{"id":"https://openalex.org/W4389007952","doi":"https://doi.org/10.1096/fasebj.30.1_supplement.1150.16","title":"Association between Circulating and Placental Vitamin D Biomarkers in Healthy Pregnant Women on a Controlled Diet with Equivalent Vitamin D Intake during the Third Trimester","display_name":"Association between Circulating and Placental Vitamin D Biomarkers in Healthy Pregnant Women on a Controlled Diet with Equivalent Vitamin D Intake during the Third Trimester","publication_year":2016,"publication_date":"2016-04-01","ids":{"openalex":"https://openalex.org/W4389007952","doi":"https://doi.org/10.1096/fasebj.30.1_supplement.1150.16"},"language":"en","primary_location":{"id":"doi:10.1096/fasebj.30.1_supplement.1150.16","doi":"https://doi.org/10.1096/fasebj.30.1_supplement.1150.16","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.30.1_supplement.1150.16","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054297854","display_name":"Heyjun Park","orcid":"https://orcid.org/0000-0003-3724-9590","observed_orcids":["https://orcid.org/0000-0003-3724-9590"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Heyjun Park","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, NY","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110249951","display_name":"Patsy M. Brannon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patsy M Brannon","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, NY","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013199881","display_name":"Allyson A. West","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allyson A West","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, NY","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064901980","display_name":"Jian Yan","orcid":"https://orcid.org/0000-0001-8597-9841","observed_orcids":["https://orcid.org/0000-0001-8597-9841"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jian Yan","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, NY","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063512499","display_name":"Xinyin Jiang","orcid":"https://orcid.org/0000-0001-6090-371X","observed_orcids":["https://orcid.org/0000-0001-6090-371X"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xinyin Jiang","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, NY","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086808734","display_name":"Cydne A. Perry","orcid":"https://orcid.org/0000-0001-8874-1978","observed_orcids":["https://orcid.org/0000-0001-8874-1978"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cydne A Perry","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, NY","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040098215","display_name":"Olga Malysheva","orcid":"https://orcid.org/0000-0002-8626-5071","observed_orcids":["https://orcid.org/0000-0002-8626-5071"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olga V Malysheva","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, NY","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047124475","display_name":"Saurabh Mehta","orcid":"https://orcid.org/0000-0003-3788-0665","observed_orcids":["https://orcid.org/0000-0003-3788-0665"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Saurabh Mehta","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, NY","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077583806","display_name":"Marie A. Caudill","orcid":"https://orcid.org/0000-0002-7192-5743","observed_orcids":["https://orcid.org/0000-0002-7192-5743"]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marie A Caudill","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, NY","institution_ids":["https://openalex.org/I205783295"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I205783295"],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.38272704,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"30","issue":"S1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10277","display_name":"Vitamin D Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13004","display_name":"Vitamin K Research Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11629","display_name":"Birth, Development, and Health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/vitamin-d","display_name":"vitamin D","score":0.7559999823570251},{"id":"https://openalex.org/keywords/placenta","display_name":"placenta","score":0.9739999771118164},{"id":"https://openalex.org/keywords/25-hydroxyvitamin-d3","display_name":"25-hydroxyvitamin