{"id":"https://openalex.org/W4388114686","doi":"https://doi.org/10.1016/j.freeradbiomed.2023.10.169","title":"Mitochondrial dysfunction in animal model of severe acute neonatal hypoxia: effect of the NOS inhibitor, 2-iminobiotin.","display_name":"Mitochondrial dysfunction in animal model of severe acute neonatal hypoxia: effect of the NOS inhibitor, 2-iminobiotin.","publication_year":2023,"publication_date":"2023-11-01","ids":{"openalex":"https://openalex.org/W4388114686","doi":"https://doi.org/10.1016/j.freeradbiomed.2023.10.169"},"language":"en","primary_location":{"id":"doi:10.1016/j.freeradbiomed.2023.10.169","doi":"https://doi.org/10.1016/j.freeradbiomed.2023.10.169","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.freeradbiomed.2023.10.169","pdf_url":null,"source":{"id":"https://openalex.org/S128018148","display_name":"Free Radical Biology and Medicine","issn_l":"0891-5849","issn":["0891-5849","1873-4596"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Free Radical Biology and Medicine","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040761349","display_name":"Marianela Rodr\u00edguez-Rey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180910786","display_name":"Universidad de la Rep\u00fablica de Uruguay","ror":"https://ror.org/030bbe882","country_code":"UY","type":"education","lineage":["https://openalex.org/I180910786"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Marianela Rodriguez-Rey","raw_affiliation_strings":["Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay","institution_ids":["https://openalex.org/I180910786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068163510","display_name":"Valeria Valez","orcid":"https://orcid.org/0000-0001-5937-0215","observed_orcids":["https://orcid.org/0000-0001-5937-0215"]},"institutions":[{"id":"https://openalex.org/I180910786","display_name":"Universidad de la Rep\u00fablica de Uruguay","ror":"https://ror.org/030bbe882","country_code":"UY","type":"education","lineage":["https://openalex.org/I180910786"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Valeria Valez","raw_affiliation_strings":["Bioqu\u00edmica and CEINBIO, Facultad de Odontolog\u00eda, Universidad de la Rep\u00fablica, Uruguay, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bioqu\u00edmica and CEINBIO, Facultad de Odontolog\u00eda, Universidad de la Rep\u00fablica, Uruguay, Montevideo, Uruguay","institution_ids":["https://openalex.org/I180910786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004035319","display_name":"Pilar Abella","orcid":"https://orcid.org/0000-0002-8794-0374","observed_orcids":["https://orcid.org/0000-0002-8794-0374"]},"institutions":[{"id":"https://openalex.org/I180910786","display_name":"Universidad de la Rep\u00fablica de Uruguay","ror":"https://ror.org/030bbe882","country_code":"UY","type":"education","lineage":["https://openalex.org/I180910786"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Pilar Abella","raw_affiliation_strings":["Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay","institution_ids":["https://openalex.org/I180910786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034336155","display_name":"Soledad Marton","orcid":"https://orcid.org/0000-0001-9007-3104","observed_orcids":["https://orcid.org/0000-0001-9007-3104"]},"institutions":[{"id":"https://openalex.org/I180910786","display_name":"Universidad de la Rep\u00fablica de Uruguay","ror":"https://ror.org/030bbe882","country_code":"UY","type":"education","lineage":["https://openalex.org/I180910786"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Soledad Marton","raw_affiliation_strings":["Dpto. Histolog\u00eda, Universidad de la Rep\u00fablica. Facultad de Medicina, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dpto. Histolog\u00eda, Universidad de la Rep\u00fablica. Facultad de Medicina, Uruguay","institution_ids":["https://openalex.org/I180910786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084232092","display_name":"An\u00edbal M. Reyes","orcid":"https://orcid.org/0000-0003-3911-4649","observed_orcids":["https://orcid.org/0000-0003-3911-4649"]},"institutions":[{"id":"https://openalex.org/I180910786","display_name":"Universidad de la Rep\u00fablica de Uruguay","ror":"https://ror.org/030bbe882","country_code":"UY","type":"education","lineage":["https://openalex.org/I180910786"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"An\u00edbal M. Reyes","raw_affiliation_strings":["Universidad de la Rep\u00fablica, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidad de la Rep\u00fablica, Montevideo, Uruguay","institution_ids":["https://openalex.org/I180910786"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Luc\u00eda Vaamoinde","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180910786","display_name":"Universidad de la Rep\u00fablica de Uruguay","ror":"https://ror.org/030bbe882","country_code":"UY","type":"education","lineage":["https://openalex.org/I180910786"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Luc\u00eda Vaamoinde","raw_affiliation_strings":["Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay","institution_ids":["https://openalex.org/I180910786"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Cecilia Fern\u00e1ndez","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180910786","display_name":"Universidad de la Rep\u00fablica de Uruguay","ror":"https://ror.org/030bbe882","country_code":"UY","type":"education","lineage":["https://openalex.org/I180910786"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Cecilia Fern\u00e1ndez","raw_affiliation_strings":["Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay","institution_ids":["https://openalex.org/I180910786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102712195","display_name":"Luc\u00eda Far\u00edas","orcid":"https://orcid.org/0000-0003-1609-5705","observed_orcids":["https://orcid.org/0000-0003-1609-5705"]},"institutions":[{"id":"https://openalex.org/I180910786","display_name":"Universidad