{"id":"https://openalex.org/W4388495140","doi":"https://doi.org/10.2174/0109298673278775231101064235","title":"Systematic Analysis of Tumor Stem Cell-related Gene Characteristics to Predict the PD-L1 Immunotherapy and Prognosis of Gastric Cancer","display_name":"Systematic Analysis of Tumor Stem Cell-related Gene Characteristics to Predict the PD-L1 Immunotherapy and Prognosis of Gastric Cancer","publication_year":2023,"publication_date":"2023-11-08","ids":{"openalex":"https://openalex.org/W4388495140","doi":"https://doi.org/10.2174/0109298673278775231101064235","pmid":"https://pubmed.ncbi.nlm.nih.gov/37936456"},"language":"en","primary_location":{"id":"doi:10.2174/0109298673278775231101064235","doi":"https://doi.org/10.2174/0109298673278775231101064235","is_oa":false,"landing_page_url":"https://doi.org/10.2174/0109298673278775231101064235","pdf_url":null,"source":{"id":"https://openalex.org/S33159018","display_name":"Current Medicinal Chemistry","issn_l":"0929-8673","issn":["0929-8673","1875-533X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Medicinal Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100363982","display_name":"Chenchen Wang","orcid":"https://orcid.org/0009-0004-2630-4149","observed_orcids":["https://orcid.org/0009-0004-2630-4149"]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chenchen Wang","raw_affiliation_strings":["Department of Gastrointestinal Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai,\n200000, China","Department of Oncology, Shanghai Medical College, Fudan University, Shanghai,\n200000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai,\n200000, China","institution_ids":["https://openalex.org/I4210093194"]},{"raw_affiliation_string":"Department of Oncology, Shanghai Medical College, Fudan University, Shanghai,\n200000, China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100383011","display_name":"Ying Chen","orcid":"https://orcid.org/0000-0001-7754-2367","observed_orcids":["https://orcid.org/0000-0001-7754-2367"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210107879","display_name":"Tongren Hospital","ror":"https://ror.org/01r8rcr36","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210107879"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ying Chen","raw_affiliation_strings":["Department of Oncology, Tongren Hospital, Shanghai Jiao Tong University School of\nMedicine, Shanghai, 200032, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Tongren Hospital, Shanghai Jiao Tong University School of\nMedicine, Shanghai, 200032, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210107879"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100624982","display_name":"Ru Zhou","orcid":"https://orcid.org/0000-0002-7220-9917","observed_orcids":["https://orcid.org/0000-0002-7220-9917"]},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I2801556517","display_name":"Ruijin Hospital","ror":"https://ror.org/01hv94n30","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2801556517"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ru Zhou","raw_affiliation_strings":["Department of General Surgery, Ruijin Hospital Luwan Branch,\nShanghai Jiaotong University School of Medicine, Shanghai, 200000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of General Surgery, Ruijin Hospital Luwan Branch,\nShanghai Jiaotong University School of Medicine, Shanghai, 200000, China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I2801556517"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100636314","display_name":"Yanan Yang","orcid":"https://orcid.org/0009-0000-2717-7453","observed_orcids":["https://orcid.org/0009-0000-2717-7453","https://orcid.org/0009-0008-6190-8094"]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ya\u2019nan Yang","raw_affiliation_strings":["Department of Gastrointestinal Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai,\n200000, China","Department of Oncology, Shanghai Medical College, Fudan University, Shanghai,\n200000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastrointestinal Medical Oncology, Fudan University Shanghai Cancer Center, Shanghai,\n200000, China","institution_ids":["https://openalex.org/I4210093194"]},{"raw_affiliation_string":"Department of Oncology, Shanghai Medical College, Fudan University, Shanghai,\n200000, China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5086369223","display_name":"Yantian Fang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I133868755","display_name":"Shanghai Medical College of Fudan University","ror":"https://ror.org/01zntxs11","country_code":"CN","type":"education","lineage":["https://openalex.org/I133868755","https://openalex.org/I24943067"]},{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210093194","display_name":"Fudan University Shanghai Cancer Center","ror":"https://ror.org/00my25942","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210093194"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yantian Fang","raw_affiliation_strings":["Department of Gastric\nSurgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China","Department