{"id":"https://openalex.org/W4388248554","doi":"https://doi.org/10.1016/j.jiph.2023.10.035","title":"Integrated bioinformatics approaches to investigate alterations in transcriptomic profiles of monkeypox infected human cell line model","display_name":"Integrated bioinformatics approaches to investigate alterations in transcriptomic profiles of monkeypox infected human cell line model","publication_year":2023,"publication_date":"2023-11-02","ids":{"openalex":"https://openalex.org/W4388248554","doi":"https://doi.org/10.1016/j.jiph.2023.10.035","pmid":"https://pubmed.ncbi.nlm.nih.gov/37992435"},"language":"en","primary_location":{"id":"doi:10.1016/j.jiph.2023.10.035","doi":"https://doi.org/10.1016/j.jiph.2023.10.035","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jiph.2023.10.035","pdf_url":null,"source":{"id":"https://openalex.org/S53706017","display_name":"Journal of Infection and Public Health","issn_l":"1876-0341","issn":["1876-0341","1876-035X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Infection and Public Health","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://doi.org/10.1016/j.jiph.2023.10.035","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070384492","display_name":"Gangga Anuraga","orcid":"https://orcid.org/0000-0002-0902-3968","observed_orcids":["https://orcid.org/0000-0002-0902-3968"]},"institutions":[{"id":"https://openalex.org/I4387930225","display_name":"Universitas PGRI Adi Buana Surabaya","ror":"https://ror.org/00g8jvh18","country_code":"ID","type":"education","lineage":["https://openalex.org/I4387930225"]},{"id":"https://openalex.org/I47519274","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94","country_code":"TW","type":"education","lineage":["https://openalex.org/I47519274"]},{"id":"https://openalex.org/I84653119","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784","country_code":"TW","type":"facility","lineage":["https://openalex.org/I84653119"]}],"countries":["ID","TW"],"is_corresponding":false,"raw_author_name":"Gangga Anuraga","raw_affiliation_strings":["PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan; Department of Statistics, Faculty of Science and Technology, Universitas PGRI Adi Buana, Surabaya, East Java 60234, Indonesia","Department of Statistics, Faculty of Science and Technology, Universitas PGRI Adi Buana, Surabaya, East Java 60234, Indonesia","PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan"],"raw_orcid":"https://orcid.org/0000-0002-0902-3968","affiliations":[{"raw_affiliation_string":"PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan; Department of Statistics, Faculty of Science and Technology, Universitas PGRI Adi Buana, Surabaya, East Java 60234, Indonesia","institution_ids":["https://openalex.org/I4387930225","https://openalex.org/I47519274","https://openalex.org/I84653119"]},{"raw_affiliation_string":"Department of Statistics, Faculty of Science and Technology, Universitas PGRI Adi Buana, Surabaya, East Java 60234, Indonesia","institution_ids":["https://openalex.org/I4387930225"]},{"raw_affiliation_string":"PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan","institution_ids":["https://openalex.org/I47519274","https://openalex.org/I84653119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090617101","display_name":"Jilu Lang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210096354","display_name":"The Seventh Affiliated Hospital of Sun Yat-sen University","ror":"https://ror.org/00rfd5b88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210096354"]},{"id":"https://openalex.org/I4210128628","display_name":"Peking University Shenzhen Hospital","ror":"https://ror.org/03kkjyb15","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210128628"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jilu Lang","raw_affiliation_strings":["Peking University Shenzhen Hospital Cardiovascular Surgery and Department of Cardiac Vascular Center, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, People's Republic of China","Department of Cardiac Vascular Center, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Peking University Shenzhen Hospital Cardiovascular Surgery and Department of Cardiac Vascular Center, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, People's Republic of