D3","score":0.8830000162124634},{"id":"https://openalex.org/keywords/24-25-dihydroxyvitamin-d3","display_name":"24,25-dihydroxyvitamin D3","score":0.9980000257492065},{"id":"https://openalex.org/keywords/1-25-dihydroxyvitamin-d","display_name":"1,25-dihydroxyvitamin D","score":0.9409999847412109},{"id":"https://openalex.org/keywords/maternal-vitamin-d-status","display_name":"maternal vitamin D status","score":0.7680000066757202},{"id":"https://openalex.org/keywords/placental-gene-expression","display_name":"placental gene expression","score":0.8209999799728394},{"id":"https://openalex.org/keywords/cyp2r1","display_name":"CYP2R1","score":0.9559999704360962},{"id":"https://openalex.org/keywords/cyp27b1","display_name":"CYP27B1","score":0.9919999837875366},{"id":"https://openalex.org/keywords/cyp24a1","display_name":"CYP24A1","score":1.0},{"id":"https://openalex.org/keywords/vitamin-d-hydroxylases","display_name":"vitamin D hydroxylases","score":0.6539999842643738},{"id":"https://openalex.org/keywords/third-trimester","display_name":"third trimester","score":0.7509999871253967},{"id":"https://openalex.org/keywords/controlled-diet","display_name":"controlled diet","score":0.6990000009536743},{"id":"https://openalex.org/keywords/calcium-intake","display_name":"calcium intake","score":0.6190000176429749},{"id":"https://openalex.org/keywords/placental-transfer","display_name":"placental transfer","score":0.3790000081062317}],"concepts":[{"id":"https://openalex.org/C124490489","wikidata":"https://www.wikidata.org/wiki/Q7936963","display_name":"Vitamin D and neurology","level":2,"score":0.8413032293319702},{"id":"https://openalex.org/C2776953305","wikidata":"https://www.wikidata.org/wiki/Q1212935","display_name":"Placenta","level":4,"score":0.7761186361312866},{"id":"https://openalex.org/C76743606","wikidata":"https://www.wikidata.org/wiki/Q21110757","display_name":"CYP24A1","level":4,"score":0.7594082355499268},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6016029119491577},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5943112373352051},{"id":"https://openalex.org/C2779740938","wikidata":"https://www.wikidata.org/wiki/Q4138762","display_name":"vitamin D deficiency","level":3,"score":0.5769135355949402},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5285847187042236},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.5200304985046387},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.49272873997688293},{"id":"https://openalex.org/C2776940978","wikidata":"https://www.wikidata.org/wiki/Q34956","display_name":"Vitamin","level":2,"score":0.4511069059371948},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.4402163624763489},{"id":"https://openalex.org/C179639408","wikidata":"https://www.wikidata.org/wiki/Q417057","display_name":"Calcitriol receptor","level":3,"score":0.38818758726119995},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26252710819244385},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1096/fasebj.30.1_supplement.1150.16","doi":"https://doi.org/10.1096/fasebj.30.1_supplement.1150.16","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.30.1_supplement.1150.16","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092},{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.6735000014305115}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3779388111","display_name":null,"funder_award_id":"1843\u20103882","funder_id":"https://openalex.org/F4320306353","funder_display_name":"Gerber Foundation"},{"id":"https://openalex.org/G9000046477","display_name":null,"funder_award_id":"R03 HD080824\u201001A1","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320306353","display_name":"Gerber Foundation","ror":"https://ror.org/03ggcx620"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2761214342","https://openalex.org/W4308831900","https://openalex.org/W6939637653","https://openalex.org/W2006795051","https://openalex.org/W3009132402","https://openalex.org/W4221109655","https://openalex.org/W3133558559","https://openalex.org/W1518533472","https://openalex.org/W2566085762","https://openalex.org/W2560304219"],"abstract_inverted_index":{"This":[0],"10\u2010wk":[1],"feeding":[2],"study":[3,441],"sought":[4],"to":[5,442],"advance":[6],"understanding":[7],"of":[8,11,47,117,348],"the":[9,12,106,433,439,468,472,478],"role":[10],"placenta":[13,124,170