{"id":"https://openalex.org/W4387969304","doi":"https://doi.org/10.1089/photob.2023.0021","title":"Development and Application of Prototype System Based on Light-Emitting Diode Arrays (660 nm) with a Top Hat Beam Profile in Order to Optimize Photobiomodulation Protocols for Treatment of Radiation-Induced Oral Mucositis in Rats","display_name":"Development and Application of Prototype System Based on Light-Emitting Diode Arrays (660 nm) with a Top Hat Beam Profile in Order to Optimize Photobiomodulation Protocols for Treatment of Radiation-Induced Oral Mucositis in Rats","publication_year":2023,"publication_date":"2023-10-27","ids":{"openalex":"https://openalex.org/W4387969304","doi":"https://doi.org/10.1089/photob.2023.0021","pmid":"https://pubmed.ncbi.nlm.nih.gov/37890115"},"language":"en","primary_location":{"id":"doi:10.1089/photob.2023.0021","doi":"https://doi.org/10.1089/photob.2023.0021","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1089/photob.2023.0021","pdf_url":null,"source":{"id":"https://openalex.org/S4210221680","display_name":"Photobiomodulation Photomedicine and Laser Surgery","issn_l":"2578-5478","issn":["2578-5478"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Photobiomodulation, Photomedicine, and Laser Surgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5029743486","display_name":"Alaba Tolulope Agbele","orcid":"https://orcid.org/0000-0002-8756-5754","observed_orcids":["https://orcid.org/0000-0002-8756-5754"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Alaba Tolulope Agbele","raw_affiliation_strings":["Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":"https://orcid.org/0000-0002-8756-5754","affiliations":[{"raw_affiliation_string":"Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034729928","display_name":"Ahmad Reza Dehpour","orcid":"https://orcid.org/0000-0002-8001-5565","observed_orcids":["https://orcid.org/0000-0002-8001-5565","https://orcid.org/0000-0001-5656-644X"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Ahmad Reza Dehpour","raw_affiliation_strings":["Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029077125","display_name":"Razieh Mohammad Jafari","orcid":"https://orcid.org/0000-0001-7082-0838","observed_orcids":["https://orcid.org/0000-0001-7082-0838"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Razieh Mohammad Jafari","raw_affiliation_strings":["Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012690210","display_name":"Seied Rabi Mahdavi","orcid":"https://orcid.org/0000-0003-1973-2140","observed_orcids":["https://orcid.org/0000-0003-1973-2140"]},"institutions":[{"id":"https://openalex.org/I204331812","display_name":"Guilan University of Medical Sciences","ror":"https://ror.org/04ptbrd12","country_code":"IR","type":"education","lineage":["https://openalex.org/I204331812","https://openalex.org/I4210110574"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Seyed Rabi Mehdi Mahdavi","raw_affiliation_strings":["Department of Cell Biology and Anatomy, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology and Anatomy, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran","institution_ids":["https://openalex.org/I204331812"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065081714","display_name":"Arash Elyassi","orcid":"https://orcid.org/0000-0001-6963-0084","observed_orcids":["https://orcid.org/0000-0001-6963-0084"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Arash Elyassi","raw_affiliation_strings":["Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075712697","display_name":"Mojtaba Seydi","orcid":"https://orcid.org/0000-0003-2456-329X","observed_orcids":["https://orcid.org/0000-0003-2456-329X"]},"institutions":[{"id":"https://openalex.org/I161106909","display_name":"Iran University of Medical Sciences","ror":"https://ror.org/03w04rv71","country_code":"IR","type":"education","lineage":["https://openalex.org/I161106909"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mojtaba Seydi","raw_affiliation_strings":["Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Physics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I161106909"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Mahmood Bagheri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Mahmood Bagheri","raw_affiliation_strings":["Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062198742","display_name":"Moein Ala","orcid":"https://orcid.org/0000-0001-5951-4864","observed_orcids":["https://orcid.org/0000-0001-5951-4864"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Moein Ala","raw_affiliation_strings":["Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Experimental Medicine Research Center, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109650004","display_name":"Babak Arji Roudsari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204331812","display_name":"Guilan University of Medical