China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210096354","https://openalex.org/I4210128628"]},{"raw_affiliation_string":"Department of Cardiac Vascular Center, The Seventh Affiliated Hospital, Sun Yat-Sen University, Shenzhen, People's Republic of China","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210096354"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024782599","display_name":"Do Thi Minh Xuan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47519274","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94","country_code":"TW","type":"education","lineage":["https://openalex.org/I47519274"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Do Thi Minh Xuan","raw_affiliation_strings":["Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan","institution_ids":["https://openalex.org/I47519274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060471872","display_name":"Hoang Dang Khoa Ta","orcid":"https://orcid.org/0000-0001-8809-239X","observed_orcids":["https://orcid.org/0000-0001-8809-239X"]},"institutions":[{"id":"https://openalex.org/I47519274","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94","country_code":"TW","type":"education","lineage":["https://openalex.org/I47519274"]},{"id":"https://openalex.org/I84653119","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784","country_code":"TW","type":"facility","lineage":["https://openalex.org/I84653119"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hoang Dang Khoa Ta","raw_affiliation_strings":["PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan","institution_ids":["https://openalex.org/I47519274","https://openalex.org/I84653119"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102621665","display_name":"Jiazhen Jiang","orcid":"https://orcid.org/0009-0005-1195-2036","observed_orcids":["https://orcid.org/0009-0005-1195-2036"]},"institutions":[{"id":"https://openalex.org/I24943067","display_name":"Fudan University","ror":"https://ror.org/013q1eq08","country_code":"CN","type":"education","lineage":["https://openalex.org/I24943067"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jia-Zhen Jiang","raw_affiliation_strings":["Emergency Department, Huashan Hospital North, Fudan University, Shanghai 201508, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emergency Department, Huashan Hospital North, Fudan University, Shanghai 201508, People's Republic of China","institution_ids":["https://openalex.org/I24943067","https://openalex.org/I4210159575"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100520720","display_name":"Zhengda Sun","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1343052199","display_name":"Kaiser Permanente","ror":"https://ror.org/00t60zh31","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1343052199"]},{"id":"https://openalex.org/I4405284138","display_name":"Kaiser Permanente Northern California","ror":"https://ror.org/0302f6d89","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343052199","https://openalex.org/I4405284138"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhengda Sun","raw_affiliation_strings":["Kaiser Permanente, Northern California Regional Laboratories, The Permanente Medical Group, 1725 Eastshore Hwy, Berkeley, CA 94710, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kaiser Permanente, Northern California Regional Laboratories, The Permanente Medical Group, 1725 Eastshore Hwy, Berkeley, CA 94710, USA","institution_ids":["https://openalex.org/I1343052199","https://openalex.org/I4405284138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048785235","display_name":"Sanskriti Dey","orcid":"https://orcid.org/0000-0001-8169-4996","observed_orcids":["https://orcid.org/0000-0001-8169-4996"]},"institutions":[{"id":"https://openalex.org/I47519274","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94","country_code":"TW","type":"education","lineage":["https://openalex.org/I47519274"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Sanskriti Dey","raw_affiliation_strings":["Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan","institution_ids":["https://openalex.org/I47519274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104330936","display_name":"Sachin Kumar","orcid":"https://orcid.org/0009-0009-5321-8197","observed_orcids":["https://orcid.org/0009-0009-5321-8197"]},"institutions":[{"id":"https://openalex.org/I4210133311","display_name":"Shoolini