{"id":"https://openalex.org/W4387965110","doi":"https://doi.org/10.1038/s41589-023-01452-w","title":"Mitochondrial matrix RTN4IP1/OPA10 is an oxidoreductase for coenzyme Q synthesis","display_name":"Mitochondrial matrix RTN4IP1/OPA10 is an oxidoreductase for coenzyme Q synthesis","publication_year":2023,"publication_date":"2023-10-26","ids":{"openalex":"https://openalex.org/W4387965110","doi":"https://doi.org/10.1038/s41589-023-01452-w","pmid":"https://pubmed.ncbi.nlm.nih.gov/37884807","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10830421"},"language":"en","primary_location":{"id":"doi:10.1038/s41589-023-01452-w","doi":"https://doi.org/10.1038/s41589-023-01452-w","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41589-023-01452-w","pdf_url":"https://www.nature.com/articles/s41589-023-01452-w.pdf","source":{"id":"https://openalex.org/S51309854","display_name":"Nature Chemical Biology","issn_l":"1552-4450","issn":["1552-4450","1552-4469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Chemical Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.nature.com/articles/s41589-023-01452-w.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Isaac Park","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Isaac Park","raw_affiliation_strings":["Department of Chemistry, Seoul National University, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071104452","display_name":"Kwang-eun Kim","orcid":"https://orcid.org/0000-0002-5355-1979","observed_orcids":["https://orcid.org/0000-0002-5355-1979"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I157485424","display_name":"Korea Advanced Institute of Science and Technology","ror":"https://ror.org/05apxxy63","country_code":"KR","type":"education","lineage":["https://openalex.org/I157485424"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kwang-eun Kim","raw_affiliation_strings":["Department of Chemistry, Seoul National University, Seoul, Republic of Korea","Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-5355-1979","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea","institution_ids":["https://openalex.org/I157485424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049434005","display_name":"Jeesoo Kim","orcid":"https://orcid.org/0000-0001-5299-5765","observed_orcids":["https://orcid.org/0000-0001-5299-5765"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I4210104335","display_name":"Institute for Basic Science","ror":"https://ror.org/00y0zf565","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210104335"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jeesoo Kim","raw_affiliation_strings":["Center for RNA Research, Institute for Basic Science, Seoul, Republic of Korea","Center for RNA Research, Institute for Basic Science, Seoul, Republic of Korea. jongseokim@snu.ac.kr","School of Biological Sciences, Seoul National University, Seoul, Republic of Korea","School of Biological Sciences, Seoul National University, Seoul, Republic of Korea. jongseokim@snu.ac.kr"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for RNA Research, Institute for Basic Science, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I4210104335"]},{"raw_affiliation_string":"Center for RNA Research, Institute for Basic Science, Seoul, Republic of Korea. jongseokim@snu.ac.kr","institution_ids":["https://openalex.org/I139264467","https://openalex.org/I4210104335"]},{"raw_affiliation_string":"School of Biological Sciences, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"School of Biological Sciences, Seoul National University, Seoul, Republic of Korea. jongseokim@snu.ac.kr","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ae-Kyeong Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I73616290","display_name":"Korea Research Institute of Bioscience and Biotechnology","ror":"https://ror.org/03ep23f07","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210144908","https://openalex.org/I4387152098","https://openalex.org/I73616290"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ae-Kyeong Kim","raw_affiliation_strings":["Metabolism and Neurophysiology Research Group, KRIBB, Daejeon, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Metabolism and Neurophysiology Research Group, KRIBB, Daejeon, Republic of Korea","institution_ids":["https://openalex.org/I73616290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008578682","display_name":"Subin Bae","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I31419693","display_name":"Kyungpook National University","ror":"https://ror.org/040c17130","country_code":"KR","type":"education","lineage":["https://openalex.org/I31419693"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Subin Bae","raw_affiliation_strings":["BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, Korea","institution_ids":["https://openalex.org/I31419693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109616230","display_name":"Minkyo