{"id":"https://openalex.org/W4388917579","doi":"https://doi.org/10.1039/d3ob01617j","title":"Atropisomerism about aryl\u2013C(sp 3 ) bonds: chemically driven rotational pathway in cannabidiol derivatives","display_name":"Atropisomerism about aryl\u2013C(sp 3 ) bonds: chemically driven rotational pathway in cannabidiol derivatives","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4388917579","doi":"https://doi.org/10.1039/d3ob01617j","pmid":"https://pubmed.ncbi.nlm.nih.gov/38009203"},"language":"en","primary_location":{"id":"doi:10.1039/d3ob01617j","doi":"https://doi.org/10.1039/d3ob01617j","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d3ob01617j","pdf_url":null,"source":{"id":"https://openalex.org/S179810352","display_name":"Organic & Biomolecular Chemistry","issn_l":"1477-0520","issn":["1477-0520","1477-0539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic & Biomolecular Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068454585","display_name":"Cl\u00e9ment Denhez","orcid":"https://orcid.org/0000-0002-0386-9479","observed_orcids":["https://orcid.org/0000-0002-0386-9479"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210131305","display_name":"Institut de Chimie Mol\u00e9culaire de Reims","ror":"https://ror.org/03c0nx407","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210128300","https://openalex.org/I4210131305","https://openalex.org/I96226040"]},{"id":"https://openalex.org/I96226040","display_name":"Universit\u00e9 de Reims Champagne-Ardenne","ror":"https://ror.org/03hypw319","country_code":"FR","type":"education","lineage":["https://openalex.org/I96226040"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Cl\u00e9ment Denhez","raw_affiliation_strings":["Universit\u00e9 de Reims Champagne Ardenne, CNRS, ICMR UMR 7312, 51097 Reims, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Reims Champagne Ardenne, CNRS, ICMR UMR 7312, 51097 Reims, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210131305","https://openalex.org/I96226040"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049283780","display_name":"P\u00e9dro Lameiras","orcid":"https://orcid.org/0000-0001-8416-750X","observed_orcids":["https://orcid.org/0000-0001-8416-750X"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210131305","display_name":"Institut de Chimie Mol\u00e9culaire de Reims","ror":"https://ror.org/03c0nx407","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210128300","https://openalex.org/I4210131305","https://openalex.org/I96226040"]},{"id":"https://openalex.org/I96226040","display_name":"Universit\u00e9 de Reims Champagne-Ardenne","ror":"https://ror.org/03hypw319","country_code":"FR","type":"education","lineage":["https://openalex.org/I96226040"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Pedro Lameiras","raw_affiliation_strings":["Universit\u00e9 de Reims Champagne Ardenne, CNRS, ICMR UMR 7312, 51097 Reims, France"],"raw_orcid":"https://orcid.org/0000-0001-8416-750X","affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Reims Champagne Ardenne, CNRS, ICMR UMR 7312, 51097 Reims, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210131305","https://openalex.org/I96226040"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074426617","display_name":"Hatice Berber","orcid":"https://orcid.org/0000-0002-9160-7734","observed_orcids":["https://orcid.org/0000-0002-9160-7734"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210131305","display_name":"Institut de Chimie Mol\u00e9culaire de Reims","ror":"https://ror.org/03c0nx407","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210128300","https://openalex.org/I4210131305","https://openalex.org/I96226040"]},{"id":"https://openalex.org/I96226040","display_name":"Universit\u00e9 de Reims Champagne-Ardenne","ror":"https://ror.org/03hypw319","country_code":"FR","type":"education","lineage":["https://openalex.org/I96226040"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Hatice Berber","raw_affiliation_strings":["Universit\u00e9 de Reims Champagne Ardenne, CNRS, ICMR UMR 7312, 51097 Reims, France"],"raw_orcid":"https://orcid.org/0000-0002-9160-7734","affiliations":[{"raw_affiliation_string":"Universit\u00e9 de Reims Champagne Ardenne, CNRS, ICMR UMR 7312, 51097 Reims, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210131305","https://openalex.org/I96226040"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5074426617"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I4210131305","https://openalex.org/I96226040"],"apc_list":null,"apc_paid":null,"fwci":0.5839,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.50779958,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":97},"biblio":{"volume":"21","issue":"48","first_page":"9572","last_page":"9582"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13115","display_name":"Axial and Atropisomeric Chirality Synthesis","score":0.5791000127792358,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13115","display_name":"Axial and Atropisomeric Chirality Synthesis","score":0.5791000127792358,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12748","display_name":"Molecular spectroscopy and chirality","score":0.2484000027179718,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10414","display_name":"Cannabis and Cannabinoid Research","score":0.03620000183582306,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atropisomerism","display_name":"atropisomerism","score":0.9900000095367432},{"id":"https://openalex.org/keywords/cannabidiol-derivatives","display_name":"cannabidiol