{"id":"https://openalex.org/W4389218992","doi":"https://doi.org/10.1182/blood-2023-190765","title":"Frequency of Geriatric Evaluation and Results in the Treatment of the Patient with Hematological Malignancy","display_name":"Frequency of Geriatric Evaluation and Results in the Treatment of the Patient with Hematological Malignancy","publication_year":2023,"publication_date":"2023-11-02","ids":{"openalex":"https://openalex.org/W4389218992","doi":"https://doi.org/10.1182/blood-2023-190765"},"language":"en","primary_location":{"id":"doi:10.1182/blood-2023-190765","doi":"https://doi.org/10.1182/blood-2023-190765","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1182/blood-2023-190765","pdf_url":"https://ashpublications.org/blood/article-pdf/142/Supplement 1/6315/2191270/blood-2912-main.pdf","source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ashpublications.org/blood/article-pdf/142/Supplement 1/6315/2191270/blood-2912-main.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Carlos Cruz Castillo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Carlos Cruz Castillo","raw_affiliation_strings":["1Departament of Hematology, Institute National of Cancerology, M\u00e9xico, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Departament of Hematology, Institute National of Cancerology, M\u00e9xico, Mexico","institution_ids":["https://openalex.org/I4210153971"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086514291","display_name":"Brenda L. Acosta\u2010Maldonado","orcid":"https://orcid.org/0000-0003-4692-0710","observed_orcids":["https://orcid.org/0000-0003-4692-0710"]},"institutions":[{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Brenda Lizeth Acosta Maldonado","raw_affiliation_strings":["2Departament of Hematology, Institute National of Cancerology, Mexico, Mexico"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Departament of Hematology, Institute National of Cancerology, Mexico, Mexico","institution_ids":["https://openalex.org/I4210153971"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064039730","display_name":"Silvia Rivas-Vera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210153971","display_name":"Instituto Nacional de Cancerolog\u00eda","ror":"https://ror.org/04z3afh10","country_code":"MX","type":"government","lineage":["https://openalex.org/I4210095685","https://openalex.org/I4210153971"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Silvia Rivas-Vera","raw_affiliation_strings":["3Departament of Hematology, Instituto Nacional Cancerologia, Mexico City, MEX"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"3Departament of Hematology, Instituto Nacional Cancerologia, Mexico City, MEX","institution_ids":["https://openalex.org/I4210153971"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210153971"],"apc_list":{"value":5000,"currency":"USD","value_usd":5000},"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"142","issue":"Supplement 1","first_page":"6315","last_page":"6315"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11011","display_name":"Frailty in Older Adults","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10496","display_name":"Pharmaceutical Practices and Patient Outcomes","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2717","display_name":"Geriatrics and Gerontology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/geriatric-assessment","display_name":"geriatric assessment","score":0.949999988079071},{"id":"https://openalex.org/keywords/hematologic-malignancies","display_name":"hematologic malignancies","score":0.9120000004768372},{"id":"https://openalex.org/keywords/older-adults","display_name":"older adults","score":0.8169999718666077},{"id":"https://openalex.org/keywords/chemotherapy","display_name":"chemotherapy","score":0.5559999942779541},{"id":"https://openalex.org/keywords/non-hodgkin-lymphoma","display_name":"non-Hodgkin lymphoma","score":0.8370000123977661},{"id":"https://openalex.org/keywords/diffuse-large-b-cell-lymphoma","display_name":"diffuse large B-cell lymphoma","score":0.8970000147819519},{"id":"https://openalex.org/keywords/multiple-myeloma","display_name":"multiple myeloma","score":0.7279999852180481},{"id":"https://openalex.org/keywords/frailty","display_name":"frailty","score":0.7450000047683716},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.7670000195503235},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.640999972820282},{"id":"https://openalex.org/keywords/treatment-related-toxicity","display_name":"treatment