{"id":"https://openalex.org/W4388575733","doi":"https://doi.org/10.1016/j.ccep.2023.10.006","title":"Pediatric and Familial Genetic Arrhythmia Syndromes\u2013Evaluation of Prolonged QTc\u2013Differential Diagnosis and what You Need to Know","display_name":"Pediatric and Familial Genetic Arrhythmia Syndromes\u2013Evaluation of Prolonged QTc\u2013Differential Diagnosis and what You Need to Know","publication_year":2023,"publication_date":"2023-11-10","ids":{"openalex":"https://openalex.org/W4388575733","doi":"https://doi.org/10.1016/j.ccep.2023.10.006","pmid":"https://pubmed.ncbi.nlm.nih.gov/38749641"},"language":"en","primary_location":{"id":"doi:10.1016/j.ccep.2023.10.006","doi":"https://doi.org/10.1016/j.ccep.2023.10.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ccep.2023.10.006","pdf_url":null,"source":{"id":"https://openalex.org/S2019908","display_name":"Cardiac Electrophysiology Clinics","issn_l":"1877-9182","issn":["1877-9182","1877-9190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiac Electrophysiology Clinics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005087112","display_name":"Mary C. Niu","orcid":"https://orcid.org/0000-0002-9289-6590","observed_orcids":["https://orcid.org/0000-0002-9289-6590"]},"institutions":[{"id":"https://openalex.org/I1324574813","display_name":"Primary Children's Hospital","ror":"https://ror.org/053hkmn05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I108785884","https://openalex.org/I1324574813"]},{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary C. Niu","raw_affiliation_strings":["Department of Pediatric Cardiology, University of Utah and Primary Children's Hospital, 100 Mario Capecchi Drive, Salt Lake City, UT 84113, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Cardiology, University of Utah and Primary Children's Hospital, 100 Mario Capecchi Drive, Salt Lake City, UT 84113, USA","institution_ids":["https://openalex.org/I1324574813","https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049588652","display_name":"Susan P. Etheridge","orcid":"https://orcid.org/0000-0002-2492-422X","observed_orcids":["https://orcid.org/0000-0002-2492-422X","https://orcid.org/0000-0002-0504-0242"]},"institutions":[{"id":"https://openalex.org/I1324574813","display_name":"Primary Children's Hospital","ror":"https://ror.org/053hkmn05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I108785884","https://openalex.org/I1324574813"]},{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Susan P. Etheridge","raw_affiliation_strings":["Department of Pediatric Cardiology, University of Utah and Primary Children's Hospital, 100 Mario Capecchi Drive, Salt Lake City, UT 84113, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Cardiology, University of Utah and Primary Children's Hospital, 100 Mario Capecchi Drive, Salt Lake City, UT 84113, USA","institution_ids":["https://openalex.org/I1324574813","https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057770335","display_name":"Martin Tristani\u2010Firouzi","orcid":"https://orcid.org/0000-0001-5916-442X","observed_orcids":["https://orcid.org/0000-0001-5916-442X"]},"institutions":[{"id":"https://openalex.org/I1324574813","display_name":"Primary Children's Hospital","ror":"https://ror.org/053hkmn05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I108785884","https://openalex.org/I1324574813"]},{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martin Tristani-Firouzi","raw_affiliation_strings":["Department of Pediatric Cardiology, University of Utah and Primary Children's Hospital, 100 Mario Capecchi Drive, Salt Lake City, UT 84113, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Cardiology, University of Utah and Primary Children's Hospital, 100 Mario Capecchi Drive, Salt Lake City, UT 84113, USA","institution_ids":["https://openalex.org/I1324574813","https://openalex.org/I223532165"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071575294","display_name":"Christina Y. Miyake","orcid":"https://orcid.org/0000-0002-3120-9320","observed_orcids":["https://orcid.org/0000-0002-3120-9320"]},"institutions":[{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]},{"id":"https://openalex.org/I4210147586","display_name":"Texas Children's Hospital","ror":"https://ror.org/05cz92x43","country_code":"US","type":"funder","lineage":["https://openalex.org/I4210147586"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Christina Y. Miyake","raw_affiliation_strings":["Department of Pediatrics, Division of Cardiology, Texas Children's Hospital and Baylor College of Medicine, 6651 Main Street, Houston, TX 77003, USA. Electronic address: cymiyake@bcm.edu","Department of Pediatrics, Division of Cardiology, Texas Children's Hospital and Baylor College of Medicine, 6651 Main Street, Houston, TX 77003, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Division of Cardiology, Texas Children's Hospital and Baylor College of Medicine, 6651 Main Street, Houston, TX 77003, USA. Electronic address: cymiyake@bcm.edu","institution_ids":["https://openalex.org/I181547552","https://openalex.org/I4210147586"]},{"raw_affiliation_string":"Department of Pediatrics, Division of Cardiology, Texas Children's Hospital and Baylor College of Medicine, 6651 Main Street, Houston, TX 77003, USA","institution_ids":["https://openalex.org/I181547552","https://openalex.org/I4210147586"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5071575294"],"corresponding_institution_ids":["https://openalex.org/I181547552","https://openalex.org/I4210147586"],"apc_list":{"value":2800,"currency":"USD","value_usd":2800},"apc_paid":null,"fwci":0.393,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.66524594,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"16","issue":"2","first_page":"195","last_page":"202"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10217","display_name":"Cardiac