Sciences","ror":"https://ror.org/04ptbrd12","country_code":"IR","type":"education","lineage":["https://openalex.org/I204331812","https://openalex.org/I4210110574"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Babak Arji Roudsari","raw_affiliation_strings":["Department of Cell Biology and Anatomy, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cell Biology and Anatomy, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran","institution_ids":["https://openalex.org/I204331812"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5074423493","display_name":"Marjaneh Hejazi","orcid":"https://orcid.org/0000-0002-1823-2876","observed_orcids":["https://orcid.org/0000-0002-1823-2876"]},"institutions":[{"id":"https://openalex.org/I70640408","display_name":"Tehran University of Medical Sciences","ror":"https://ror.org/01c4pz451","country_code":"IR","type":"education","lineage":["https://openalex.org/I70640408"]}],"countries":["IR"],"is_corresponding":true,"raw_author_name":"Marjaneh Hejazi","raw_affiliation_strings":["Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Physics and Biomedical Engineering, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran","institution_ids":["https://openalex.org/I70640408"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5074423493"],"corresponding_institution_ids":["https://openalex.org/I70640408"],"apc_list":null,"apc_paid":null,"fwci":0.4147,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.50998405,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"41","issue":"11","first_page":"622","last_page":"631"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11566","display_name":"Laser Applications in Dentistry and Medicine","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11566","display_name":"Laser Applications in Dentistry and Medicine","score":0.9603999853134155,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12198","display_name":"Oral health in cancer treatment","score":0.0348999984562397,"subfield":{"id":"https://openalex.org/subfields/3500","display_name":"General Dentistry"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/low-level-laser-therapy","display_name":"low-level laser therapy","score":0.972000002861023},{"id":"https://openalex.org/keywords/radiation-induced-oral-mucositis","display_name":"radiation-induced oral mucositis","score":0.921999990940094},{"id":"https://openalex.org/keywords/head-and-neck-radiotherapy","display_name":"head and neck radiotherapy","score":0.6679999828338623},{"id":"https://openalex.org/keywords/led-arrays","display_name":"LED arrays","score":0.6449999809265137},{"id":"https://openalex.org/keywords/top-hat-beam-profile","display_name":"top-hat beam profile","score":0.9490000009536743},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.9660000205039978}],"concepts":[{"id":"https://openalex.org/C2778496288","wikidata":"https://www.wikidata.org/wiki/Q6931269","display_name":"Mucositis","level":3,"score":0.8489775657653809},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4823719561100006},{"id":"https://openalex.org/C65409693","wikidata":"https://www.wikidata.org/wiki/Q425265","display_name":"Statistical significance","level":2,"score":0.45399010181427},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.43109130859375},{"id":"https://openalex.org/C2778023920","wikidata":"https://www.wikidata.org/wiki/Q1872556","display_name":"Low level laser therapy","level":4,"score":0.42814841866493225},{"id":"https://openalex.org/C34439696","wikidata":"https://www.wikidata.org/wiki/Q95539","display_name":"Cheek pouch","level":3,"score":0.41338419914245605},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.3965756297111511},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.3556750416755676},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.34626924991607666},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.28049609065055847},{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.25912198424339294},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.22476336359977722},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13433951139450073},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.12546956539154053},{"id":"https://openalex.org/C2993195213","wikidata":"https://www.wikidata.org/wiki/Q851186","display_name":"Laser therapy","level":3,"score":0.08581307530403137},{"id":"https://openalex.org/C2778575167","wikidata":"https://www.wikidata.org/wiki/Q6573","display_name":"Hamster","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013280","descriptor_name":"Stomatitis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D013280","descriptor_name":"Stomatitis","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D016207","descriptor_name":"Cytokines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D028022","descriptor_name":"Low-Level Light Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064420","descriptor_name":"Drug-Related Side Effects