{"id":"https://openalex.org/W4387965416","doi":"https://doi.org/10.2174/0109298673266304231015070956","title":"Marine Fungi: A Prosperous Source of Novel Bioactive Natural Products","display_name":"Marine Fungi: A Prosperous Source of Novel Bioactive Natural Products","publication_year":2023,"publication_date":"2023-10-27","ids":{"openalex":"https://openalex.org/W4387965416","doi":"https://doi.org/10.2174/0109298673266304231015070956","pmid":"https://pubmed.ncbi.nlm.nih.gov/37885109"},"language":"en","primary_location":{"id":"doi:10.2174/0109298673266304231015070956","doi":"https://doi.org/10.2174/0109298673266304231015070956","is_oa":false,"landing_page_url":"https://doi.org/10.2174/0109298673266304231015070956","pdf_url":null,"source":{"id":"https://openalex.org/S33159018","display_name":"Current Medicinal Chemistry","issn_l":"0929-8673","issn":["0929-8673","1875-533X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Medicinal Chemistry","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100933247","display_name":"Rong Ji","orcid":"https://orcid.org/0009-0001-7813-8144","observed_orcids":["https://orcid.org/0009-0001-7813-8144"]},"institutions":[{"id":"https://openalex.org/I79731167","display_name":"Hainan Medical University","ror":"https://ror.org/004eeze55","country_code":"CN","type":"education","lineage":["https://openalex.org/I79731167"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Rong Ji","raw_affiliation_strings":["Key Laboratory of Tropical Translational Medicine of Ministry of Education, Key Laboratory of Tropical\nMolecular Pharmacology and Advanced Diagnostic Technology, School of Tropical Medicine, Hainan Medical\nUniversity, Haikou, Hainan, 571199, China","Key Laboratory of Tropical Translational Medicine of Ministry of Education, NHC Key Laboratory of Control of Tropical Disease Control, Key Laboratory of Tropical Molecular Pharmacology and Advanced Diagnostic Technology, School of Tropical Medicine, Hainan Medical University, Haikou, Hainan, 571199,\nChina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Tropical Translational Medicine of Ministry of Education, Key Laboratory of Tropical\nMolecular Pharmacology and Advanced Diagnostic Technology, School of Tropical Medicine, Hainan Medical\nUniversity, Haikou, Hainan, 571199, China","institution_ids":["https://openalex.org/I79731167"]},{"raw_affiliation_string":"Key Laboratory of Tropical Translational Medicine of Ministry of Education, NHC Key Laboratory of Control of Tropical Disease Control, Key Laboratory of Tropical Molecular Pharmacology and Advanced Diagnostic Technology, School of Tropical Medicine, Hainan Medical University, Haikou, Hainan, 571199,\nChina","institution_ids":["https://openalex.org/I79731167"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017148623","display_name":"Xiangru Zha","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79731167","display_name":"Hainan Medical University","ror":"https://ror.org/004eeze55","country_code":"CN","type":"education","lineage":["https://openalex.org/I79731167"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiangru Zha","raw_affiliation_strings":["Key Laboratory of Tropical Translational Medicine of Ministry of Education, Key Laboratory of Tropical\nMolecular Pharmacology and Advanced Diagnostic Technology, School of Tropical Medicine, Hainan Medical\nUniversity, Haikou, Hainan, 571199, China","Key Laboratory of Tropical Translational Medicine of Ministry of Education, NHC Key Laboratory of Control of Tropical Disease Control, Key Laboratory of Tropical Molecular Pharmacology and Advanced Diagnostic Technology, School of Tropical Medicine, Hainan Medical University, Haikou, Hainan, 571199,\nChina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Tropical Translational Medicine of Ministry of Education, Key Laboratory of Tropical\nMolecular Pharmacology and Advanced Diagnostic Technology, School of Tropical Medicine, Hainan Medical\nUniversity, Haikou, Hainan, 571199, China","institution_ids":["https://openalex.org/I79731167"]},{"raw_affiliation_string":"Key Laboratory of Tropical Translational Medicine of Ministry of Education, NHC