{"id":"https://openalex.org/W4388940914","doi":"https://doi.org/10.3389/fmolb.2023.1214532","title":"Role of the microtubules in the electrical activity of the primary cilium of renal epithelial cells","display_name":"Role of the microtubules in the electrical activity of the primary cilium of renal epithelial cells","publication_year":2023,"publication_date":"2023-11-22","ids":{"openalex":"https://openalex.org/W4388940914","doi":"https://doi.org/10.3389/fmolb.2023.1214532","pmid":"https://pubmed.ncbi.nlm.nih.gov/38074099","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10702962"},"language":"en","primary_location":{"id":"doi:10.3389/fmolb.2023.1214532","doi":"https://doi.org/10.3389/fmolb.2023.1214532","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmolb.2023.1214532","pdf_url":"https://www.frontiersin.org/articles/10.3389/fmolb.2023.1214532/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S2595797843","display_name":"Frontiers in Molecular Biosciences","issn_l":"2296-889X","issn":["2296-889X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-140","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Molecular Biosciences","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fmolb.2023.1214532/pdf?isPublishedV2=False","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008924732","display_name":"Noelia Scarinci","orcid":"https://orcid.org/0000-0001-8859-4437","observed_orcids":["https://orcid.org/0000-0001-8859-4437"]},"institutions":[{"id":"https://openalex.org/I151201029","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59","country_code":"AR","type":"government","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4387155568"]},{"id":"https://openalex.org/I3130237646","display_name":"National University of Santiago del Estero","ror":"https://ror.org/01v9p7c03","country_code":"AR","type":"education","lineage":["https://openalex.org/I3130237646"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Noelia Scarinci","raw_affiliation_strings":["Laboratorio de Canales I\u00f3nicos, Instituto Multidisciplinario de Salud, Tecnolog\u00eda y Desarrollo, IMSaTeD (UNSE-CONICET), Santiago del Estero, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Canales I\u00f3nicos, Instituto Multidisciplinario de Salud, Tecnolog\u00eda y Desarrollo, IMSaTeD (UNSE-CONICET), Santiago del Estero, Argentina","institution_ids":["https://openalex.org/I151201029","https://openalex.org/I3130237646"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031166884","display_name":"Brenda C. Guti\u00e9rrez","orcid":"https://orcid.org/0000-0003-0307-0592","observed_orcids":["https://orcid.org/0000-0003-0307-0592"]},"institutions":[{"id":"https://openalex.org/I151201029","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59","country_code":"AR","type":"government","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4387155568"]},{"id":"https://openalex.org/I3130237646","display_name":"National University of Santiago del Estero","ror":"https://ror.org/01v9p7c03","country_code":"AR","type":"education","lineage":["https://openalex.org/I3130237646"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Brenda C. Gutierrez","raw_affiliation_strings":["Laboratorio de Canales I\u00f3nicos, Instituto Multidisciplinario de Salud, Tecnolog\u00eda y Desarrollo, IMSaTeD (UNSE-CONICET), Santiago del Estero, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Canales I\u00f3nicos, Instituto Multidisciplinario de Salud, Tecnolog\u00eda y Desarrollo, IMSaTeD (UNSE-CONICET), Santiago del Estero, Argentina","institution_ids":["https://openalex.org/I151201029","https://openalex.org/I3130237646"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040946395","display_name":"Virginia Helena Albarrac\u00edn","orcid":"https://orcid.org/0000-0002-4316-0720","observed_orcids":["https://orcid.org/0000-0002-4316-0720"]},"institutions":[{"id":"https://openalex.org/I127019355","display_name":"National University of Tucum\u00e1n","ror":"https://ror.org/04chzd762","country_code":"AR","type":"education","lineage":["https://openalex.org/I127019355"]},{"id":"https://openalex.org/I151201029","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59","country_code":"AR","type":"government","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4387155568"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Virginia H. Albarrac\u00edn","raw_affiliation_strings":["Centro Integral de Microscop\u00eda Electr\u00f3nica (CIME-CONICET-UNT), Tucum\u00e1n, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro Integral de Microscop\u00eda Electr\u00f3nica (CIME-CONICET-UNT), Tucum\u00e1n, Argentina","institution_ids":["https://openalex.org/I127019355","https://openalex.org/I151201029"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049277864","display_name":"Mar\u00eda del Roc\u00edo Cantero","orcid":"https://orcid.org/0000-0002-9690-8413","observed_orcids":["https://orcid.org/0000-0002-9690-8413"]},"institutions":[{"id":"https://openalex.org/I151201029","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59","country_code":"AR","type":"government","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4387155568"]},{"id":"https://openalex.org/I3130237646","display_name":"National University of Santiago del Estero","ror":"https://ror.org/01v9p7c03","country_code":"AR","type":"education","lineage":["https://openalex.org/I3130237646"]}],"countries":["AR"],"is_corresponding":false,"raw_author_name":"Mar\u00eda del Roc\u00edo Cantero","raw_affiliation_strings":["Laboratorio de Canales I\u00f3nicos, Instituto Multidisciplinario de Salud, Tecnolog\u00eda y Desarrollo, IMSaTeD (UNSE-CONICET), Santiago del Estero, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Canales I\u00f3nicos, Instituto Multidisciplinario de Salud, Tecnolog\u00eda y Desarrollo, IMSaTeD (UNSE-CONICET), Santiago del Estero, Argentina","institution_ids":["https://openalex.org/I151201029","https://openalex.org/I3130237646"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5065381860","display_name":"Horacio F. Cantiello","orcid":"https://orcid.org/0000-0001-7973-0804","observed_orcids":["https://orcid.org/0000-0001-7973-0804"]},"institutions":[{"id":"https://openalex.org/I151201029","display_name":"Consejo Nacional de Investigaciones Cient\u00edficas y T\u00e9cnicas","ror":"https://ror.org/03cqe8w59","country_code":"AR","type":"government","lineage":["https://openalex.org/I151201029","https://openalex.org/I4210123736","https://openalex.org/I4387155568"]},{"id":"https://openalex.org/I3130237646","display_name":"National University of Santiago del Estero","ror":"https://ror.org/01v9p7c03","country_code":"AR","type":"education","lineage":["https://openalex.org/I3130237646"]}],"countries":["AR"],"is_corresponding":true,"raw_author_name":"Horacio F. Cantiello","raw_affiliation_strings":["Laboratorio de Canales I\u00f3nicos, Instituto Multidisciplinario de Salud, Tecnolog\u00eda y Desarrollo, IMSaTeD (UNSE-CONICET), Santiago del Estero, Argentina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio de Canales I\u00f3nicos, Instituto Multidisciplinario de Salud, Tecnolog\u00eda y Desarrollo, IMSaTeD (UNSE-CONICET), Santiago del Estero, Argentina","institution_ids":["https://openalex.org/I151201029","https://openalex.org/I3130237646"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5065381860"],"corresponding_institution_ids":["https://openalex.org/I151201029","https://openalex.org/I3130237646"],"apc_list":{"value":3295,"currency":"USD","value_usd":3295},"apc_paid":{"value":3295,"currency":"USD","value_usd":3295},"fwci":0.4974,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.63351943,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"10","issue":null,"first_page":"1214532","last_page":"1214532"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11412","display_name":"Genetic and Kidney Cyst Diseases","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11412","display_name":"Genetic and Kidney Cyst Diseases","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11480","display_name":"Connexins and lens biology","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primary-cilia","display_name":"primary cilia","score":0.9929999709129333},{"id":"https://openalex.org/keywords/microtubules","display_name":"microtubules","score":0.9900000095367432},{"id":"https://openalex.org/keywords/axoneme","display_name":"axoneme","score":0.7870000004768372},{"id":"https://openalex.org/keywords/electrical-oscillations","display_name":"electrical oscillations","score":0.8870000243186951},{"id":"https://openalex.org/keywords/renal-epithelial-cells","display_name":"renal epithelial cells","score":0.8669999837875366},{"id":"https://openalex.org/keywords/ciliopathy","display_name":"ciliopathies","score":0.7879999876022339},{"id":"https://openalex.org/keywords/polycystin-2","display_name":"polycystin-2","score":0.9959999918937683},{"id":"https://openalex.org/keywords/ciliary-signaling","display_name":"ciliary signaling","score":0.6489999890327454},{"id":"https://openalex.org/keywords/time-frequency-analysis","display_name":"time-frequency analysis","score":0.5230000019073486},{"id":"https://openalex.org/keywords/ciliary-length","display_name":"ciliary