Jung","orcid":"https://orcid.org/0000-0002-3288-3288","observed_orcids":["https://orcid.org/0000-0002-3288-3288"]},"institutions":[{"id":"https://openalex.org/I4210155455","display_name":"Korea Brain Research Institute","ror":"https://ror.org/055zd7d59","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210155455"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Minkyo Jung","raw_affiliation_strings":["Neural Circuit Research Group, Korea Brain Research Institute, Daegu, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neural Circuit Research Group, Korea Brain Research Institute, Daegu, Republic of Korea","institution_ids":["https://openalex.org/I4210155455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079490800","display_name":"Jinhyuk Choi","orcid":"https://orcid.org/0000-0002-0316-5973","observed_orcids":["https://orcid.org/0000-0002-0316-5973"]},"institutions":[{"id":"https://openalex.org/I157485424","display_name":"Korea Advanced Institute of Science and Technology","ror":"https://ror.org/05apxxy63","country_code":"KR","type":"education","lineage":["https://openalex.org/I157485424"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jinhyuk Choi","raw_affiliation_strings":["Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea","institution_ids":["https://openalex.org/I157485424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012763936","display_name":"Pratyush Kumar Mishra","orcid":"https://orcid.org/0000-0002-7202-5093","observed_orcids":["https://orcid.org/0000-0002-7202-5093"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Pratyush Kumar Mishra","raw_affiliation_strings":["Department of Chemistry, Seoul National University, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-7202-5093","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058274925","display_name":"Taek-Min Kim","orcid":"https://orcid.org/0009-0002-0481-7213","observed_orcids":["https://orcid.org/0009-0002-0481-7213"]},"institutions":[{"id":"https://openalex.org/I157485424","display_name":"Korea Advanced Institute of Science and Technology","ror":"https://ror.org/05apxxy63","country_code":"KR","type":"education","lineage":["https://openalex.org/I157485424"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Taek-Min Kim","raw_affiliation_strings":["Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea","institution_ids":["https://openalex.org/I157485424"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049345951","display_name":"Chulhwan S. Kwak","orcid":"https://orcid.org/0000-0003-0041-2681","observed_orcids":["https://orcid.org/0000-0003-0041-2681"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Chulhwan Kwak","raw_affiliation_strings":["Department of Chemistry, Seoul National University, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102495687","display_name":"Myeong\u2010Gyun Kang","orcid":"https://orcid.org/0009-0006-4395-1537","observed_orcids":["https://orcid.org/0009-0006-4395-1537"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Myeong-Gyun Kang","raw_affiliation_strings":["Department of Chemistry, Seoul National University, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000327490","display_name":"Chang\u2010Mo Yoo","orcid":"https://orcid.org/0000-0001-9370-2789","observed_orcids":["https://orcid.org/0000-0001-9370-2789"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Chang-Mo Yoo","raw_affiliation_strings":["Department of Chemistry, Seoul National University, Seoul, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001441680","display_name":"Ji Young Mun","orcid":"https://orcid.org/0000-0003-0820-6233","observed_orcids":["https://orcid.org/0000-0003-0820-6233"]},"institutions":[{"id":"https://openalex.org/I4210155455","display_name":"Korea Brain Research Institute","ror":"https://ror.org/055zd7d59","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210155455"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Ji Young Mun","raw_affiliation_strings":["Neural Circuit Research Group, Korea Brain Research Institute, Daegu, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neural Circuit Research Group, Korea Brain Research Institute, Daegu, Republic of Korea","institution_ids":["https://openalex.org/I4210155455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058455540","display_name":"Kyu\u2010Sun Lee","orcid":"https://orcid.org/0000-0002-4529-5186","observed_orcids":["https://orcid.org/0000-0002-4529-5186"]},"institutions":[{"id":"https://openalex.org/I31419693","display_name":"Kyungpook National University","ror":"https://ror.org/040c17130","country_code":"KR","type":"education","lineage":["https://openalex.org/I31419693"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Kwang-Hyeon Liu","raw_affiliation_strings":["BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy and Research Institute of Pharmaceutical Sciences, Kyungpook National