{"id":"https://openalex.org/W4387979505","doi":"https://doi.org/10.1183/13993003.congress-2023.pa2164","title":"Epidemiological Trends in Nontuberculous Mycobacterial Infection among People with Cystic Fibrosis in Germany","display_name":"Epidemiological Trends in Nontuberculous Mycobacterial Infection among People with Cystic Fibrosis in Germany","publication_year":2023,"publication_date":"2023-09-09","ids":{"openalex":"https://openalex.org/W4387979505","doi":"https://doi.org/10.1183/13993003.congress-2023.pa2164"},"language":"en","primary_location":{"id":"doi:10.1183/13993003.congress-2023.pa2164","doi":"https://doi.org/10.1183/13993003.congress-2023.pa2164","is_oa":false,"landing_page_url":"https://doi.org/10.1183/13993003.congress-2023.pa2164","pdf_url":null,"source":{"id":"https://openalex.org/S4210207896","display_name":"European Respiratory Journal","issn_l":"0903-1936","issn":["0903-1936","1399-3003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317833","host_organization_name":"European Respiratory Society","host_organization_lineage":["https://openalex.org/P4310317833"],"host_organization_lineage_names":["European Respiratory Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tuberculosis and non-tuberculous mycobacterial diseases","raw_type":"proceedings-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035286425","display_name":"Mathis Steindor","orcid":"https://orcid.org/0000-0003-2724-5297","observed_orcids":["https://orcid.org/0000-0003-2724-5297"]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Mathis Steindor","raw_affiliation_strings":["Pediatric Pulmonology and Sleep Medicine, Children's University Hospital Essen, University of Duisburg-Essen, Essen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Pulmonology and Sleep Medicine, Children's University Hospital Essen, University of Duisburg-Essen, Essen, Germany","institution_ids":["https://openalex.org/I62318514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065077936","display_name":"Sylvia Hafkemeyer","orcid":"https://orcid.org/0000-0003-1221-9643","observed_orcids":["https://orcid.org/0000-0003-1221-9643"]},"institutions":[{"id":"https://openalex.org/I4210115300","display_name":"The Cystic Fibrosis Institute","ror":"https://ror.org/028ew8k17","country_code":"DE","type":"nonprofit","lineage":["https://openalex.org/I4210115300"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Sylvia Hafkemeyer","raw_affiliation_strings":["Mukoviszidose Institut gGmbH, Bonn, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mukoviszidose Institut gGmbH, Bonn, Germany","institution_ids":["https://openalex.org/I4210115300"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064692134","display_name":"Christian Ruckes","orcid":"https://orcid.org/0000-0003-4823-0430","observed_orcids":["https://orcid.org/0000-0003-4823-0430"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christian Ruckes","raw_affiliation_strings":["Interdisciplinary Center for Clinical Trials MainzInstitut gGmbH, Mainz, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Interdisciplinary Center for Clinical Trials MainzInstitut gGmbH, Mainz, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089485313","display_name":"Florian Stehling","orcid":"https://orcid.org/0000-0002-2417-2048","observed_orcids":["https://orcid.org/0000-0002-2417-2048"]},"institutions":[{"id":"https://openalex.org/I62318514","display_name":"University of Duisburg-Essen","ror":"https://ror.org/04mz5ra38","country_code":"DE","type":"education","lineage":["https://openalex.org/I62318514"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Florian Stehling","raw_affiliation_strings":["Pediatric Pulmonology and Sleep Medicine, Children's University Hospital Essen, University of Duisburg-Essen, Essen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatric Pulmonology and Sleep Medicine, Children's University Hospital Essen, University of Duisburg-Essen, Essen, Germany","institution_ids":["https://openalex.org/I62318514"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054782953","display_name":"Lutz Naehrlich","orcid":"https://orcid.org/0000-0002-7146-6997","observed_orcids":["https://orcid.org/0000-0002-7146-6997"]},"institutions":[{"id":"https://openalex.org/I200763008","display_name":"Justus-Liebig-Universit\u00e4t Gie\u00dfen","ror":"https://ror.org/033eqas34","country_code":"DE","type":"education","lineage":["https://openalex.org/I200763008"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Lutz