electrophysiology and arrhythmias","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11922","display_name":"Cardiovascular Effects of Exercise","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10598","display_name":"Cardiac pacing and defibrillation studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/qtc-prolongation","display_name":"QTc prolongation","score":0.7369999885559082},{"id":"https://openalex.org/keywords/pediatric-cardiac-arrhythmias","display_name":"pediatric arrhythmia","score":0.7319999933242798},{"id":"https://openalex.org/keywords/familial-arrhythmia","display_name":"familial arrhythmia","score":0.8489999771118164},{"id":"https://openalex.org/keywords/differential-diagnosis","display_name":"differential diagnosis","score":0.9860000014305115},{"id":"https://openalex.org/keywords/ecg-interpretation","display_name":"ECG interpretation","score":0.7459999918937683},{"id":"https://openalex.org/keywords/family-history-medicine","display_name":"family history (medicine)","score":0.8339999914169312},{"id":"https://openalex.org/keywords/genetic-testing","display_name":"genetic testing","score":0.550000011920929}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.909838080406189},{"id":"https://openalex.org/C2780801072","wikidata":"https://www.wikidata.org/wiki/Q837512","display_name":"Differential diagnosis","level":2,"score":0.7538113594055176},{"id":"https://openalex.org/C2779703243","wikidata":"https://www.wikidata.org/wiki/Q653924","display_name":"Long QT syndrome","level":3,"score":0.6403747797012329},{"id":"https://openalex.org/C2780673598","wikidata":"https://www.wikidata.org/wiki/Q285223","display_name":"Genetic testing","level":2,"score":0.6217959523200989},{"id":"https://openalex.org/C2779578097","wikidata":"https://www.wikidata.org/wiki/Q1484058","display_name":"Short QT syndrome","level":4,"score":0.5476998686790466},{"id":"https://openalex.org/C2781179581","wikidata":"https://www.wikidata.org/wiki/Q2857712","display_name":"Family history","level":2,"score":0.5199564695358276},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5002634525299072},{"id":"https://openalex.org/C206179267","wikidata":"https://www.wikidata.org/wiki/Q188952","display_name":"Medical history","level":2,"score":0.465317964553833},{"id":"https://openalex.org/C118441451","wikidata":"https://www.wikidata.org/wiki/Q12074763","display_name":"QT interval","level":2,"score":0.4228998124599457},{"id":"https://openalex.org/C2993153387","wikidata":"https://www.wikidata.org/wiki/Q285223","display_name":"Genetic diagnosis","level":3,"score":0.4205591678619385},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3256877064704895},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.2381671965122223},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2326371967792511},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.13829904794692993},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001145","descriptor_name":"Arrhythmias, Cardiac","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003937","descriptor_name":"Diagnosis, Differential","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005820","descriptor_name":"Genetic Testing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008133","descriptor_name":"Long QT Syndrome","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D008133","descriptor_name":"Long QT Syndrome","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008133","descriptor_name":"Long QT Syndrome","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ccep.2023.10.006","doi":"https://doi.org/10.1016/j.ccep.2023.10.006","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ccep.2023.10.006","pdf_url":null,"source":{"id":"https://openalex.org/S2019908","display_name":"Cardiac Electrophysiology Clinics","issn_l":"1877-9182","issn":["1877-9182","1877-9190"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiac Electrophysiology Clinics","raw_type":"journal-article"},{"id":"pmid:38749641","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38749641","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cardiac electrophysiology clinics","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4377517884","display_name":"The Discovery of Novel Genes in Inherited  Sudden Arrhythmic Death Syndromes","funder_award_id":"K23HL136932","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1977793893","https://openalex.org/W2027002532","https://openalex.org/W2060105258","https://openalex.org/W2092177398","https://openalex.org/W2152496222","https://openalex.org/W2160137065","https://openalex.org/W2291243145","https://openalex.org/W2561583382","https://openalex.org/W2972329507","https://openalex.org/W3135888199","https://openalex.org/W4280575968","https://openalex.org/W4310722512","https://openalex.org/W4312096931","https://openalex.org/W4385475927","https://openalex.org/W6846664662"],"related_works":["https://openalex.org/W2221229524","https://openalex.org/W1972968732","https://openalex.org/W2978213768","https://openalex.org/W2145203883","https://openalex.org/W4414879427","https://openalex.org/W2795128164","https://openalex.org/W2397809130","https://openalex.org/W4318930503","https://openalex.org/W2609149172","https://openalex.org/W3170707498"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-11-11T00:00:00"}