University","ror":"https://ror.org/02xe2fg84","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210133311"]},{"id":"https://openalex.org/I47519274","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94","country_code":"TW","type":"education","lineage":["https://openalex.org/I47519274"]}],"countries":["IN","TW"],"is_corresponding":false,"raw_author_name":"Sachin Kumar","raw_affiliation_strings":["Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan; Faculty of Biotechnology and Applied Sciences, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, India","Faculty of Biotechnology and Applied Sciences, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, India","Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan; Faculty of Biotechnology and Applied Sciences, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, India","institution_ids":["https://openalex.org/I4210133311","https://openalex.org/I47519274"]},{"raw_affiliation_string":"Faculty of Biotechnology and Applied Sciences, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, India","institution_ids":["https://openalex.org/I4210133311"]},{"raw_affiliation_string":"Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan","institution_ids":["https://openalex.org/I47519274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103003513","display_name":"Ayushi Singh","orcid":"https://orcid.org/0000-0002-9823-7078","observed_orcids":["https://orcid.org/0000-0002-9823-7078"]},"institutions":[{"id":"https://openalex.org/I4210133311","display_name":"Shoolini University","ror":"https://ror.org/02xe2fg84","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210133311"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ayushi Singh","raw_affiliation_strings":["Faculty of Biotechnology and Applied Sciences, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Biotechnology and Applied Sciences, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, India","institution_ids":["https://openalex.org/I4210133311"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Gagan Kajla","orcid":"https://orcid.org/0009-0009-2132-4534","observed_orcids":["https://orcid.org/0009-0009-2132-4534"]},"institutions":[{"id":"https://openalex.org/I4210133311","display_name":"Shoolini University","ror":"https://ror.org/02xe2fg84","country_code":"IN","type":"education","lineage":["https://openalex.org/I4210133311"]},{"id":"https://openalex.org/I47519274","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94","country_code":"TW","type":"education","lineage":["https://openalex.org/I47519274"]}],"countries":["IN","TW"],"is_corresponding":false,"raw_author_name":"Gagan Kajla","raw_affiliation_strings":["Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan; Faculty of Biotechnology and Applied Sciences, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, India","Faculty of Biotechnology and Applied Sciences, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, India","Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan"],"raw_orcid":"https://orcid.org/0009-0009-2132-4534","affiliations":[{"raw_affiliation_string":"Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan; Faculty of Biotechnology and Applied Sciences, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, India","institution_ids":["https://openalex.org/I4210133311","https://openalex.org/I47519274"]},{"raw_affiliation_string":"Faculty of Biotechnology and Applied Sciences, Shoolini University of Biotechnology and Management Sciences, Himachal Pradesh, India","institution_ids":["https://openalex.org/I4210133311"]},{"raw_affiliation_string":"Graduate Institute of Cancer Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University, Taipei 11031, Taiwan","institution_ids":["https://openalex.org/I47519274"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071723663","display_name":"Wei\u2010Jan Wang","orcid":"https://orcid.org/0000-0002-0811-8199","observed_orcids":["https://orcid.org/0000-0002-0811-8199"]},"institutions":[{"id":"https://openalex.org/I184693016","display_name":"China Medical University","ror":"https://ror.org/00v408z34","country_code":"TW","type":"education","lineage":["https://openalex.org/I184693016"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Wei-Jan