{"id":"https://openalex.org/W4389101922","doi":"https://doi.org/10.1109/sensors56945.2023.10325264","title":"CRISPR-Based Diagnostic for In-Field Detection of Plant Pathogens","display_name":"CRISPR-Based Diagnostic for In-Field Detection of Plant Pathogens","publication_year":2023,"publication_date":"2023-10-29","ids":{"openalex":"https://openalex.org/W4389101922","doi":"https://doi.org/10.1109/sensors56945.2023.10325264"},"language":"en","primary_location":{"id":"doi:10.1109/sensors56945.2023.10325264","doi":"https://doi.org/10.1109/sensors56945.2023.10325264","is_oa":false,"landing_page_url":"https://doi.org/10.1109/sensors56945.2023.10325264","pdf_url":null,"source":{"id":"https://openalex.org/S4210192710","display_name":"Proceedings of IEEE Sensors/Proceedings of IEEE Sensors ...","issn_l":"1930-0395","issn":["1930-0395","2168-9229","2168-9237"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE SENSORS","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113056943","display_name":"Amy Heathcote","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Amy Heathcote","raw_affiliation_strings":["University of Toronto,Department of Chemical Engineering and Applied Chemistry,Toronto,Canada","Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Toronto,Department of Chemical Engineering and Applied Chemistry,Toronto,Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055266752","display_name":"Nicole E. Weckman","orcid":"https://orcid.org/0000-0001-5894-4926","observed_orcids":["https://orcid.org/0000-0001-5894-4926"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Nicole E Weckman","raw_affiliation_strings":["University of Toronto,Department of Chemical Engineering and Applied Chemistry,Toronto,Canada","Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada","Institute for Studies in Transdisciplinary Engineering, Education & Practice, University of Toronto, Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Toronto,Department of Chemical Engineering and Applied Chemistry,Toronto,Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Department of Chemical Engineering and Applied Chemistry, University of Toronto, Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Institute for Studies in Transdisciplinary Engineering, Education & Practice, University of Toronto, Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I185261750"],"apc_list":null,"apc_paid":null,"fwci":0.4692,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.61299867,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":93},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"4"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.6366999745368958,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11393","display_name":"Biosensors and Analytical Detection","score":0.6366999745368958,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10878","display_name":"CRISPR and Genetic Engineering","score":0.3100999891757965,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10825","display_name":"Plant Pathogens and Fungal Diseases","score":0.013899999670684338,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crispr-based-diagnostics","display_name":"CRISPR-based diagnostics","score":0.9440000057220459},{"id":"https://openalex.org/keywords/plant-pathogenic-fungi","display_name":"plant pathogenic fungi","score":0.953000009059906},{"id":"https://openalex.org/keywords/colletotrichum-coccodes","display_name":"Colletotrichum coccodes","score":0.996999979019165},{"id":"https://openalex.org/keywords/soilborne-fungi","display_name":"soil-borne fungi","score":0.8880000114440918},{"id":"https://openalex.org/keywords/grna-design","display_name":"sgRNA design","score":0.871999979019165},{"id":"https://openalex.org/keywords/fungicide-reduction","display_name":"fungicide reduction","score":0.6880000233650208},{"id":"https://openalex.org/keywords/resource-limited-settings","display_name":"resource-limited