"]},"institutions":[{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Paul Chu Sin Chung","raw_affiliation_strings":["Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-0029-0947","affiliations":[{"raw_affiliation_string":"Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002760154","display_name":"Guyl\u00e8ne Kirschmann","orcid":"https://orcid.org/0000-0002-7764-2453","observed_orcids":["https://orcid.org/0000-0002-7764-2453"]},"institutions":[{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Guyl\u00e8ne Kirschmann","raw_affiliation_strings":["Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-7764-2453","affiliations":[{"raw_affiliation_string":"Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030131585","display_name":"Isabelle D\u00e9costerd","orcid":"https://orcid.org/0000-0002-4820-5289","observed_orcids":["https://orcid.org/0000-0002-4820-5289"]},"institutions":[{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I97565354","display_name":"University of Lausanne","ror":"https://ror.org/019whta54","country_code":"CH","type":"education","lineage":["https://openalex.org/I97565354"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Isabelle Decosterd","raw_affiliation_strings":["Department of Fundamental Neurosciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland","Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-4820-5289","affiliations":[{"raw_affiliation_string":"Department of Fundamental Neurosciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I97565354"]},{"raw_affiliation_string":"Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003032145","display_name":"Marc Rene Suter","orcid":"https://orcid.org/0000-0002-4653-0512","observed_orcids":["https://orcid.org/0000-0002-4653-0512"]},"institutions":[{"id":"https://openalex.org/I2802229882","display_name":"Centre Hospitalier Universitaire Vaudois","ror":"https://ror.org/05a353079","country_code":"CH","type":"healthcare","lineage":["https://openalex.org/I2802229882"]},{"id":"https://openalex.org/I97565354","display_name":"University of Lausanne","ror":"https://ror.org/019whta54","country_code":"CH","type":"education","lineage":["https://openalex.org/I97565354"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Marc R. Suter","raw_affiliation_strings":["Department of Fundamental Neurosciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland","Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland"],"raw_orcid":"https://orcid.org/0000-0002-4653-0512","affiliations":[{"raw_affiliation_string":"Department of Fundamental Neurosciences, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland","institution_ids":["https://openalex.org/I97565354"]},{"raw_affiliation_string":"Pain Center, Department of Anesthesiology, Lausanne University Hospital (CHUV), Lausanne, Switzerland","institution_ids":["https://openalex.org/I2802229882"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5003032145"],"corresponding_institution_ids":["https://openalex.org/I2802229882","https://openalex.org/I97565354"],"apc_list":{"value":4940,"currency":"USD","value_usd":4940},"apc_paid":{"value":4940,"currency":"USD","value_usd":4940},"fwci":2.3374,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.87044101,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":"72","issue":"4","first_page":"677","last_page":"691"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11204","display_name":"Ion Channels and Receptors","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2809","display_name":"Sensory Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.8289999961853027},{"id":"https://openalex.org/keywords/dorsal-root-ganglion-neurons","display_name":"dorsal root ganglion neurons","score":0.9490000009536743},{"id":"https://openalex.org/keywords/spared-nerve-injury","display_name":"spared nerve injury","score":0.6539999842643738},{"id":"https://openalex.org/keywords/kir2-1-potassium-channel","display_name":"Kir2.1 potassium channel","score":0.722000002861023},{"id":"https://openalex.org/keywords/neuronal-hyperexcitability","display_name":"neuronal hyperexcitability","score":0.8870000243186951},{"id":"https://openalex.org/keywords/neuron-glia-crosstalk","display_name":"neuron-glia crosstalk","score":0.7490000128746033},{"id":"https://openalex.org/keywords/satellite-glial-cells","display_name":"satellite glial cells","score":0.7979999780654907},{"id":"https://openalex.org/keywords/nav1-7","display_name":"Nav1.7","score":0.7940000295639038},{"id":"https://openalex.org/keywords/nav1-8","display_name":"Nav1.8","score":0.984000027179718},{"id":"https://openalex.org/keywords/voltage-gated-sodium-channels","display_name":"voltage-gated sodium channels","score":0.8080000281333923},{"id":"https://openalex.org/keywords/conditioned-medium","display_name":"conditioned medium","score":0.6159999966621399},{"id":"https://openalex.org/keywords/p38-mapk","display_name":"p38 MAPK","score":0.6050000190734863},{"id":"https://openalex.org/keywords/vesicle-exocytosis","display_name":"vesicle exocytosis","score":0.9649999737739563},{"id":"https://openalex.org/keywords/neuropathic-pain","display_name":"neuropathic pain","score":0.8040000200271606},{"id":"https://openalex.org/keywords/neuroimmune-interactions","display_name":"neuroimmune