Wang","raw_affiliation_strings":["Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan; Cancer Biology and Precision Therapeutics Center and Research Center for Cancer Biology, China Medical University, Taichung, Taiwan. Electronic address: cvcsky@cmu.edu.tw","Cancer Biology and Precision Therapeutics Center and Research Center for Cancer Biology, China Medical University, Taichung, Taiwan","Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan"],"raw_orcid":"https://orcid.org/0000-0002-0811-8199","affiliations":[{"raw_affiliation_string":"Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan; Cancer Biology and Precision Therapeutics Center and Research Center for Cancer Biology, China Medical University, Taichung, Taiwan. Electronic address: cvcsky@cmu.edu.tw","institution_ids":["https://openalex.org/I184693016"]},{"raw_affiliation_string":"Cancer Biology and Precision Therapeutics Center and Research Center for Cancer Biology, China Medical University, Taichung, Taiwan","institution_ids":["https://openalex.org/I184693016"]},{"raw_affiliation_string":"Department of Biological Science and Technology, College of Life Sciences, China Medical University, Taichung, Taiwan","institution_ids":["https://openalex.org/I184693016"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5042211118","display_name":"Chih\u2010Yang Wang","orcid":"https://orcid.org/0000-0002-4137-5074","observed_orcids":["https://orcid.org/0000-0002-4137-5074"]},"institutions":[{"id":"https://openalex.org/I4387930225","display_name":"Universitas PGRI Adi Buana Surabaya","ror":"https://ror.org/00g8jvh18","country_code":"ID","type":"education","lineage":["https://openalex.org/I4387930225"]},{"id":"https://openalex.org/I47519274","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94","country_code":"TW","type":"education","lineage":["https://openalex.org/I47519274"]},{"id":"https://openalex.org/I84653119","display_name":"Academia Sinica","ror":"https://ror.org/05bxb3784","country_code":"TW","type":"facility","lineage":["https://openalex.org/I84653119"]}],"countries":["ID","TW"],"is_corresponding":true,"raw_author_name":"Chih-Yang Wang","raw_affiliation_strings":["PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan; Department of Statistics, Faculty of Science and Technology, Universitas PGRI Adi Buana, Surabaya, East Java 60234, Indonesia; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei 11031, Taiwan. Electronic address: chihyang@tmu.edu.tw","Department of Statistics, Faculty of Science and Technology, Universitas PGRI Adi Buana, Surabaya, East Java 60234, Indonesia","PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan","TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei 11031, Taiwan"],"raw_orcid":"https://orcid.org/0000-0002-4137-5074","affiliations":[{"raw_affiliation_string":"PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan; Department of Statistics, Faculty of Science and Technology, Universitas PGRI Adi Buana, Surabaya, East Java 60234, Indonesia; TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei 11031, Taiwan. Electronic address: chihyang@tmu.edu.tw","institution_ids":["https://openalex.org/I4387930225","https://openalex.org/I47519274","https://openalex.org/I84653119"]},{"raw_affiliation_string":"Department of Statistics, Faculty of Science and Technology, Universitas PGRI Adi Buana, Surabaya, East Java 60234, Indonesia","institution_ids":["https://openalex.org/I4387930225"]},{"raw_affiliation_string":"PhD Program for Cancer Molecular Biology and Drug Discovery, College of Medical Science and Technology, Taipei Medical University and Academia Sinica, Taipei 11031, Taiwan","institution_ids":["https://openalex.org/I47519274","https://openalex.org/I84653119"]},{"raw_affiliation_string":"TMU Research Center of Cancer Translational Medicine, Taipei Medical University, Taipei 11031, Taiwan","institution_ids":["https://openalex.org/I47519274"]}]}],"institutions":[],"countries_distinct_count":5,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5042211118","https://openalex.org/A5071723663"],"corresponding_institution_ids":["https://openalex.org/I184693016","https://openalex.org/I4387930225","https://openalex.org/I47519274","https://openalex.org/I84653119"],"apc_list":{"value":2000,"currency":"USD","value_usd":2000},"apc_paid":{"value":2000,"currency":"USD","value_usd":2000},"fwci":3.0669,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.92607121,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"17","issue":"1","first_page":"60","last_page":"69"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11767","display_name":"Poxvirus