{"id":"https://openalex.org/W4389029306","doi":"https://doi.org/10.1093/ofid/ofad500.1875","title":"2253. Hospitalist Antibiotic Prescribing Patterns by Hour and Weekday","display_name":"2253. Hospitalist Antibiotic Prescribing Patterns by Hour and Weekday","publication_year":2023,"publication_date":"2023-11-27","ids":{"openalex":"https://openalex.org/W4389029306","doi":"https://doi.org/10.1093/ofid/ofad500.1875"},"language":"en","primary_location":{"id":"doi:10.1093/ofid/ofad500.1875","doi":"https://doi.org/10.1093/ofid/ofad500.1875","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ofid/ofad500.1875","pdf_url":"https://academic.oup.com/ofid/article-pdf/10/Supplement_2/ofad500.1875/53771764/ofad500.1875.pdf","source":{"id":"https://openalex.org/S2735126445","display_name":"Open Forum Infectious Diseases","issn_l":"2328-8957","issn":["2328-8957"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infectious Diseases","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/ofid/article-pdf/10/Supplement_2/ofad500.1875/53771764/ofad500.1875.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084104881","display_name":"Joshua H Gray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210144876","display_name":"Duke University Health System","ror":"https://ror.org/03wfqwh68","country_code":"US","type":"education","lineage":["https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua H Gray","raw_affiliation_strings":["Duke University Health System , Durham, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Health System , Durham, North Carolina","institution_ids":["https://openalex.org/I4210144876"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068076223","display_name":"Lana Wahid","orcid":"https://orcid.org/0000-0002-2160-3287","observed_orcids":["https://orcid.org/0000-0002-2160-3287"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lana Wahid","raw_affiliation_strings":["Duke University School of Medicine , Durham, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University School of Medicine , Durham, North Carolina","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072859943","display_name":"Rebekah W. Moehring","orcid":"https://orcid.org/0000-0001-7741-6029","observed_orcids":["https://orcid.org/0000-0001-7741-6029"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rebekah W Moehring","raw_affiliation_strings":["Duke University , Durham, NC"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University , Durham, NC","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087823054","display_name":"Michael Edwards Yarrington","orcid":"https://orcid.org/0000-0003-3186-1519","observed_orcids":["https://orcid.org/0000-0003-3186-1519"]},"institutions":[{"id":"https://openalex.org/I4210144876","display_name":"Duke University Health System","ror":"https://ror.org/03wfqwh68","country_code":"US","type":"education","lineage":["https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael E Yarrington","raw_affiliation_strings":["Duke University Health System , Durham, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Duke University Health System , Durham, North Carolina","institution_ids":["https://openalex.org/I4210144876"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3676,"currency":"USD","value_usd":3676},"apc_paid":{"value":3676,"currency":"USD","value_usd":3676},"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.18984082,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"10","issue":"Supplement_2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10897","display_name":"Antibiotic Use and Resistance","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12174","display_name":"Hospital Admissions and Outcomes","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hospitalists","display_name":"hospitalists","score":0.8100000023841858},{"id":"https://openalex.org/keywords/antibiotic-prescribing","display_name":"antibiotic prescribing","score":0.8679999709129333},{"id":"https://openalex.org/keywords/antibiotic-escalation","display_name":"antibiotic escalation","score":0.9070000052452087},{"id":"https://openalex.org/keywords/antibiotic-initiation","display_name":"antibiotic initiation","score":0.8140000104904175},{"id":"https://openalex.org/keywords/night-shift-work","display_name":"night shift work","score":0.6140000224113464},{"id":"https://openalex.org/keywords/antimicrobial-stewardship","display_name":"antimicrobial stewardship","score":0.7519999742507935},{"id":"https://openalex.org/keywords/nosocomial-infections","display_name":"nosocomial infections","score":0.5550000071525574},{"id":"https://openalex.org/keywords/timing-of-antibiotic-administration","display_name":"timing of antibiotic administration","score":0.4749999940395355},{"id":"https://openalex.org/keywords/quality-of-hospital-care","display_name":"hospital quality of care","score":0.33399999141693115},{"id":"https://openalex.org/keywords/patient-safety","display_name":"patient safety","score":0.4169999957084656},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.4779999852180481},{"id":"https://openalex.org/keywords/in-hospital-mortality","display_name":"in-hospital mortality","score":0.42100000381469727},{"id":"https://openalex.org/keywords/hospitalization-costs","display_name":"hospital costs","score":0.43299999833106995}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8553503751754761},{"id":"https://openalex.org/C2776476923","wikidata":"https://www.wikidata.org/wiki/Q7725","display_name":"Evening","level":2,"score":0.8511349558830261},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.5218609571456909},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.5132393836975098},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.4175386428833008},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.3493105173110962},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3224560022354126},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.10534247756004333},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C1276947","wikidata":"https://www.wikidata.org/wiki/Q333","display_name":"Astronomy","level":1,"score":0.0},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1093/ofid/ofad500.1875","doi":"https://doi.org/10.1093/ofid/ofad500.1875","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ofid/ofad500.1875","pdf_url":"https://academic.oup.com/ofid/article-pdf/10/Supplement_2/ofad500.1875/53771764/ofad500.1875.pdf","source":{"id":"https://openalex.org/S2735126445","display_name":"Open