{"id":"https://openalex.org/W4388852376","doi":"https://doi.org/10.24875/rme.23000009","title":"Osteocalcina y su correlaci\u00f3n con grasa corporal, glucosa durante la CTOG y funci\u00f3n de la c\u00e9lula beta pancre\u00e1tica en pacientes con riesgo de diabetes","display_name":"Osteocalcina y su correlaci\u00f3n con grasa corporal, glucosa durante la CTOG y funci\u00f3n de la c\u00e9lula beta pancre\u00e1tica en pacientes con riesgo de diabetes","publication_year":2023,"publication_date":"2023-11-21","ids":{"openalex":"https://openalex.org/W4388852376","doi":"https://doi.org/10.24875/rme.23000009"},"language":"es","primary_location":{"id":"doi:10.24875/rme.23000009","doi":"https://doi.org/10.24875/rme.23000009","is_oa":true,"landing_page_url":"http://dx.doi.org/10.24875/rme.23000009","pdf_url":"http://www.revistadeendocrinologia.com/files/rme_23_10_4_170-177.pdf","source":{"id":"https://openalex.org/S4210205375","display_name":"Revista Mexicana de Endocrinolog\u00eda Metabolismo y Nutrici\u00f3n","issn_l":"2339-9643","issn":["2339-9643","2462-4144"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","latindex"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Mexicana de Endocrinolog\u00eda, Metabolismo y Nutrici\u00f3n","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"http://www.revistadeendocrinologia.com/files/rme_23_10_4_170-177.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Alberto Aguilar-Garc\u00eda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129858807","display_name":"Universidad de Guanajuato","ror":"https://ror.org/058cjye32","country_code":"MX","type":"education","lineage":["https://openalex.org/I129858807"]},{"id":"https://openalex.org/I4210143042","display_name":"Hospital Regional de Alta Especialidad del Baj\u00edo","ror":"https://ror.org/03hre7f61","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210143042"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Alberto Aguilar-Garc\u00eda","raw_affiliation_strings":["Departamento de Endocrinolog\u00eda , Hospital Regional de Alta Especialidad del Baj\u00edo ;","Departamento de Medicina y Nutrici\u00f3n, Laboratorio de Investigaci\u00f3n en Metabolismo, Universidad de Guanajuato, Campus Le\u00f3n;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Endocrinolog\u00eda , Hospital Regional de Alta Especialidad del Baj\u00edo ;","institution_ids":["https://openalex.org/I4210143042"]},{"raw_affiliation_string":"Departamento de Medicina y Nutrici\u00f3n, Laboratorio de Investigaci\u00f3n en Metabolismo, Universidad de Guanajuato, Campus Le\u00f3n;","institution_ids":["https://openalex.org/I129858807"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069094103","display_name":"Anaid Herrer\u00edas-Garc\u00eda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129858807","display_name":"Universidad de Guanajuato","ror":"https://ror.org/058cjye32","country_code":"MX","type":"education","lineage":["https://openalex.org/I129858807"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Anaid Herrer\u00edas-Garc\u00eda","raw_affiliation_strings":["Departamento de Medicina y Nutrici\u00f3n, Laboratorio de Investigaci\u00f3n en Metabolismo, Universidad de Guanajuato, Campus Le\u00f3n;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Medicina y Nutrici\u00f3n, Laboratorio de Investigaci\u00f3n en Metabolismo, Universidad de Guanajuato, Campus Le\u00f3n;","institution_ids":["https://openalex.org/I129858807"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093306778","display_name":"Anette M. Villanueva-Esqueda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210143042","display_name":"Hospital Regional de Alta Especialidad del Baj\u00edo","ror":"https://ror.org/03hre7f61","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210143042"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Anette M. Villanueva-Esqueda","raw_affiliation_strings":["Departamento de Investigaci\u00f3n , Hospital Regional de Alta Especialidad del Baj\u00edo. Le\u00f3n , Gto. , M\u00e9xico","Departamento de Endocrinolog\u00eda, Hospital Regional de Alta Especialidad del Baj\u00edo;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Investigaci\u00f3n , Hospital Regional de Alta Especialidad del Baj\u00edo. Le\u00f3n , Gto. , M\u00e9xico","institution_ids":["https://openalex.org/I4210143042"]},{"raw_affiliation_string":"Departamento de Endocrinolog\u00eda, Hospital Regional de Alta Especialidad del Baj\u00edo;","institution_ids":["https://openalex.org/I4210143042"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Gabriela A. Luna-Pati\u00f1o","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129858807","display_name":"Universidad