{"id":"https://openalex.org/W4387948817","doi":"https://doi.org/10.1371/journal.pone.0293326","title":"HIV-1 subtype diversity and immuno-virological outcomes among adolescents failing antiretroviral therapy in Cameroon: A cohort study","display_name":"HIV-1 subtype diversity and immuno-virological outcomes among adolescents failing antiretroviral therapy in Cameroon: A cohort study","publication_year":2023,"publication_date":"2023-10-25","ids":{"openalex":"https://openalex.org/W4387948817","doi":"https://doi.org/10.1371/journal.pone.0293326","pmid":"https://pubmed.ncbi.nlm.nih.gov/37878637","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10599502"},"language":"en","primary_location":{"id":"doi:10.1371/journal.pone.0293326","doi":"https://doi.org/10.1371/journal.pone.0293326","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1371/journal.pone.0293326","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0293326&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0293326&type=printable","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046164102","display_name":"Willy Pabo","orcid":"https://orcid.org/0000-0002-5194-6715","observed_orcids":["https://orcid.org/0000-0002-5194-6715"]},"institutions":[{"id":"https://openalex.org/I1331070479","display_name":"Universit\u00e9 de Yaound\u00e9 I","ror":"https://ror.org/022zbs961","country_code":"CM","type":"education","lineage":["https://openalex.org/I1331070479"]},{"id":"https://openalex.org/I144693123","display_name":"University of Buea","ror":"https://ror.org/041kdhz15","country_code":"CM","type":"education","lineage":["https://openalex.org/I144693123"]},{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM"],"is_corresponding":true,"raw_author_name":"Willy Le roi Togna Pabo","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon","Faculty of Science, University of Buea, Buea, Cameroon"],"raw_orcid":"https://orcid.org/0000-0002-5194-6715","affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]},{"raw_affiliation_string":"Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I1331070479"]},{"raw_affiliation_string":"Faculty of Science, University of Buea, Buea, Cameroon","institution_ids":["https://openalex.org/I144693123"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078478462","display_name":"Joseph Fokam","orcid":"https://orcid.org/0000-0002-1501-2763","observed_orcids":["https://orcid.org/0000-0002-1501-2763"]},"institutions":[{"id":"https://openalex.org/I1331070479","display_name":"Universit\u00e9 de Yaound\u00e9 I","ror":"https://ror.org/022zbs961","country_code":"CM","type":"education","lineage":["https://openalex.org/I1331070479"]},{"id":"https://openalex.org/I144693123","display_name":"University of Buea","ror":"https://ror.org/041kdhz15","country_code":"CM","type":"education","lineage":["https://openalex.org/I144693123"]},{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]},{"id":"https://openalex.org/I4210137632","display_name":"Ministry of Public Health","ror":"https://ror.org/04bgfrg80","country_code":"CM","type":"government","lineage":["https://openalex.org/I4210137632"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Joseph Fokam","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","Faculty of Health Sciences, University of Buea, Buea, Cameroon","Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon","National HIV Drug Resistance Group, Ministry of Public Health, Yaound\u00e9, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]},{"raw_affiliation_string":"Faculty of Health Sciences, University of Buea, Buea, Cameroon","institution_ids":["https://openalex.org/I144693123"]},{"raw_affiliation_string":"Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I1331070479"]},{"raw_affiliation_string":"National HIV Drug Resistance Group, Ministry of Public Health, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210137632"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057199054","display_name":"Debimeh Njume","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1331070479","display_name":"Universit\u00e9 de Yaound\u00e9 I","ror":"https://ror.org/022zbs961","country_code":"CM","type":"education","lineage":["https://openalex.org/I1331070479"]},{"id":"https://openalex.org/I144693123","display_name":"University of Buea","ror":"https://ror.org/041kdhz15","country_code":"CM","type":"education","lineage":["https://openalex.org/I144693123"]},{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Debimeh Njume","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","Faculty of Health Sciences, University of Buea, Buea, Cameroon","Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]},{"raw_affiliation_string":"Faculty of Health Sciences, University of Buea, Buea, Cameroon","institution_ids":["https://openalex.org/I144693123"]},{"raw_affiliation_string":"Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I1331070479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108775788","display_name":"D\u00e9sir\u00e9 Takou","orcid":"https://orcid.org/0000-0003-2601-7508","observed_orcids":["https://orcid.org/0000-0003-2601-7508"]},"institutions":[{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"D\u00e9sir\u00e9 Takou","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023984688","display_name":"Maria Mercedes