University, Daegu, Korea","institution_ids":["https://openalex.org/I31419693"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108092653","display_name":"Kyu\u2010Sun Lee","orcid":"https://orcid.org/0000-0002-4529-5186","observed_orcids":["https://orcid.org/0000-0002-4529-5186"]},"institutions":[{"id":"https://openalex.org/I73616290","display_name":"Korea Research Institute of Bioscience and Biotechnology","ror":"https://ror.org/03ep23f07","country_code":"KR","type":"facility","lineage":["https://openalex.org/I2801339556","https://openalex.org/I4210144908","https://openalex.org/I4387152098","https://openalex.org/I73616290"]},{"id":"https://openalex.org/I848706","display_name":"Sungkyunkwan University","ror":"https://ror.org/04q78tk20","country_code":"KR","type":"education","lineage":["https://openalex.org/I848706"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Kyu-Sun Lee","raw_affiliation_strings":["Metabolism and Neurophysiology Research Group, KRIBB, Daejeon, Republic of Korea. ekuse74@kribb.re.kr","School of Pharmacy, Sungkyunkwan University, Suwon, Korea. ekuse74@kribb.re.kr","Metabolism and Neurophysiology Research Group, KRIBB, Daejeon, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-4529-5186","affiliations":[{"raw_affiliation_string":"Metabolism and Neurophysiology Research Group, KRIBB, Daejeon, Republic of Korea. ekuse74@kribb.re.kr","institution_ids":["https://openalex.org/I73616290"]},{"raw_affiliation_string":"School of Pharmacy, Sungkyunkwan University, Suwon, Korea. ekuse74@kribb.re.kr","institution_ids":["https://openalex.org/I848706"]},{"raw_affiliation_string":"Metabolism and Neurophysiology Research Group, KRIBB, Daejeon, Republic of Korea","institution_ids":["https://openalex.org/I73616290"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jong-Seo Kim","orcid":"https://orcid.org/0000-0002-8909-8440","observed_orcids":["https://orcid.org/0000-0002-8909-8440"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]},{"id":"https://openalex.org/I4210104335","display_name":"Institute for Basic Science","ror":"https://ror.org/00y0zf565","country_code":"KR","type":"facility","lineage":["https://openalex.org/I4210104335"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jong-Seo Kim","raw_affiliation_strings":["Center for RNA Research, Institute for Basic Science, Seoul, Republic of Korea","Center for RNA Research, Institute for Basic Science, Seoul, Republic of Korea. jongseokim@snu.ac.kr","School of Biological Sciences, Seoul National University, Seoul, Republic of Korea","School of Biological Sciences, Seoul National University, Seoul, Republic of Korea. jongseokim@snu.ac.kr"],"raw_orcid":"https://orcid.org/0000-0002-8909-8440","affiliations":[{"raw_affiliation_string":"Center for RNA Research, Institute for Basic Science, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I4210104335"]},{"raw_affiliation_string":"Center for RNA Research, Institute for Basic Science, Seoul, Republic of Korea. jongseokim@snu.ac.kr","institution_ids":["https://openalex.org/I139264467","https://openalex.org/I4210104335"]},{"raw_affiliation_string":"School of Biological Sciences, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"School of Biological Sciences, Seoul National University, Seoul, Republic of Korea. jongseokim@snu.ac.kr","institution_ids":["https://openalex.org/I139264467"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073934092","display_name":"Jae Myoung Suh","orcid":"https://orcid.org/0000-0001-8097-4662","observed_orcids":["https://orcid.org/0000-0001-8097-4662"]},"institutions":[{"id":"https://openalex.org/I157485424","display_name":"Korea Advanced Institute of Science and Technology","ror":"https://ror.org/05apxxy63","country_code":"KR","type":"education","lineage":["https://openalex.org/I157485424"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jae Myoung Suh","raw_affiliation_strings":["Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea. jmsuh@kaist.ac.kr","Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0001-8097-4662","affiliations":[{"raw_affiliation_string":"Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea. jmsuh@kaist.ac.kr","institution_ids":["https://openalex.org/I157485424"]},{"raw_affiliation_string":"Graduate School of Medical Science and Engineering, KAIST, Daejeon, Republic of Korea","institution_ids":["https://openalex.org/I157485424"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049147819","display_name":"Hyun\u2010Woo Rhee","orcid":"https://orcid.org/0000-0002-3817-3455","observed_orcids":["https://orcid.org/0000-0002-3817-3455"]},"institutions":[{"id":"https://openalex.org/I139264467","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542","country_code":"KR","type":"education","lineage":["https://openalex.org/I139264467"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Hyun-Woo Rhee","raw_affiliation_strings":["Department of Chemistry, Seoul National University, Seoul, Republic