and Adverse Reactions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1089/photob.2023.0021","doi":"https://doi.org/10.1089/photob.2023.0021","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1089/photob.2023.0021","pdf_url":null,"source":{"id":"https://openalex.org/S4210221680","display_name":"Photobiomodulation Photomedicine and Laser Surgery","issn_l":"2578-5478","issn":["2578-5478"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320443","host_organization_name":"Mary Ann Liebert, Inc.","host_organization_lineage":["https://openalex.org/P4310320443","https://openalex.org/P4310320017"],"host_organization_lineage_names":["Mary Ann Liebert, Inc.","SAGE Publishing"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Photobiomodulation, Photomedicine, and Laser Surgery","raw_type":"journal-article"},{"id":"pmid:37890115","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37890115","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Photobiomodulation, photomedicine, and laser surgery","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1846516945","https://openalex.org/W1976551431","https://openalex.org/W1986392685","https://openalex.org/W2021268953","https://openalex.org/W2033654371","https://openalex.org/W2070559585","https://openalex.org/W2080164497","https://openalex.org/W2089163839","https://openalex.org/W2111640373","https://openalex.org/W2112627566","https://openalex.org/W2126344303","https://openalex.org/W2145063848","https://openalex.org/W2154248482","https://openalex.org/W2218199574","https://openalex.org/W2301083995","https://openalex.org/W2337468716","https://openalex.org/W2566680017","https://openalex.org/W2582538848","https://openalex.org/W2586947273","https://openalex.org/W2618591258","https://openalex.org/W2883121408","https://openalex.org/W2948133828","https://openalex.org/W2957712509","https://openalex.org/W2980263197","https://openalex.org/W3087408425","https://openalex.org/W3186777719","https://openalex.org/W3217197348","https://openalex.org/W4220659174","https://openalex.org/W4221035558","https://openalex.org/W4284990457","https://openalex.org/W4288721981"],"related_works":["https://openalex.org/W4405492872","https://openalex.org/W3202387688","https://openalex.org/W4309711101","https://openalex.org/W2948133828","https://openalex.org/W4312891837","https://openalex.org/W3043374519","https://openalex.org/W4392755528","https://openalex.org/W4386320513","https://openalex.org/W3040604607","https://openalex.org/W2582538848"],"abstract_inverted_index":{"Background:Oral":[0],"mucositis":[1],"(OM)":[2],"is":[3,109,190],"a":[4,61,158,163],"common":[5],"adverse":[6],"effect":[7],"of":[8,27,54,123,137,160,165,172,192],"radiation":[9,48],"to":[10,45,95,132],"the":[11,25,52,134,170,177,185,194],"head":[12],"and":[13,84,99,115,120,142,162],"neck.":[14],"Recent":[15],"research":[16],"has":[17],"shown":[18],"that":[19,149,184],"extra":[20],"oral":[21],"photobiomodulation":[22,62],"(EO-PBM)":[23],"reduces":[24],"severity":[26,36,53],"OM.":[28],"However,":[29],"appropriate":[30],"EO-PBM":[31,47],"therapy":[32],"parameters":[33,49,196],"for":[34,50,113,198],"OM":[35,56],"reduction":[37],"have":[38],"not":[39],"been":[40],"documented.":[41],"Objective:This":[42],"work":[43],"aims":[44],"optimize":[46],"lowering":[51],"radiation-induced":[55],"in":[57],"rats":[58,77],"by":[59,127],"establishing":[60],"(PBM)":[63],"treatment":[64,144,187],"system":[65,189],"based":[66],"on":[67],"light-emitting":[68],"diode":[69],"arrays":[70],"with":[71,157,176],"top-hat":[72],"beam":[73],"profile.":[74],"Methods:The":[75],"36":[76],"are":[78,93],"separated":[79],"into":[80],"2":[81],"control":[82,140,179],"groups":[83,86,92,141],"4":[85,98],"receiving":[87],"PBM":[88,91,143,150,188],"treatment.":[89,200],"The":[90,105],"exposed":[94],"irradiance":[96],"between":[97,139],"24":[100],"J/cm2":[101,154],"at":[102,152],"660":[103],"nm.":[104],"cheek":[106],"pouch":[107],"mucosa":[108],"removed":[110],"after":[111],"scarification":[112],"biochemical":[114],"histological":[116],"examination.":[117],"Student's":[118],"t-test,":[119],"one-way":[121],"analysis":[122,147],"variance":[124],"(ANOVA)":[125],"followed":[126],"Tukey's":[128],"Multiple":[129],"were":[130],"applied":[131],"compare":[133],"statistical":[135],"significance":[136],"differences":[138],"groups.":[145],"Results:Statistical":[146],"reveals":[148],"irradiation":[151],"12":[153],"(200":[155],"sec)":[156],"flatness":[159],"0.8":[161],"diameter":[164],"3":[166],"cm":[167],"substantially":[168],"decreased":[169],"level":[171],"inflammatory":[173],"cytokines":[174],"compared":[175],"positive":[178],"group.":[180],"Conclusions:Our":[181],"results":[182],"indicate":[183],"designed":[186],"capable":[191],"delivering":[193],"optical":[195],"necessary":[197],"therapeutic":[199]},"counts_by_year":[{"year":2026,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-10-28T00:00:00"}