of Oncology, Shanghai Medical College, Fudan University, Shanghai,\n200000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastric\nSurgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China","institution_ids":["https://openalex.org/I4210093194"]},{"raw_affiliation_string":"Department of Oncology, Shanghai Medical College, Fudan University, Shanghai,\n200000, China","institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5086369223"],"corresponding_institution_ids":["https://openalex.org/I133868755","https://openalex.org/I24943067","https://openalex.org/I4210093194"],"apc_list":null,"apc_paid":null,"fwci":0.2428,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.53295975,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":96},"biblio":{"volume":"31","issue":"17","first_page":"2467","last_page":"2482"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.7020999789237976,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.7020999789237976,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":0.12150000035762787,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.09260000288486481,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gastric-cancer","display_name":"gastric cancer","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cancer-stemness","display_name":"cancer stemness","score":0.9800000190734863},{"id":"https://openalex.org/keywords/immunotherapy-response-prediction","display_name":"immunotherapy response prediction","score":0.7049999833106995},{"id":"https://openalex.org/keywords/prognostic-gene-signature","display_name":"prognostic gene signature","score":0.9559999704360962},{"id":"https://openalex.org/keywords/immune-checkpoint-blockade","display_name":"immune checkpoint blockade","score":0.7929999828338623},{"id":"https://openalex.org/keywords/tumor-immune-dysfunction-and-exclusion","display_name":"tumor immune dysfunction and exclusion","score":0.8029999732971191},{"id":"https://openalex.org/keywords/immune-infiltration","display_name":"immune cell infiltration","score":0.7990000247955322},{"id":"https://openalex.org/keywords/risk-score","display_name":"risk score","score":0.6380000114440918},{"id":"https://openalex.org/keywords/nomogram","display_name":"nomogram","score":0.8130000233650208},{"id":"https://openalex.org/keywords/ercc6l","display_name":"ERCC6L","score":0.6679999828338623},{"id":"https://openalex.org/keywords/sumo3","display_name":"SUMO3","score":0.5600000023841858},{"id":"https://openalex.org/keywords/vps35","display_name":"VPS35","score":0.746999979019165}],"concepts":[{"id":"https://openalex.org/C2777701055","wikidata":"https://www.wikidata.org/wiki/Q1427096","display_name":"Immunotherapy","level":3,"score":0.7115814685821533},{"id":"https://openalex.org/C34626388","wikidata":"https://www.wikidata.org/wiki/Q721129","display_name":"Nomogram","level":2,"score":0.7104515433311462},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.6343048810958862},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.5737814903259277},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5037278532981873},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.47752419114112854},{"id":"https://openalex.org/C144301174","wikidata":"https://www.wikidata.org/wiki/Q7893852","display_name":"Univariate analysis","level":3,"score":0.44601088762283325},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4379047155380249},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4173014163970947},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.338445782661438},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32925713062286377},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.298598051071167},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.24053776264190674}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007167","descriptor_name":"Immunotherapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D014411","descriptor_name":"Neoplastic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014411","descriptor_name":"Neoplastic Stem Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D060890","descriptor_name":"B7-H1 Antigen","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":true},{"descriptor_ui":"D060890","descriptor_name":"B7-H1 Antigen","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D060890","descriptor_name":"B7-H1 Antigen","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.2174/0109298673278775231101064235","doi":"https://doi.org/10.2174/0109298673278775231101064235","is_oa":false,"landing_page_url":"https://doi.org/10.2174/0109298673278775231101064235","pdf_url":null,"source":{"id":"https://openalex.org/S33159018","display_name":"Current Medicinal Chemistry","issn_l":"0929-8673","issn":["0929-8673","1875-533X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Medicinal Chemistry","raw_type":"journal-article"},{"id":"pmid:37936456","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37936456","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current medicinal chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G602975305","display_name":null,"funder_award_id":"NO. 20214Y0395","funder_id":"https://openalex.org/F4320317789","funder_display_name":"Shanghai Municipal Health Commission"}],"funders":[{"id":"https://openalex.org/F4320317789","display_name":"Shanghai Municipal Health Commission","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W1140516890","https://openalex.org/W1966327575","https://openalex.org/W2035618305","https://openalex.org/W2146512944","https://openalex.org/W2299181842","https://openalex.org/W2559804019","https://openalex.org/W2698159436","https://openalex.org/W2793791988","https://openalex.org/W2886498337","https://openalex.org/W2895465883","https://openalex.org/W2896898180","https://openalex.org/W2900990058","https://openalex.org/W2943074432","https://openalex.org/W2946173685","https://openalex.org/W2949273159","https://openalex.org/W2950359183","https://openalex.org/W2985577249","https://openalex.org/W3002770500","https://openalex.org/W3049017521","https://openalex.org/W3084191442","https://openalex.org/W3111047872","https://openalex.org/W3119618910","https://openalex.org/W3128646645","https://openalex.org/W3151585181","https://openalex.org/W3161223865","https://openalex.org/W3195406213","https://openalex.org/W3197091336","https://openalex.org/W3205647492","https://openalex.org/W4200137052","https://openalex.org/W4225123279","https://openalex.org/W4237191081","https://openalex.org/W4281668878","https://openalex.org/W4285139933","https://openalex.org/W4285393826","https://openalex.org/W4293576787","https://openalex.org/W4294754570","https://openalex.org/W4319332990","https://openalex.org/W4386468044"],"related_works":["https://openalex.org/W4390538008","https://openalex.org/W3128081130","https://openalex.org/W3202208168","https://openalex.org/W3199775619","https://openalex.org/W4380080522","https://openalex.org/W4403001059","https://openalex.org/W4392795013","https://openalex.org/W4388373529","https://openalex.org/W3204645411","https://openalex.org/W3133792400"],"abstract_inverted_index":{"AIMS:":[0],"We":[1,33,50,69,93,242],"aimed":[2,51],"to":[3,11,26,41,52,60,163,231,238],"develop":[4,53,232],"a":[5,35,54,108,144,160,229,244],"prognostic":[6,36,55,111],"model":[7,37,56,112,138],"with":[8,38,57,100,143,199,251],"stemness-correlated":[9,39,58],"genes":[10,40,59,90,186],"evaluate":[12,42,61],"prognosis":[13,43,62,203,224,249],"and":[14,30,44,63,85,105,126,131,167,171,177,195,205,215,235,253],"immunotherapy":[15,45,64,262],"responsiveness":[16,46,65],"in":[17,47,66,202,210],"gastric":[18],"cancer":[19],"(GC).":[20],"BACKGROUND:":[21],"Tumor":[22],"stemness":[23,99,157],"is":[24],"related":[25,89],"intratumoral":[27],"heterogeneity,":[28],"immunosuppression,":[29],"anti-tumor":[31],"resistance.":[32],"developed":[34,114,243],"GC.":[48,67],"OBJECTIVE:":[49],"METHODS:":[68],"downloaded":[70],"single-cell":[71],"RNA":[72],"sequencing":[73],"(scRNA-seq)":[74],"data":[75],"of":[76,97,154,261],"GC":[77,87,148,264],"patients":[78,149,227],"from":[79],"the":[80,95,127,219],"Gene-Expression":[81],"Omnibus":[82],"(GEO)":[83],"database":[84],"screened":[86],"stemness-":[88],"using":[91,115],"CytoTRACE.":[92],"characterized":[94],"association":[96],"tumor":[98,164],"immune":[101,165,172,233],"checkpoint":[102],"blockade":[103],"(ICB)":[104],"immunity.":[106],"Thereafter,":[107],"9-stemness":[109],"signature-based":[110],"was":[113,141,197,208],"weighted":[116],"gene":[117,246],"co-expression":[118],"network":[119],"analysis":[120],"(WGCNA),":[121],"univariate":[122],"Cox":[123],"regression":[124,135],"analysis,":[125],"least":[128],"absolute":[129],"shrinkage":[130],"selection":[132],"operator":[133],"(LASSO)":[134],"analysis.":[136],"The":[137,156],"predictive":[139],"value":[140],"evaluated":[142],"nomogram.":[145],"RESULTS:":[146],"Early":[147],"had":[150],"significantly":[151],"higher":[152],"levels":[153],"stemness.":[155],"score":[158,170,217],"showed":[159],"negative":[161],"relationship":[162],"dysfunction":[166],"exclusion":[168],"(TIDE)":[169],"infiltration,":[173],"especially":[174],"T":[175],"cells":[176],"B":[178],"cells.":[179],"A":[180],"stemness-based":[181,245],"signature":[182,247,256],"based":[183],"on":[184],"9":[185],"(ERCC6L,":[187],"IQCC,":[188],"NKAPD1,":[189],"BLMH,":[190],"SLC25A15,":[191],"MRPL4,":[192],"VPS35,":[193],"SUMO3,":[194],"CINP)":[196],"constructed":[198],"good":[200],"performance":[201],"prediction,":[204],"its":[206],"robustness":[207],"validated":[209],"GSE26942":[211],"cohort.":[212],"Additionally,":[213],"nomogram":[214],"risk":[216],"exhibited":[218,228],"most":[220],"powerful":[221],"ability":[222],"for":[223,248,263],"prediction.":[225],"High-risk":[226],"tendency":[230],"escape":[234],"low":[236],"response":[237],"PD-L1":[239],"immunotherapy.":[240],"CONCLUSION:":[241],"prediction":[250],"accuracy":[252],"reliability.":[254],"This":[255],"also":[257],"helps":[258],"clinical":[259],"decision-making":[260],"patients.":[265]},"counts_by_year":[{"year":2025,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-11-09T00:00:00"}