research and outbreaks","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11767","display_name":"Poxvirus research and outbreaks","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mpox","display_name":"monkeypox","score":0.8820000290870667},{"id":"https://openalex.org/keywords/monkeypox-virus","display_name":"monkeypox virus","score":0.968999981880188},{"id":"https://openalex.org/keywords/orthopoxvirus","display_name":"orthopoxvirus","score":0.9440000057220459},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.6639999747276306},{"id":"https://openalex.org/keywords/hela-cells","display_name":"HeLa cells","score":0.8899999856948853},{"id":"https://openalex.org/keywords/viral-infection","display_name":"viral infection","score":0.4490000009536743},{"id":"https://openalex.org/keywords/immune-signaling-pathways","display_name":"immune signaling pathways","score":0.5960000157356262},{"id":"https://openalex.org/keywords/notch-signaling","display_name":"Notch signaling","score":0.6759999990463257},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.8050000071525574},{"id":"https://openalex.org/keywords/mapk-signaling","display_name":"MAPK signaling","score":0.9620000123977661},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.7289999723434448},{"id":"https://openalex.org/keywords/viral-replication","display_name":"viral replication","score":0.6779999732971191},{"id":"https://openalex.org/keywords/virus-host-interactions","display_name":"host-virus interaction","score":0.5920000076293945},{"id":"https://openalex.org/keywords/gene-co-regulation","display_name":"gene co-regulation","score":0.4560000002384186},{"id":"https://openalex.org/keywords/viral-pathogenesis","display_name":"viral pathogenesis","score":0.4519999921321869},{"id":"https://openalex.org/keywords/cytokines-and-chemokines","display_name":"cytokines and chemokines","score":0.5450000166893005},{"id":"https://openalex.org/keywords/metabolic-pathways","display_name":"metabolic pathways","score":0.4869999885559082}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7362013459205627},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.4610198736190796},{"id":"https://openalex.org/C152724338","wikidata":"https://www.wikidata.org/wiki/Q909442","display_name":"KEGG","level":5,"score":0.45391562581062317},{"id":"https://openalex.org/C54174078","wikidata":"https://www.wikidata.org/wiki/Q3197188","display_name":"Kinome","level":3,"score":0.4463222026824951},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.380590558052063},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.36140549182891846},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3083334267139435},{"id":"https://openalex.org/C162317418","wikidata":"https://www.wikidata.org/wiki/Q252857","display_name":"Transcriptome","level":4,"score":0.2976055145263672},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.26926612854003906},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.17785337567329407}],"mesh":[{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019869","descriptor_name":"Phosphatidylinositol 3-Kinases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020869","descriptor_name":"Gene Expression Profiling","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D045908","descriptor_name":"Mpox, Monkeypox","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D048868","descriptor_name":"Adaptor Proteins, Signal Transducing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.jiph.2023.10.035","doi":"https://doi.org/10.1016/j.jiph.2023.10.035","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jiph.2023.10.035","pdf_url":null,"source":{"id":"https://openalex.org/S53706017","display_name":"Journal of Infection and Public Health","issn_l":"1876-0341","issn":["1876-0341","1876-035X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Infection and Public Health","raw_type":"journal-article"},{"id":"pmid:37992435","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37992435","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of infection and