{"id":"https://openalex.org/W4388780241","doi":"https://doi.org/10.1039/d3qm00809f","title":"Antisense DNA loaded 2D nanosheets for combined photodynamic and antisense cancer therapy","display_name":"Antisense DNA loaded 2D nanosheets for combined photodynamic and antisense cancer therapy","publication_year":2023,"publication_date":"2023-11-17","ids":{"openalex":"https://openalex.org/W4388780241","doi":"https://doi.org/10.1039/d3qm00809f"},"language":"en","primary_location":{"id":"doi:10.1039/d3qm00809f","doi":"https://doi.org/10.1039/d3qm00809f","is_oa":true,"landing_page_url":"https://doi.org/10.1039/d3qm00809f","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2024/qm/d3qm00809f","source":{"id":"https://openalex.org/S2765048856","display_name":"Materials Chemistry Frontiers","issn_l":"2052-1537","issn":["2052-1537"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Materials Chemistry Frontiers","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://pubs.rsc.org/en/content/articlepdf/2024/qm/d3qm00809f","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072336536","display_name":"Gowtham Raj","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I50557253","display_name":"Indian Institute of Science Education and Research Thiruvananthapuram","ror":"https://ror.org/01pe3t004","country_code":"IN","type":"education","lineage":["https://openalex.org/I50557253"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Gowtham Raj","raw_affiliation_strings":["School of Chemistry, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India","institution_ids":["https://openalex.org/I50557253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108962148","display_name":"D. S. Vasudev","orcid":"https://orcid.org/0009-0009-3339-4337","observed_orcids":["https://orcid.org/0009-0009-3339-4337"]},"institutions":[{"id":"https://openalex.org/I50557253","display_name":"Indian Institute of Science Education and Research Thiruvananthapuram","ror":"https://ror.org/01pe3t004","country_code":"IN","type":"education","lineage":["https://openalex.org/I50557253"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Vasudev D. S","raw_affiliation_strings":["School of Chemistry, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India","institution_ids":["https://openalex.org/I50557253"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Justin Prasad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I50557253","display_name":"Indian Institute of Science Education and Research Thiruvananthapuram","ror":"https://ror.org/01pe3t004","country_code":"IN","type":"education","lineage":["https://openalex.org/I50557253"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Justin Prasad","raw_affiliation_strings":["School of Chemistry, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India","institution_ids":["https://openalex.org/I50557253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093284390","display_name":"Erai Anbu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I50557253","display_name":"Indian Institute of Science Education and Research Thiruvananthapuram","ror":"https://ror.org/01pe3t004","country_code":"IN","type":"education","lineage":["https://openalex.org/I50557253"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Erai Anbu","raw_affiliation_strings":["School of Biology, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India","School of Chemistry, Indian Institute of Science Education and Research (IISER) Thiruvananthapuram, Trivandrum-695551, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biology, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India","institution_ids":["https://openalex.org/I50557253"]},{"raw_affiliation_string":"School of Chemistry, Indian Institute of Science Education and Research (IISER) Thiruvananthapuram, Trivandrum-695551, Kerala, India","institution_ids":["https://openalex.org/I50557253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019642567","display_name":"Soumakanya Ram","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I50557253","display_name":"Indian Institute of Science Education and Research Thiruvananthapuram","ror":"https://ror.org/01pe3t004","country_code":"IN","type":"education","lineage":["https://openalex.org/I50557253"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Soumakanya Ram","raw_affiliation_strings":["School of Chemistry, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India","institution_ids":["https://openalex.org/I50557253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109656573","display_name":"Geoffrey Bellson Daniel","orcid":"https://orcid.org/0009-0000-5607-789X","observed_orcids":["https://orcid.org/0009-0000-5607-789X"]},"institutions":[{"id":"https://openalex.org/I50557253","display_name":"Indian Institute of Science Education and Research Thiruvananthapuram","ror":"https://ror.org/01pe3t004","country_code":"IN","type":"education","lineage":["https://openalex.org/I50557253"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Geoffrey Bellson Daniel","raw_affiliation_strings":["School