{"id":"https://openalex.org/W4387955157","doi":"https://doi.org/10.1134/s0006297923100176","title":"Catalytic and Electrocatalytic Mechanisms of Cytochromes P450 in the Development of Biosensors and Bioreactors","display_name":"Catalytic and Electrocatalytic Mechanisms of Cytochromes P450 in the Development of Biosensors and Bioreactors","publication_year":2023,"publication_date":"2023-10-01","ids":{"openalex":"https://openalex.org/W4387955157","doi":"https://doi.org/10.1134/s0006297923100176","pmid":"https://pubmed.ncbi.nlm.nih.gov/38105030"},"language":"en","primary_location":{"id":"doi:10.1134/s0006297923100176","doi":"https://doi.org/10.1134/s0006297923100176","is_oa":false,"landing_page_url":"https://doi.org/10.1134/s0006297923100176","pdf_url":null,"source":{"id":"https://openalex.org/S71215691","display_name":"Biochemistry (Moscow)","issn_l":"0006-2979","issn":["0006-2979","0320-9725","1608-3040"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320267","host_organization_name":"Pleiades Publishing","host_organization_lineage":["https://openalex.org/P4310320267","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Pleiades Publishing","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry (Moscow)","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028036113","display_name":"Polina I. Koroleva","orcid":"https://orcid.org/0000-0003-2802-5747","observed_orcids":["https://orcid.org/0000-0003-2802-5747"]},"institutions":[{"id":"https://openalex.org/I4210152028","display_name":"Institute of Biomedical Chemistry","ror":"https://ror.org/040wrkp27","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210152028"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Polina I. Koroleva","raw_affiliation_strings":["Institute of Biomedical Chemistry, Moscow, 119121, Russia","Institute of Biomedical Chemistry, 119121, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedical Chemistry, Moscow, 119121, Russia","institution_ids":["https://openalex.org/I4210152028"]},{"raw_affiliation_string":"Institute of Biomedical Chemistry, 119121, Moscow, Russia","institution_ids":["https://openalex.org/I4210152028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109558255","display_name":"Tatiana V. Bulko","orcid":"https://orcid.org/0009-0000-3732-2394","observed_orcids":["https://orcid.org/0009-0000-3732-2394"]},"institutions":[{"id":"https://openalex.org/I4210152028","display_name":"Institute of Biomedical Chemistry","ror":"https://ror.org/040wrkp27","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210152028"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Tatiana V. Bulko","raw_affiliation_strings":["Institute of Biomedical Chemistry, Moscow, 119121, Russia","Institute of Biomedical Chemistry, 119121, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedical Chemistry, Moscow, 119121, Russia","institution_ids":["https://openalex.org/I4210152028"]},{"raw_affiliation_string":"Institute of Biomedical Chemistry, 119121, Moscow, Russia","institution_ids":["https://openalex.org/I4210152028"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020350073","display_name":"L.E. Agafonova","orcid":"https://orcid.org/0000-0003-3874-6556","observed_orcids":["https://orcid.org/0000-0003-3874-6556"]},"institutions":[{"id":"https://openalex.org/I4210152028","display_name":"Institute of Biomedical Chemistry","ror":"https://ror.org/040wrkp27","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210152028"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Lyubov\u2019 E. Agafonova","raw_affiliation_strings":["Institute of Biomedical Chemistry, Moscow, 119121, Russia","Institute of Biomedical Chemistry, 119121, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedical Chemistry, Moscow, 119121, Russia","institution_ids":["https://openalex.org/I4210152028"]},{"raw_affiliation_string":"Institute of Biomedical Chemistry, 119121, Moscow, Russia","institution_ids":["https://openalex.org/I4210152028"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038643888","display_name":"Victoria V. Shumyantseva","orcid":"https://orcid.org/0000-0002-1509-7218","observed_orcids":["https://orcid.org/0000-0002-1509-7218"]},"institutions":[{"id":"https://openalex.org/I337778094","display_name":"Pirogov Russian National Research Medical University","ror":"https://ror.org/018159086","country_code":"RU","type":"education","lineage":["https://openalex.org/I337778094","https://openalex.org/I4210117042"]},{"id":"https://openalex.org/I4210152028","display_name":"Institute of Biomedical Chemistry","ror":"https://ror.org/040wrkp27","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110862","https://openalex.org/I4210152028"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Victoria V. Shumyantseva","raw_affiliation_strings":["Institute of Biomedical Chemistry, Moscow, 119121, Russia. viktoria.shumyantseva@ibmc.msk.ru","Pirogov Russian National Research Medical University, Moscow, 117997, Russia","Institute of