Key Laboratory of Control of Tropical Disease Control, Key Laboratory of Tropical Molecular Pharmacology and Advanced Diagnostic Technology, School of Tropical Medicine, Hainan Medical University, Haikou, Hainan, 571199,\nChina","institution_ids":["https://openalex.org/I79731167"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057967562","display_name":"Songlin Zhou","orcid":"https://orcid.org/0000-0001-8598-0922","observed_orcids":["https://orcid.org/0000-0001-8598-0922"]},"institutions":[{"id":"https://openalex.org/I79731167","display_name":"Hainan Medical University","ror":"https://ror.org/004eeze55","country_code":"CN","type":"education","lineage":["https://openalex.org/I79731167"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Songlin Zhou","raw_affiliation_strings":["Key Laboratory of Tropical Translational Medicine of Ministry of Education, Key Laboratory of Tropical\nMolecular Pharmacology and Advanced Diagnostic Technology, School of Tropical Medicine, Hainan Medical\nUniversity, Haikou, Hainan, 571199, China","Key Laboratory of Tropical Translational Medicine of Ministry of Education, NHC Key Laboratory of Control of Tropical Disease Control, Key Laboratory of Tropical Molecular Pharmacology and Advanced Diagnostic Technology, School of Tropical Medicine, Hainan Medical University, Haikou, Hainan, 571199,\nChina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Key Laboratory of Tropical Translational Medicine of Ministry of Education, Key Laboratory of Tropical\nMolecular Pharmacology and Advanced Diagnostic Technology, School of Tropical Medicine, Hainan Medical\nUniversity, Haikou, Hainan, 571199, China","institution_ids":["https://openalex.org/I79731167"]},{"raw_affiliation_string":"Key Laboratory of Tropical Translational Medicine of Ministry of Education, NHC Key Laboratory of Control of Tropical Disease Control, Key Laboratory of Tropical Molecular Pharmacology and Advanced Diagnostic Technology, School of Tropical Medicine, Hainan Medical University, Haikou, Hainan, 571199,\nChina","institution_ids":["https://openalex.org/I79731167"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5057967562"],"corresponding_institution_ids":["https://openalex.org/I79731167"],"apc_list":null,"apc_paid":null,"fwci":0.4365,"has_fulltext":false,"cited_by_count":18,"citation_normalized_percentile":{"value":0.36666667,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"32","issue":"5","first_page":"992","last_page":"1006"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9253000020980835,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis","score":0.9253000020980835,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11340","display_name":"Marine Sponges and Natural Products","score":0.07370000332593918,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11390","display_name":"Seaweed-derived Bioactive Compounds","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/marine-fungi","display_name":"marine fungi","score":1.0},{"id":"https://openalex.org/keywords/fungal-natural-products","display_name":"fungal natural products","score":0.7900000214576721},{"id":"https://openalex.org/keywords/bioactive-compounds","display_name":"bioactive compounds","score":0.8519999980926514},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"drug discovery","score":0.6349999904632568},{"id":"https://openalex.org/keywords/secondary-metabolism","display_name":"secondary metabolism","score":0.6380000114440918},{"id":"https://openalex.org/keywords/alkaloids","display_name":"alkaloids","score":0.699999988079071},{"id":"https://openalex.org/keywords/terpenoids","display_name":"terpenoids","score":1.0},{"id":"https://openalex.org/keywords/anthraquinones","display_name":"anthraquinones","score":0.9869999885559082},{"id":"https://openalex.org/keywords/polyketones","display_name":"polyketones","score":0.8759999871253967},{"id":"https://openalex.org/keywords/antiviral-activity","display_name":"antiviral activity","score":0.9660000205039978},{"id":"https://openalex.org/keywords/anticancer-activity","display_name":"anticancer activity","score":0.9819999933242798},{"id":"https://openalex.org/keywords/antibacterial-activity","display_name":"antibacterial