of Chemistry, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Chemistry, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India","institution_ids":["https://openalex.org/I50557253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026973794","display_name":"Nikhil Dev Narendradev","orcid":"https://orcid.org/0000-0002-5641-3571","observed_orcids":["https://orcid.org/0000-0002-5641-3571"]},"institutions":[{"id":"https://openalex.org/I50557253","display_name":"Indian Institute of Science Education and Research Thiruvananthapuram","ror":"https://ror.org/01pe3t004","country_code":"IN","type":"education","lineage":["https://openalex.org/I50557253"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Nikhil Dev Narendradev","raw_affiliation_strings":["School of Biology, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India"],"raw_orcid":"https://orcid.org/0000-0002-5641-3571","affiliations":[{"raw_affiliation_string":"School of Biology, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India","institution_ids":["https://openalex.org/I50557253"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079412406","display_name":"Srinivasa Murty Srinivasula","orcid":"https://orcid.org/0000-0003-4804-6916","observed_orcids":["https://orcid.org/0000-0003-4804-6916"]},"institutions":[{"id":"https://openalex.org/I50557253","display_name":"Indian Institute of Science Education and Research Thiruvananthapuram","ror":"https://ror.org/01pe3t004","country_code":"IN","type":"education","lineage":["https://openalex.org/I50557253"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Srinivasa Murty Srinivasula","raw_affiliation_strings":["School of Biology, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Biology, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India","institution_ids":["https://openalex.org/I50557253"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087373586","display_name":"Reji Varghese","orcid":"https://orcid.org/0000-0002-8513-9954","observed_orcids":["https://orcid.org/0000-0002-8513-9954","https://orcid.org/0000-0001-9729-3425"]},"institutions":[{"id":"https://openalex.org/I50557253","display_name":"Indian Institute of Science Education and Research Thiruvananthapuram","ror":"https://ror.org/01pe3t004","country_code":"IN","type":"education","lineage":["https://openalex.org/I50557253"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Reji Varghese","raw_affiliation_strings":["School of Chemistry, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India"],"raw_orcid":"https://orcid.org/0000-0002-8513-9954","affiliations":[{"raw_affiliation_string":"School of Chemistry, Indian Institute of Science Education and Research (IISER), Thiruvananthapuram, Trivandrum-695551, Kerala, India","institution_ids":["https://openalex.org/I50557253"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I50557253"],"apc_list":null,"apc_paid":null,"fwci":0.4727,"has_fulltext":true,"cited_by_count":6,"citation_normalized_percentile":{"value":0.52813002,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":97},"biblio":{"volume":"8","issue":"2","first_page":"553","last_page":"561"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.9057999849319458,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.9057999849319458,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.05299999937415123,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.031700000166893005,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/photodynamic-therapy","display_name":"photodynamic therapy","score":0.8050000071525574},{"id":"https://openalex.org/keywords/antisense-dna","display_name":"antisense DNA","score":0.972000002861023},{"id":"https://openalex.org/keywords/nanosheets","display_name":"nanosheets","score":0.9929999709129333},{"id":"https://openalex.org/keywords/combination-cancer-therapy","display_name":"combination cancer therapy","score":0.7519999742507935},{"id":"https://openalex.org/keywords/antisense-oligonucleotides","display_name":"antisense oligonucleotides","score":0.6259999871253967},{"id":"https://openalex.org/keywords/nanomedicine","display_name":"nanomedicine","score":0.43299999833106995}],"concepts":[{"id":"https://openalex.org/C2781323092","wikidata":"https://www.wikidata.org/wiki/Q1428072","display_name":"Photodynamic therapy","level":2,"score":0.8079131841659546},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.7027080059051514},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5375968813896179},{"id":"https://openalex.org/C2908938912","wikidata":"https://www.wikidata.org/wiki/Q4067124","display_name":"Antisense therapy","level":5,"score":0.4795374870300293},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.4686260521411896},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.45848745107650757},{"id":"https://openalex.org/C93275456","wikidata":"https://www.wikidata.org/wiki/Q756449","display_name":"Supramolecular chemistry","level":3,"score":0.4366590976715088},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.42910367250442505},{"id":"https://openalex.org/C2983331546","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer therapy","level":3,"score":0.4234811067581177},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4142061173915863},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.304755300283432},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21659865975379944},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1997794508934021},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.15254676342010498},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.09956285357475281},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0677240788936615},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.06770455837249756},{"id":"https://openalex.org/C129312508","wikidata":"https://www.wikidata.org/wiki/Q133686","display_name":"Oligonucleotide","level":3,"score":0.0663880705833435},{"id":"https://openalex.org/C14363569","wikidata":"https://www.wikidata.org/wiki/Q418639","display_name":"Locked nucleic acid","level":4,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1039/d3qm00809f","doi":"https://doi.org/10.1039/d3qm00809f","is_oa":true,"landing_page_url":"https://doi.org/10.1039/d3qm00809f","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2024/qm/d3qm00809f","source":{"id":"https://openalex.org/S2765048856","display_name":"Materials Chemistry Frontiers","issn_l":"2052-1537","issn":["2052-1537"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Materials Chemistry Frontiers","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1039/d3qm00809f","doi":"https://doi.org/10.1039/d3qm00809f","is_oa":true,"landing_page_url":"https://doi.org/10.1039/d3qm00809f","pdf_url":"https://pubs.rsc.org/en/content/articlepdf/2024/qm/d3qm00809f","source":{"id":"https://openalex.org/S2765048856","display_name":"Materials Chemistry Frontiers","issn_l":"2052-1537","issn":["2052-1537"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Materials Chemistry Frontiers","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.5683000087738037}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.7599999904632568}],"study_designs":[],"awards":[{"id":"https://openalex.org/G7126989584","display_name":null,"funder_award_id":"CRG/2022/002612","funder_id":"https://openalex.org/F4320334771","funder_display_name":"Science and Engineering Research Board"}],"funders":[{"id":"https://openalex.org/F4320334771","display_name":"Science and Engineering Research Board","ror":"https://ror.org/03ffdsr55"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4388780241.pdf","grobid_xml":"https://content.openalex.org/works/W4388780241.grobid-xml"},"referenced_works_count":44,"referenced_works":["https://openalex.org/W1763697926","https://openalex.org/W1974735351","https://openalex.org/W1998118539","https://openalex.org/W2034406436","https://openalex.org/W2093235084","https://openalex.org/W2332723607","https://openalex.org/W2515854919","https://openalex.org/W2592840643","https://openalex.org/W2724959339","https://openalex.org/W2767074976","https://openalex.org/W2786897058","https://openalex.org/W2902930512","https://openalex.org/W2981002433","https://openalex.org/W2982993342","https://openalex.org/W2996406026","https://openalex.org/W3030277853","https://openalex.org/W3037705037","https://openalex.org/W3042251874","https://openalex.org/W3043198063","https://openalex.org/W3134718230","https://openalex.org/W3135597654","https://openalex.org/W3138212497","https://openalex.org/W3147391455","https://openalex.org/W3162168433","https://openalex.org/W3162627671","https://openalex.org/W3173206646","https://openalex.org/W3174340986","https://openalex.org/W3184647138","https://openalex.org/W3195752403","https://openalex.org/W3204360553","https://openalex.org/W3204597064","https://openalex.org/W3207453959","https://openalex.org/W3217720585","https://openalex.org/W4214510983","https://openalex.org/W4229460033","https://openalex.org/W4280585707","https://openalex.org/W4282913507","https://openalex.org/W4290608695","https://openalex.org/W4295708926","https://openalex.org/W4296005336","https://openalex.org/W4306668460","https://openalex.org/W4312113542","https://openalex.org/W4320895128","https://openalex.org/W4366188506"],"related_works":["https://openalex.org/W2031617683","https://openalex.org/W2966695969","https://openalex.org/W4230036467","https://openalex.org/W4328022514","https://openalex.org/W4401100162","https://openalex.org/W4290608695","https://openalex.org/W4212940632","https://openalex.org/W2793199888","https://openalex.org/W2981938389","https://openalex.org/W4399051811"],"abstract_inverted_index":{"A":[0],"supramolecular":[1],"strategy":[2],"for":[3,21],"the":[4,22],"design":[5],"of":[6,12,25],"a":[7],"therapeutic":[8],"nanosystem":[9],"that":[10],"consists":[11],"PDT":[13,26],"active":[14],"2D":[15],"nanosheets":[16],"loaded":[17],"with":[18],"antisense":[19,28],"DNA":[20,29],"synergetic":[23],"combination":[24],"and":[27],"therapy":[30],"is":[31],"reported.":[32]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2023-11-18T00:00:00"}