{"id":"https://openalex.org/W4389730696","doi":"https://doi.org/10.1097/01.ccm.0001002348.61147.36","title":"1046: RAPID THROMBUS FORMATION AND MASSIVE PULMONARY EMBOLISM FOLLOWING CENTRAL VENOUS CATHETER PLACEMENT","display_name":"1046: RAPID THROMBUS FORMATION AND MASSIVE PULMONARY EMBOLISM FOLLOWING CENTRAL VENOUS CATHETER PLACEMENT","publication_year":2023,"publication_date":"2023-12-14","ids":{"openalex":"https://openalex.org/W4389730696","doi":"https://doi.org/10.1097/01.ccm.0001002348.61147.36"},"language":"en","primary_location":{"id":"doi:10.1097/01.ccm.0001002348.61147.36","doi":"https://doi.org/10.1097/01.ccm.0001002348.61147.36","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.ccm.0001002348.61147.36","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028386752","display_name":"Neema Jayachamarajapura Onkaramurthy","orcid":"https://orcid.org/0009-0005-9611-521X","observed_orcids":["https://orcid.org/0009-0005-9611-521X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Neema Jayachamarajapura Onkaramurthy","raw_affiliation_strings":["NYCH/H Harlem, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"NYCH/H Harlem, NY","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113071289","display_name":"Sany Kumar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sany Kumar","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046677888","display_name":"Stephen M. Pastores","orcid":"https://orcid.org/0000-0002-8850-7062","observed_orcids":["https://orcid.org/0000-0002-8850-7062"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen Pastores","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"52","issue":"1","first_page":"S495","last_page":"S495"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.8784000277519226,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":0.8784000277519226,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10641","display_name":"Central Venous Catheters and Hemodialysis","score":0.11829999834299088,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11929","display_name":"Cerebral Venous Sinus Thrombosis","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/central-venous-catheters","display_name":"central venous catheters","score":0.8119999766349792},{"id":"https://openalex.org/keywords/internal-jugular-vein-thrombosis","display_name":"internal jugular vein thrombosis","score":0.9139999747276306},{"id":"https://openalex.org/keywords/high-risk-pulmonary-embolism","display_name":"massive pulmonary embolism","score":0.9049999713897705},{"id":"https://openalex.org/keywords/retroperitoneal-leiomyosarcoma","display_name":"retroperitoneal leiomyosarcoma","score":0.8690000176429749},{"id":"https://openalex.org/keywords/perioperative-complications","display_name":"perioperative complications","score":0.7360000014305115},{"id":"https://openalex.org/keywords/point-of-care-ultrasound","display_name":"point-of-care ultrasound","score":0.9319999814033508},{"id":"https://openalex.org/keywords/heparin-anticoagulation","display_name":"heparin anticoagulation","score":0.8769999742507935},{"id":"https://openalex.org/keywords/enoxaparin","display_name":"enoxaparin","score":0.972000002861023},{"id":"https://openalex.org/keywords/factor-xa-inhibitors","display_name":"factor Xa inhibitors","score":0.7200000286102295},{"id":"https://openalex.org/keywords/right-ventricular-dysfunction","display_name":"right ventricular dysfunction","score":0.6290000081062317}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9681072235107422},{"id":"https://openalex.org/C2781362458","wikidata":"https://www.wikidata.org/wiki/Q1588755","display_name":"Thrombus","level":2,"score":0.7599566578865051},{"id":"https://openalex.org/C2776265017","wikidata":"https://www.wikidata.org/wiki/Q220570","display_name":"Pulmonary embolism","level":2,"score":0.7566038370132446},{"id":"https://openalex.org/C2778446481","wikidata":"https://www.wikidata.org/wiki/Q190404","display_name":"Central venous