de Guanajuato","ror":"https://ror.org/058cjye32","country_code":"MX","type":"education","lineage":["https://openalex.org/I129858807"]},{"id":"https://openalex.org/I4210143042","display_name":"Hospital Regional de Alta Especialidad del Baj\u00edo","ror":"https://ror.org/03hre7f61","country_code":"MX","type":"healthcare","lineage":["https://openalex.org/I4210143042"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Gabriela A. Luna-Pati\u00f1o","raw_affiliation_strings":["Departamento de Medicina y Nutrici\u00f3n , Laboratorio de Investigaci\u00f3n en Metabolismo , Universidad de Guanajuato , Campus Le\u00f3n ;","Departamento de Investigaci\u00f3n, Hospital Regional de Alta Especialidad del Baj\u00edo. Le\u00f3n, Gto., M\u00e9xico","RESUMEN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Medicina y Nutrici\u00f3n , Laboratorio de Investigaci\u00f3n en Metabolismo , Universidad de Guanajuato , Campus Le\u00f3n ;","institution_ids":["https://openalex.org/I129858807"]},{"raw_affiliation_string":"Departamento de Investigaci\u00f3n, Hospital Regional de Alta Especialidad del Baj\u00edo. Le\u00f3n, Gto., M\u00e9xico","institution_ids":["https://openalex.org/I4210143042"]},{"raw_affiliation_string":"RESUMEN","institution_ids":[]}]},{"author_position":"last","author":{"id":null,"display_name":"Rodolfo Guardado-Mendoza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I129858807","display_name":"Universidad de Guanajuato","ror":"https://ror.org/058cjye32","country_code":"MX","type":"education","lineage":["https://openalex.org/I129858807"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Rodolfo Guardado-Mendoza","raw_affiliation_strings":["Departamento de Medicina y Nutrici\u00f3n, Laboratorio de Investigaci\u00f3n en Metabolismo, Universidad de Guanajuato, Campus Le\u00f3n;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departamento de Medicina y Nutrici\u00f3n, Laboratorio de Investigaci\u00f3n en Metabolismo, Universidad de Guanajuato, Campus Le\u00f3n;","institution_ids":["https://openalex.org/I129858807"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"10","issue":"4","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.5932999849319458,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10027","display_name":"Diabetes, Cardiovascular Risks, and Lipoproteins","score":0.5932999849319458,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.18639999628067017,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.0471000000834465,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/osteocalcin","display_name":"osteocalcin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/type-2-diabetes-risk","display_name":"type 2 diabetes risk","score":0.9240000247955322},{"id":"https://openalex.org/keywords/beta-cell-function","display_name":"beta-cell function","score":0.7319999933242798},{"id":"https://openalex.org/keywords/visceral-fat","display_name":"visceral fat","score":0.593999981880188},{"id":"https://openalex.org/keywords/body-fat","display_name":"fat mass","score":0.7319999933242798},{"id":"https://openalex.org/keywords/oral-glucose-tolerance-test","display_name":"oral glucose tolerance test","score":0.7239999771118164},{"id":"https://openalex.org/keywords/plasma-glucose","display_name":"plasma glucose","score":0.7860000133514404},{"id":"https://openalex.org/keywords/insulin-sensitivity","display_name":"insulin sensitivity","score":0.8809999823570251},{"id":"https://openalex.org/keywords/insulin","display_name":"insulin","score":0.4869999885559082},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.6600000262260437},{"id":"https://openalex.org/keywords/hyperglycemia","display_name":"hyperglycemia","score":0.7639999985694885}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4682985842227936}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.24875/rme.23000009","doi":"https://doi.org/10.24875/rme.23000009","is_oa":true,"landing_page_url":"http://dx.doi.org/10.24875/rme.23000009","pdf_url":"http://www.revistadeendocrinologia.com/files/rme_23_10_4_170-177.pdf","source":{"id":"https://openalex.org/S4210205375","display_name":"Revista Mexicana de Endocrinolog\u00eda Metabolismo y Nutrici\u00f3n","issn_l":"2339-9643","issn":["2339-9643","2462-4144"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","latindex"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Mexicana de Endocrinolog\u00eda, Metabolismo y Nutrici\u00f3n","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:7b9449e9e9224e8d8a3b0ebd2db6759b","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/7b9449e9e9224e8d8a3b0ebd2db6759b","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Revista