{"id":"https://openalex.org/W4388487103","doi":"https://doi.org/10.1371/journal.pbio.3002372","title":"The ortholog of human REEP1-4 is required for autophagosomal enclosure of ER-phagy/nucleophagy cargos in fission yeast","display_name":"The ortholog of human REEP1-4 is required for autophagosomal enclosure of ER-phagy/nucleophagy cargos in fission yeast","publication_year":2023,"publication_date":"2023-11-08","ids":{"openalex":"https://openalex.org/W4388487103","doi":"https://doi.org/10.1371/journal.pbio.3002372","pmid":"https://pubmed.ncbi.nlm.nih.gov/37939137","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10659188"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pbio.3002372","doi":"https://doi.org/10.1371/journal.pbio.3002372","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pbio.3002372","pdf_url":"https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002372&type=printable","source":{"id":"https://openalex.org/S154343897","display_name":"PLoS Biology","issn_l":"1544-9173","issn":["1544-9173","1545-7885"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002372&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019847788","display_name":"Chenxi Zou","orcid":"https://orcid.org/0009-0005-0481-3863","observed_orcids":["https://orcid.org/0009-0005-0481-3863"]},"institutions":[{"id":"https://openalex.org/I25254941","display_name":"Beijing Normal University","ror":"https://ror.org/022k4wk35","country_code":"CN","type":"education","lineage":["https://openalex.org/I25254941"]},{"id":"https://openalex.org/I4210086405","display_name":"National Institute of Biological Sciences, Beijing","ror":"https://ror.org/00wksha49","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210086405"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chen-Xi Zou","raw_affiliation_strings":["College of Life Sciences, Beijing Normal University, 100875, Beijing, China","National Institute of Biological Sciences, Beijing 102206, China","College of Life Sciences, Beijing Normal University, Beijing, China","National Institute of Biological Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"College of Life Sciences, Beijing Normal University, 100875, Beijing, China","institution_ids":["https://openalex.org/I25254941"]},{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing 102206, China","institution_ids":["https://openalex.org/I4210086405"]},{"raw_affiliation_string":"College of Life Sciences, Beijing Normal University, Beijing, China","institution_ids":["https://openalex.org/I25254941"]},{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210086405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044120508","display_name":"Zhu-Hui Ma","orcid":"https://orcid.org/0009-0007-2259-3061","observed_orcids":["https://orcid.org/0009-0007-2259-3061"]},"institutions":[{"id":"https://openalex.org/I4210086405","display_name":"National Institute of Biological Sciences, Beijing","ror":"https://ror.org/00wksha49","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210086405"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhu-Hui Ma","raw_affiliation_strings":["National Institute of Biological Sciences, Beijing 102206, China","National Institute of Biological Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing 102206, China","institution_ids":["https://openalex.org/I4210086405"]},{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210086405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084984192","display_name":"Zhaodi Jiang","orcid":"https://orcid.org/0000-0001-9480-6942","observed_orcids":["https://orcid.org/0000-0001-9480-6942"]},"institutions":[{"id":"https://openalex.org/I4210086405","display_name":"National Institute of Biological Sciences, Beijing","ror":"https://ror.org/00wksha49","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210086405"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhao-Di Jiang","raw_affiliation_strings":["National Institute of Biological Sciences, Beijing 102206, China","National Institute of Biological Sciences, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0001-9480-6942","affiliations":[{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing 102206, China","institution_ids":["https://openalex.org/I4210086405"]},{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210086405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008891889","display_name":"Zhao-Qian Pan","orcid":"https://orcid.org/0000-0003-0346-0259","observed_orcids":["https://orcid.org/0000-0003-0346-0259"]},"institutions":[{"id":"https://openalex.org/I4210086405","display_name":"National Institute of Biological Sciences, Beijing","ror":"https://ror.org/00wksha49","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210086405"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhao-Qian Pan","raw_affiliation_strings":["National Institute of Biological Sciences, Beijing 102206, China","National Institute of Biological Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing 102206, China","institution_ids":["https://openalex.org/I4210086405"]},{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210086405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031059398","display_name":"Dandan Xu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086405","display_name":"National Institute of Biological Sciences, Beijing","ror":"https://ror.org/00wksha49","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210086405"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dan-Dan