of Korea. rheehw@snu.ac.kr","School of Biological Sciences, Seoul National University, Seoul, Republic of Korea. rheehw@snu.ac.kr","School of Biological Sciences, Seoul National University, Seoul, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-3817-3455","affiliations":[{"raw_affiliation_string":"Department of Chemistry, Seoul National University, Seoul, Republic of Korea. rheehw@snu.ac.kr","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"School of Biological Sciences, Seoul National University, Seoul, Republic of Korea. rheehw@snu.ac.kr","institution_ids":["https://openalex.org/I139264467"]},{"raw_affiliation_string":"School of Biological Sciences, Seoul National University, Seoul, Republic of Korea","institution_ids":["https://openalex.org/I139264467"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5049147819","https://openalex.org/A5049434005","https://openalex.org/A5073934092","https://openalex.org/A5108092653"],"corresponding_institution_ids":["https://openalex.org/I139264467","https://openalex.org/I157485424","https://openalex.org/I4210104335","https://openalex.org/I73616290","https://openalex.org/I848706"],"apc_list":{"value":11690,"currency":"USD","value_usd":11690},"apc_paid":{"value":11690,"currency":"USD","value_usd":11690},"fwci":2.8578,"has_fulltext":true,"cited_by_count":40,"citation_normalized_percentile":{"value":0.93165856,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":100},"biblio":{"volume":"20","issue":"2","first_page":"221","last_page":"233"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13012","display_name":"Coenzyme Q10 studies and effects","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13012","display_name":"Coenzyme Q10 studies and effects","score":0.989300012588501,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology","score":0.00800000037997961,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13127","display_name":"Biotin and Related Studies","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coenzyme-q-biosynthesis","display_name":"coenzyme Q biosynthesis","score":0.9800000190734863},{"id":"https://openalex.org/keywords/mitochondrial-matrix","display_name":"mitochondrial matrix","score":0.6179999709129333},{"id":"https://openalex.org/keywords/nadph-oxidoreductase","display_name":"NADPH oxidoreductase","score":0.9559999704360962},{"id":"https://openalex.org/keywords/ascorbate-peroxidase","display_name":"ascorbate peroxidase","score":0.8700000047683716},{"id":"https://openalex.org/keywords/muscle-respiration","display_name":"muscle respiration","score":0.7049999833106995}],"concepts":[{"id":"https://openalex.org/C2779268744","wikidata":"https://www.wikidata.org/wiki/Q407479","display_name":"Oxidoreductase","level":3,"score":0.7123537063598633},{"id":"https://openalex.org/C11701378","wikidata":"https://www.wikidata.org/wiki/Q3493378","display_name":"Mitochondrial matrix","level":4,"score":0.694472074508667},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.621039628982544},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5609383583068848},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.5608989000320435},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.4928922653198242},{"id":"https://openalex.org/C9760119","wikidata":"https://www.wikidata.org/wiki/Q841382","display_name":"Interactome","level":3,"score":0.4829210937023163},{"id":"https://openalex.org/C14471203","wikidata":"https://www.wikidata.org/wiki/Q412832","display_name":"Coenzyme Q \u2013 cytochrome c reductase","level":4,"score":0.4565652310848236},{"id":"https://openalex.org/C75520062","wikidata":"https://www.wikidata.org/wiki/Q15321392","display_name":"NAD+ kinase","level":3,"score":0.4216141700744629},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3915681838989258},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3413447141647339},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.33564019203186035},{"id":"https://openalex.org/C98539663","wikidata":"https://www.wikidata.org/wiki/Q220599","display_name":"Cytosol","level":3,"score":0.20174440741539001},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11890745162963867},{"id":"https://openalex.org/C29311851","wikidata":"https://www.wikidata.org/wiki/Q408223","display_name":"Cytochrome c","level":3,"score":0.11340746283531189}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004331","descriptor_name":"Drosophila melanogaster","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D010088","descriptor_name":"Oxidoreductases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014451","descriptor_name":"Ubiquinone","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020543","descriptor_name":"Proteome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024101","descriptor_name":"Mitochondrial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/s41589-023-01452-w","doi":"https://doi.org/10.1038/s41589-023-01452-w","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41589-023-01452-w","pdf_url":"https://www.nature.com/articles/s41589-023-01452-w.pdf","source":{"id":"https://openalex.org/S51309854","display_name":"Nature Chemical Biology","issn_l":"1552-4450","issn":["1552-4450","1552-4469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Chemical Biology","raw_type":"journal-article"},{"id":"doi:10.1101/2021.10.14.464368","doi":"https://doi.org/10.1101/2021.10.14.464368","is_oa":true,"landing_page_url":"https://doi.org/10.1101/2021.10.14.464368","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2021/10/14/2021.10.14.464368.