settings","score":0.7929999828338623}],"concepts":[{"id":"https://openalex.org/C98108389","wikidata":"https://www.wikidata.org/wiki/Q412563","display_name":"CRISPR","level":3,"score":0.7209004759788513},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5623494982719421},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.49566781520843506},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4139004647731781},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.06581071019172668},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/sensors56945.2023.10325264","doi":"https://doi.org/10.1109/sensors56945.2023.10325264","is_oa":false,"landing_page_url":"https://doi.org/10.1109/sensors56945.2023.10325264","pdf_url":null,"source":{"id":"https://openalex.org/S4210192710","display_name":"Proceedings of IEEE Sensors/Proceedings of IEEE Sensors ...","issn_l":"1930-0395","issn":["1930-0395","2168-9229","2168-9237"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1"],"host_organization":"https://openalex.org/P4310319808","host_organization_name":"Institute of Electrical and Electronics Engineers","host_organization_lineage":["https://openalex.org/P4310319808"],"host_organization_lineage_names":["Institute of Electrical and Electronics Engineers"],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2023 IEEE SENSORS","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.9208999872207642,"display_name":"Zero hunger"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W13650813","https://openalex.org/W1989433267","https://openalex.org/W1991383909","https://openalex.org/W1993125875","https://openalex.org/W2002489582","https://openalex.org/W2010125704","https://openalex.org/W2023351271","https://openalex.org/W2065806817","https://openalex.org/W2128028173","https://openalex.org/W2160378127","https://openalex.org/W2412194679","https://openalex.org/W2771595483","https://openalex.org/W2785904295","https://openalex.org/W2790605248","https://openalex.org/W2945347896","https://openalex.org/W3015704482","https://openalex.org/W3087209706","https://openalex.org/W3157368896","https://openalex.org/W3178418858","https://openalex.org/W3189188210","https://openalex.org/W3206885372","https://openalex.org/W4220972968","https://openalex.org/W4223425405","https://openalex.org/W4226080101","https://openalex.org/W4285045601","https://openalex.org/W4286296872","https://openalex.org/W4377940145"],"related_works":["https://openalex.org/W7220688688","https://openalex.org/W4414806944","https://openalex.org/W4412551789","https://openalex.org/W4413989169","https://openalex.org/W4395465347","https://openalex.org/W7127889078","https://openalex.org/W4408058252","https://openalex.org/W4407547267","https://openalex.org/W4306790310","https://openalex.org/W4385332381"],"abstract_inverted_index":{"Plant":[0],"fungal":[1,36,142],"pathogens":[2,143],"are":[3,46,123],"an":[4,54],"increasingly":[5],"common":[6],"and":[7,17,33,43,59,95,112,138],"costly":[8],"threat":[9],"to":[10,84,118,144],"agricultural":[11,134,148],"yields,":[12],"resulting":[13],"in":[14,38,63,133],"wasted":[15],"produce":[16],"the":[18,68,76,85,92],"frequent":[19],"use":[20,27],"of":[21,28,71,87,99,114,141],"fungicides.":[22],"To":[23],"enable":[24,145],"more":[25],"targeted":[26],"fungicides,":[29],"methods":[30],"for":[31,57,75,102,127,136],"detecting":[32],"identifying":[34],"plant":[35],"infections":[37],"a":[39,72],"rapid,":[40],"low-cost,":[41],"decentralized,":[42],"power-free":[44],"manner":[45],"needed.":[47],"CRISPR-based":[48,73],"diagnostics":[49],"have":[50],"recently":[51],"emerged":[52],"as":[53],"effective":[55],"tool":[56],"sensitive":[58],"specific":[60],"pathogen":[61],"detection":[62,113,140],"resource-limited":[64],"settings.":[65],"We":[66],"present":[67],"preliminary":[69],"designs":[70],"diagnostic":[74,126],"soil-borne":[77],"fungus":[78],"Colletotrichum":[79],"coccodes.":[80],"Bioinformatics":[81],"analysis":[82],"led":[83],"identification":[86],"four":[88],"gRNA":[89,108],"candidates":[90],"targeting":[91],"ITS":[93,96],"1":[94],"2":[97],"regions":[98],"C.":[100,128],"coccodes":[101,129],"high":[103],"specificity.":[104],"The":[105],"most":[106],"promising":[107],"was":[109],"further":[110],"screened":[111],"DNA":[115],"concentrations":[116],"down":[117],"500":[119],"pM":[120],"without":[121],"amplification":[122],"shown.":[124],"This":[125],"could":[130],"be":[131],"used":[132],"settings":[135],"rapid":[137],"cost-effective":[139],"high-yield":[146],"sustainable":[147],"practices.":[149]},"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2023-11-29T00:00:00"}