catheter","level":3,"score":0.6572441458702087},{"id":"https://openalex.org/C2781267111","wikidata":"https://www.wikidata.org/wiki/Q652297","display_name":"Catheter","level":2,"score":0.4761376678943634},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.37387603521347046},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3315465450286865},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.28084689378738403}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/01.ccm.0001002348.61147.36","doi":"https://doi.org/10.1097/01.ccm.0001002348.61147.36","is_oa":false,"landing_page_url":"https://doi.org/10.1097/01.ccm.0001002348.61147.36","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3036994970","https://openalex.org/W7137062446","https://openalex.org/W2335102481","https://openalex.org/W2262313280","https://openalex.org/W204439557","https://openalex.org/W1530030940","https://openalex.org/W2017164137","https://openalex.org/W3179856273","https://openalex.org/W4310672750","https://openalex.org/W2474822301"],"abstract_inverted_index":{"Introduction:":[0],"Central":[1],"venous":[2],"catheters":[3],"(CVCs)":[4],"are":[5],"often":[6],"used":[7],"for":[8,100,217],"monitoring":[9],"hemodynamic":[10],"status":[11],"and":[12,16,22,37,103,119,130,157,165,174,193,220,292,318],"rapidly":[13],"delivering":[14],"fluids":[15],"vasoactive":[17],"medications":[18],"during":[19],"the":[20,34,92,110,152,166,177,185,190,212,279,287,301,316],"peri-":[21],"postoperative":[23,107],"periods.":[24],"The":[25,160,264],"incidence":[26,57],"of":[27,59,68,134,187,203,257,282,315,320],"thrombosis":[28,49],"after":[29],"CVC":[30,73,97,161,290,317],"insertion":[31],"depends":[32],"upon":[33],"site,":[35],"duration,":[36],"underlying":[38],"patient":[39,111,167,213,265],"risk":[40],"factors":[41],"like":[42],"malignancy.":[43],"Isolated":[44],"internal":[45],"jugular":[46],"vein":[47],"(IJV)":[48],"is":[50],"a":[51,55,66,77,94,113,147,171,306],"rare":[52,280],"entity,":[53],"with":[54,84,131,154,200,231,235],"low":[56],"(0.5%)":[58],"pulmonary":[60,181],"embolism":[61],"(PE)":[62],"cases.":[63],"We":[64],"present":[65],"case":[67,277],"rapid":[69,283,313],"thrombus":[70,150,284],"formation":[71],"following":[72,289],"placement":[74,291],"resulting":[75],"in":[76,189,286,300,309],"massive":[78,298],"PE.":[79],"Description:":[80],"A":[81],"58-year-old":[82],"female":[83],"retroperitoneal":[85],"leiomyosarcoma":[86],"underwent":[87],"elective":[88],"surgical":[89,227],"resection.":[90],"For":[91],"procedure,":[93],"left":[95,148,194],"IJV":[96,149,288],"was":[98,117,162,168,209,214,233,245,266],"inserted":[99],"vascular":[101],"access":[102],"medication":[104],"administration.":[105],"On":[106,241],"day":[108],"1,":[109],"experienced":[112],"syncopal":[114],"episode.":[115],"She":[116],"alert":[118],"oriented":[120],"but":[121,211],"hypotensive":[122],"(BP":[123],"76/45":[124],"mm":[125],"Hg),":[126],"tachycardic":[127],"(HR":[128],"130/min),":[129],"oxygen":[132,141,239],"saturation":[133],"88%":[135],"on":[136,170,238,251,269],"room":[137],"air,":[138],"necessitating":[139],"2L":[140],"via":[142],"nasal":[143],"cannula.":[144],"POCUS":[145,304],"revealed":[146,254],"within":[151],"CVC,":[153],"RV":[155],"dysfunction":[156],"hyperdynamic":[158],"apex.":[159],"promptly":[163],"removed,":[164],"started":[169],"heparin":[172,232],"infusion":[173],"admitted":[175],"to":[176,224,247,295,297],"ICU.":[178],"Computed":[179],"tomography":[180],"angiography":[182],"(CTPE)":[183],"confirmed":[184],"presence":[186],"emboli":[188],"right":[191,204,258],"inter-lobar":[192],"lower":[195],"lobar":[196],"distal":[197],"segmental":[198],"branches,":[199],"possible":[201],"evidence":[202,256],"heart":[205],"strain.":[206],"Interventional":[207],"Radiology":[208],"consulted":[210],"not":[215],"suitable":[216],"catheter":[218],"thrombolysis":[219],"mechanical":[221],"thrombectomy":[222],"due":[223],"her":[225],"recent":[226],"procedure.":[228],"Anticoagulation":[229],"therapy":[230],"continued":[234],"gradual":[236],"improvement":[237],"saturation.":[240],"Day":[242,252],"4,":[243],"she":[244],"transitioned":[246],"enoxaparin.":[248],"Follow-up":[249],"CTPE":[250],"8":[253],"no":[255],"ventricular":[259],"strain,":[260],"suggesting":[261],"PE":[262,299],"resolution.":[263],"discharged":[267],"home":[268],"an":[270],"oral":[271],"factor":[272],"Xa":[273],"inhibitor.":[274],"Discussion:":[275],"Our":[276],"highlights":[278],"instance":[281],"development":[285],"its":[293],"potential":[294],"lead":[296],"perioperative":[302],"setting.":[303],"plays":[305],"crucial":[307],"role":[308],"early":[310],"diagnosis,":[311],"enabling":[312],"removal":[314],"initiation":[319],"anticoagulation":[321],"therapy.":[322]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-12-15T00:00:00"}