activity","score":0.9990000128746033},{"id":"https://openalex.org/keywords/anti-inflammatory-activity","display_name":"anti-inflammatory activity","score":0.9929999709129333},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.5170000195503235},{"id":"https://openalex.org/keywords/research-trends","display_name":"research trends","score":0.5870000123977661}],"concepts":[{"id":"https://openalex.org/C196405362","wikidata":"https://www.wikidata.org/wiki/Q6764285","display_name":"Marine fungi","level":2,"score":0.6627062559127808},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4650994539260864},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.4447406828403473},{"id":"https://openalex.org/C130217890","wikidata":"https://www.wikidata.org/wiki/Q47041","display_name":"Biodiversity","level":2,"score":0.423470139503479},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3805997669696808},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.24704104661941528},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.1849478781223297}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001688","descriptor_name":"Biological Products","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D001688","descriptor_name":"Biological Products","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001688","descriptor_name":"Biological Products","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005658","descriptor_name":"Fungi","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059001","descriptor_name":"Aquatic Organisms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.2174/0109298673266304231015070956","doi":"https://doi.org/10.2174/0109298673266304231015070956","is_oa":false,"landing_page_url":"https://doi.org/10.2174/0109298673266304231015070956","pdf_url":null,"source":{"id":"https://openalex.org/S33159018","display_name":"Current Medicinal Chemistry","issn_l":"0929-8673","issn":["0929-8673","1875-533X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Medicinal Chemistry","raw_type":"journal-article"},{"id":"pmid:37885109","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37885109","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current medicinal chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1250140156","display_name":null,"funder_award_id":"ZDYF2023SHFZ114","funder_id":"https://openalex.org/F4320327827","funder_display_name":"Key Research and Development Project of Hainan Province"},{"id":"https://openalex.org/G7917381936","display_name":"\u7eff\u8272\u5408\u6210\u7684\u85ff\u9999\u84df\u7eb3\u7c73\u94f6\u6b62\u8840\u4f5c\u7528\u53ca\u673a\u5236\u7684\u7814\u7a76","funder_award_id":"522RC684","funder_id":"https://openalex.org/F4320322866","funder_display_name":"Natural Science Foundation of Hainan Province"}],"funders":[{"id":"https://openalex.org/F4320322866","display_name":"Natural Science Foundation of Hainan Province","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320327827","display_name":"Key Research and Development Project of Hainan Province","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W2093427616","https://openalex.org/W2168972008","https://openalex.org/W2338138720","https://openalex.org/W2397385657","https://openalex.org/W2550338717","https://openalex.org/W2624189777","https://openalex.org/W2768085946","https://openalex.org/W2770928629","https://openalex.org/W2789056813","https://openalex.org/W2804339030","https://openalex.org/W2881450897","https://openalex.org/W2883386609","https://openalex.org/W2886953951","https://openalex.org/W2890742015","https://openalex.org/W2893775482","https://openalex.org/W2899475919","https://openalex.org/W2910816174","https://openalex.org/W2921935994","https://openalex.org/W2938686566","https://openalex.org/W2939745837","https://openalex.org/W2963979140","https://openalex.org/W2966093529","https://openalex.org/W2968847299","https://openalex.org/W2969876208","https://openalex.org/W2975749334","https://openalex.org/W2976781115","https://openalex.org/W2977969423","https://openalex.org/W2986669405","https://openalex.org/W2987509256","https://openalex