{"id":"https://openalex.org/W4387968339","doi":"https://doi.org/10.1055/s-0043-1771254","title":"Homoeopathic Pathogenetic Trial of Catharanthus roseus: A Multicentric, Double-Blind, Randomized, Placebo-Controlled Trial","display_name":"Homoeopathic Pathogenetic Trial of Catharanthus roseus: A Multicentric, Double-Blind, Randomized, Placebo-Controlled Trial","publication_year":2023,"publication_date":"2023-10-27","ids":{"openalex":"https://openalex.org/W4387968339","doi":"https://doi.org/10.1055/s-0043-1771254"},"language":"en","primary_location":{"id":"doi:10.1055/s-0043-1771254","doi":"https://doi.org/10.1055/s-0043-1771254","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0043-1771254","pdf_url":null,"source":{"id":"https://openalex.org/S149749991","display_name":"Hom\u0153opathic Links","issn_l":"1019-2050","issn":["1019-2050","1860-3149"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hom\u0153opathic Links","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091524307","display_name":"Pritha Mehra","orcid":"https://orcid.org/0000-0003-3551-5816","observed_orcids":["https://orcid.org/0000-0003-3551-5816"]},"institutions":[{"id":"https://openalex.org/I4210155405","display_name":"Central Council for Research in Homoeopathy","ror":"https://ror.org/04qawwn42","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I4210155405"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Pritha Mehra","raw_affiliation_strings":["Drug Proving Research, Central Council for Research in Homoeopathy, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Proving Research, Central Council for Research in Homoeopathy, New Delhi, India","institution_ids":["https://openalex.org/I4210155405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113031803","display_name":"Lipipushpa Debata","orcid":"https://orcid.org/0009-0000-1045-2113","observed_orcids":["https://orcid.org/0009-0000-1045-2113"]},"institutions":[{"id":"https://openalex.org/I4210155405","display_name":"Central Council for Research in Homoeopathy","ror":"https://ror.org/04qawwn42","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I4210155405"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Lipipushpa Debata","raw_affiliation_strings":["Homoeopathic Drug Research Institute, Lucknow under Central Council for Research in Homoeopathy, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Homoeopathic Drug Research Institute, Lucknow under Central Council for Research in Homoeopathy, New Delhi, India","institution_ids":["https://openalex.org/I4210155405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005822870","display_name":"Amulya Ratna Sahoo","orcid":"https://orcid.org/0000-0001-6755-409X","observed_orcids":["https://orcid.org/0000-0001-6755-409X"]},"institutions":[{"id":"https://openalex.org/I4210155405","display_name":"Central Council for Research in Homoeopathy","ror":"https://ror.org/04qawwn42","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I4210155405"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Amulya R. Sahoo","raw_affiliation_strings":["Drug Proving Unit, Bhubaneswar under Central Council for Research in Homoeopathy, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Drug Proving Unit, Bhubaneswar under Central Council for Research in Homoeopathy, New Delhi, India","institution_ids":["https://openalex.org/I4210155405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001569715","display_name":"B. S. J. Rajakumar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210155405","display_name":"Central Council for Research in Homoeopathy","ror":"https://ror.org/04qawwn42","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I4210155405"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"B. S. J. Rajakumar","raw_affiliation_strings":["Regional Research Institute of Homoeopathy, Gudivada under Central Council for Research in Homoeopathy, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Regional Research Institute of Homoeopathy, Gudivada under Central Council for Research in Homoeopathy, New Delhi, India","institution_ids":["https://openalex.org/I4210155405"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103904870","display_name":"Ashish Y. Mahajan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210155405","display_name":"Central Council for Research in Homoeopathy","ror":"https://ror.org/04qawwn42","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I4210155405"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Ashish Mahajan","raw_affiliation_strings":["Central Research Institute of Homoeopathy, Jaipur under Central Council for Research in Homoeopathy, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Central Research Institute of Homoeopathy, Jaipur under Central Council for Research in Homoeopathy, New Delhi, India","institution_ids":["https://openalex.org/I4210155405"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110613436","display_name":"B. S. Arya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210155405","display_name":"Central Council for Research in Homoeopathy","ror":"https://ror.org/04qawwn42","country_code":"IN","type":"government","lineage":["https://openalex.org/I2799351866","https://openalex.org/I4210148677","https://openalex.org/I4210155405"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Bhopal S. Arya","raw_affiliation_strings":["DDPR Central Research Institute of Homoeopathy, Noida under Central Council for Research in Homoeopathy, New Delhi, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DDPR Central Research Institute of Homoeopathy, Noida under Central Council for Research in Homoeopathy, New Delhi, India","institution_ids":["https://openalex.org/I4210155405"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210155405"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"36","issue":"04","first_page":"266","last_page":"280"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10902","display_name":"Complementary and Alternative Medicine Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10902","display_name":"Complementary and Alternative Medicine Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12657","display_name":"Phytochemistry