{"id":"https://openalex.org/W4389029328","doi":"https://doi.org/10.1093/ofid/ofad500.1658","title":"1829. The Impact of Social Determinants of Health on Treatment Route, Duration, and Outcomes in Bone and Joint Infections","display_name":"1829. The Impact of Social Determinants of Health on Treatment Route, Duration, and Outcomes in Bone and Joint Infections","publication_year":2023,"publication_date":"2023-11-27","ids":{"openalex":"https://openalex.org/W4389029328","doi":"https://doi.org/10.1093/ofid/ofad500.1658","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10677009"},"language":"en","primary_location":{"id":"doi:10.1093/ofid/ofad500.1658","doi":"https://doi.org/10.1093/ofid/ofad500.1658","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ofid/ofad500.1658","pdf_url":"https://academic.oup.com/ofid/article-pdf/10/Supplement_2/ofad500.1658/53767616/ofad500.1658.pdf","source":{"id":"https://openalex.org/S2735126445","display_name":"Open Forum Infectious Diseases","issn_l":"2328-8957","issn":["2328-8957"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/ofid/article-pdf/10/Supplement_2/ofad500.1658/53767616/ofad500.1658.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017710494","display_name":"Heather Cummins","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heather Cummins","raw_affiliation_strings":["University of Utah School of Medicine , Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Utah School of Medicine , Salt Lake City, Utah","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040265515","display_name":"Chanah Gallagher","orcid":"https://orcid.org/0000-0003-4247-3546","observed_orcids":["https://orcid.org/0000-0003-4247-3546"]},"institutions":[{"id":"https://openalex.org/I2802654978","display_name":"The Medical Center of Aurora","ror":"https://ror.org/04qw37741","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802654978","https://openalex.org/I4210120438"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chanah Gallagher","raw_affiliation_strings":["The Medical Center of Aurora , Aurora, Colorado"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Medical Center of Aurora , Aurora, Colorado","institution_ids":["https://openalex.org/I2802654978"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Julie Gray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Julie Gray","raw_affiliation_strings":["University of Utah , Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Utah , Salt Lake City, Utah","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028250966","display_name":"Russell J Benefield","orcid":"https://orcid.org/0000-0002-3235-6285","observed_orcids":["https://orcid.org/0000-0002-3235-6285"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]},{"id":"https://openalex.org/I4210148268","display_name":"University of Utah Health Care","ror":"https://ror.org/047s7ex42","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210148268"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Russell J Benefield","raw_affiliation_strings":["University of Utah Health , Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Utah Health , Salt Lake City, Utah","institution_ids":["https://openalex.org/I223532165","https://openalex.org/I4210148268"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5064431156","display_name":"Laura Certain","orcid":"https://orcid.org/0000-0002-2991-125X","observed_orcids":["https://orcid.org/0000-0002-2991-125X"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laura Certain","raw_affiliation_strings":["University of Utah , Salt Lake City, Utah"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Utah , Salt Lake City, Utah","institution_ids":["https://openalex.org/I223532165"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3676,"currency":"USD","value_usd":3676},"apc_paid":{"value":3676,"currency":"USD","value_usd":3676},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"10","issue":"Supplement_2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11293","display_name":"Orthopedic Infections and Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11293","display_name":"Orthopedic Infections and Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11381","display_name":"Infectious Diseases and Tuberculosis","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/social-determinants-of-health","display_name":"social determinants of health","score":0.9959999918937683},{"id":"https://openalex.org/keywords/bone-and-joint-infections","display_name":"bone and joint infections","score":0.9470000267028809},{"id":"https://openalex.org/keywords/osteomyelitis","display_name":"osteomyelitis","score":0.843999981880188},{"id":"https://openalex.org/keywords/oral-versus-intravenous-antibiotics","display_name":"oral versus intravenous antibiotics","score":0.7319999933242798},{"id":"https://openalex.org/keywords/vancomycin","display_name":"vancomycin","score":0.8370000123977661},{"id":"https://openalex.org/keywords/medicaid","display_name":"Medicaid","score":0.7620000243186951},{"id":"https://openalex.org/keywords/treatment-failure","display_name":"treatment failure","score":0.968999981880188},{"id":"https://openalex.org/keywords/homelessness","display_name":"homelessness","score":0.43799999356269836},{"id":"https://openalex.org/keywords/injection-drug-use","display_name":"intravenous drug use","score":0.968999981880188},{"id":"https://openalex.org/keywords/racial-and-ethnic-disparities","display_name":"racial and ethnic disparities","score":0.7289999723434448},{"id":"https://openalex.org/keywords/insurance-status","display_name":"insurance status","score":0.6190000176429749},{"id":"https://openalex.org/keywords/primary-language","display_name":"primary