Xu","raw_affiliation_strings":["National Institute of Biological Sciences, Beijing 102206, China","National Institute of Biological Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing 102206, China","institution_ids":["https://openalex.org/I4210086405"]},{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210086405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081269056","display_name":"Fang Suo","orcid":"https://orcid.org/0000-0001-6526-5489","observed_orcids":["https://orcid.org/0000-0001-6526-5489"]},"institutions":[{"id":"https://openalex.org/I4210086405","display_name":"National Institute of Biological Sciences, Beijing","ror":"https://ror.org/00wksha49","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210086405"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Fang Suo","raw_affiliation_strings":["National Institute of Biological Sciences, Beijing 102206, China","National Institute of Biological Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing 102206, China","institution_ids":["https://openalex.org/I4210086405"]},{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210086405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088700790","display_name":"Guang-Can Shao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210086405","display_name":"National Institute of Biological Sciences, Beijing","ror":"https://ror.org/00wksha49","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210086405"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guang-Can Shao","raw_affiliation_strings":["National Institute of Biological Sciences, Beijing 102206, China","National Institute of Biological Sciences, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing 102206, China","institution_ids":["https://openalex.org/I4210086405"]},{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210086405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062310761","display_name":"Meng\u2010Qiu Dong","orcid":"https://orcid.org/0000-0002-6094-1182","observed_orcids":["https://orcid.org/0000-0002-6094-1182"]},"institutions":[{"id":"https://openalex.org/I4210086405","display_name":"National Institute of Biological Sciences, Beijing","ror":"https://ror.org/00wksha49","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210086405"]},{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Meng-Qiu Dong","raw_affiliation_strings":["National Institute of Biological Sciences, Beijing 102206, China","Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing 102206, China","National Institute of Biological Sciences, Beijing, China","Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0002-6094-1182","affiliations":[{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing 102206, China","institution_ids":["https://openalex.org/I4210086405"]},{"raw_affiliation_string":"Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing 102206, China","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210086405"]},{"raw_affiliation_string":"Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China","institution_ids":["https://openalex.org/I99065089"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087923403","display_name":"Li\u2010Lin Du","orcid":"https://orcid.org/0000-0002-1028-7397","observed_orcids":["https://orcid.org/0000-0002-1028-7397"]},"institutions":[{"id":"https://openalex.org/I4210086405","display_name":"National Institute of Biological Sciences, Beijing","ror":"https://ror.org/00wksha49","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210086405"]},{"id":"https://openalex.org/I99065089","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549","country_code":"CN","type":"education","lineage":["https://openalex.org/I99065089"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Li-Lin Du","raw_affiliation_strings":["National Institute of Biological Sciences, Beijing 102206, China","Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing 102206, China","National Institute of Biological Sciences, Beijing, China","Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China"],"raw_orcid":"https://orcid.org/0000-0002-1028-7397","affiliations":[{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing 102206, China","institution_ids":["https://openalex.org/I4210086405"]},{"raw_affiliation_string":"Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing 102206, China","institution_ids":["https://openalex.org/I99065089"]},{"raw_affiliation_string":"National Institute of Biological Sciences, Beijing, China","institution_ids":["https://openalex.org/I4210086405"]},{"raw_affiliation_string":"Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing, China","institution_ids":["https://openalex.org/I99065089"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5087923403"],"corresponding_institution_ids":["https://openalex.org/I4210086405","https://openalex.org/I99065089"],"apc_list":{"value":5500,"currency":"USD","value_usd":5500},"apc_paid":{"value":5500,"currency":"USD","value_usd":5500},"fwci":1.9697,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.85379626,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"21","issue":"11","first_page":"e3002372","last_page":"e3002372"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/er-phagy","display_name":"ER-phagy","score":0.9259999990463257},{"id":"https://openalex.org/keywords/nucleophagy","display_name":"nucleophagy","score":0.9990000128746033},{"id":"https://openalex.org/keywords/selective-autophagy","display_name":"selective