interactions","score":0.5979999899864197},{"id":"https://openalex.org/keywords/protein-trafficking","display_name":"protein trafficking","score":0.4729999899864197}],"concepts":[{"id":"https://openalex.org/C90149880","wikidata":"https://www.wikidata.org/wiki/Q1092165","display_name":"SNi","level":4,"score":0.7678954005241394},{"id":"https://openalex.org/C2776281502","wikidata":"https://www.wikidata.org/wiki/Q1395415","display_name":"Dorsal root ganglion","level":3,"score":0.6927810311317444},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.614297091960907},{"id":"https://openalex.org/C2775991916","wikidata":"https://www.wikidata.org/wiki/Q2945973","display_name":"Nerve injury","level":2,"score":0.5691297054290771},{"id":"https://openalex.org/C83743174","wikidata":"https://www.wikidata.org/wiki/Q423778","display_name":"Potassium channel","level":2,"score":0.5523310303688049},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4722793996334076},{"id":"https://openalex.org/C2778794669","wikidata":"https://www.wikidata.org/wiki/Q43054","display_name":"Neuron","level":2,"score":0.4430452287197113},{"id":"https://openalex.org/C2776880756","wikidata":"https://www.wikidata.org/wiki/Q2945973","display_name":"Peripheral nerve injury","level":3,"score":0.43097227811813354},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3910743296146393},{"id":"https://openalex.org/C2780775167","wikidata":"https://www.wikidata.org/wiki/Q9606","display_name":"Spinal cord","level":2,"score":0.2647435665130615},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.13798955082893372},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C16993767","wikidata":"https://www.wikidata.org/wiki/Q4674072","display_name":"Acid hydrolysis","level":3,"score":0.0},{"id":"https://openalex.org/C94412978","wikidata":"https://www.wikidata.org/wiki/Q103135","display_name":"Hydrolysis","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005727","descriptor_name":"Ganglia, Spinal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009457","descriptor_name":"Neuroglia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015221","descriptor_name":"Potassium Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1002/glia.24496","doi":"https://doi.org/10.1002/glia.24496","is_oa":true,"landing_page_url":"https://doi.org/10.1002/glia.24496","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/glia.24496","source":{"id":"https://openalex.org/S147407642","display_name":"Glia","issn_l":"0894-1491","issn":["0894-1491","1098-1136"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Glia","raw_type":"journal-article"},{"id":"doi:10.1101/2023.06.21.545843","doi":"https://doi.org/10.1101/2023.06.21.545843","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1101/2023.06.21.545843","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2023/06/30/2023.06.21.545843.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmid:38108588","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38108588","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Glia","raw_type":"Journal Article"},{"id":"pmh:oai:serval.unil.ch:BIB_921A4A7703A4","doi":null,"is_oa":true,"landing_page_url":"https://serval.unil.ch/notice/serval:BIB_921A4A7703A4","pdf_url":"https://serval.unil.ch/resource/serval:BIB_921A4A7703A4.P001/REF.pdf","source":{"id":"https://openalex.org/S4306401797","display_name":"SERVAL (Universit\u00e9 de Lausanne)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210093590","host_organization_name":"Swiss School of Archaeology in Greece","host_organization_lineage":["https://openalex.org/I4210093590"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Glia, vol. 72, no. 4, pp. 677-691","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.unil.ch:iris/219607","doi":null,"is_oa":false,"landing_page_url":"https://iris.unil.ch/handle/iris/219607","pdf_url":null,"source":{"id":"https://openalex.org/S7407055444","display_name":"IRIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":{"id":"doi:10.1002/glia.24496","doi":"https://doi.org/10.1002/glia.24496","is_oa":true,"landing_page_url":"https://doi.org/10.1002/glia.24496","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/glia.24496","source":{"id":"https://openalex.org/S147407642","display_name":"Glia","issn_l":"0894-1491","issn":["0894-1491","1098-1136"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Glia","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8560000061988831}],"study_designs":[],"awards":[{"id":"https://openalex.org/G837386479","display_name":null,"funder_award_id":"310030_179169/1","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G8690818240","display_name":null,"funder_award_id":"310030","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"},{"id":"https://openalex.org/G8742915410","display_name":"Activity-dependent plasticity in pathological pain","funder_award_id":"179169","funder_id":"https://openalex.org/F4320320924","funder_display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320323831","display_name":"Universit\u00e9 de