Biomedical Chemistry, 119121, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Biomedical Chemistry, Moscow, 119121, Russia. viktoria.shumyantseva@ibmc.msk.ru","institution_ids":["https://openalex.org/I4210152028"]},{"raw_affiliation_string":"Pirogov Russian National Research Medical University, Moscow, 117997, Russia","institution_ids":["https://openalex.org/I337778094"]},{"raw_affiliation_string":"Institute of Biomedical Chemistry, 119121, Moscow, Russia","institution_ids":["https://openalex.org/I4210152028"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5038643888"],"corresponding_institution_ids":["https://openalex.org/I337778094","https://openalex.org/I4210152028"],"apc_list":null,"apc_paid":null,"fwci":0.1619,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.11978466,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"88","issue":"10","first_page":"1645","last_page":"1657"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.6230000257492065,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10212","display_name":"Electrochemical sensors and biosensors","score":0.6230000257492065,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization","score":0.3521000146865845,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11747","display_name":"Metal-Catalyzed Oxygenation Mechanisms","score":0.007600000128149986,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/electrocatalysis","display_name":"electrocatalysis","score":0.9779999852180481},{"id":"https://openalex.org/keywords/catalytic-mechanism","display_name":"catalytic mechanism","score":0.640999972820282},{"id":"https://openalex.org/keywords/biosensors","display_name":"biosensors","score":0.9779999852180481},{"id":"https://openalex.org/keywords/bioreactors","display_name":"bioreactors","score":0.9990000128746033},{"id":"https://openalex.org/keywords/reconstituted-enzyme-system","display_name":"reconstituted enzyme system","score":0.8379999995231628},{"id":"https://openalex.org/keywords/biotransformation","display_name":"biotransformation","score":0.9070000052452087},{"id":"https://openalex.org/keywords/enzyme-engineering","display_name":"enzyme engineering","score":0.30799999833106995}],"concepts":[{"id":"https://openalex.org/C27881333","wikidata":"https://www.wikidata.org/wiki/Q864895","display_name":"Biotransformation","level":3,"score":0.6910288333892822},{"id":"https://openalex.org/C160756335","wikidata":"https://www.wikidata.org/wiki/Q669391","display_name":"Biosensor","level":2,"score":0.5642675161361694},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.479265421628952},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4744473695755005},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.4654318690299988},{"id":"https://openalex.org/C526171541","wikidata":"https://www.wikidata.org/wiki/Q407693","display_name":"Cytochrome P450","level":3,"score":0.457526296377182},{"id":"https://openalex.org/C14036430","wikidata":"https://www.wikidata.org/wiki/Q3736076","display_name":"Function (biology)","level":2,"score":0.45338308811187744},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.45203202962875366},{"id":"https://openalex.org/C550995028","wikidata":"https://www.wikidata.org/wiki/Q10872","display_name":"Archaea","level":3,"score":0.4206695556640625},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.36997663974761963},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.36394816637039185},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.35334452986717224},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3261241018772125},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.13150256872177124},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11407861113548279},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08741787075996399},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0784803032875061}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001709","descriptor_name":"Biotechnology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001711","descriptor_name":"Biotransformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003577","descriptor_name":"Cytochrome P-450 Enzyme System","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015374","descriptor_name":"Biosensing Techniques","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D019149","descriptor_name":"Bioreactors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1134/s0006297923100176","doi":"https://doi.org/10.1134/s0006297923100176","is_oa":false,"landing_page_url":"https://doi.org/10.1134/s0006297923100176","pdf_url":null,"source":{"id":"https://openalex.org/S71215691","display_name":"Biochemistry (Moscow)","issn_l":"0006-2979","issn":["0006-2979","0320-9725","1608-3040"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320267","host_organization_name":"Pleiades Publishing","host_organization_lineage":["https://openalex.org/P4310320267","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Pleiades