{"id":"https://openalex.org/W4388127673","doi":"https://doi.org/10.1097/ccm.0000000000006092","title":"The Relationship Between Metabolic Syndrome and Mortality Among Patients With Acute Respiratory Distress Syndrome in Acute Respiratory Distress Syndrome Network and Prevention and Early Treatment of Acute Lung Injury Network Trials*","display_name":"The Relationship Between Metabolic Syndrome and Mortality Among Patients With Acute Respiratory Distress Syndrome in Acute Respiratory Distress Syndrome Network and Prevention and Early Treatment of Acute Lung Injury Network Trials*","publication_year":2023,"publication_date":"2023-11-01","ids":{"openalex":"https://openalex.org/W4388127673","doi":"https://doi.org/10.1097/ccm.0000000000006092","pmid":"https://pubmed.ncbi.nlm.nih.gov/37909824"},"language":"en","primary_location":{"id":"doi:10.1097/ccm.0000000000006092","doi":"https://doi.org/10.1097/ccm.0000000000006092","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ccm.0000000000006092","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10922467/pdf/nihms-1936011.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114098864","display_name":"Kevin Tea","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kevin Tea","raw_affiliation_strings":["Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056513449","display_name":"Yuanhao Zu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yuanhao Zu","raw_affiliation_strings":["Department of Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103356920","display_name":"Cheng Han Chung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cheng Han Chung","raw_affiliation_strings":["Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057776191","display_name":"Jaclyn A. Pagliaro","orcid":"https://orcid.org/0000-0003-4289-3073","observed_orcids":["https://orcid.org/0000-0003-4289-3073"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jaclyn Pagliaro","raw_affiliation_strings":["Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Diana Espinoza-Barrera","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Diana Espinoza-Barrera","raw_affiliation_strings":["Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065023404","display_name":"Prakriti Mehta","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Prakriti Mehta","raw_affiliation_strings":["Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084368387","display_name":"Himmat Grewal","orcid":"https://orcid.org/0000-0002-4260-2865","observed_orcids":["https://orcid.org/0000-0002-4260-2865"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Himmat Grewal","raw_affiliation_strings":["Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083870849","display_name":"Ivor S. Douglas","orcid":"https://orcid.org/0000-0002-4541-1431","observed_orcids":["https://orcid.org/0000-0002-4541-1431"]},"institutions":[{"id":"https://openalex.org/I2801983979","display_name":"Denver Health Medical Center","ror":"https://ror.org/01fbz6h17","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2801983979"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ivor S. Douglas","raw_affiliation_strings":["Division of Pulmonary Sciences and Critical Care Medicine, Denver Health Medical Center, Denver, CO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pulmonary Sciences and Critical Care Medicine, Denver Health Medical Center, Denver, CO","institution_ids":["https://openalex.org/I2801983979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102855467","display_name":"Yas\u00edn A. Khan","orcid":"https://orcid.org/0000-0002-0426-1780","observed_orcids":["https://orcid.org/0000-0002-0426-1780"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]},{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]}],"countries":["CA","US"],"is_corresponding":false,"raw_author_name":"Yasin A. Khan","raw_affiliation_strings":["Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada","Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada","institution_ids":["https://openalex.org/I185261750"]},{"raw_affiliation_string":"Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049957635","display_name":"Jeffrey G. Shaffer","orcid":"https://orcid.org/0000-0002-3941-3772","observed_orcids":["https://orcid.org/0000-0002-3941-3772"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeffrey G. Shaffer","raw_affiliation_strings":["Department of Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biostatistics and Data Science, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010086010","display_name":"Joshua Lee Denson","orcid":"https://orcid.org/0000-0002-8654-7765","observed_orcids":["https://orcid.org/0000-0002-8654-7765"]},"institutions":[{"id":"https://openalex.org/I114832834","display_name":"Tulane University","ror":"https://ror.org/04vmvtb21","country_code":"US","type":"education","lineage":["https://openalex.org/I114832834"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joshua L. Denson","raw_affiliation_strings":["Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Pulmonary Diseases, Critical Care, and Environmental Medicine, Deming Department of Medicine, Tulane University School of Medicine, New Orleans, LA","institution_ids":["https://openalex.org/I114832834"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1067,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.78943418,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":97},"biblio":{"volume":"52","issue":"3","first_page":"407","last_page":"419"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/metabolic-syndrome","display_name":"metabolic