{"id":"https://openalex.org/W4388978000","doi":"https://doi.org/10.1155/2023/6928167","title":"Chemical Application of Topological Indices in Infertility Treatment Drugs and QSPR Analysis","display_name":"Chemical Application of Topological Indices in Infertility Treatment Drugs and QSPR Analysis","publication_year":2023,"publication_date":"2023-11-24","ids":{"openalex":"https://openalex.org/W4388978000","doi":"https://doi.org/10.1155/2023/6928167","pmid":"https://pubmed.ncbi.nlm.nih.gov/38045557","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10691894"},"language":"en","primary_location":{"id":"doi:10.1155/2023/6928167","doi":"https://doi.org/10.1155/2023/6928167","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2023/6928167","pdf_url":"https://downloads.hindawi.com/journals/ijac/2023/6928167.pdf","source":{"id":"https://openalex.org/S127888171","display_name":"International Journal of Analytical Chemistry","issn_l":"1687-8760","issn":["1687-8760","1687-8779"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Analytical Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://downloads.hindawi.com/journals/ijac/2023/6928167.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026767153","display_name":"Sobia Sultana","orcid":"https://orcid.org/0009-0004-8599-5509","observed_orcids":["https://orcid.org/0009-0004-8599-5509"]},"institutions":[{"id":"https://openalex.org/I240666556","display_name":"Imam Mohammad ibn Saud Islamic University","ror":"https://ror.org/05gxjyb39","country_code":"SA","type":"education","lineage":["https://openalex.org/I240666556"]}],"countries":["SA"],"is_corresponding":true,"raw_author_name":"Sobia Sultana","raw_affiliation_strings":["Department of Mathematics and Statistics, Faculty of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), P.O. Box 90950, Riyadh 11623, Saudi Arabia"],"raw_orcid":"https://orcid.org/0009-0004-8599-5509","affiliations":[{"raw_affiliation_string":"Department of Mathematics and Statistics, Faculty of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), P.O. Box 90950, Riyadh 11623, Saudi Arabia","institution_ids":["https://openalex.org/I240666556"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5026767153"],"corresponding_institution_ids":["https://openalex.org/I240666556"],"apc_list":{"value":1500,"currency":"USD","value_usd":1500},"apc_paid":{"value":1500,"currency":"USD","value_usd":1500},"fwci":3.9628,"has_fulltext":true,"cited_by_count":14,"citation_normalized_percentile":{"value":0.95466302,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"2023","issue":null,"first_page":"1","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11476","display_name":"Graph theory and applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2607","display_name":"Discrete Mathematics and Combinatorics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11476","display_name":"Graph theory and applications","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2607","display_name":"Discrete Mathematics and Combinatorics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/3002","display_name":"Drug Discovery"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12292","display_name":"Graph Theory and Algorithms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/topological-indices","display_name":"topological indices","score":0.9950000047683716},{"id":"https://openalex.org/keywords/quantitative-structure-property-relationship","display_name":"QSPR","score":0.8040000200271606},{"id":"https://openalex.org/keywords/tamoxifen","display_name":"tamoxifen","score":0.9610000252723694},{"id":"https://openalex.org/keywords/mesterolone","display_name":"mesterolone","score":0.9940000176429749},{"id":"https://openalex.org/keywords/anastrozole","display_name":"anastrozole","score":0.9980000257492065},{"id":"https://openalex.org/keywords/letrozole","display_name":"letrozole","score":1.0},{"id":"https://openalex.org/keywords/chemical-graph-theory","display_name":"chemical graph theory","score":0.8849999904632568},{"id":"https://openalex.org/keywords/molecular-descriptors","display_name":"molecular descriptors","score":0.5789999961853027}],"concepts":[{"id":"https://openalex.org/C164126121","wikidata":"https://www.wikidata.org/wiki/Q766383","display_name":"Quantitative structure\u2013activity relationship","level":2,"score":0.7524313926696777},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.4710274338722229},{"id":"https://openalex.org/C159867001","wikidata":"https://www.wikidata.org/wiki/Q904942","display_name":"Topological index","level":2,"score":0.44061923027038574},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.43112149834632874},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4248817265033722},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.395039826631546},{"id":"https://openalex.org/C184720557","wikidata":"https://www.wikidata.org/wiki/Q7825049","display_name":"Topology (electrical circuits)","level":2,"score":0.3702307343482971},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2918185591697693},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.2177530825138092},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.11030879616737366}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1155/2023/6928167","doi":"https://doi.org/10.1155/2023/6928167","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2023/6928167","pdf_url":"https://downloads.hindawi.com/journals/ijac/2023/6928167.pdf","source":{"id":"https://openalex.org/S127888171","display_name":"International Journal of Analytical Chemistry","issn_l":"1687-8760","issn":["1687-8760","1687-8779"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Analytical Chemistry","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10691894","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10691894","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10691894/pdf/IJAC2023-6928167.