{"id":"https://openalex.org/W4387962250","doi":"https://doi.org/10.1200/op.2023.19.11_suppl.420","title":"Development of ovarian cancer biomarker electronic clinical quality measure: Lessons learned.","display_name":"Development of ovarian cancer biomarker electronic clinical quality measure: Lessons learned.","publication_year":2023,"publication_date":"2023-10-26","ids":{"openalex":"https://openalex.org/W4387962250","doi":"https://doi.org/10.1200/op.2023.19.11_suppl.420"},"language":"en","primary_location":{"id":"doi:10.1200/op.2023.19.11_suppl.420","doi":"https://doi.org/10.1200/op.2023.19.11_suppl.420","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1200/op.2023.19.11_suppl.420","pdf_url":null,"source":{"id":"https://openalex.org/S4210202425","display_name":"JCO Oncology Practice","issn_l":"2688-1527","issn":["2688-1527","2688-1535"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCO Oncology Practice","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065396077","display_name":"Caitlin Murray Drumheller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1315885867","display_name":"American Society of Clinical Oncology","ror":"https://ror.org/04fy6j421","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1315885867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caitlin Drumheller","raw_affiliation_strings":["American Society of Clinical Oncology, Alexandria, VA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"American Society of Clinical Oncology, Alexandria, VA","institution_ids":["https://openalex.org/I1315885867"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032378308","display_name":"Alexi A. Wright","orcid":"https://orcid.org/0000-0002-9776-7114","observed_orcids":["https://orcid.org/0000-0002-9776-7114"]},"institutions":[{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexi A. Wright","raw_affiliation_strings":["Dana-Farber Cancer Institute, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dana-Farber Cancer Institute, Boston, MA","institution_ids":["https://openalex.org/I4210117453"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059048867","display_name":"Ying L. Liu","orcid":"https://orcid.org/0000-0001-5790-851X","observed_orcids":["https://orcid.org/0000-0001-5790-851X"]},"institutions":[{"id":"https://openalex.org/I1334819555","display_name":"Memorial Sloan Kettering Cancer Center","ror":"https://ror.org/02yrq0923","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1334819555"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ying L Liu","raw_affiliation_strings":["Memorial Sloan Kettering Cancer Center, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Memorial Sloan Kettering Cancer Center, New York, NY","institution_ids":["https://openalex.org/I1334819555"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"19","issue":"11_suppl","first_page":"420","last_page":"420"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10769","display_name":"BRCA gene mutations in cancer","score":0.9761000275611877,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.00989999994635582,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12871","display_name":"Healthcare Quality and Management","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"ovarian cancer","score":0.9900000095367432},{"id":"https://openalex.org/keywords/electronic-clinical-quality-measures","display_name":"electronic clinical quality measures","score":0.8009999990463257},{"id":"https://openalex.org/keywords/quality-of-cancer-care","display_name":"quality of cancer care","score":0.6520000100135803},{"id":"https://openalex.org/keywords/clinical-workflow-analysis","display_name":"clinical workflow analysis","score":0.6019999980926514},{"id":"https://openalex.org/keywords/fhir","display_name":"FHIR","score":0.8309999704360962},{"id":"https://openalex.org/keywords/mcode","display_name":"MCODE","score":0.7400000095367432},{"id":"https://openalex.org/keywords/precision-oncology","display_name":"precision oncology","score":0.5600000023841858}],"concepts":[{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.6351994276046753},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6172947883605957},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4211888611316681},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.38151949644088745},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.3546626567840576},{"id":"https://openalex.org/C19527891","wikidata":"https://www.wikidata.org/wiki/Q1120908","display_name":"Medical physics","level":1,"score":0.3359314203262329},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3176000714302063},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.09434151649475098}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/op.2023.19.11_suppl.420","doi":"https://doi.org/10.1200/op.2023.19.11_suppl.420","is_oa":false,"landing_page_url":"http://dx.doi.org/10.1200/op.2023.19.11_suppl.420","pdf_url":null,"source":{"id":"https://openalex.org/S4210202425","display_name":"JCO