language","score":0.48399999737739563}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.904231607913971},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.5788185596466064},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5770289897918701},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4855658710002899},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4168423116207123},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3929322361946106},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1093/ofid/ofad500.1658","doi":"https://doi.org/10.1093/ofid/ofad500.1658","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ofid/ofad500.1658","pdf_url":"https://academic.oup.com/ofid/article-pdf/10/Supplement_2/ofad500.1658/53767616/ofad500.1658.pdf","source":{"id":"https://openalex.org/S2735126445","display_name":"Open Forum Infectious Diseases","issn_l":"2328-8957","issn":["2328-8957"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infectious Diseases","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10677009","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10677009","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10677009/pdf/ofad500.1658.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infect Dis","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/ofid/ofad500.1658","doi":"https://doi.org/10.1093/ofid/ofad500.1658","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ofid/ofad500.1658","pdf_url":"https://academic.oup.com/ofid/article-pdf/10/Supplement_2/ofad500.1658/53767616/ofad500.1658.pdf","source":{"id":"https://openalex.org/S2735126445","display_name":"Open Forum Infectious Diseases","issn_l":"2328-8957","issn":["2328-8957"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infectious Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0},{"display_name":"Reduced inequalities","id":"https://metadata.un.org/sdg/10","score":0.5676000118255615}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4389029328.pdf","grobid_xml":"https://content.openalex.org/works/W4389029328.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4200227347","https://openalex.org/W2966083096","https://openalex.org/W2215744541","https://openalex.org/W2794784072","https://openalex.org/W3086784454","https://openalex.org/W2994879298","https://openalex.org/W4414128537","https://openalex.org/W7136140991","https://openalex.org/W4282011463","https://openalex.org/W4389030489"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"The":[2,154,294],"Oral":[3],"versus":[4],"Intravenous":[5],"Antibiotics":[6],"for":[7,25,83,198],"Bone":[8],"and":[9,58,63,79,87,99,110,125,150,185,263,297,329],"Joint":[10],"Infection":[11],"(OVIVA)":[12],"trial":[13],"concluded":[14],"that":[15],"oral":[16],"antibiotic":[17,23,292],"therapy":[18,24],"was":[19,157,202],"noninferior":[20],"to":[21,69,165,207,226,235,243,252,275,299,322],"intravenous":[22,146],"complex":[26],"orthopedic":[27],"infections.":[28,65,89],"Similar":[29],"studies":[30],"have":[31],"confirmed":[32],"the":[33,43,130,158,199],"OVIVA":[34],"trials":[35],"findings.":[36],"However,":[37,278],"there":[38],"is":[39,320],"limited":[40],"information":[41],"regarding":[42,53],"impact":[44,325],"of":[45,48,61,132,145,152,160,177,180,187,209,214,232,285,317],"Social":[46],"Determinants":[47],"Health":[49],"(SDOH)":[50],"on":[51,119,238,247,280,326],"decisions":[52],"IV":[54,74,120,164,239,274],"vs.":[55,75],"PO":[56,76,166,227,276,300],"treatment":[57,59,77,81,188,254,286,327],"outcomes":[60,82,173],"bone":[62,86,109,262],"joint":[64,88,111,264],"This":[66],"study":[67,306],"aimed":[68],"determine":[70],"how":[71],"SDOH":[72,137,266,296,319],"affect":[73],"choices":[78],"overall":[80],"patients":[84,95,106,161,194,222,236,260,279],"with":[85,183,205,261,270,311],"Methods":[90],"In":[91],"this":[92],"single-center":[93],"cohort,":[94],"discharged":[96,118],"between":[97],"4/1/2018":[98],"4/1/2022":[100],"were":[101,105,224,249,267,302],"examined.":[102],"Inclusion":[103],"criteria":[104,197],"who":[107,223],"had":[108],"infections,":[112,265],"inpatient":[113],"Infectious":[114,134],"Disease":[115,135],"(ID)":[116],"consult,":[117],"vancomycin,":[121],"age":[122],">18":[123],"years,":[124],"scheduled":[126],"follow":[127,181],"up":[128,182],"in":[129,221,291],"University":[131],"Utah":[133],"Clinic.":[136],"assessed":[138],"included":[139,174],"primary":[140,155,211],"language,":[141,212],"race/ethnicity,":[142],"insurance,":[143],"history":[144,151,208,213],"drug":[147],"use":[148],"(IVDU),":[149],"homelessness.":[153],"outcome":[156],"number":[159],"switched":[162,225],"from":[163,273],"antibiotics":[167,228],"two":[168,230],"weeks":[169,231],"after":[170],"discharge.":[171],"Secondary":[172],"total":[175],"duration":[176,179],"antibiotics,":[178],"ID,":[184,339],"rate":[186],"failure.":[189],"Results":[190],"Two":[191],"hundred":[192],"seventy-seven":[193],"met":[195],"inclusion":[196],"cohort.":[200],"There":[201],"no":[203,289],"difference":[204,290],"respect":[206,242],"homelessness,":[210],"IVDU,":[215],"race,":[216],"ethnicity,":[217],"or":[218],"insurance":[219],"status":[220],"within":[229],"discharge":[233],"compared":[234],"maintained":[237],"antibiotics.":[240,277],"With":[241],"secondary":[244],"outcomes,":[245],"individuals":[246],"Medicaid":[248,281],"more":[250],"likely":[251],"experience":[253],"failure":[255,287,328],"(Table":[256],"1B).":[257],"Conclusion":[258],"For":[259],"not":[268],"associated":[269],"a":[271],"switch":[272],"experienced":[282],"higher":[283],"rates":[284],"despite":[288],"route.":[293],"examined":[295],"transition":[298],"regimens":[301],"infrequently":[303],"observed":[304],"among":[305],"participants":[307],"which":[308],"created":[309],"difficulty":[310],"drawing":[312],"further":[313],"conclusions.":[314],"Further":[315],"examination":[316],"these":[318],"important":[321],"understand":[323],"their":[324],"improve":[330],"patient":[331],"care.":[332],"Disclosures":[333],"Russell":[334],"J.":[335],"Benefield,":[336],"PharmD,":[337],"BCPS-AQ":[338],"Paratek":[340],"Pharmaceuticals:":[341],"Grant/Research":[342],"Support":[343]},"counts_by_year":[],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2023-11-27T00:00:00"}