syndrome","score":0.8759999871253967},{"id":"https://openalex.org/keywords/acute-respiratory-distress-syndrome","display_name":"acute respiratory distress syndrome","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.9110000133514404},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8740000128746033},{"id":"https://openalex.org/keywords/diabetes-mellitus","display_name":"diabetes mellitus","score":0.9769999980926514},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":1.0},{"id":"https://openalex.org/keywords/ards-etiology","display_name":"ARDS etiology","score":0.843999981880188},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.8999999761581421},{"id":"https://openalex.org/keywords/pneumonia","display_name":"pneumonia","score":0.9660000205039978},{"id":"https://openalex.org/keywords/28-day-mortality","display_name":"28-day mortality","score":0.7210000157356262},{"id":"https://openalex.org/keywords/90-day-mortality","display_name":"90-day mortality","score":0.8740000128746033},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.6629999876022339}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9552780389785767},{"id":"https://openalex.org/C2909621147","wikidata":"https://www.wikidata.org/wiki/Q344873","display_name":"Acute respiratory distress","level":3,"score":0.817419707775116},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5493624806404114},{"id":"https://openalex.org/C9418649","wikidata":"https://www.wikidata.org/wiki/Q5275407","display_name":"Diffuse alveolar damage","level":4,"score":0.48892584443092346},{"id":"https://openalex.org/C141983124","wikidata":"https://www.wikidata.org/wiki/Q188008","display_name":"Respiratory distress","level":2,"score":0.4881480634212494},{"id":"https://openalex.org/C534529494","wikidata":"https://www.wikidata.org/wiki/Q7891","display_name":"Respiratory system","level":2,"score":0.45617836713790894},{"id":"https://openalex.org/C2780578515","wikidata":"https://www.wikidata.org/wiki/Q657193","display_name":"Metabolic syndrome","level":3,"score":0.4219599962234497},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.30014747381210327},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.2376188039779663},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.2025366723537445},{"id":"https://openalex.org/C511355011","wikidata":"https://www.wikidata.org/wiki/Q12174","display_name":"Obesity","level":2,"score":0.04962339997291565}],"mesh":[{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012128","descriptor_name":"Respiratory Distress Syndrome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012128","descriptor_name":"Respiratory Distress Syndrome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012128","descriptor_name":"Respiratory Distress Syndrome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012128","descriptor_name":"Respiratory Distress Syndrome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012128","descriptor_name":"Respiratory Distress Syndrome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012128","descriptor_name":"Respiratory Distress Syndrome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012128","descriptor_name":"Respiratory Distress Syndrome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D024821","descriptor_name":"Metabolic Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D055371","descriptor_name":"Acute Lung Injury","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055371","descriptor_name":"Acute Lung Injury","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055371","descriptor_name":"Acute Lung Injury","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055371","descriptor_name":"Acute Lung Injury","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055371","descriptor_name":"Acute Lung Injury","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055371","descriptor_name":"Acute Lung Injury","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D055371","descriptor_name":"Acute Lung Injury","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1097/ccm.0000000000006092","doi":"https://doi.org/10.1097/ccm.0000000000006092","is_oa":false,"landing_page_url":"https://doi.org/10.1097/ccm.0000000000006092","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},{"id":"pmid:37909824","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37909824","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical care medicine","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10922467","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10922467","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10922467/pdf/nihms-1936011.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Crit Care Med","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:10922467","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10922467","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10922467/pdf/nihms-1936011.