public health","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:ff02e38a07b64440a6369eff933c4703","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/ff02e38a07b64440a6369eff933c4703","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Infection and Public Health, Vol 17, Iss 1, Pp 60-69 (2024)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.jiph.2023.10.035","doi":"https://doi.org/10.1016/j.jiph.2023.10.035","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.jiph.2023.10.035","pdf_url":null,"source":{"id":"https://openalex.org/S53706017","display_name":"Journal of Infection and Public Health","issn_l":"1876-0341","issn":["1876-0341","1876-035X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Infection and Public Health","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[{"id":"https://openalex.org/G123012238","display_name":null,"funder_award_id":"TMU-108-AE1-B16","funder_id":"https://openalex.org/F4320322814","funder_display_name":"Taipei Medical University"},{"id":"https://openalex.org/G3102948317","display_name":"Investigating the Mechanism of Pad4-Regulated Innate Immunity and the Effects on Tumor Microenvironment in Kras G12c\u2013Mutant Non\u2013Small Cell Lung Cancer","funder_award_id":"NSTC112-2320-B039-012-MY3","funder_id":"https://openalex.org/F2461203286","funder_display_name":"National Science and Technology Council"},{"id":"https://openalex.org/G5681394389","display_name":null,"funder_award_id":"CMU112-MF-64","funder_id":"https://openalex.org/F4320324301","funder_display_name":"China Medical University"},{"id":"https://openalex.org/G7133727216","display_name":"Investigating Potential Therapeutic Targets of Amino Acid Metabolism in Temozolomide -Resistance and Relapse Glioblastoma Patients","funder_award_id":"NSTC112-2320-B038-024","funder_id":"https://openalex.org/F2461203286","funder_display_name":"National Science and Technology Council"}],"funders":[{"id":"https://openalex.org/F2461203286","display_name":"National Science and Technology Council","ror":"https://ror.org/02kv4zf79"},{"id":"https://openalex.org/F4320311687","display_name":"Ministry of Education","ror":"https://ror.org/03m01yf64"},{"id":"https://openalex.org/F4320322814","display_name":"Taipei Medical University","ror":"https://ror.org/05031qk94"},{"id":"https://openalex.org/F4320324301","display_name":"China Medical University","ror":"https://ror.org/032d4f246"},{"id":"https://openalex.org/F4320337244","display_name":"Office of Research and Development, Taipei Medical University","ror":null}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W1495352559","https://openalex.org/W1835915349","https://openalex.org/W1969696177","https://openalex.org/W2024621976","https://openalex.org/W2041250281","https://openalex.org/W2042370230","https://openalex.org/W2045949302","https://openalex.org/W2090210387","https://openalex.org/W2091517553","https://openalex.org/W2103017472","https://openalex.org/W2121413357","https://openalex.org/W2129386720","https://openalex.org/W2133465414","https://openalex.org/W2148045713","https://openalex.org/W2158217645","https://openalex.org/W2160697532","https://openalex.org/W2593884101","https://openalex.org/W2755705685","https://openalex.org/W2779910850","https://openalex.org/W2979892275","https://openalex.org/W3013449264","https://openalex.org/W3013576850","https://openalex.org/W3015300099","https://openalex.org/W3036550958","https://openalex.org/W3040570743","https://openalex.org/W3089928807","https://openalex.org/W3107527779","https://openalex.org/W3139347754","https://openalex.org/W3142505684","https://openalex.org/W3190074803","https://openalex.org/W4200097777","https://openalex.org/W4205943929","https://openalex.org/W4210259460","https://openalex.org/W4211060053","https://openalex.org/W4223930334","https://openalex.org/W4234185093","https://openalex.org/W4281622731","https://openalex.org/W4281694059","https://openalex.org/W4281710382","https://openalex.org/W4281843992","https://openalex.org/W4283272990","https://openalex.org/W4283381433","https://openalex.org/W4283445814","https://openalex.org/W4284879549","https://openalex.org/W4286383196","https://openalex.org/W4288687355","https://openalex.org/W4290079393","https://openalex.org/W4293659866","https://openalex.org/W4294675789","https://openalex.org/W4295759519","https