Medicinal Plant Applications","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T14521","display_name":"Medicinal Plant Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/catharanthus-roseus","display_name":"Catharanthus roseus","score":1.0},{"id":"https://openalex.org/keywords/medicinal-plants","display_name":"medicinal plants","score":0.6859999895095825},{"id":"https://openalex.org/keywords/traditional-medicine","display_name":"traditional medicine","score":0.574999988079071},{"id":"https://openalex.org/keywords/symptom-elicitation","display_name":"symptom elicitation","score":0.5839999914169312}],"concepts":[{"id":"https://openalex.org/C2779906556","wikidata":"https://www.wikidata.org/wiki/Q161093","display_name":"Catharanthus roseus","level":2,"score":0.9666880965232849},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.8285079002380371},{"id":"https://openalex.org/C204243189","wikidata":"https://www.wikidata.org/wiki/Q1363085","display_name":"Randomization","level":3,"score":0.7353906035423279},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.5716073513031006},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5043188333511353},{"id":"https://openalex.org/C176762198","wikidata":"https://www.wikidata.org/wiki/Q81058","display_name":"Homeopathy","level":3,"score":0.46341222524642944},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.45860040187835693},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.4134269654750824},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.28572899103164673},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2616581916809082},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.2012852430343628},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1855437457561493},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.14744186401367188}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1055/s-0043-1771254","doi":"https://doi.org/10.1055/s-0043-1771254","is_oa":false,"landing_page_url":"https://doi.org/10.1055/s-0043-1771254","pdf_url":null,"source":{"id":"https://openalex.org/S149749991","display_name":"Hom\u0153opathic Links","issn_l":"1019-2050","issn":["1019-2050","1860-3149"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310321135","host_organization_name":"Georg Thieme Verlag","host_organization_lineage":["https://openalex.org/P4310321135","https://openalex.org/P4310320000"],"host_organization_lineage_names":["Georg Thieme Verlag","Thieme Medical Publishers (Germany)"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Hom\u0153opathic Links","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W2040118142","https://openalex.org/W2044727962","https://openalex.org/W2050247711","https://openalex.org/W2108696783","https://openalex.org/W2111912498","https://openalex.org/W2156536935","https://openalex.org/W2191647228","https://openalex.org/W2331106078","https://openalex.org/W2491275841","https://openalex.org/W2606826291","https://openalex.org/W2738249427","https://openalex.org/W3082991524","https://openalex.org/W3109818021","https://openalex.org/W3189734996","https://openalex.org/W4318336136","https://openalex.org/W6799569994"],"related_works":["https://openalex.org/W3185204271","https://openalex.org/W2924423169","https://openalex.org/W2307500324","https://openalex.org/W2744153300","https://openalex.org/W2995201860","https://openalex.org/W2932588604","https://openalex.org/W2185160704","https://openalex.org/W2009787061","https://openalex.org/W2992504010","https://openalex.org/W2623342578"],"abstract_inverted_index":{"Abstract":[0],"Medicinal":[1],"plants":[2],"have":[3,215],"a":[4,39,58,245],"long":[5],"history":[6],"of":[7,48,119,132,147,180,187,232,235],"usage":[8],"in":[9,51,75,90,98,106,113,126,144,209,219],"traditional":[10],"medicine,":[11],"and":[12,110,152,169,197,238],"Catharanthus":[13],"roseus":[14,50,105,237],"L.":[15],"(G.)":[16],"Don":[17],"is":[18],"one":[19],"such":[20],"plant.":[21],"However,":[22],"to":[23,32,240],"understand":[24],"its":[25],"homoeopathic":[26,52],"therapeutic":[27],"effect,":[28],"it":[29],"was":[30,64],"important":[31],"find":[33],"the":[34,45,70,91,99,128,148,156,162,166,170,176,181,184,188,210,230,233],"pathogenetic":[35,46,196,223],"powers":[36],"by":[37,161,165,206,244],"conducting":[38],"drug":[40],"proving":[41,78,167],"trial.":[42,149],"To":[43],"elicit":[44],"response":[47,224],"C.":[49,104,236],"potencies":[53,112],"on":[54],"healthy":[55,83],"human":[56],"provers,":[57,163],"multicenter,":[59],"randomized,":[60],"double-blind,":[61],"placebo-controlled":[62],"trial":[63,79,157,228],"conducted":[65],"at":[66,175],"four":[67,114],"centers":[68],"under":[69],"Central":[71],"Council":[72],"for":[73,139],"Research":[74],"Homoeopathy.":[76],"The":[77,116,150,213,222],"involved":[80],"60":[81],"relatively":[82],"provers.":[84],"All":[85],"provers":[86,97,121,186,193,208],"were":[87,102,122,142,158,172,204],"given":[88,103],"placebo":[89,199],"first":[92],"phase.":[93],"After":[94],"randomization,":[95],"40":[96,185],"intervention":[100],"group":[101,118],"6C,":[107],"12C,":[108],"30C,":[109],"200C":[111,220],"phases.":[115,129],"control":[117,211],"20":[120],"administered":[123,143],"unmedicated":[124],"globules":[125],"all":[127,145],"A":[130],"maximum":[131],"12":[133,207],"doses":[134],"divided":[135],"into":[136],"4":[137],"doses/day":[138],"3":[140],"days":[141],"phases":[146],"symptoms":[151,203,214],"signs":[153],"manifested":[154,194,217],"during":[155,226],"noted":[159],"down":[160],"elaborated":[164],"masters,":[168],"data":[171],"finally":[173],"processed":[174],"proving-cum-data":[177],"processing":[178],"cell":[179],"Council.":[182],"Among":[183],"verum":[189],"group,":[190],"only":[191],"15":[192],"22":[195],"10":[198],"symptoms,":[200],"whereas":[201],"30":[202],"reported":[205],"group.":[212],"been":[216],"predominantly":[218],"potency.":[221],"elicited":[225],"this":[227],"expands":[229],"scope":[231],"use":[234],"needs":[239],"be":[241],"further":[242],"validated":[243],"clinical":[246],"verification":[247],"study.":[248]},"counts_by_year":[],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2023-10-28T00:00:00"}