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Crit Care Med","raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.8999999761581421,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1937633654","display_name":null,"funder_award_id":"U54\u2010 GM104940","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000898112","display_name":"Louisiana Clinical and Translational Science Center","funder_award_id":"5u54gm104940-10","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4388127673.pdf","grobid_xml":"https://content.openalex.org/works/W4388127673.grobid-xml"},"referenced_works_count":41,"referenced_works":["https://openalex.org/W1803784511","https://openalex.org/W1983463791","https://openalex.org/W1997255681","https://openalex.org/W1997700012","https://openalex.org/W1998331580","https://openalex.org/W2013401250","https://openalex.org/W2028053287","https://openalex.org/W2028791968","https://openalex.org/W2043355764","https://openalex.org/W2043910070","https://openalex.org/W2056193118","https://openalex.org/W2062756785","https://openalex.org/W2068854215","https://openalex.org/W2074552958","https://openalex.org/W2098582236","https://openalex.org/W2102501066","https://openalex.org/W2103714496","https://openalex.org/W2116663073","https://openalex.org/W2124519382","https://openalex.org/W2145697808","https://openalex.org/W2149639841","https://openalex.org/W2154072741","https://openalex.org/W2160722967","https://openalex.org/W2286228001","https://openalex.org/W2314787815","https://openalex.org/W2320873518","https://openalex.org/W2322392387","https://openalex.org/W2333411966","https://openalex.org/W2407067283","https://openalex.org/W2523938811","https://openalex.org/W2620241325","https://openalex.org/W2920258695","https://openalex.org/W2930928131","https://openalex.org/W2944755457","https://openalex.org/W2978795816","https://openalex.org/W2998886261","https://openalex.org/W3035808329","https://openalex.org/W3080307554","https://openalex.org/W3181379278","https://openalex.org/W4200303215","https://openalex.org/W4237939525"],"related_works":["https://openalex.org/W2046138513","https://openalex.org/W3093204641","https://openalex.org/W2325602398","https://openalex.org/W2992997238","https://openalex.org/W1989076008","https://openalex.org/W4256656287","https://openalex.org/W2079874473","https://openalex.org/W4256743973","https://openalex.org/W382641583","https://openalex.org/W2468398407"],"abstract_inverted_index":{"OBJECTIVES:":[0],"Metabolic":[1,267],"syndrome":[2,13,32,89,103,131,143,203,268],"is":[3],"known":[4],"to":[5,26,178,295],"predict":[6],"outcomes":[7],"in":[8,20,206,231,269,279,298],"COVID-19":[9],"acute":[10],"respiratory":[11],"distress":[12],"(ARDS)":[14],"but":[15,229],"has":[16],"never":[17],"been":[18],"studied":[19],"non-COVID-19":[21,280],"ARDS.":[22,281],"We":[23],"therefore":[24],"aimed":[25],"determine":[27],"the":[28,72,141],"association":[29],"of":[30,43,64,277],"metabolic":[31,88,102,130,142,174,202,285],"with":[33,85,98,105,129,134,147,155,273],"mortality":[34,152,182,198,278],"among":[35],"ARDS":[36,44,57,86,124,196,207,232,270,288],"trial":[37,125],"subjects.":[38],"DESIGN:":[39],"Retrospective":[40],"cohort":[41],"study":[42],"trials'":[45],"data.":[46],"SETTING:":[47],"An":[48],"ancillary":[49],"analysis":[50],"was":[51,119,145,183,199,271],"conducted":[52],"using":[53],"data":[54],"from":[55,176,233],"seven":[56],"Network":[58,68],"and":[59,61,75,87,94,150,165,188,221,244,256,262,287],"Prevention":[60],"Early":[62],"Treatment":[63],"Acute":[65],"Lung":[66],"Injury":[67],"randomized":[69],"trials":[70],"within":[71],"Biologic":[73],"Specimen":[74],"Data":[76],"Repository":[77],"Information":[78],"Coordinating":[79],"Center":[80],"database.":[81],"PATIENTS:":[82],"Hospitalized":[83],"patients":[84,100],"(defined":[90],"by":[91,185,195,209],"obesity,":[92],"diabetes,":[93],"hypertension)":[95],"were":[96,132],"compared":[97,133,154],"similar":[99],"without":[101],"(those":[104],"less":[106],"than":[107],"three":[108],"criteria).":[109],"INTERVENTIONS:":[110],"None.":[111],"MEASUREMENTS":[112],"AND":[113],"MAIN":[114],"RESULTS:":[115],"The":[116,282],"primary":[117],"outcome":[118],"28-day":[120,149,181],"mortality.":[121],"Among":[122],"4288":[123],"participants,":[126],"454":[127],"(10.6%)":[128],"3834":[135],"controls":[136],"(89.4%).":[137],"In":[138,191],"adjusted":[139,180],"analyses,":[140],"group":[144],"associated":[146,272],"lower":[148,200,275],"90-day":[151,263],"when":[153],"control":[156,205],"(adjusted":[157],"odds":[158],"ratio":[159],"[aOR],":[160],"0.70":[161],"[95%":[162,167,218,226,241,249],"CI,":[163,168,219,227,242,250],"0.55-0.89]":[164],"0.75":[166],"0.60-0.95],":[169],"respectively).":[170],"With":[171],"each":[172],"additional":[173],"criterion":[175],"0":[177],"3,":[179],"reduced":[184],"18%,":[186],"22%,":[187],"40%,":[189],"respectively.":[190,265],"subgroup":[192],"analyses":[193],"stratifying":[194],"etiology,":[197],"for":[201,260],"vs.":[204],"caused":[208],"sepsis":[210],"or":[211],"pneumonia":[212],"(at":[213,236],"28":[214,237],"d,":[215,223,238,246],"aOR":[216,224,239,247],"0.64":[217],"0.48-0.84]":[220],"90":[222,245],"0.69":[225],"0.53-0.89]),":[228],"not":[230],"noninfectious":[234],"causes":[235],"1.18":[240],"0.70-1.99]":[243],"1.26":[248],"0.77-2.06]).":[251],"Interaction":[252],"p":[253,257],"=":[254,258],"0.04":[255],"0.02":[259],"28-":[261],"comparisons,":[264],"CONCLUSIONS:":[266],"a":[274,291],"risk":[276],"relationship":[283],"between":[284],"inflammation":[286],"may":[289],"provide":[290],"novel":[292],"biological":[293],"pathway":[294],"be":[296],"explored":[297],"precision":[299],"medicine-based":[300],"trials.":[301]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2025-10-10T00:00:00"}