derivatives","score":0.9679999947547913},{"id":"https://openalex.org/keywords/rotational-barriers","display_name":"rotational barriers","score":0.5640000104904175},{"id":"https://openalex.org/keywords/transition-state","display_name":"transition state","score":0.777999997138977},{"id":"https://openalex.org/keywords/conformational-analysis","display_name":"conformational analysis","score":0.531000018119812}],"concepts":[{"id":"https://openalex.org/C167981757","wikidata":"https://www.wikidata.org/wiki/Q757764","display_name":"Atropisomer","level":2,"score":0.945514440536499},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9415651559829712},{"id":"https://openalex.org/C2776895053","wikidata":"https://www.wikidata.org/wiki/Q422917","display_name":"Cannabidiol","level":3,"score":0.8443295955657959},{"id":"https://openalex.org/C18705241","wikidata":"https://www.wikidata.org/wiki/Q1128023","display_name":"Conformational isomerism","level":3,"score":0.7574689984321594},{"id":"https://openalex.org/C2781076698","wikidata":"https://www.wikidata.org/wiki/Q718074","display_name":"Aryl","level":3,"score":0.7562367916107178},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.511728048324585},{"id":"https://openalex.org/C74050887","wikidata":"https://www.wikidata.org/wiki/Q848368","display_name":"Rotation (mathematics)","level":2,"score":0.4434545040130615},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.2865769863128662},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.15127447247505188},{"id":"https://openalex.org/C2777056318","wikidata":"https://www.wikidata.org/wiki/Q79817","display_name":"Cannabis","level":2,"score":0.06179681420326233},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.0},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1039/d3ob01617j","doi":"https://doi.org/10.1039/d3ob01617j","is_oa":false,"landing_page_url":"https://doi.org/10.1039/d3ob01617j","pdf_url":null,"source":{"id":"https://openalex.org/S179810352","display_name":"Organic & Biomolecular Chemistry","issn_l":"1477-0520","issn":["1477-0520","1477-0539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic & Biomolecular Chemistry","raw_type":"journal-article"},{"id":"pmid:38009203","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38009203","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Organic & biomolecular chemistry","raw_type":"Journal Article"},{"id":"pmh:oai:HAL:hal-04939774v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-04939774","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Organic & Biomolecular Chemistry, 2023, 21 (48), pp.9572-9582. ⟨10.1039/D3OB01617J⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322892","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":45,"referenced_works":["https://openalex.org/W1966949133","https://openalex.org/W1975755749","https://openalex.org/W2028834138","https://openalex.org/W2029667189","https://openalex.org/W2041351632","https://openalex.org/W2045609840","https://openalex.org/W2047505957","https://openalex.org/W2058616449","https://openalex.org/W2092157292","https://openalex.org/W2104919283","https://openalex.org/W2122839730","https://openalex.org/W2139916893","https://openalex.org/W2141154798","https://openalex.org/W2150697053","https://openalex.org/W2286340070","https://openalex.org/W2335442430","https://openalex.org/W2736178248","https://openalex.org/W2771301495","https://openalex.org/W2771897018","https://openalex.org/W2786849322","https://openalex.org/W2801098955","https://openalex.org/W2969307369","https://openalex.org/W2973622962","https://openalex.org/W2989893790","https://openalex.org/W2998095128","https://openalex.org/W3000308816","https://openalex.org/W3005191776","https://openalex.org/W3030203986","https://openalex.org/W3048898941","https://openalex.org/W3083406432","https://openalex.org/W3118578263","https://openalex.org/W3124203334","https://openalex.org/W3146452678","https://openalex.org/W3156169848","https://openalex.org/W3164693358","https://openalex.org/W4205759994","https://openalex.org/W4220733538","https://openalex.org/W4229439350","https://openalex.org/W4287980903","https://openalex.org/W4297093193","https://openalex.org/W4313480380","https://openalex.org/W4317862963","https://openalex.org/W4380550682","https://openalex.org/W4385443012","https://openalex.org/W4385480093"],"related_works":["https://openalex.org/W7036254125","https://openalex.org/W2286340070","https://openalex.org/W244803108","https://openalex.org/W7148391632","https://openalex.org/W2041351632","https://openalex.org/W1970652669","https://openalex.org/W2058541778","https://openalex.org/W2007983335","https://openalex.org/W2060818671","https://openalex.org/W2060521102"],"abstract_inverted_index":{"-substituent":[0],"led":[1],"to":[2,7,40],"similar":[3],"rotational":[4],"pathways":[5],"according":[6],"the":[8,26,33,36],"series:":[9],"through":[10],"TS1":[11],"in":[12,16],"arylcylohexenes":[13],"and":[14,32],"TS2":[15],"arylcyclohexanes.":[17],"Likewise,":[18],"conversion":[19],"of":[20,35],"arylcyclohexenes":[21],"into":[22],"both":[23],"series":[24],"affects":[25],"rotation":[27],"speed":[28],"by":[29],"decelerating":[30],"it,":[31],"nature":[34],"aryl":[37],"ring":[38],"seems":[39],"have":[41],"a":[42],"very":[43],"minor":[44],"effect":[45],"on":[46],"this":[47],"phenomenon.":[48]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":3}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2023-11-23T00:00:00"}