de la Rep\u00fablica de Uruguay","ror":"https://ror.org/030bbe882","country_code":"UY","type":"education","lineage":["https://openalex.org/I180910786"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Luc\u00eda Far\u00edas","raw_affiliation_strings":["Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay","institution_ids":["https://openalex.org/I180910786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002148458","display_name":"T. Pina Cabral","orcid":"https://orcid.org/0000-0002-8252-4531","observed_orcids":["https://orcid.org/0000-0002-8252-4531"]},"institutions":[{"id":"https://openalex.org/I180910786","display_name":"Universidad de la Rep\u00fablica de Uruguay","ror":"https://ror.org/030bbe882","country_code":"UY","type":"education","lineage":["https://openalex.org/I180910786"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Tamara Cabral","raw_affiliation_strings":["Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay","institution_ids":["https://openalex.org/I180910786"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Bad\u00eda Mart\u00edn","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I180910786","display_name":"Universidad de la Rep\u00fablica de Uruguay","ror":"https://ror.org/030bbe882","country_code":"UY","type":"education","lineage":["https://openalex.org/I180910786"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Bad\u00eda Mart\u00edn","raw_affiliation_strings":["Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dpto. Neonatolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay","institution_ids":["https://openalex.org/I180910786"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016477405","display_name":"Fernanda Blasina","orcid":"https://orcid.org/0000-0001-6697-5570","observed_orcids":["https://orcid.org/0000-0001-6697-5570"]},"institutions":[{"id":"https://openalex.org/I180910786","display_name":"Universidad de la Rep\u00fablica de Uruguay","ror":"https://ror.org/030bbe882","country_code":"UY","type":"education","lineage":["https://openalex.org/I180910786"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Fernanda Blasina","raw_affiliation_strings":["Dpto. Histolog\u00eda, Universidad de la Rep\u00fablica. Facultad de Medicina, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dpto. Histolog\u00eda, Universidad de la Rep\u00fablica. Facultad de Medicina, Uruguay","institution_ids":["https://openalex.org/I180910786"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073926538","display_name":"Rafael Rad\u00ed","orcid":"https://orcid.org/0000-0002-1114-1875","observed_orcids":["https://orcid.org/0000-0002-1114-1875"]},"institutions":[{"id":"https://openalex.org/I180910786","display_name":"Universidad de la Rep\u00fablica de Uruguay","ror":"https://ror.org/030bbe882","country_code":"UY","type":"education","lineage":["https://openalex.org/I180910786"]}],"countries":["UY"],"is_corresponding":false,"raw_author_name":"Rafael Radi","raw_affiliation_strings":["Universidad de la Rep\u00fablica, Montevideo, Uruguay"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universidad de la Rep\u00fablica, Montevideo, Uruguay","institution_ids":["https://openalex.org/I180910786"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I180910786"],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11046225,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"208","issue":null,"first_page":"S75","last_page":"S75"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.6675000190734863,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.6675000190734863,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11184","display_name":"Neonatal and fetal brain pathology","score":0.24459999799728394,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11057","display_name":"Cardiac Ischemia and Reperfusion","score":0.017999999225139618,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mitochondrial-dysfunction","display_name":"mitochondrial dysfunction","score":0.9980000257492065},{"id":"https://openalex.org/keywords/neonatal-hypoxia","display_name":"neonatal hypoxia","score":0.968999981880188},{"id":"https://openalex.org/keywords/nitric-oxide-synthase-inhibition","display_name":"nitric oxide synthase inhibition","score":0.9369999766349792},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.675000011920929},{"id":"https://openalex.org/keywords/animal-models","display_name":"animal models","score":0.5109999775886536},{"id":"https://openalex.org/keywords/neonatal-brain-injury","display_name":"neonatal brain injury","score":0.5720000267028809}],"concepts":[{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.6110456585884094},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40644896030426025},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39853718876838684},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.370646208524704},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3464832305908203},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.15311893820762634},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.freeradbiomed.2023.10.169","doi":"https://doi.org/10.1016/j.freeradbiomed.2023.10.169","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.freeradbiomed.2023.10.169","pdf_url":null,"source":{"id":"https://openalex.org/S128018148","display_name":"Free Radical Biology and Medicine","issn_l":"0891-5849","issn":["0891-5849","1873-4596"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Free Radical Biology and Medicine","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1993727732","https://openalex.org/W2743000446","https://openalex.org/W3150297780","https://openalex.org/W2418916898","https://openalex.org/W2318459750","https://openalex.org/W1974712759","https://openalex.org/W4214639809","https://openalex.org/W2098722149","https://openalex.org/W2085723125","https://openalex.org/W1977575860"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2023-11-02T00:00:00"}