autophagy","score":0.8270000219345093},{"id":"https://openalex.org/keywords/schizosaccharomyces-pombe","display_name":"Schizosaccharomyces pombe","score":0.9229999780654907},{"id":"https://openalex.org/keywords/atg8","display_name":"ATG8","score":0.9620000123977661},{"id":"https://openalex.org/keywords/amphipathic-helix","display_name":"amphipathic helix","score":0.8759999871253967}],"concepts":[{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.7246533632278442},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.696612536907196},{"id":"https://openalex.org/C190062978","wikidata":"https://www.wikidata.org/wiki/Q79899","display_name":"Cytoplasm","level":2,"score":0.6406375765800476},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6240255236625671},{"id":"https://openalex.org/C2779429346","wikidata":"https://www.wikidata.org/wiki/Q2236682","display_name":"Schizosaccharomyces pombe","level":4,"score":0.6183661818504333},{"id":"https://openalex.org/C2776519988","wikidata":"https://www.wikidata.org/wiki/Q1317935","display_name":"Schizosaccharomyces","level":5,"score":0.5350205898284912},{"id":"https://openalex.org/C2780723820","wikidata":"https://www.wikidata.org/wiki/Q1934178","display_name":"Nucleus","level":2,"score":0.469632625579834},{"id":"https://openalex.org/C2780042272","wikidata":"https://www.wikidata.org/wiki/Q27548992","display_name":"ATG8","level":4,"score":0.4624927341938019},{"id":"https://openalex.org/C203522944","wikidata":"https://www.wikidata.org/wiki/Q288322","display_name":"Autophagy","level":3,"score":0.4204280972480774},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.33549776673316956},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.30964070558547974},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19509190320968628},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000071182","descriptor_name":"Autophagosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000071190","descriptor_name":"Autophagy-Related Protein 8 Family","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000071190","descriptor_name":"Autophagy-Related Protein 8 Family","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001343","descriptor_name":"Autophagy","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004721","descriptor_name":"Endoplasmic Reticulum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012568","descriptor_name":"Schizosaccharomyces","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D012568","descriptor_name":"Schizosaccharomyces","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D026901","descriptor_name":"Membrane Transport Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D059865","descriptor_name":"Endoplasmic Reticulum Stress","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1371/journal.pbio.3002372","doi":"https://doi.org/10.1371/journal.pbio.3002372","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pbio.3002372","pdf_url":"https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002372&type=printable","source":{"id":"https://openalex.org/S154343897","display_name":"PLoS Biology","issn_l":"1544-9173","issn":["1544-9173","1545-7885"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Biology","raw_type":"journal-article"},{"id":"doi:10.1101/2023.04.24.538066","doi":"https://doi.org/10.1101/2023.04.24.538066","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2023.04.24.538066","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2023/10/03/2023.04.24.538066.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:10659188","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10659188","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10659188/pdf/pbio.3002372.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS Biol","raw_type":"Text"},{"id":"pmid:37939137","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37939137","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS biology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:b96c4a34f02f423db6e3fac00e54fb51","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b96c4a34f02f423db6e3fac00e54fb51","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS Biology, Vol 21, Iss 11, p e3002372 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pbio.3002372","doi":"https://doi.org/10.1371/journal.pbio.3002372","is_oa":true,"landing_page_url":"https://doi.org/10.1371/journal.pbio.3002372","pdf_url":"https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3002372&type=printable","source":{"id":"https://openalex.org/S154343897","display_name":"PLoS Biology","issn_l":"1544-9173","issn":["1544-9173","1545-7885"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321540","display_name":"Ministry of Science and Technology of the People's Republic of China","ror":"https://ror.org/027s68j25"},{"id":"https://openalex.org/F4320322392","display_name":"Tsinghua University","ror":"https://ror.org/03cve4549"},{"id":"https://openalex.org/F4320332167","display_name":"Directorate for Biological