Oncology Practice","issn_l":"2688-1527","issn":["2688-1527","2688-1535"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCO Oncology Practice","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306202","display_name":"Gordon and Betty Moore Foundation","ror":"https://ror.org/006wxqw41"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4388200110","https://openalex.org/W4281688319","https://openalex.org/W4403251470","https://openalex.org/W2947013444","https://openalex.org/W4410815049","https://openalex.org/W2922471193","https://openalex.org/W4295300125","https://openalex.org/W4312139845","https://openalex.org/W4376616175","https://openalex.org/W4295226820"],"abstract_inverted_index":{"420":[0],"Background:":[1],"ASCO":[2,38,236,264,312],"received":[3],"funding":[4],"from":[5,137],"the":[6,41,55,125,166,201,209,217,240,248,253,299,317,340,343,350,360],"Gordon":[7],"&":[8],"Betty":[9],"Moore":[10],"Foundation\u2019s":[11],"Diagnostic":[12],"Excellence":[13],"Initiative":[14],"to":[15,53,91,105,120,139,198,222,238,267,315,322],"develop":[16],"and":[17,77,81,96,114,158,188,207,234,258,283,297,301],"test":[18],"a":[19,33,107,143,155,177,192],"biomarker":[20],"electronic":[21],"Clinical":[22,242],"Quality":[23,243],"Measure":[24,244],"(eCQM)":[25],"in":[26,63,100,111,160,162,191,228,262,354],"ovarian":[27,65,167,229],"cancer.":[28],"Methods:":[29],"Working":[30],"collaboratively":[31],"with":[32,142],"Technical":[34],"Expert":[35],"Panel":[36],"(TEP),":[37],"staff":[39],"explored":[40],"development":[42,174],"of":[43,57,109,117,203,211,219,225,247,303,319,342,349],"an":[44,89,101,220],"eCQM,":[45],"Appropriate":[46],"Germline":[47],"Testing":[48],"for":[49,59,307],"Ovarian":[50],"Cancer":[51],"Patients":[52],"assess":[54,200,223],"rates":[56,224],"testing":[58,87,99,131,164,227,251,330],"BRCA1/2":[60,98,329],"germline":[61,95,122,163,226,328],"mutations":[62],"adult":[64],"cancer":[66,168,205,230,310,325],"patients.":[67],"The":[68],"measure":[69,134,173,321],"underwent":[70],"clinical":[71],"workflow":[72],"analysis;":[73],"feasibility;":[74],"face,":[75],"empiric,":[76],"data":[78,186,295,305],"element":[79],"validity;":[80],"signal-to-noise":[82],"reliability":[83],"testing.":[84,123],"Results:":[85],"Feasibility":[86],"indicated":[88,252],"inability":[90],"reliably":[92,199],"differentiate":[93],"between":[94],"somatic":[97],"eCQM":[102,221],"specification":[103],"due":[104],"both":[106],"lack":[108],"specificity":[110,190],"existing":[112],"codes,":[113],"inconsistent":[115],"use":[116,353],"appropriate":[118],"codes":[119],"reflect":[121],"Among":[124],"32":[126],"individual":[127],"clinicians":[128],"across":[129],"12":[130],"sites,":[132],"overall":[133],"performance":[135,147,156],"ranged":[136],"6.25":[138],"100":[140],"percent,":[141],"52.3":[144],"percent":[145,150],"mean":[146],"score":[148],"(95":[149],"CI":[151],"[39.9,":[152],"64.7]),":[153],"indicating":[154],"gap":[157],"variation":[159,261],"care":[161,206],"among":[165],"patient":[169],"population.":[170],"Conclusions:":[171],"This":[172],"effort":[175],"illustrated":[176],"scenario":[178],"where":[179,327],"medical":[180],"practice":[181],"has":[182],"advanced":[183],"beyond":[184],"current":[185],"availability":[187,300],"coding":[189],"way":[193],"that":[194,212],"impacts":[195],"stakeholder":[196],"ability":[197],"delivery":[202],"personalized":[204],"minimize":[208],"burden":[210],"measurement.":[213],"While":[214],"we":[215],"concluded":[216],"implementation":[218],"patients":[231],"was":[232],"infeasible":[233],"premature,":[235],"continues":[237],"advance":[239,268],"registry-based":[241],"(CQM)":[245],"version":[246],"measure,":[249,344],"as":[250,359],"CQM":[254],"is":[255,331],"reliable,":[256],"valid,":[257],"reflected":[259],"continued":[260],"care.":[263,311],"supports":[265],"efforts":[266],"towards":[269],"robust,":[270],"meaningful":[271],"digital":[272],"quality":[273,309],"measures":[274],"using":[275],"things":[276],"like":[277],"Fast":[278],"Healthcare":[279],"Interoperability":[280],"Resources":[281],"(FHIR)":[282],"Minimal":[284],"Common":[285],"Data":[286],"Elements":[287],"(mCODE)":[288],"initiatives,":[289],"which":[290],"will":[291,335],"enable":[292],"more":[293],"standardized":[294],"capture":[296],"increase":[298,347],"utility":[302],"granular":[304],"needed":[306],"assessing":[308],"also":[313,346],"seeks":[314],"expand":[316],"denominator":[318],"this":[320],"include":[323],"additional":[324],"types":[326],"appropriate.":[332],"Denominator":[333],"expansion":[334],"not":[336],"only":[337],"significantly":[338],"broaden":[339],"impact":[341],"but":[345],"longevity":[348],"measure\u2019s":[351],"potential":[352],"cross-cutting":[355],"reporting":[356],"initiatives":[357],"such":[358],"Merit-based":[361],"Incentive":[362],"Payment":[363],"System":[364],"(MIPS)":[365],"Value":[366],"Pathways":[367],"(MVPs).":[368]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2023-10-27T00:00:00"}