toxicity","score":0.5429999828338623},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.5979999899864197},{"id":"https://openalex.org/keywords/quality-of-life-after-treatment","display_name":"quality of life after treatment","score":0.36899998784065247}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8791412711143494},{"id":"https://openalex.org/C2777319248","wikidata":"https://www.wikidata.org/wiki/Q5550843","display_name":"Geriatric oncology","level":3,"score":0.6414543390274048},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.5694580078125},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.5487651228904724},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5388410091400146},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5018565654754639},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5008759498596191},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4839392304420471},{"id":"https://openalex.org/C54183767","wikidata":"https://www.wikidata.org/wiki/Q10384","display_name":"Geriatrics","level":2,"score":0.4624254107475281},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.4490528702735901},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.43364253640174866},{"id":"https://openalex.org/C27415008","wikidata":"https://www.wikidata.org/wiki/Q7256382","display_name":"Psychological intervention","level":2,"score":0.4234634041786194},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.32010337710380554},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1182/blood-2023-190765","doi":"https://doi.org/10.1182/blood-2023-190765","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1182/blood-2023-190765","pdf_url":"https://ashpublications.org/blood/article-pdf/142/Supplement 1/6315/2191270/blood-2912-main.pdf","source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1182/blood-2023-190765","doi":"https://doi.org/10.1182/blood-2023-190765","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1182/blood-2023-190765","pdf_url":"https://ashpublications.org/blood/article-pdf/142/Supplement 1/6315/2191270/blood-2912-main.pdf","source":{"id":"https://openalex.org/S200071133","display_name":"Blood","issn_l":"0006-4971","issn":["0006-4971","1528-0020"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Blood","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4389218992.pdf","grobid_xml":"https://content.openalex.org/works/W4389218992.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4386750203","https://openalex.org/W2946096511","https://openalex.org/W3025977118","https://openalex.org/W2062946371","https://openalex.org/W4200061775","https://openalex.org/W4398770502","https://openalex.org/W4310161880","https://openalex.org/W3032740699","https://openalex.org/W4240319536","https://openalex.org/W3096335768"],"abstract_inverted_index":{"Introduction:":[0],"Hematologic":[1],"malignancies":[2],"(HM)":[3],"are":[4,29,37,73,77,102,144,521],"a":[5,90,140,232,288,613,621,645],"diverse":[6,12],"group":[7,57],"of":[8,34,44,48,58,86,107,114,126,159,181,204,229,234,250,373,390,431,450,465,592,595,602,631],"blood":[9],"cancers":[10],"with":[11,31,79,99,135,186,197,218,231,287,364,401,407,488,561,586,640],"etiologies,":[13],"incidence,":[14],"prognosis,":[15],"and":[16,46,71,95,152,183,188,207,298,342,371,379,385,411,424,455,494,510,534,551],"survival.":[17],"HM":[18],"represents":[19],"the":[20,35,105,150,153,161,165,202,224,247,263,267,278,292,299,439,443,448,458,470,474,629],"fourth":[21],"most":[22,349],"common":[23],"malignancy;":[24],"approximately":[25],"1.29":[26],"million":[27],"people":[28,40],"living":[30],"HM.":[32,219],"Half":[33],"cases":[36],"diagnosed":[38],"in":[39,52,120,156,210,215,266,291,315,320,325,330,335,340,345,382,418,422,426,442,473,486,507,514,559,573,584],"over":[41],"65":[42,238],"years":[43,239,306],"age,":[45,100],"70%":[47],"cancer":[49,136,641],"deaths":[50],"occur":[51],"this":[53,121],"same":[54],"population.":[55,122],"This":[56],"patients":[59,88,187,196,217,230,286,362,560,574],"is":[60,89,111,163,479,545,564,569,581,608,625],"more":[61,503,570],"vulnerable,":[62],"which":[63,101,160,452,619],"complicates":[64],"their":[65],"care.":[66],"Cognitive":[67],"impairment,":[68],"functional":[69],"dependence,":[70],"frailty":[72],"frequent":[74],"factors;":[75],"they":[76],"associated":[78,98],"greater":[80],"toxicity":[81],"to":[82,93,104,254,353,377,438,447,469,588],"treatment.":[83],"The":[84,123,310,348,369,388,429,463,482,499],"management":[85,116,630],"these":[87,191],"challenge":[91],"due":[92],"comorbidities":[94],"physiological":[96],"changes":[97],"relationed":[103],"risk":[106,372,381],"treatment":[108,177,214,245,432,466,478],"complications.":[109