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},{"id":"pmh:oai:pubmedcentral.nih.gov:10830421","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10830421","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10830421/pdf/41589_2023_Article_1452.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nat Chem Biol","raw_type":"Text"},{"id":"pmid:37884807","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37884807","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature chemical biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1038/s41589-023-01452-w","doi":"https://doi.org/10.1038/s41589-023-01452-w","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41589-023-01452-w","pdf_url":"https://www.nature.com/articles/s41589-023-01452-w.pdf","source":{"id":"https://openalex.org/S51309854","display_name":"Nature Chemical Biology","issn_l":"1552-4450","issn":["1552-4450","1552-4469"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nature Chemical Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1346571950","display_name":null,"funder_award_id":"2021R1A2C2007573","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"},{"id":"https://openalex.org/G138333412","display_name":null,"funder_award_id":"NRF-2018R1A2A3075389","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G1442093329","display_name":null,"funder_award_id":"2018R1A2A3075389","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G1492580079","display_name":null,"funder_award_id":"NRF-2022M3A9I2082294","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G1551050494","display_name":null,"funder_award_id":"2022M3A9I2082294","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G1581234594","display_name":null,"funder_award_id":"NRF-2022M3E5E8081185","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G1622723095","display_name":null,"funder_award_id":"IBS-R008-D1","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G1799564886","display_name":null,"funder_award_id":"KGM5392212","funder_id":"https://openalex.org/F4320322110","funder_display_name":"Korea Research Institute of Bioscience and Biotechnology"},{"id":"https://openalex.org/G1802548948","display_name":null,"funder_award_id":"SSTF-BA2201-08","funder_id":"https://openalex.org/F4320328437","funder_display_name":"Samsung Science and Technology Foundation"},{"id":"https://openalex.org/G2006193230","display_name":null,"funder_award_id":"NRF-2019R1A2C3008463","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G2169336704","display_name":null,"funder_award_id":"NRF-2022R1C1C2004982","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G2214948142","display_name":null,"funder_award_id":"NRF-2021R1A2C2009336","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G2304812787","display_name":null,"funder_award_id":"2022M3A9I2082294","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G2337071106","display_name":null,"funder_award_id":"NRF-2017R1A5A1015366","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G2402660949","display_name":null,"funder_award_id":"IBS-R008-D1","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G2643796712","display_name":null,"funder_award_id":"IBS-R008-D1","funder_id":"https://openalex.org/F4320326441","funder_display_name":"Institute for Basic Science"},{"id":"https://openalex.org/G322481348","display_name":null,"funder_award_id":"HU20C0326","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G3264138898","display_name":null,"funder_award_id":"NRF 2022R1A2B5B03001658","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G3969051666","display_name":null,"funder_award_id":"NRF\u20102017R1A5A1015366","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G4001076239","display_name":null,"funder_award_id":"21-BR-01-11","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G4021957986","display_name":null,"funder_award_id":"23-BR-04-04","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G4529589349","display_name":null,"funder_award_id":"2019M3E5D3073104","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G4600871193","display_name":null,"funder_award_id":"2021R1A5A1033157","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G5201466859","display_name":null,"funder_award_id":"IBS-R008-D1","funder_id":"https://openalex.org/F4320321292","funder_display_name":"Seoul