Publishing","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry (Moscow)","raw_type":"journal-article"},{"id":"pmid:38105030","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/38105030","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry. Biokhimiia","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":90,"referenced_works":["https://openalex.org/W62548535","https://openalex.org/W175067509","https://openalex.org/W1247495390","https://openalex.org/W1485387786","https://openalex.org/W1495000055","https://openalex.org/W1497083865","https://openalex.org/W1526170069","https://openalex.org/W1603225698","https://openalex.org/W1872245393","https://openalex.org/W1877076446","https://openalex.org/W1964135958","https://openalex.org/W1968326611","https://openalex.org/W1970982745","https://openalex.org/W1975262546","https://openalex.org/W1976686930","https://openalex.org/W1977946626","https://openalex.org/W1981311160","https://openalex.org/W1981924651","https://openalex.org/W1985152937","https://openalex.org/W1986607177","https://openalex.org/W2000694785","https://openalex.org/W2000983010","https://openalex.org/W2002074698","https://openalex.org/W2003105919","https://openalex.org/W2009095032","https://openalex.org/W2010427019","https://openalex.org/W2012801837","https://openalex.org/W2017715477","https://openalex.org/W2018873107","https://openalex.org/W2027324760","https://openalex.org/W2031774647","https://openalex.org/W2038346301","https://openalex.org/W2043758058","https://openalex.org/W2045026040","https://openalex.org/W2047981591","https://openalex.org/W2052704239","https://openalex.org/W2064638034","https://openalex.org/W2065516217","https://openalex.org/W2066312456","https://openalex.org/W2075903510","https://openalex.org/W2076202514","https://openalex.org/W2077621515","https://openalex.org/W2097100227","https://openalex.org/W2100255974","https://openalex.org/W2109364613","https://openalex.org/W2119951672","https://openalex.org/W2123998092","https://openalex.org/W2128929539","https://openalex.org/W2135346969","https://openalex.org/W2153513447","https://openalex.org/W2154591315","https://openalex.org/W2325137743","https://openalex.org/W2332408197","https://openalex.org/W2345539723","https://openalex.org/W2464575859","https://openalex.org/W2588580023","https://openalex.org/W2604245933","https://openalex.org/W2626356663","https://openalex.org/W2755545862","https://openalex.org/W2762109701","https://openalex.org/W2774839461","https://openalex.org/W2804328020","https://openalex.org/W2804420022","https://openalex.org/W2886246311","https://openalex.org/W2888589312","https://openalex.org/W2889255723","https://openalex.org/W2901876222","https://openalex.org/W2912241303","https://openalex.org/W2974228962","https://openalex.org/W3004308411","https://openalex.org/W3004381558","https://openalex.org/W3014302046","https://openalex.org/W3014920422","https://openalex.org/W3015180867","https://openalex.org/W3030071003","https://openalex.org/W3116906927","https://openalex.org/W3128763805","https://openalex.org/W3129769365","https://openalex.org/W3186925921","https://openalex.org/W3194229788","https://openalex.org/W4205191240","https://openalex.org/W4210918648","https://openalex.org/W4211019819","https://openalex.org/W4211244055","https://openalex.org/W4235118812","https://openalex.org/W4297324804","https://openalex.org/W4297326669","https://openalex.org/W4297492367","https://openalex.org/W4313597539","https://openalex.org/W4362611120"],"related_works":["https://openalex.org/W2289993664","https://openalex.org/W2177344547","https://openalex.org/W4406642598","https://openalex.org/W2031774647","https://openalex.org/W4380681848","https://openalex.org/W2888589312","https://openalex.org/W2058252718","https://openalex.org/W2075812888","https://openalex.org/W2029906456","https://openalex.org/W3211206733"],"abstract_inverted_index":{"Cytochromes":[0],"P450":[1,43],"are":[2],"a":[3],"unique":[4],"family":[5],"of":[6,12,26,39,51,60,71],"enzymes":[7],"found":[8],"in":[9,47,57],"all":[10],"Kingdoms":[11],"living":[13],"organisms":[14],"(animals,":[15],"bacteria,":[16],"plants,":[17],"fungi,":[18],"and":[19,28,49,53,62,77],"archaea),":[20],"whose":[21],"main":[22,55],"function":[23],"is":[24],"biotransformation":[25],"exogenous":[27],"endogenous":[29],"compounds.":[30],"The":[31],"review":[32],"discusses":[33],"approaches":[34],"to":[35],"enhancing":[36],"the":[37,58,68],"efficiency":[38],"electrocatalysis":[40],"by":[41],"cytochromes":[42,72],"for":[44,80],"their":[45,81],"use":[46],"biotechnology":[48],"design":[50],"biosensors":[52],"describes":[54],"methods":[56],"development":[59],"reconstituted":[61],"electrochemical":[63],"catalytic":[64],"systems":[65],"based":[66],"on":[67],"biochemical":[69],"mechanism":[70],"P450,":[73],"as":[74,76],"well":[75],"modern":[78],"trends":[79],"practical":[82],"application.":[83]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2023-10-27T00:00:00"}