],"There":[110,143],"little":[112],"evidence":[113],"clinical":[115,169,227,589],"guidelines":[117],"for":[118,273,403,409,457,618,628],"decision-making":[119,211],"American":[124],"Society":[125],"Clinical":[127],"Oncology":[128],"(ASCO)":[129],"recommends":[130],"that":[131,172,501,636],"all":[132,518,637],"older":[133,241,638],"adults":[134,639],"receiving":[137,642],"chemotherapy":[138,213,417,568,596,643],"have":[139,243,644],"geriatric":[141,154,173,205,216,391,444,475,558,623,632,646],"evaluation.":[142,647],"recommended":[145],"evaluation":[146,155,206,392,445,476],"scales,":[147],"such":[148],"as":[149],"G8":[151],"hematology":[157],"(GEH),":[158],"latter":[162],"considered":[164,626],"gold":[166],"standard.":[167],"Recent":[168],"trials":[170,192],"suggest":[171],"assessment-guided":[174],"interventions":[175],"reduce":[176],"toxicity,":[178],"improve":[179,184],"quality":[180],"life,":[182],"communication":[185],"caregivers.":[189],"Unfortunately,":[190],"were":[193,296,312,453,505],"conducted":[194],"on":[195],"solid":[198],"tumors.":[199],"Aim":[200],"Describe":[201],"frequency":[203,389,430,464],"its":[208],"value":[209],"regarding":[212],"Methods:":[220],"We":[221,283,634],"retrospectively":[222],"reviewed":[223],"data":[225],"from":[226,252],"records":[228],"diagnosis":[233,290,303,375],"hematological":[235,289,374,562],"malignancy":[236,563],"aged":[237],"or":[240,492,598,600],"who":[242],"received":[244],"at":[246,302,358,365,396,542,547,552],"National":[248],"Institute":[249],"Cancerology":[251],"2018":[253],"2022.":[255],"An":[256],"overall":[257,528],"survival":[258,529,541],"analysis":[259],"was":[260,304,393,434,460,484,524,531,538],"performed":[261],"using":[262,277],"methodology":[264],"described":[265],"Kaplan":[268],"-":[269],"Meier":[270],"method,":[271],"looking":[272],"differences":[274],"between":[275],"groups":[276],"log":[279],"rank":[280],"test.":[281],"Results:":[282],"analyzed":[284],"405":[285],"elderly;":[293],"52":[294],"%":[295,384,395,400,406,413,490,496,509],"women,":[297],"median":[300,527],"age":[301],"72":[305],"(range":[307],"65-92":[308],"years).":[309],"diagnoses":[311],"non-Hodgkin":[313],"lymphoma":[314,324,351,357],"71":[316],"%,":[317,322,327,332,337,420,436],"multiple":[318],"myeloma":[319],"14":[321],"Hodgkin":[323],"6":[326],"acute":[328],"leukemia":[329],"4":[331,427],"myeloprolipherative":[333],"neoplasm":[334,339,344],"2":[336,548],"lymphoproliferative":[338],"2.2%,":[341],"myelodysplasia":[343],"1.5":[346],"%.":[347,360,428,462,481,516,566],"prevalent":[350],"corresponds":[352],"diffuse":[354],"large":[355],"B-cell":[356],"66.7":[359],"All":[361],"(62.4%)":[363],"least":[366],"one":[367],"comorbidity.":[368],"stratification":[370],"correspond":[376],"advanced":[378],"high":[380],"74.6":[383],"65.4%,":[386],"respectively.":[387],"10.6":[394,565],"diagnosis.":[397],"Considered":[398],"15.6":[399],"fragility":[402,408],"geriatricians,":[404],"39":[405],"hematologists,":[410],"45.4":[412],"non-fragility.":[414],"Received":[415],"intensive":[416],"59":[419],"adjusted":[421],"34%,":[423],"palliative":[425],"modification":[433,456],"14.8":[435],"according":[437,468],"recommendations":[440,471],"issued":[441,472],"prior":[446],"start":[449],"treatment,":[451],"4.9%,":[454],"hematologist":[459],"60":[461,525],"modifications":[467],"during":[477],"40":[480],"response":[483],"complete":[485],"58%,":[487,550],"31":[489],"relapse":[491],"progression":[493],"10":[495],"partial":[497],"response.":[498],"complications":[500,603],"occurred":[502],"frequently":[504,571],"sepsis":[506],"64":[508],"SARS":[511],"COV-2":[512],"infection":[513],"13":[515],"Of":[517],"patients,":[519],"52.5%":[520],"alive":[522],"(follow-up":[523],"months),":[526],"(OS)":[530],"27.4":[532],"months,":[533],"treatment-related":[535],"mortality":[536],"(TRM)":[537],"9.4%.":[539],"Overall":[540],"1":[543],"year":[544],"82%,":[546],"years,":[549,554,578],"3":[553],"27%.":[555],"Conclusions:":[556],"Assessment":[557],"Intensive":[567],"administered":[572],"younger":[575],"than":[576],"75":[577],"but":[579],"there":[580],"no":[582],"difference":[583],"OS":[585,607],"respect":[587],"stage,":[590],"presence":[591,601],"comorbidities,":[593],"type":[594],"(intensive":[597],"adjusted),":[599],"(p":[604,615],"\u2265":[605],"0,05).":[606],"better":[609],"when":[610],"evaluated":[611],"by":[612],"geriatrician":[614],"=":[616],"0,000),":[617],"reason":[620],"comprehensive":[622],"assessment":[624],"important":[627],"patients.":[633],"recommend":[635]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-12-02T00:00:00"}