National University"},{"id":"https://openalex.org/G5417615882","display_name":null,"funder_award_id":"HU20C0326","funder_id":"https://openalex.org/F4320322107","funder_display_name":"Korea Health Industry Development Institute"},{"id":"https://openalex.org/G5433976708","display_name":null,"funder_award_id":"NRF-2019M3E5D3073104","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G5526961238","display_name":null,"funder_award_id":"NRF-2021R1A5A1033157","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G5598398694","display_name":null,"funder_award_id":"NRF-2022M3H9A2096199","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G5631362762","display_name":null,"funder_award_id":"2019R1A2C2089484","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G5711340399","display_name":null,"funder_award_id":"NRF-2021R1A5A1033157","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G6021703449","display_name":null,"funder_award_id":"2021R1A5A1033157","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G6127215812","display_name":null,"funder_award_id":"2017K1A1A2013124","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G6310749854","display_name":null,"funder_award_id":"NRF-2019M3E5D3073104","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G6778206002","display_name":null,"funder_award_id":"NRF 2017K1A1A2013124","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G7572747708","display_name":null,"funder_award_id":"2018R1A2A3075389","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"},{"id":"https://openalex.org/G7750438674","display_name":null,"funder_award_id":"BR-01-03","funder_id":"https://openalex.org/F4320318413","funder_display_name":"Korea Brain Research Institute"},{"id":"https://openalex.org/G8099688578","display_name":null,"funder_award_id":"23-BR-01-03","funder_id":"https://openalex.org/F4320328359","funder_display_name":"Ministry of Science and ICT, South Korea"},{"id":"https://openalex.org/G8434136596","display_name":null,"funder_award_id":"NRF-2019M3E5D3073104","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"},{"id":"https://openalex.org/G848733465","display_name":null,"funder_award_id":"NRF-2021R1A5A1033157","funder_id":"https://openalex.org/F4320320671","funder_display_name":"National Research Foundation"},{"id":"https://openalex.org/G8661181119","display_name":null,"funder_award_id":"2017R1A5A1015366","funder_id":"https://openalex.org/F4320322120","funder_display_name":"National Research Foundation of Korea"},{"id":"https://openalex.org/G8739444332","display_name":null,"funder_award_id":"R008-D1","funder_id":"https://openalex.org/F4320326441","funder_display_name":"Institute for Basic Science"}],"funders":[{"id":"https://openalex.org/F4320318413","display_name":"Korea Brain Research Institute","ror":"https://ror.org/055zd7d59"},{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320321292","display_name":"Seoul National University","ror":"https://ror.org/04h9pn542"},{"id":"https://openalex.org/F4320322107","display_name":"Korea Health Industry Development Institute","ror":"https://ror.org/00fdzyk40"},{"id":"https://openalex.org/F4320322110","display_name":"Korea Research Institute of Bioscience and Biotechnology","ror":"https://ror.org/03ep23f07"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"},{"id":"https://openalex.org/F4320324161","display_name":"Korea Advanced Institute of Science and Technology","ror":"https://ror.org/05apxxy63"},{"id":"https://openalex.org/F4320326441","display_name":"Institute for Basic Science","ror":"https://ror.org/00y0zf565"},{"id":"https://openalex.org/F4320328359","display_name":"Ministry of Science and ICT, South Korea","ror":"https://ror.org/01wpjm123"},{"id":"https://openalex.org/F4320328437","display_name":"Samsung Science and Technology Foundation","ror":"https://ror.org/00gjmje40"},{"id":"https://openalex.org/F4320332195","display_name":"Samsung","ror":"https://ror.org/04w3jy968"},{"id":"https://openalex.org/F4320334879","display_name":"Korea Evaluation Institute of Industrial Technology","ror":"https://ror.org/03z9cwa38"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387965110.pdf","grobid_xml":"https://content.openalex.org/works/W4387965110.grobid-xml"},"referenced_works_count":88,"referenced_works":["https://openalex.org/W1498448116","https://openalex.org/W1535750970","https://openalex.org/W1701470710","https://openalex.org/W1800061482","https://openalex.org/W1846180325","https://openalex.org/W1923689855","https://openalex.org/W1965903580","https://openalex.org/W1981748166","https://openalex.org/W1990828270","https://openalex.org/W1997183854","https://openalex.org/W2005650337","https://openalex.org/W2005792416","https://openalex.org/W2012034410","https://openalex.org/W2023949937","https://openalex.org/W2034405939","https://openalex.org/W2035156848","https://openalex.org/W2035898183","https://openalex.org/W2036253883","https://openalex.org/W2042033604","https://openalex.org/W2065324486","https://openalex.org/W2071599767","https://openalex.org/W2075471735","https://openalex.org/W2080754372","https://openalex.org/W2081665845","https://openalex.org/W2082516237","https://openalex.org/W2082778070","https://openalex.org/W2098157209","https://openalex.org/W2101117598","https://openalex.org/W2105167594","https://openalex.org/W2120811558","https://openalex.org/W2128606426","https://openalex.org/W2135656427","https://openalex.org/W2150068695","https://openalex.org/W2154068452","https://openalex.org/W2160737695","https://openalex.org/W2162862678","https://openalex.org/W2167345470","https://openalex.org/W2167795167","https://openalex.org/W2169575504","https://openalex.org/W2180760460","https://openalex.org/W2220950257","https://openalex.org/W2327357942","https://openalex.org/W2503158277","https://openalex.org/W2503851771","https://openalex.org/W2523662230","https://openalex.org/W2549188196","https://openalex.org/W2585958136","https://openalex.org/W2601885162","https://openalex.org/W2604738787","https://openalex.org/W2611090362","https://openalex.org/W2697643565","https://openalex.org/W2754373993","https://openalex.org/W2765968230","https://openalex.org/W2768451093","https://openalex.org/W2773803332","https://openalex.org/W2783829661","https://openalex.org/W2802800214","https://openalex.org/W2810092780","https://openalex.org/W2888618670","https://openalex.org/W2889921316","https://openalex.org/W2899664253","https://openalex.org/W2899760200","https://openalex.org/W2900569176","https://openalex.org/W2907218940","https://openalex.org/W2944797582","https://openalex.org/W2945112778","https://openalex.org/W2946554731","https://openalex.org/W2954454316","https://openalex.org/W2973648545","https://openalex.org/W2980472864","https://openalex.org/W2981179816","https://openalex.org/W2982570926","https://openalex.org/W2983713778","https://openalex.org/W2991886786","https://openalex.org/W2996045117","https://openalex.org/W3003960907","https://openalex.org/W3022144399","https://openalex.org/W3024644845","https://openalex.org/W3024928082","https://openalex.org/W3091843058","https://openalex.org/W3106539179","https://openalex.org/W3131597949","https://openalex.org/W3160119673","https://openalex.org/W3169724331","https://openalex.org/W3177828909","https://openalex.org/W3192933072","https://openalex.org/W4210577179","https://openalex.org/W4250908540"],"related_works":["https://openalex.org/W4387955517","https://openalex.org/W4402270301","https://openalex.org/W4413641481","https://openalex.org/W2081325408","https://openalex.org/W4387379492","https://openalex.org/W3121220281","https://openalex.org/W6962772893","https://openalex.org/W1834076678","https://openalex.org/W6906480410","https://openalex.org/W1990432086"],"abstract_inverted_index":{"Abstract":[0],"Targeting":[1],"proximity-labeling":[2],"enzymes":[3],"to":[4],"specific":[5],"cellular":[6,107],"locations":[7],"is":[8,56,66,137],"a":[9,23,138],"viable":[10],"strategy":[11],"for":[12,81,143],"profiling":[13],"subcellular":[14],"proteomes.":[15],"Here,":[16],"we":[17],"generated":[18],"transgenic":[19],"mice":[20],"(MAX-Tg)":[21],"expressing":[22],"mitochondrial":[24,41,60,139,145],"matrix-targeted":[25],"ascorbate":[26],"peroxidase.":[27],"Comparative":[28],"analysis":[29,71],"of":[30,40,62,94,112],"matrix":[31,61],"proteomes":[32],"from":[33],"the":[34,59,90,149],"muscle":[35,63,120,150],"tissues":[36,64],"showed":[37],"differential":[38],"enrichment":[39],"proteins.":[42],"We":[43],"found":[44],"that":[45,135],"reticulon":[46],"4-interacting":[47],"protein":[48],"1":[49],"(RTN4IP1),":[50],"also":[51],"known":[52],"as":[53],"optic":[54],"atrophy-10,":[55],"enriched":[57],"in":[58,73,83,115,118,148],"and":[65,72,105],"an":[67,78],"NADPH":[68],"oxidoreductase.":[69],"Interactome":[70],"vitro":[74],"enzymatic":[75],"assays":[76],"revealed":[77],"essential":[79,142],"role":[80],"RTN4IP1":[82,136],"coenzyme":[84],"Q":[85],"(CoQ)":[86],"biosynthesis":[87],"by":[88,125],"regulating":[89],"O":[91],"-methylation":[92],"activity":[93,147],"COQ3.":[95],"Rtn4ip1-":[96],"knockout":[97],"myoblasts":[98],"had":[99],"markedly":[100],"decreased":[101],"CoQ":[102],"9":[103],"levels":[104],"impaired":[106,119],"respiration.":[108],"Furthermore,":[109],"muscle-specific":[110],"knockdown":[111],"d":[113],"Rtn4ip1":[114],"flies":[116],"resulted":[117],"function,":[121],"which":[122],"was":[123],"reversed":[124],"dietary":[126],"supplementation":[127],"with":[128],"soluble":[129],"CoQ.":[130],"Collectively,":[131],"these":[132],"results":[133],"demonstrate":[134],"NAD(P)H":[140],"oxidoreductase":[141],"supporting":[144],"respiration":[146],"tissue.":[151]},"counts_by_year":[{"year":2026,"cited_by_count":14},{"year":2025,"cited_by_count":14},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2023-10-28T00:00:00"}