Naehrlich","raw_affiliation_strings":["Department of Pediatrics, Justus-Liebig-University Giessen, Giessen, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Justus-Liebig-University Giessen, Giessen, Germany","institution_ids":["https://openalex.org/I200763008"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044665781","display_name":"Felix C. Ringshausen","orcid":"https://orcid.org/0000-0001-9084-4968","observed_orcids":["https://orcid.org/0000-0001-9084-4968"]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]},{"id":"https://openalex.org/I4210129183","display_name":"German Center for Lung Research","ror":"https://ror.org/03dx11k66","country_code":"DE","type":"facility","lineage":["https://openalex.org/I4210129183","https://openalex.org/I4405256427"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Felix C. Ringshausen","raw_affiliation_strings":["Department of Respiratory Medicine, Hannover Medical School and Biomedical Research in End-stage and Obstructive Lung disease (BREATH), German Center for Lung Research (DZL), Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Respiratory Medicine, Hannover Medical School and Biomedical Research in End-stage and Obstructive Lung disease (BREATH), German Center for Lung Research (DZL), Hannover, Germany","institution_ids":["https://openalex.org/I34809795","https://openalex.org/I4210129183"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"PA2164","last_page":"PA2164"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11316","display_name":"Mycobacterium research and diagnosis","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10665","display_name":"Cystic Fibrosis Research Advances","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12824","display_name":"Infections and bacterial resistance","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2726","display_name":"Microbiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nontuberculous-mycobacterial-infection","display_name":"nontuberculous mycobacterial infection","score":0.9139999747276306},{"id":"https://openalex.org/keywords/cystic-fibrosis","display_name":"cystic fibrosis","score":1.0},{"id":"https://openalex.org/keywords/mycobacterium-abscessus-complex","display_name":"Mycobacterium abscessus complex","score":0.9919999837875366},{"id":"https://openalex.org/keywords/mycobacterium-avium-complex","display_name":"Mycobacterium avium complex","score":0.9990000128746033},{"id":"https://openalex.org/keywords/mycobacterium-gordonae","display_name":"Mycobacterium gordonae","score":0.9589999914169312},{"id":"https://openalex.org/keywords/prevalence","display_name":"prevalence","score":0.6499999761581421},{"id":"https://openalex.org/keywords/incidence","display_name":"incidence","score":0.9990000128746033},{"id":"https://openalex.org/keywords/aspergillus-fumigatus","display_name":"Aspergillus fumigatus","score":0.9950000047683716},{"id":"https://openalex.org/keywords/allergic-bronchopulmonary-aspergillosis","display_name":"allergic bronchopulmonary aspergillosis","score":0.9980000257492065}],"concepts":[{"id":"https://openalex.org/C2778679867","wikidata":"https://www.wikidata.org/wiki/Q1881705","display_name":"Nontuberculous mycobacteria","level":4,"score":0.8571534156799316},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.720812201499939},{"id":"https://openalex.org/C107130276","wikidata":"https://www.wikidata.org/wiki/Q133805","display_name":"Epidemiology","level":2,"score":0.7005958557128906},{"id":"https://openalex.org/C2776938444","wikidata":"https://www.wikidata.org/wiki/Q178194","display_name":"Cystic fibrosis","level":2,"score":0.6985118389129639},{"id":"https://openalex.org/C61511704","wikidata":"https://www.wikidata.org/wiki/Q1671857","display_name":"Incidence (geometry)","level":2,"score":0.647506594657898},{"id":"https://openalex.org/C2781455004","wikidata":"https://www.wikidata.org/wiki/Q3311330","display_name":"Mycobacterium avium complex","level":2,"score":0.6284147500991821},{"id":"https://openalex.org/C2778871687","wikidata":"https://www.wikidata.org/wiki/Q1430844","display_name":"Allergic bronchopulmonary aspergillosis","level":4,"score":0.5234529376029968},{"id":"https://openalex.org/C2776111603","wikidata":"https://www.wikidata.org/wiki/Q6946978","display_name":"Mycobacterium