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Anal Chem","raw_type":"Text"},{"id":"pmid:38045557","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38045557","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of analytical chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:92312f1b14a04b749327b900420a2d9c","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/92312f1b14a04b749327b900420a2d9c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Analytical Chemistry, Vol 2023 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1155/2023/6928167","doi":"https://doi.org/10.1155/2023/6928167","is_oa":true,"landing_page_url":"https://doi.org/10.1155/2023/6928167","pdf_url":"https://downloads.hindawi.com/journals/ijac/2023/6928167.pdf","source":{"id":"https://openalex.org/S127888171","display_name":"International Journal of Analytical Chemistry","issn_l":"1687-8760","issn":["1687-8760","1687-8779"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310319869","host_organization_name":"Hindawi Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310319869","https://openalex.org/P4310320595"],"host_organization_lineage_names":["Hindawi Publishing Corporation","Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Analytical Chemistry","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.6240000128746033}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4388978000.pdf","grobid_xml":"https://content.openalex.org/works/W4388978000.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W1488864287","https://openalex.org/W1975632762","https://openalex.org/W2000076674","https://openalex.org/W2011611181","https://openalex.org/W2021229217","https://openalex.org/W2051930839","https://openalex.org/W2055750281","https://openalex.org/W2067103561","https://openalex.org/W2115325963","https://openalex.org/W2186105795","https://openalex.org/W3116148010","https://openalex.org/W3167139849","https://openalex.org/W4226116856","https://openalex.org/W4280636434","https://openalex.org/W4280652585","https://openalex.org/W4284710088","https://openalex.org/W4290098642","https://openalex.org/W4308340770","https://openalex.org/W4309151456","https://openalex.org/W4309224591","https://openalex.org/W4312183765","https://openalex.org/W4316362423","https://openalex.org/W4319043494","https://openalex.org/W4366989392","https://openalex.org/W4379281870"],"related_works":["https://openalex.org/W7118174378","https://openalex.org/W4313063218","https://openalex.org/W7218313890","https://openalex.org/W4280636434","https://openalex.org/W4214686358","https://openalex.org/W4388995867","https://openalex.org/W7218068676","https://openalex.org/W4386738755","https://openalex.org/W7167418287","https://openalex.org/W4407043183"],"abstract_inverted_index":{"The":[0],"main":[1],"challenges":[2],"faced":[3],"by":[4,44],"medical":[5],"researchers":[6],"while":[7],"producing":[8],"novel":[9],"drugs":[10,109],"are":[11,91],"time":[12],"commitment,":[13],"amplified":[14],"costs,":[15],"creating":[16],"a":[17,26,66,78,119],"safety":[18],"profile":[19],"for":[20,115],"the":[21,46,57,75,98,102,123],"medications,":[22],"reduced":[23],"solubility,":[24],"and":[25,42,55,88,110,132],"lack":[27],"of":[28,49,59,69,80],"experimental":[29],"data.":[30],"Chemical":[31],"graph":[32],"theory":[33],"makes":[34],"an":[35],"important":[36],"theoretical":[37],"contribution":[38],"to":[39,64,93],"drug":[40,53],"development":[41],"design":[43],"investigating":[45],"structural":[47],"properties":[48],"molecules.":[50],"To":[51],"improve":[52],"research":[54],"assess":[56],"effectiveness":[58],"treatments,":[60],"topological":[61,99,113,126],"indices":[62],"aim":[63],"provide":[65],"mathematical":[67],"representation":[68],"molecular":[70],"structures.":[71],"In":[72],"this":[73],"study,":[74],"author":[76],"examined":[77],"number":[79],"recently":[81],"used":[82,92],"drugs,":[83],"including":[84],"tamoxifen,":[85],"mesterolone,":[86],"anastrozole,":[87],"letrozole":[89],"which":[90],"treat":[94],"infertility.":[95],"We":[96,117],"compute":[97],"descriptors":[100,127],"with":[101,106],"limiting":[103],"behaviors":[104],"associated":[105],"these":[107],"pharmaceutical":[108],"offer":[111],"degree-based":[112,125],"parameters":[114],"them.":[116],"conducted":[118],"QSPR":[120],"investigation":[121],"on":[122],"prospective":[124],"using":[128],"quadratic,":[129],"cubic,":[130],"exponential,":[131],"logarithmic":[133],"regression":[134],"models.":[135]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2023-11-25T00:00:00"}