Forum Infectious Diseases","issn_l":"2328-8957","issn":["2328-8957"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infectious Diseases","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10679247","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10679247","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10679247/pdf/ofad500.1875.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infect Dis","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1093/ofid/ofad500.1875","doi":"https://doi.org/10.1093/ofid/ofad500.1875","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ofid/ofad500.1875","pdf_url":"https://academic.oup.com/ofid/article-pdf/10/Supplement_2/ofad500.1875/53771764/ofad500.1875.pdf","source":{"id":"https://openalex.org/S2735126445","display_name":"Open Forum Infectious Diseases","issn_l":"2328-8957","issn":["2328-8957"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Open Forum Infectious Diseases","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4389029306.pdf","grobid_xml":"https://content.openalex.org/works/W4389029306.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3118909787","https://openalex.org/W4283640987","https://openalex.org/W3118254076","https://openalex.org/W3096015198","https://openalex.org/W3095058055","https://openalex.org/W1997754558","https://openalex.org/W4307429573","https://openalex.org/W2091589398","https://openalex.org/W2551399095","https://openalex.org/W4312952294"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Hospital":[2],"medicine":[3],"physicians":[4,34],"providing":[5],"coverage":[6,163,256],"during":[7,19],"evening":[8],"and":[9,52,60,139,147,173,198,210,238,262,271,275,287,292,298,313,338],"night":[10,219],"shifts":[11,151,164,175,186],"are":[12,35],"often":[13],"responsible":[14],"for":[15,218,344],"higher":[16,234],"patient":[17,73,204],"volumes":[18],"these":[20,129,330],"busy":[21],"shifts.":[22],"Data":[23],"on":[24,77,136],"decisions":[25],"to":[26,56,63,106,117,154,158,167,171],"start":[27],"or":[28],"broaden":[29],"antibiotic":[30,40,58,96,196,284,310],"therapy":[31],"by":[32,273,290,302,318],"covering":[33],"limited.":[36],"Methods":[37],"We":[38,127],"evaluated":[39],"administration":[41,71,104],"data":[42,130],"from":[43,115],"Duke":[44],"University":[45],"Health":[46],"System":[47],"between":[48,149],"July":[49],"1,":[50],"2021":[51],"March":[53],"31,":[54],"2023":[55],"identify":[57],"\u201cstarts\u201d":[59],"\u201cescalations\u201d":[61],"attributed":[62],"hospitalists.":[64],"Starts":[65],"were":[66,83,121,221,232,248],"defined":[67,84],"as":[68,85,124,131,187],"the":[69,78,100,107,110,142,179,188],"first":[70],"per":[72,316],"encounter":[74],"without":[75],"antibiotics":[76,120,301],"preceding":[79],"calendar":[80],"day.":[81],"Escalations":[82],"an":[86,125],"increase":[87],"in":[88,99,109,333,341],"cumulative":[89],"spectrum":[90,97],"score":[91,108],"(using":[92],"a":[93,132],"previously":[94],"validated":[95],"index)":[98],"48":[101,111],"hours":[102,112],"following":[103],"compared":[105,141],"prior.":[113],"Shifts":[114],"intravenous":[116],"only":[118],"oral":[119],"not":[122],"counted":[123],"escalation.":[126],"visualized":[128],"heat":[133],"map":[134],"based":[135],"weekday-hour":[137],"combinations":[138],"then":[140],"median":[143],"number":[144],"of":[145,277,281,283,294,300,307,309,329],"starts":[146,197,217,231,270,286,297,312],"escalations":[148,200,247,272,289,299,315,323],"daytime":[150,185],"(weekdays":[152,165],"7AM":[153,157],"5PM,":[155],"weekends":[156,169],"2PM),":[159],"evening,":[160],"\u201ccross":[161],"cover,\u201d":[162],"5PM":[166],"10PM,":[168],"2PM":[170],"10PM),":[172],"overnight":[174],"(remaining":[176],"times),":[177],"using":[178],"Mann-Whitney":[180],"U":[181],"nonparametric":[182],"test":[183],"with":[184],"comparator":[189],"group.":[190],"Results":[191],"The":[192],"analysis":[193],"included":[194],"7,045":[195],"4,879":[199],"across":[201,325],"78,845":[202],"unique":[203],"admissions.":[205],"Heat":[206,279],"maps":[207,280],"(Figure":[208],"1A":[209],"B)":[211],"revealed":[212],"specific":[213],"practice":[214],"patterns.":[215],"Median":[216],"shift":[220,226,246,253,304],"significantly":[222,233,249],"lower":[223,250],"than":[224,251],"day":[225,252,276,293],"starts,":[227],"but":[228],"cross":[229,255],"cover":[230],"(p":[235],"=":[236,264],"0.011":[237],"p":[239,263],"<":[240],"0.001,":[241],"respectively,":[242,266],"Figure":[243,267],"2A).":[244],"Night":[245],"while":[254],"showed":[257],"no":[258],"difference":[259],"(p<":[260],"0.001":[261],"0.51,":[265],"2B).":[268],"Antibiotic":[269,322],"hour":[274,291,317],"week":[278,295],"counts":[282,308],"(A)":[285,311],"(B)":[288,314],"Hourly":[296],"hospitalist":[303,319],"Box-and-whisker":[305],"plots":[306],"shift.":[320],"Conclusion":[321],"differed":[324],"work":[326],"shifts;":[327],"visualization":[328],"patterns":[331],"aids":[332],"antimicrobial":[334,346],"prescribing":[335],"pattern":[336],"recognition":[337],"may":[339],"assist":[340],"finding":[342],"opportunities":[343],"supportive":[345],"stewardship":[347],"strategies.":[348],"Disclosures":[349],"Rebekah":[350],"W.":[351],"Moehring,":[352],"MD,":[353],"MPH,":[354],"FIDSA,":[355],"FSHEA,":[356],"UpToDate,":[357],"Inc.:":[358],"Author":[359],"Royalties":[360]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2023-11-27T00:00:00"}