Mexicana de Endocrinolog\u00eda, Metabolismo y Nutrici\u00f3n, Vol 10, Iss 4 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.24875/rme.23000009","doi":"https://doi.org/10.24875/rme.23000009","is_oa":true,"landing_page_url":"http://dx.doi.org/10.24875/rme.23000009","pdf_url":"http://www.revistadeendocrinologia.com/files/rme_23_10_4_170-177.pdf","source":{"id":"https://openalex.org/S4210205375","display_name":"Revista Mexicana de Endocrinolog\u00eda Metabolismo y Nutrici\u00f3n","issn_l":"2339-9643","issn":["2339-9643","2462-4144"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","latindex"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Revista Mexicana de Endocrinolog\u00eda, Metabolismo y Nutrici\u00f3n","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4388852376.pdf","grobid_xml":"https://content.openalex.org/works/W4388852376.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W68686450","https://openalex.org/W1970239706","https://openalex.org/W2030795765","https://openalex.org/W2074092093","https://openalex.org/W2092854273","https://openalex.org/W2101371109","https://openalex.org/W2109728760","https://openalex.org/W2114528551","https://openalex.org/W2133795831","https://openalex.org/W2328756258","https://openalex.org/W2524981617","https://openalex.org/W2554775461","https://openalex.org/W2561543290","https://openalex.org/W2725077761","https://openalex.org/W2731692501","https://openalex.org/W2765612509","https://openalex.org/W2769137505","https://openalex.org/W2791767284","https://openalex.org/W2885595971","https://openalex.org/W3126489693","https://openalex.org/W3158831010","https://openalex.org/W3216923398","https://openalex.org/W4200148796","https://openalex.org/W4243871502","https://openalex.org/W4307847067"],"related_works":["https://openalex.org/W4283528140","https://openalex.org/W1916823812","https://openalex.org/W3087338047","https://openalex.org/W6907902783","https://openalex.org/W2003232657","https://openalex.org/W2739166867","https://openalex.org/W2137024891","https://openalex.org/W1591419669","https://openalex.org/W3022560344","https://openalex.org/W2020822441"],"abstract_inverted_index":{"Antecedentes:":[0],"La":[1],"hiperglucemia":[2],"se":[3,12,52,81],"desarrolla":[4],"progresivamente":[5],"desde":[6],"etapas":[7],"tempranas":[8],"y":[9,28,37,69,80,102,126,149,173,198,203,215],"m\u00faltiples":[10],"factores":[11],"relacionan":[13],"con":[14,44,95,107,118,127,146,162,179,192,200],"su":[15],"progresi\u00f3n.":[16],"Objetivo:":[17],"Evaluar":[18],"la":[19,59,67,72,91,152,163,166,183,193,196,213],"correlaci\u00f3n":[20,92,99,142,160],"entre":[21,93,105],"osteocalcina":[22],"(OC),":[23],"glucosa":[24,60,150,214],"plasm\u00e1tica,":[25],"grasa":[26,147],"visceral":[27],"funci\u00f3n":[29,70,164,181,194],"de":[30,47,55,63,71,85,98,100,121,129,133,144,156,165,182,188,195,212,217],"las":[31,103],"c\u00e9lulas":[32],"beta":[33],"(C\u03b2)":[34],"pancre\u00e1ticas.":[35],"Material":[36],"m\u00e9todos:":[38],"Estudio":[39],"transversal":[40],"comparativo":[41],"en":[42,87,177,209],"pacientes":[43,178],"alto":[45],"riesgo":[46,216],"diabetes":[48],"tipo":[49],"2":[50],"(DT2);":[51],"realiz\u00f3":[53],"curva":[54],"tolerancia":[56],"oral":[57],"a":[58,66],"(CTOG),":[61],"medici\u00f3n":[62],"insulina,":[64],"sensibilidad":[65],"insulina":[68],"C\u03b2.":[73,184],"Se":[74,89,110],"evalu\u00f3":[75],"composici\u00f3n":[76],"corporal":[77,148],"mediante":[78],"bioimpedancia":[79],"midieron":[82],"los":[83],"niveles":[84,155,187],"OC":[86,145,157,189],"suero.":[88],"analiz\u00f3":[90],"variables":[94],"el":[96,114,210],"coeficiente":[97],"Spearman":[101],"diferencias":[104],"grupos":[106],"ANOVA.":[108],"Resultados:":[109],"incluyeron":[111],"508":[112],"pacientes;":[113],"64.2%":[115],"fueron":[116,174],"mujeres,":[117],"edad":[119],"promedio":[120],"43":[122],"\u00b1":[123,137],"12":[124],"a\u00f1os":[125],"categor\u00eda":[128],"sobrepeso-":[130],"obesidad":[131],"(\u00edndice":[132],"masa":[134],"corporal:":[135],"29":[136],"6":[138],"kg/m2).":[139],"Hubo":[140],"una":[141,159],"negativa":[143],"durante":[151],"CTOG.":[153],"Los":[154,186],"tuvieron":[158],"positiva":[161],"C\u03b2":[167,197],"(r:":[168],"0.138,":[169],"p":[170],"=":[171],"0.003)":[172],"significativamente":[175],"menores":[176],"menor":[180],"Conclusiones:":[185],"correlacionaron":[190],"positivamente":[191],"negativamente":[199],"par\u00e1metros":[201],"antropom\u00e9tricos":[202],"bioqu\u00edmicos":[204],"que":[205],"denotan":[206],"un":[207],"deterioro":[208],"metabolismo":[211],"DT2.":[218]},"counts_by_year":[],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2023-11-22T00:00:00"}