abscessus","level":4,"score":0.49215930700302124},{"id":"https://openalex.org/C2779787849","wikidata":"https://www.wikidata.org/wiki/Q134359","display_name":"Aspergillus fumigatus","level":2,"score":0.45185935497283936},{"id":"https://openalex.org/C2776391196","wikidata":"https://www.wikidata.org/wiki/Q259626","display_name":"Aspergillosis","level":2,"score":0.43221598863601685},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.39995262026786804},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.38024619221687317},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.35834452509880066},{"id":"https://openalex.org/C2780374374","wikidata":"https://www.wikidata.org/wiki/Q194309","display_name":"Mycobacterium","level":3,"score":0.2701132595539093},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1794719696044922},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.0},{"id":"https://openalex.org/C141105273","wikidata":"https://www.wikidata.org/wiki/Q79455","display_name":"Immunoglobulin E","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1183/13993003.congress-2023.pa2164","doi":"https://doi.org/10.1183/13993003.congress-2023.pa2164","is_oa":false,"landing_page_url":"https://doi.org/10.1183/13993003.congress-2023.pa2164","pdf_url":null,"source":{"id":"https://openalex.org/S4210207896","display_name":"European Respiratory Journal","issn_l":"0903-1936","issn":["0903-1936","1399-3003"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310317833","host_organization_name":"European Respiratory Society","host_organization_lineage":["https://openalex.org/P4310317833"],"host_organization_lineage_names":["European Respiratory Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tuberculosis and non-tuberculous mycobacterial diseases","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4385225972","https://openalex.org/W2808656571","https://openalex.org/W2202104810","https://openalex.org/W7132929981","https://openalex.org/W2157752583","https://openalex.org/W4405484719","https://openalex.org/W4414428151","https://openalex.org/W6931872514","https://openalex.org/W2033513950","https://openalex.org/W2115087931"],"abstract_inverted_index":{"Background:":[0],"People":[1],"with":[2,11,72,138,150,158,185],"cystic":[3],"fibrosis":[4],"(pwCF)":[5],"are":[6,25],"at":[7],"risk":[8],"for":[9,41,132],"infection":[10,77,141,153],"nontuberculous":[12],"mycobacteria":[13,63],"(NTM).":[14],"Epidemiology":[15],"and":[16,46,61,66,75,85,91,97,172,187,195],"screening":[17],"practice":[18],"of":[19,32,48,116,127,192,200],"NTM":[20,83,134,162,196,201],"among":[21,100],"pwCF":[22,165],"in":[23,164,166],"Germany":[24,167],"largely":[26],"unknown.":[27],"Methods:":[28],"We":[29],"analyzed":[30],"data":[31],"the":[33,101,108,114,176],"German":[34],"CF":[35],"Registry":[36],"from":[37],"2016":[38,171],"to":[39,68,203],"2020":[40],"NTM.":[42,133],"The":[43,81,161,189],"annual":[44,82],"prevalence":[45,84,115],"incidence":[47,86],"any":[49],"NTM,":[50,111],"Mycobacterium":[51],"abscessus":[52],"complex":[53,57],"(MABC),":[54],"M.":[55,59],"avium":[56],"(MAC),":[58],"gordonae,":[60],"other":[62],"were":[64,78,130,136,154],"determined":[65],"correlated":[67],"patient":[69],"characteristics.":[70],"Patients":[71],"incident":[73,151],"MABC":[74,106,174],"MAC":[76,117,152,182],"compared.":[79],"Results:":[80],"remained":[87,168],"stable":[88],"between":[89,170],"7.53%":[90],"8.76%":[92],"as":[93,95],"well":[94],"3.31%":[96],"4.95%,":[98],"respectively,":[99],"approximately":[102],"6,000":[103],"registry":[104],"participants.":[105],"was":[107,175,197],"most":[109],"common":[110],"whereas":[112,180],"only":[113,123,181],"increased":[118,184],"slightly.":[119],"In":[120],"each":[121],"year,":[122],"about":[124],"one":[125],"third":[126],"all":[128],"patients":[129,149,157],"screened":[131],"infections":[135,183],"associated":[137],"Aspergillus":[139,193],"fumigatus":[140,194],"and/or":[142],"allergic":[143],"bronchopulmonary":[144],"aspergillosis":[145],"(ABPA).":[146],"On":[147],"average,":[148],"older":[155],"than":[156],"MABC.":[159],"Conclusions:":[160],"burden":[163],"unchanged":[169],"2020.":[173],"dominant":[177],"species":[178],"detected,":[179],"time":[186],"age.":[188],"known":[190],"association":[191],"reaffirmed.":[198],"Awareness":[199],"needs":[202],"be":[204],"improved.":[205]},"counts_by_year":[],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2023-10-28T00:00:00"}