length","score":0.3330000042915344}],"concepts":[{"id":"https://openalex.org/C100094513","wikidata":"https://www.wikidata.org/wiki/Q180436","display_name":"Cilium","level":2,"score":0.9151856899261475},{"id":"https://openalex.org/C20418707","wikidata":"https://www.wikidata.org/wiki/Q189933","display_name":"Microtubule","level":2,"score":0.7852528095245361},{"id":"https://openalex.org/C24870808","wikidata":"https://www.wikidata.org/wiki/Q792605","display_name":"Axoneme","level":4,"score":0.7157221436500549},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6563365459442139},{"id":"https://openalex.org/C2909009945","wikidata":"https://www.wikidata.org/wiki/Q189933","display_name":"Microtubule polymerization","level":4,"score":0.613249659538269},{"id":"https://openalex.org/C2910722709","wikidata":"https://www.wikidata.org/wiki/Q180436","display_name":"Motile cilium","level":3,"score":0.6008492708206177},{"id":"https://openalex.org/C195267511","wikidata":"https://www.wikidata.org/wiki/Q5119969","display_name":"Ciliogenesis","level":3,"score":0.5754181742668152},{"id":"https://openalex.org/C2910395002","wikidata":"https://www.wikidata.org/wiki/Q203031","display_name":"Ciliopathies","level":4,"score":0.5521888136863708},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5310025215148926},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.4482460618019104},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.4420020580291748},{"id":"https://openalex.org/C84425145","wikidata":"https://www.wikidata.org/wiki/Q422492","display_name":"Tubulin","level":3,"score":0.2055530548095703},{"id":"https://openalex.org/C115811362","wikidata":"https://www.wikidata.org/wiki/Q189998","display_name":"Flagellum","level":3,"score":0.09155100584030151},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08164450526237488},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3389/fmolb.2023.1214532","doi":"https://doi.org/10.3389/fmolb.2023.1214532","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmolb.2023.1214532","pdf_url":"https://www.frontiersin.org/articles/10.3389/fmolb.2023.1214532/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S2595797843","display_name":"Frontiers in Molecular Biosciences","issn_l":"2296-889X","issn":["2296-889X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-140","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Molecular Biosciences","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10702962","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10702962","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10702962/pdf/fmolb-10-1214532.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Mol Biosci","raw_type":"Text"},{"id":"pmid:38074099","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38074099","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in molecular biosciences","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:22c5d47efdc044afb5c9e1a4574b73fc","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/22c5d47efdc044afb5c9e1a4574b73fc","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Molecular Biosciences, Vol 10 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fmolb.2023.1214532","doi":"https://doi.org/10.3389/fmolb.2023.1214532","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fmolb.2023.1214532","pdf_url":"https://www.frontiersin.org/articles/10.3389/fmolb.2023.1214532/pdf?isPublishedV2=False","source":{"id":"https://openalex.org/S2595797843","display_name":"Frontiers in Molecular Biosciences","issn_l":"2296-889X","issn":["2296-889X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-140","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Molecular Biosciences","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4388940914.pdf","grobid_xml":"https://content.openalex.org/works/W4388940914.grobid-xml"},"referenced_works_count":61,"referenced_works":["https://openalex.org/W14931162","https://openalex.org/W41955574","https://openalex.org/W1484264815","https://openalex.org/W1492235284","https://openalex.org/W1492523231","https://openalex.org/W1557413015","https://openalex.org/W1962669878","https://openalex.org/W1975643213","https://openalex.org/W1976989450","https://openalex.org/W1979485887","https://openalex.org/W1990616504","https://openalex.org/W1998796212","https://openalex.org/W2005146894","https://openalex.org/W2013485362","https://openalex.org/W2014264816","https://openalex.org/W2021002124","https://openalex.org/W2028229711","https://openalex.org/W2036572722","https://openalex.org/W2042065671","https://openalex.org/W2054271542","https://openalex.org/W2060734073","https://openalex.org/W2071930240","https://openalex.org/W2078819077","https://openalex.org/W2084752796","https://openalex.org/W2086236344","https://openalex.org/W2092591922","https://openalex.org/