{"id":"https://openalex.org/W4388315931","doi":"https://doi.org/10.1093/oso/9780198577560.003.0031","title":"Introduction","display_name":"Introduction","publication_year":1992,"publication_date":"1992-09-17","ids":{"openalex":"https://openalex.org/W4388315931","doi":"https://doi.org/10.1093/oso/9780198577560.003.0031"},"language":"en","primary_location":{"id":"doi:10.1093/oso/9780198577560.003.0031","doi":"https://doi.org/10.1093/oso/9780198577560.003.0031","is_oa":false,"landing_page_url":"https://doi.org/10.1093/oso/9780198577560.003.0031","pdf_url":null,"source":{"id":"https://openalex.org/S4306463708","display_name":"Oxford University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Multiple Cholecystokinin Receptors in the CNS","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4388315652","display_name":"Multiple Cholecystokinin Receptors in the CNS"},"type":"book-chapter","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063501456","display_name":"Jacqueline N. Crawley","orcid":"https://orcid.org/0000-0002-1224-995X","observed_orcids":["https://orcid.org/0000-0002-1224-995X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Jacqueline N Crawley","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5063501456"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.44894652,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"327","last_page":"330"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.6050000190734863,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.6050000190734863,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.3747999966144562,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.008200000040233135,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cholecystokinin","display_name":"cholecystokinin","score":0.9490000009536743},{"id":"https://openalex.org/keywords/dopamine","display_name":"dopamine","score":0.972000002861023},{"id":"https://openalex.org/keywords/neuropeptide-coexistence","display_name":"neuropeptide coexistence","score":0.777999997138977},{"id":"https://openalex.org/keywords/midbrain-neurons","display_name":"midbrain neurons","score":0.8790000081062317},{"id":"https://openalex.org/keywords/ventral-tegmental-area","display_name":"ventral tegmental area","score":0.9049999713897705},{"id":"https://openalex.org/keywords/substantia-nigra","display_name":"substantia nigra","score":1.0},{"id":"https://openalex.org/keywords/mesocorticolimbic-pathway","display_name":"mesocorticolimbic pathway","score":0.9079999923706055},{"id":"https://openalex.org/keywords/nigrostriatal-pathway","display_name":"nigrostriatal pathway","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dopamine-receptor-antagonists","display_name":"dopamine antagonists","score":0.7450000047683716},{"id":"https://openalex.org/keywords/parkinson-s-disease","display_name":"Parkinson's disease","score":0.8769999742507935},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.8880000114440918}],"concepts":[{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.8098016381263733},{"id":"https://openalex.org/C2780938664","wikidata":"https://www.wikidata.org/wiki/Q753278","display_name":"Substantia nigra","level":4,"score":0.753994882106781},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.7354342341423035},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7193922996520996},{"id":"https://openalex.org/C2780948874","wikidata":"https://www.wikidata.org/wiki/Q640562","display_name":"Ventral tegmental area","level":4,"score":0.44842225313186646},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.39999449253082275}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1093/oso/9780198577560.003.0031","doi":"https://doi.org/10.1093/oso/9780198577560.003.0031","is_oa":false,"landing_page_url":"https://doi.org/10.1093/oso/9780198577560.003.0031","pdf_url":null,"source":{"id":"https://openalex.org/S4306463708","display_name":"Oxford University Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Multiple Cholecystokinin Receptors in the CNS","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2073414935","https://openalex.org/W4388315792","https://openalex.org/W1592010340","https://openalex.org/W4388296342","https://openalex.org/W1044851071","https://openalex.org/W2094258128","https://openalex.org/W907890703","https://openalex.org/W2032953447","https://openalex.org/W4388315821","https://openalex.org/W2424145167"],"abstract_inverted_index":{"Abstract":[0],"Current":[1],"information":[2],"on":[3],"the":[4,70,84,95,121,158],"coexistence":[5],"of":[6,13,28,72,120,150,157],"CCK":[7,111],"and":[8,38,42,46,60,106,112,124,139,160],"dopamine":[9,23,51,67,92,116],"in":[10,18,117,144,154,165,167],"mid-brain":[11,118],"neurons":[12,119],"several":[14],"species":[15],"is":[16,163],"presented":[17],"this":[19],"part.":[20],"The":[21,49,65,147],"mesocorticolimbic":[22,159],"system":[24],"mediates":[25,53],"a":[26],"variety":[27],"spontaneous":[29],"behaviour,":[30],"including":[31,56],"exploration,":[32],"feeding,":[33],"stress":[34],"responses,":[35],"drug":[36],"self-administration,":[37],"electrical":[39],"self-stimulation":[40],"(Stellar":[41],"Stellar":[43],"1985;":[44],"Kalivas":[45],"Nemeroff":[47],"1988).":[48],"nigrostriatal":[50,161],"pathway":[52],"motor":[54],"functions":[55],"coordinated":[57],"locomotor":[58],"activities":[59],"extrapyramidal":[61],"stereotypies":[62],"(DeLong":[63],"1990).":[64],"tubero-infundibular":[66],"tract":[68],"regulates":[69],"release":[71],"many":[73],"pituitary":[74],"hormones":[75],"(Meltzer":[76],"et":[77,128],"al.":[78,129],"1978).":[79],"Dopamine":[80],"receptor":[81],"antagonists":[82],"are":[83,94],"primary":[85,96],"treatment":[86,97],"for":[87,98,135],"schizophrenia":[88],"(Carlsson":[89],"1988),":[90],"while":[91],"precursors":[93],"Parkinson\u2019s":[99],"disease":[100],"(Caine":[101],"1977).The":[102],"discovery":[103],"by":[104],"Hokfelt":[105],"co-workers":[107],"that":[108],"two":[109],"neuropeptides,":[110],"neurotensin,":[113],"coexist":[114],"with":[115],"ventral":[122],"tegmentum":[123],"substantia":[125],"nigra":[126],"(Hokfelt":[127],"1986)":[130],"was":[131],"an":[132],"exciting":[133],"revelation":[134],"both":[136],"basic":[137],"researchers":[138],"clinicians":[140],"studying":[141],"dopaminergic":[142],"mechanisms":[143],"neuropsychiatric":[145],"syndromes.":[146],"anatomical":[148],"distribution":[149],"these":[151],"peptide":[152],"neuromodulators":[153],"discrete":[155],"subdivisions":[156],"pathways":[162],"described":[164],"detail":[166],"Chapter":[168],"32.":[169]},"counts_by_year":[],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2023-11-04T00:00:00"}