Sciences","ror":"https://ror.org/001xhss06"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4388487103.pdf","grobid_xml":"https://content.openalex.org/works/W4388487103.grobid-xml"},"referenced_works_count":81,"referenced_works":["https://openalex.org/W1566724399","https://openalex.org/W1938173378","https://openalex.org/W1966535614","https://openalex.org/W1975075811","https://openalex.org/W1980730766","https://openalex.org/W1980942517","https://openalex.org/W1981503496","https://openalex.org/W1997168691","https://openalex.org/W2004361183","https://openalex.org/W2016518204","https://openalex.org/W2016772922","https://openalex.org/W2035730697","https://openalex.org/W2043039094","https://openalex.org/W2061235852","https://openalex.org/W2064474057","https://openalex.org/W2068625350","https://openalex.org/W2071632574","https://openalex.org/W2071767667","https://openalex.org/W2100605768","https://openalex.org/W2106114441","https://openalex.org/W2108744823","https://openalex.org/W2117112155","https://openalex.org/W2119309849","https://openalex.org/W2119993590","https://openalex.org/W2138795497","https://openalex.org/W2157843875","https://openalex.org/W2160973386","https://openalex.org/W2173041129","https://openalex.org/W2259709654","https://openalex.org/W2470601847","https://openalex.org/W2530057386","https://openalex.org/W2538297977","https://openalex.org/W2625879429","https://openalex.org/W2685662108","https://openalex.org/W2751583588","https://openalex.org/W2778591996","https://openalex.org/W2809059741","https://openalex.org/W2890512899","https://openalex.org/W2912641855","https://openalex.org/W2917864633","https://openalex.org/W2940118858","https://openalex.org/W2940394744","https://openalex.org/W2947808797","https://openalex.org/W2949863002","https://openalex.org/W2952055830","https://openalex.org/W2955889508","https://openalex.org/W2964898251","https://openalex.org/W2993376459","https://openalex.org/W2998839719","https://openalex.org/W2999304916","https://openalex.org/W2999620099","https://openalex.org/W2999850725","https://openalex.org/W3005235420","https://openalex.org/W3010852509","https://openalex.org/W3033615903","https://openalex.org/W3039255571","https://openalex.org/W3044674947","https://openalex.org/W3046130419","https://openalex.org/W3048164414","https://openalex.org/W3080457712","https://openalex.org/W3096491883","https://openalex.org/W3121357345","https://openalex.org/W3121652846","https://openalex.org/W3138647824","https://openalex.org/W3150790972","https://openalex.org/W3192382699","https://openalex.org/W3196694812","https://openalex.org/W3202105508","https://openalex.org/W3211293139","https://openalex.org/W3217060013","https://openalex.org/W4210589696","https://openalex.org/W4223510002","https://openalex.org/W4225644735","https://openalex.org/W4283593298","https://openalex.org/W4289132938","https://openalex.org/W4298127331","https://openalex.org/W4372332817","https://openalex.org/W4376641236","https://openalex.org/W4377982102","https://openalex.org/W4378070220","https://openalex.org/W4385664462"],"related_works":["https://openalex.org/W4390505144","https://openalex.org/W2992148597","https://openalex.org/W7125011243","https://openalex.org/W7147401697","https://openalex.org/W1566724399","https://openalex.org/W1977352903","https://openalex.org/W2043039094","https://openalex.org/W4385664462","https://openalex.org/W7214896298","https://openalex.org/W3046130419"],"abstract_inverted_index":{"Selective":[0],"macroautophagy":[1],"of":[2,45,62,67,107,136,176,190,202],"the":[3,8,31,43,60,64,74,87,101,104,113,133,187,198],"endoplasmic":[4],"reticulum":[5],"(ER)":[6],"and":[7,13,52,69,91,144,147,159,170,178,193,200],"nucleus,":[9],"known":[10,38],"as":[11,39],"ER-phagy":[12,51,68,134],"nucleophagy,":[14],"respectively,":[15],"are":[16],"processes":[17],"whose":[18],"mechanisms":[19],"remain":[20,110],"inadequately":[21],"understood.":[22],"Through":[23],"an":[24,183],"imaging-based":[25],"screen,":[26],"we":[27,154],"find":[28,131],"that":[29,132,156],"in":[30,100,168],"fission":[32,122],"yeast":[33,161],"Schizosaccharomyces":[34],"pombe,":[35],"Yep1":[36,137,167,177],"(also":[37],"Hva22":[40],"or":[41],"Rop1),":[42],"ortholog":[44,175],"human":[46,157],"REEP1-4,":[47],"is":[48,172],"essential":[49],"for":[50,56,166],"nucleophagy":[53,70],"but":[54],"not":[55,95],"bulk":[57],"autophagy.":[58],"In":[59],"absence":[61],"Yep1,":[63],"initial":[65],"phase":[66],"proceeds":[71],"normally,":[72],"with":[73,79,112],"ER-phagy/nucleophagy":[75,82,191],"receptor":[76],"Epr1":[77],"coassembling":[78],"Atg8.":[80],"However,":[81],"cargos":[83,192],"fail":[84],"to":[85,142],"reach":[86],"vacuole.":[88],"Instead,":[89],"nucleus-":[90],"cortical-ER-derived":[92],"membrane":[93,121],"structures":[94,109],"enclosed":[96],"within":[97],"autophagosomes":[98],"accumulate":[99],"cytoplasm.":[102],"Intriguingly,":[103],"outer":[105,120],"membranes":[106,146],"nucleus-derived":[108],"continuous":[111],"nuclear":[114],"envelope-ER":[115],"network,":[116],"suggesting":[117],"a":[118,173],"possible":[119],"defect":[123],"during":[124],"cargo":[125],"separation":[126],"from":[127],"source":[128],"compartments.":[129],"We":[130],"role":[135],"relies":[138],"on":[139,197],"its":[140,149],"abilities":[141],"self-interact":[143],"shape":[145],"requires":[148],"C-terminal":[150],"amphipathic":[151],"helices.":[152],"Moreover,":[153],"show":[155],"REEP1-4":[158],"budding":[160],"Atg40":[162,171],"can":[163],"functionally":[164],"substitute":[165],"ER-phagy,":[169],"divergent":[174],"REEP1-4.":[179],"Our":[180],"findings":[181],"uncover":[182],"unexpected":[184],"mechanism":[185],"governing":[186],"autophagosomal":[188],"enclosure":[189],"shed":[194],"new":[195],"light":[196],"functions":[199],"evolution":[201],"REEP":[203],"family":[204],"proteins.":[205]},"counts_by_year":[{"year":2026,"cited_by_count":8},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":7},{"year":2023,"cited_by_count":2}],"updated_date":"2026-11-09T13:22:03.289127","created_date":"2023-11-09T00:00:00"}