.org/W2989306344","https://openalex.org/W2990295208","https://openalex.org/W2990613596","https://openalex.org/W2996238309","https://openalex.org/W3006667348","https://openalex.org/W3014246414","https://openalex.org/W3017253017","https://openalex.org/W3018701554","https://openalex.org/W3035835645","https://openalex.org/W3045018055","https://openalex.org/W3047881025","https://openalex.org/W3080548634","https://openalex.org/W3080857872","https://openalex.org/W3086135887","https://openalex.org/W3091305260","https://openalex.org/W3102029978","https://openalex.org/W3113232131","https://openalex.org/W3113836148","https://openalex.org/W3120053497","https://openalex.org/W3122040976","https://openalex.org/W3124141894","https://openalex.org/W3130476753","https://openalex.org/W3133764988","https://openalex.org/W3140916200","https://openalex.org/W3160267742","https://openalex.org/W3186876948","https://openalex.org/W3196409840","https://openalex.org/W3203433659","https://openalex.org/W3210369405","https://openalex.org/W4200033896","https://openalex.org/W4200427369","https://openalex.org/W4205837347","https://openalex.org/W4210655964","https://openalex.org/W4214501066","https://openalex.org/W4220845441","https://openalex.org/W4287832818","https://openalex.org/W4288720753","https://openalex.org/W4297537786","https://openalex.org/W4306736975","https://openalex.org/W4310214175","https://openalex.org/W4320709510","https://openalex.org/W4323852759","https://openalex.org/W4377140300","https://openalex.org/W4377968938","https://openalex.org/W4382364330"],"related_works":["https://openalex.org/W3179535110","https://openalex.org/W2338138720","https://openalex.org/W3080827113","https://openalex.org/W2360274595","https://openalex.org/W2471862612","https://openalex.org/W3107845475","https://openalex.org/W2035158433","https://openalex.org/W4392250455","https://openalex.org/W4310256162","https://openalex.org/W2170059001"],"abstract_inverted_index":{"As":[0],"the":[1,58,68,72,88,105,143,157],"number":[2],"of":[3,61,81,96,147,159,165],"viruses,":[4],"bacteria,":[5],"and":[6,37,74,91,137,145,162,169,184],"tumors":[7],"that":[8],"are":[9],"resistant":[10],"to":[11,14,25,31,56,113],"drugs":[12,180],"continues":[13],"rise,":[15],"there":[16],"is":[17],"a":[18,42],"growing":[19],"need":[20],"for":[21,45,174],"novel":[22,97,110],"lead":[23,46],"compounds":[24,47,99,111],"treat":[26],"them.":[27],"Marine":[28],"fungi,":[29],"due":[30],"their":[32,166],"unique":[33],"secondary":[34],"metabolic":[35],"pathways":[36],"vast":[38],"biodiversity,":[39],"have":[40],"become":[41],"crucial":[43],"source":[44],"in":[48,67,76,104,151,177],"drug":[49],"development.":[50],"This":[51,140],"review":[52,86,141],"utilizes":[53],"bibliometric":[54],"methods":[55],"analyze":[57],"research":[59,150],"status":[60],"natural":[62,98,167],"products":[63],"from":[64,79,101,181],"marine":[65,102,148,182],"fungi":[66,103,149,183],"past":[69,106],"decade,":[70],"revealing":[71],"hotspots":[73,144],"trends":[75,146],"this":[77,85],"field":[78],"Web":[80],"Science":[82],"database.":[83],"Furthermore,":[84],"summarizes":[87],"biological":[89,130,163],"activities":[90,164],"effects":[92],"on":[93],"molecular":[94],"mechanisms":[95],"isolated":[100],"five":[107],"years.":[108],"These":[109],"belong":[112],"six":[114],"different":[115],"structural":[116],"classes,":[117],"such":[118],"as":[119,154,156],"alkaloids,":[120],"terpenoids,":[121],"anthraquinones,":[122],"polyketones,":[123],"etc.":[124],"They":[125],"also":[126],"exhibited":[127],"highly":[128],"potent":[129],"properties,":[131],"including":[132],"antiviral,":[133],"antitumor,":[134],"antibacterial,":[135],"antiinflammatory,":[136],"other":[138],"properties.":[139],"demonstrates":[142],"recent":[152],"years,":[153],"well":[155],"variety":[158],"chemical":[160],"structure":[161],"products,":[168],"it":[170],"may":[171],"provide":[172],"guidance":[173],"those":[175],"interested":[176],"discovering":[178],"new":[179],"specific":[185],"targeting":[186],"mechanisms.":[187]},"counts_by_year":[{"year":2026,"cited_by_count":11},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2023-10-28T00:00:00"}