://openalex.org/W4298326672","https://openalex.org/W4307066779","https://openalex.org/W4310796693","https://openalex.org/W4310928040","https://openalex.org/W4311855686","https://openalex.org/W4313656380","https://openalex.org/W4321607831"],"related_works":["https://openalex.org/W4294121151","https://openalex.org/W2128633905","https://openalex.org/W4414615954","https://openalex.org/W4396240220","https://openalex.org/W7111154265","https://openalex.org/W7168268141","https://openalex.org/W4401410922","https://openalex.org/W4415997857","https://openalex.org/W4361011399","https://openalex.org/W7130703517"],"abstract_inverted_index":{"BACKGROUND:":[0],"The":[1,20,103],"recent":[2],"re-emergence":[3],"of":[4,87,105,112,169,191,235,264,273,284],"the":[5,30,42,93,106,179,189,223,233,265,268,281],"monkeypox":[6],"(mpox)":[7],"epidemic":[8],"in":[9,131],"nonendemic":[10],"regions":[11],"has":[12],"raised":[13],"concerns":[14],"regarding":[15],"a":[16,25],"potential":[17],"global":[18],"outbreak.":[19],"mpox":[21],"virus":[22,27],"(MPV)":[23],"is":[24],"smallpox-like":[26],"belonging":[28],"to":[29,91,128,212,219],"genus":[31],"Orthopoxvirus":[32],"(family:":[33],"Poxviridae).":[34],"Although":[35],"studies":[36],"suggest":[37],"that":[38],"MPV":[39,52,100,136,285],"infection":[40,181,225],"suppresses":[41],"Toll-like":[43],"receptor-3-":[44],"and":[45,84,96,114,117,139,161,167,171,205,209,214,255,270],"tumor":[46],"necrosis":[47],"factor-\u03b1-related":[48],"signaling":[49],"pathways,":[50],"whether":[51],"regulates":[53],"other":[54],"immune-related":[55],"pathways":[56,97,125,143,168,210],"remains":[57],"unclear.":[58],"METHODS:":[59],"In":[60],"this":[61],"study,":[62],"two":[63,81],"distinct":[64],"temporal":[65],"patterns":[66],"were":[67,89,126,175,217],"used":[68],"for":[69,137],"establishing":[70],"an":[71],"MPV-infected":[72],"human":[73],"immortal":[74],"epithelial":[75],"cancer":[76],"cell":[77,215],"line":[78],"(HeLa).":[79],"These":[80,142],"durations":[82],"2":[83,138],"12":[85,140],"h":[86],"incubation":[88],"selected":[90],"identify":[92],"coregulated":[94],"genes":[95,192,236],"affected":[98],"by":[99],"infection.":[101,286],"RESULTS:":[102],"use":[104],"Gene":[107],"Ontology":[108],"framework,":[109],"Kyoto":[110],"Encyclopedia":[111],"Genes":[113],"Genome":[115],"database,":[116],"MetaCore":[118],"software":[119],"yielded":[120],"valuable":[121,278],"insights.":[122],"Specifically,":[123],"various":[124,282],"found":[127,218],"be":[129,220],"enriched":[130],"HeLa":[132],"cells":[133],"infected":[134],"with":[135,178,222],"h.":[141],"included":[144],"Notch,":[145],"CD40,":[146],"CD95,":[147],"hypoxia-inducible":[148],"factor-1-\u03b1,":[149],"interleukin":[150],"(IL)-":[151],"1,":[152],"IL-6,":[153],"phosphoinositide":[154],"3-kinase,":[155],"nuclear":[156],"factor-\u03baB,":[157],"mitogen-activated":[158],"protein":[159],"kinase,":[160],"oxidative":[162],"stress-induced":[163],"signalling":[164],"pathways.":[165],"Clusters":[166],"metabolism":[170],"viral":[172],"replication":[173],"cycles":[174],"significantly":[176],"associated":[177,221],"2-hour":[180],"group.":[182,226],"This":[183,227,258],"association":[184,228],"was":[185,229],"identified":[186,230],"based":[187,231],"on":[188,232],"regulation":[190,234],"such":[193,237],"as":[194,238],"HSPG2,":[195],"RHPN2,":[196],"MYL1,":[197],"ASPHD2,":[198],"CA9,":[199],"VIPR1,":[200],"SNX12,":[201],"MGC2752,":[202],"SLC25A1,":[203],"PEX19,":[204],"AREG.":[206],"Furthermore,":[207],"clusters":[208],"related":[211],"immunity":[213],"movement":[216],"12-hour":[224],"C1orf21,":[239],"C19orf48,":[240],"HRK,":[241],"IL8,":[242],"GULP1,":[243],"SCAND2,":[244],"ATP5C1,":[245],"FEZ1,":[246],"SGSH,":[247],"TACC2,":[248],"CYP4X1,":[249],"MMP1,":[250],"CPB1,":[251],"P2RY13,":[252],"WDR27,":[253],"PRPF4,":[254],"ENDOD1.":[256],"CONCLUSIONS:":[257],"study":[259],"can":[260],"improve":[261],"our":[262],"understanding":[263],"mechanisms":[266],"underlying":[267],"pathophysiology":[269],"post-infection":[271],"sequelae":[272],"mpox.":[274],"Our":[275],"findings":[276],"provide":[277],"insights":[279],"into":[280],"modes":[283]},"counts_by_year":[{"year":2026,"cited_by_count":13},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":4}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2023-11-03T00:00:00"}