Lausanne","ror":"https://ror.org/019whta54"},{"id":"https://openalex.org/F4320327235","display_name":"Servier","ror":"https://ror.org/034e7c066"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4389900076.pdf","grobid_xml":"https://content.openalex.org/works/W4389900076.grobid-xml"},"referenced_works_count":64,"referenced_works":["https://openalex.org/W42536214","https://openalex.org/W1425523120","https://openalex.org/W1496642521","https://openalex.org/W1598422965","https://openalex.org/W1608557519","https://openalex.org/W1959229569","https://openalex.org/W1968180139","https://openalex.org/W1972399884","https://openalex.org/W1985163057","https://openalex.org/W1986809710","https://openalex.org/W1988209540","https://openalex.org/W1991488724","https://openalex.org/W1996525778","https://openalex.org/W2008172360","https://openalex.org/W2036321220","https://openalex.org/W2044561802","https://openalex.org/W2047010161","https://openalex.org/W2057674925","https://openalex.org/W2077506348","https://openalex.org/W2080752012","https://openalex.org/W2087454739","https://openalex.org/W2093841866","https://openalex.org/W2101739666","https://openalex.org/W2125056253","https://openalex.org/W2133093960","https://openalex.org/W2142275367","https://openalex.org/W2143357932","https://openalex.org/W2159560463","https://openalex.org/W2161057248","https://openalex.org/W2161227647","https://openalex.org/W2178010673","https://openalex.org/W2190814680","https://openalex.org/W2196308323","https://openalex.org/W2274203202","https://openalex.org/W2320640765","https://openalex.org/W2416380723","https://openalex.org/W2528913980","https://openalex.org/W2547814918","https://openalex.org/W2621292543","https://openalex.org/W2886096965","https://openalex.org/W2891597698","https://openalex.org/W2912343418","https://openalex.org/W2981985033","https://openalex.org/W2992055484","https://openalex.org/W2996087077","https://openalex.org/W2997220739","https://openalex.org/W2999016253","https://openalex.org/W3013942217","https://openalex.org/W3044036380","https://openalex.org/W3049248883","https://openalex.org/W3084214304","https://openalex.org/W3086492786","https://openalex.org/W3088794572","https://openalex.org/W3112983604","https://openalex.org/W3136714565","https://openalex.org/W3153009118","https://openalex.org/W3208691473","https://openalex.org/W4282827828","https://openalex.org/W4292267095","https://openalex.org/W4306385735","https://openalex.org/W4308039195","https://openalex.org/W4312140308","https://openalex.org/W4320288039","https://openalex.org/W4378782445"],"related_works":["https://openalex.org/W4381489262","https://openalex.org/W7039856505","https://openalex.org/W2120011147","https://openalex.org/W1508760004","https://openalex.org/W1990116234","https://openalex.org/W2802356810","https://openalex.org/W2999016253","https://openalex.org/W4378782445","https://openalex.org/W2313452457","https://openalex.org/W1981659159"],"abstract_inverted_index":{"Abstract":[0],"Macrophages":[1],"and":[2,10,26,46,98,101,183],"satellite":[3],"glial":[4,77],"cells":[5,78],"are":[6],"found":[7],"between":[8],"injured":[9],"uninjured":[11],"neurons":[12,67,91,147],"in":[13,106,127,137,146,161,187],"the":[14,22,111,132,149,155,188],"lumbar":[15],"dorsal":[16],"root":[17],"ganglia":[18],"(DRG).":[19],"We":[20],"explored":[21],"mechanism":[23],"of":[24,32,61,113,151,190],"neuro\u2010immune":[25],"neuron\u2013glia":[27,178],"crosstalk":[28],"leading":[29],"to":[30,86,177],"hyperexcitability":[31,115,185],"DRG":[33,60,66,90,169],"neurons.":[34],"After":[35],"spared":[36],"nerve":[37,174],"injury":[38],"(SNI),":[39],"CX3CR1+":[40],"resident":[41],"macrophages":[42,107],"became":[43],"activated,":[44],"proliferated,":[45],"increased":[47,93],"inward\u2010rectifying":[48],"potassium":[49],"channel":[50,163,181],"Kir2.1":[51,105],"currents.":[52,103],"Conditioned":[53],"medium":[54],"(CM)":[55],"by":[56,172],"macrophages,":[57,170],"obtained":[58],"from":[59,68,75,116,159],"SNI":[62,109],"mice,":[63],"sensitized":[64],"small":[65],"na\u00efve":[69],"mice.":[70],"However,":[71],"treatment":[72],"with":[73,131],"CM":[74,128],"GFAP+":[76],"did":[79],"not":[80],"affect":[81],"neuronal":[82,114,141,184],"excitability.":[83],"When":[84],"subjected":[85],"this":[87],"macrophage\u2010derived":[88],"CM,":[89,152],"had":[92],"spontaneous":[94],"activity,":[95],"current\u2010evoked":[96],"responses":[97],"voltage\u2010gated":[99],"NaV1.7":[100],"NaV1.8":[102],"Silencing":[104],"after":[108],"prevented":[110,140],"induction":[112],"their":[117],"CM.":[118],"Blocking":[119,143],"vesicular":[120],"exocytosis":[121],"or":[122,129],"soluble":[123],"tumor":[124],"necrosis":[125],"factor":[126],"interfering":[130],"downstream":[133],"intracellular":[134],"p38":[135],"pathway":[136],"neurons,":[138],"also":[139],"hyperexcitability.":[142],"protein":[144],"trafficking":[145],"reduced":[148],"effect":[150],"suggesting":[153],"that":[154,168],"hyperexcitable":[156],"state":[157],"resulted":[158],"changes":[160],"NaV":[162,180],"trafficking.":[164],"These":[165],"results":[166],"suggest":[167],"primed":[171],"peripheral":[173],"injury,":[175],"contribute":[176],"crosstalk,":[179],"dysregulation":[182],"implicated":[186],"development":[189],"neuropathic":[191],"pain.":[192]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":4}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2023-12-19T00:00:00"}