,449,469],"in":[14,169,177,304,342,447,477],"maternal":[15,64,178,201,222,253,271,305,349,378,455,479],"vitamin":[16,28,48,66,96,133,444,457,473],"D":[17,29,32,38,42,67,74,78,97,134,161,226,246,275,302,324,328,410,445,458,474],"status.":[18],"To":[19,432],"achieve":[20],"this":[21,437],"aim,":[22],"we":[23],"assessed":[24],"associations":[25,293],"between":[26,296,454],"placental":[27,45,132,141,194,243,357,384,402,461],"metabolites":[30,68,135,446,459],"[25\u2010hydroxyvitamin":[31],"3":[33,35,39,43,70,75,157,162,196,204,227,247,256,276,298,352],"(25[OH]D":[34],"),":[36,54,58],"24,25\u2010dihydroxyvitamin":[37],"(24,25[OH]":[40],"2":[41,73,80,160,225,245,274,301,323,327,360,370,396,409,417,425],")],":[44],"expression":[46,368,386,404],"D\u2010related":[49],"genes":[50],"[25\u2010hydroxylase":[51],"(":[52,56,60,87],"CYP2R1":[53,385],"1a\u2010hydroxylase":[55],"CYP27B1":[57,358],"24\u2010hydroxylase":[59],"CYP24A1":[61,367,403],")]":[62],"and":[63,93,100,109,120,131,140,158,176,219,270,299,320,325,366,383,401,460,463],"blood":[65,110,179,272],"[25(OH)D":[69],",":[71,76],"24,25(OH)":[72,159,224,244,273,326],"1,25\u2010dihydroxyvitamin":[77],"(1,25[OH]":[79],"D)]":[81],"among":[82],"healthy":[83],"third\u2010trimester":[84],"pregnant":[85],"women":[86],"n":[88],"=26).":[89],"Participants":[90],"consumed":[91],"equivalent":[92],"rigorously":[94],"controlled":[95],"(515":[98],"IU/d)":[99],"calcium":[101],"intakes":[102],"(1445":[103],"mg/d)":[104],"throughout":[105],"third":[107,118],"trimester,":[108],"samples":[111],"were":[112,126,136,249,294,330],"obtained":[113],"at":[114,128,185,191,211,217,234,240,262,268,283,289,312,318,333,381,412,422,430],"study\u2010baseline":[115],"(beginning":[116],"trimester)":[119],"study\u2010end":[121,382],"(term),":[122],"while":[123],"tissues":[125],"collected":[127],"delivery.":[129],"Blood":[130],"measured":[137],"by":[138,147],"LC\u2010MS/MS,":[139],"gene":[142],"transcript":[143],"abundance":[144],"was":[145],"quantified":[146],"qRT\u2010PCR":[148],"with":[149,200,221,252,355,391,407],"Taqman":[150],"probes.":[151],"In":[152,376],"Pearson":[153],"correlation":[154,168],"analyses,":[155],"25(OH)D":[156,195,203,255,297,351,380],"concentrations":[163,197,248,303,347],"showed":[164,387],"a":[165,392],"strong":[166,452],"positive":[167,292],"[":[171,180,206,229,257,278,307,335],"r":[172,181,187,207,213,230,236,258,264,279,285,308,314,336],"=0.83,":[173],"P":[174,183,189,209,215,232,238,266,287,338,364,374,399,420,428],"<0.001],":[175],"=0.89,":[182],"<0.001":[184,190,210,216,239,267,288],"baseline;":[186,212,235,263,284,313,423],"=0.84,":[188],"study\u2010end].":[192,241,290,431],"Remarkably,":[193],"correlated":[198,251,331,353,406],"positively":[199,250,354,405],"serum":[202,254,350,379],"levels":[205,228,277,329,411],"=0.63,":[208,231],"=0.85,":[214],"study\u2010end],":[218,319],"also":[220],"circulating":[223,321,456],"=0.001":[233],"=0.81,":[237],"Similarly,":[242],"=0.45,":[259],"P=":[260,281,310,316],"0.03":[261],"=0.68,":[265],"study\u2010end]":[269],"=0.52,":[280],"0.01":[282],"=0.67,":[286],"Moreover,":[291],"observed":[295],"1,25(OH)":[300,322,408],"circulation":[306],"=0.47,":[309],"0.02":[311],"=0.36,":[315],"0.068":[317],"only":[332],"baseline":[334,346],"=0.44,":[337],"=0.02].":[339],"Of":[340],"note,":[341],"multivariate\u2010adjusted":[343],"regression":[344],"models,":[345],"both":[356,413],"[R":[359,369,395,416],"=0.86":[361],";":[362],"\u03b2=0.007;":[363],"=0.04]":[365],"=":[371],"0.70;":[372],"\u03b2=0.012;":[373],"=0.01].":[375],"addition,":[377],"an":[388],"inverse":[389],"relationship":[390],"borderline":[393],"significance":[394],"=0.92;":[397],"\u03b2=\u22120.006;":[398],"=0.06],":[400],"study\u2010time":[414],"points":[415],"=0.70;":[418],"\u03b2=0.0022;":[419],"=0.01":[421],"R":[424],"=0.67;":[426],"\u03b2=0.0017;":[427],"=0.03":[429],"best":[434],"our":[435],"knowledge,":[436],"is":[438],"first":[440],"quantify":[443],"human":[448],"tissue.":[450],"The":[451],"correlations":[453],"metabolic":[462],"genomic":[464],"readouts":[465],"suggest":[466],"that":[467],"may":[470],"modulate":[471],"metabolite":[475],"profile":[476],"compartment.":[480],"Support":[481],"or":[482],"Funding":[483],"Information":[484],"GERBER":[485],"FOUNDATION":[486],"1843\u20103882,":[487],"NIH":[488],"R03":[489],"HD080824\u201001A1":[490]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2023-11-27T00:00:00"}