W2094025678","https://openalex.org/W2095869636","https://openalex.org/W2096572443","https://openalex.org/W2100465045","https://openalex.org/W2103377139","https://openalex.org/W2108798512","https://openalex.org/W2112591804","https://openalex.org/W2119016119","https://openalex.org/W2122315648","https://openalex.org/W2129270900","https://openalex.org/W2157319245","https://openalex.org/W2160626345","https://openalex.org/W2163035368","https://openalex.org/W2167549607","https://openalex.org/W2167859555","https://openalex.org/W2171999245","https://openalex.org/W2319314169","https://openalex.org/W2418916350","https://openalex.org/W2478884216","https://openalex.org/W2556322097","https://openalex.org/W2598474916","https://openalex.org/W2887274298","https://openalex.org/W2970696603","https://openalex.org/W2999447209","https://openalex.org/W3004711670","https://openalex.org/W3044058343","https://openalex.org/W3164915348","https://openalex.org/W3204631862","https://openalex.org/W4237578579","https://openalex.org/W4246217303","https://openalex.org/W4250800175","https://openalex.org/W4300860633","https://openalex.org/W4303457383","https://openalex.org/W4381682987","https://openalex.org/W4388037473"],"related_works":["https://openalex.org/W6938977308","https://openalex.org/W1990616504","https://openalex.org/W2103504373","https://openalex.org/W2940168307","https://openalex.org/W2122315648","https://openalex.org/W7096458171","https://openalex.org/W2418916350","https://openalex.org/W2079100427","https://openalex.org/W3035924418","https://openalex.org/W2112591804"],"abstract_inverted_index":{"The":[0,170,231],"primary":[1,42,116,215,237],"cilium":[2,238],"is":[3],"a":[4,19,28,35,258],"non-motile":[5],"sensory":[6],"organelle":[7],"that":[8,173,190,235,249],"transduces":[9],"environmental":[10],"cues":[11],"into":[12],"cellular":[13],"responses.":[14],"It":[15],"comprises":[16],"an":[17,241,245],"axoneme,":[18],"core":[20],"of":[21,38,47,57,76,102,162,181,202,210,227],"nine":[22],"doublet":[23],"microtubules":[24],"(MTs)":[25],"coated":[26],"by":[27,32,68,207],"specialized":[29],"membrane":[30],"populated":[31],"receptors,":[33],"and":[34,78,97,110,113,133,147,155,167,175,224,255],"high":[36],"density":[37],"ion":[39],"channels.":[40],"Dysfunctional":[41],"cilia":[43,228],"generate":[44],"the":[45,54,69,73,153,156,159,199,222,236],"pathogenesis":[46],"several":[48],"diseases":[49],"known":[50],"as":[51,193,240],"ciliopathies.":[52,230],"However,":[53],"electrical":[55,74,89,119,163,182,200,225,242,251],"role":[56],"MTs":[58,80,177,204],"in":[59,100,108,158,229],"ciliary":[60,219],"signaling":[61,261],"remains":[62],"largely":[63],"unknown.":[64],"Herein,":[65],"we":[66],"determined":[67],"patch":[70],"clamp":[71],"technique":[72],"activity":[75],"cytoplasmic":[77,103,166,176],"axonemal":[79,168,174,203],"from":[81],"wild-type":[82],"LLC-PK1":[83],"renal":[84],"epithelial":[85],"cells.":[86],"We":[87,105,137],"observed":[88],"oscillations":[90,120,164,183,252],"with":[91,121,244],"fundamental":[92],"frequencies":[93,123],"at":[94,124,186],"\u223c39":[95],"Hz":[96,99,127,131,135],"\u223c93":[98,134],"sheets":[101],"MTs.":[104,169],"also":[106],"studied":[107],"situ":[109],"isolated,":[111],"intact":[112],"Triton":[114],"X-permeabilized":[115],"cilia,":[117,216],"observing":[118],"peak":[122],"either":[125],"29\u201349":[126],"(non-permeabilized)":[128],"or":[129],"\u223c40\u201349":[130],"(permeabilized)":[132],"(both).":[136],"applied":[138],"Empirical":[139],"Mode":[140],"Decomposition":[141],"(EMD),":[142],"Continuous":[143],"Wavelet":[144],"Transform":[145],"(CWT),":[146],"Cross-Correlation":[148],"Analysis":[149],"(CCA)":[150],"to":[151,221],"assess":[152],"differences":[154],"coherence":[157,185],"Time-Frequency":[160],"domains":[161],"between":[165,196],"data":[171],"indicate":[172],"show":[178],"different":[179],"patterns":[180],"preserving":[184],"specific":[187],"frequency":[188],"peaks":[189],"may":[191],"serve":[192],"electromagnetic":[194],"communication":[195],"compartments.":[197],"Further,":[198],"behavior":[201,226],"was":[205],"modified":[206],"siRNA":[208],"deletion":[209],"polycystin-2":[211],"(PC2),":[212],"which":[213],"lengthens":[214],"thus":[217],"linking":[218],"channels":[220],"morphological":[223],"encompassed":[232],"evidence":[233],"indicates":[234],"behaves":[239],"antenna,":[243],"excitable":[246],"MT":[247],"structure":[248],"produces":[250],"whose":[253],"synchronization":[254],"propagation":[256],"constitute":[257],"novel":[259],"cell":[260],"mechanism.":[262]},"counts_by_year":[{"year":2025,"cited_by_count":3}],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2023-11-24T00:00:00"}