Santoro","orcid":"https://orcid.org/0000-0002-6228-1114","observed_orcids":["https://orcid.org/0000-0002-6228-1114"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria-Mercedes Santoro","raw_affiliation_strings":["University of Rome Tor Vergata, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rome Tor Vergata, Rome, Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041142168","display_name":"Raymond Babila Nyasa","orcid":"https://orcid.org/0000-0001-5916-0058","observed_orcids":["https://orcid.org/0000-0001-5916-0058"]},"institutions":[{"id":"https://openalex.org/I144693123","display_name":"University of Buea","ror":"https://ror.org/041kdhz15","country_code":"CM","type":"education","lineage":["https://openalex.org/I144693123"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Raymond Babila Nyasa","raw_affiliation_strings":["Faculty of Science, University of Buea, Buea, Cameroon"],"raw_orcid":"https://orcid.org/0000-0001-5916-0058","affiliations":[{"raw_affiliation_string":"Faculty of Science, University of Buea, Buea, Cameroon","institution_ids":["https://openalex.org/I144693123"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084242627","display_name":"Collins Ambe Chenwi","orcid":"https://orcid.org/0000-0002-6749-1436","observed_orcids":["https://orcid.org/0000-0002-6749-1436"]},"institutions":[{"id":"https://openalex.org/I1331070479","display_name":"Universit\u00e9 de Yaound\u00e9 I","ror":"https://ror.org/022zbs961","country_code":"CM","type":"education","lineage":["https://openalex.org/I1331070479"]},{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Collins Chenwi","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]},{"raw_affiliation_string":"Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I1331070479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093126885","display_name":"Marie Laure Mpouel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1331070479","display_name":"Universit\u00e9 de Yaound\u00e9 I","ror":"https://ror.org/022zbs961","country_code":"CM","type":"education","lineage":["https://openalex.org/I1331070479"]},{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Marie Laure Mpouel","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]},{"raw_affiliation_string":"Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I1331070479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004858539","display_name":"Gr\u00e2ce Angong Beloumou","orcid":"https://orcid.org/0000-0002-6870-7366","observed_orcids":["https://orcid.org/0000-0002-6870-7366"]},"institutions":[{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Grace Beloumou","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037945823","display_name":"Ez\u00e9chiel Ngoufack Jagni Semengue","orcid":"https://orcid.org/0000-0001-8768-2371","observed_orcids":["https://orcid.org/0000-0001-8768-2371"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]},{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM","IT"],"is_corresponding":false,"raw_author_name":"Ezechiel Semengue Ngoufack Jagni","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","Evangelic University of Cameroon, Bandjoun, Cameroon","University of Rome Tor Vergata, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]},{"raw_affiliation_string":"Evangelic University of Cameroon, Bandjoun, Cameroon","institution_ids":[]},{"raw_affiliation_string":"University of Rome Tor Vergata, Rome, Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020369127","display_name":"Alex Durand Nka","orcid":"https://orcid.org/0000-0002-9358-8661","observed_orcids":["https://orcid.org/0000-0002-9358-8661"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]},{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM","IT"],"is_corresponding":false,"raw_author_name":"Alex Durand Nka","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","Evangelic University of Cameroon, Bandjoun, Cameroon","University of Rome Tor Vergata, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]},{"raw_affiliation_string":"Evangelic University of Cameroon, Bandjoun, Cameroon","institution_ids":[]},{"raw_affiliation_string":"University of Rome Tor Vergata, Rome, Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088139682","display_name":"Aude Christelle Ka\u2019e","orcid":"https://orcid.org/0000-0002-2381-4299","observed_orcids":["https://orcid.org/0000-0002-2381-4299"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]},{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM","IT"],"is_corresponding":false,"raw_author_name":"Aude Christelle Ka\u2019e","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","University of Rome Tor Vergata, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]},{"raw_affiliation_string":"University of Rome Tor Vergata, Rome, Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109441325","display_name":"Georges T\u00e9to","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Georges Teto","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109444903","display_name":"B\u00e9atrice Dambaya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Beatrice Dambaya","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078087795","display_name":"Sandrine Claire Ndjeyep Djupsa","orcid":"https://orcid.org/0009-0001-7903-6182","observed_orcids":["https://orcid.org/0009-0001-7903-6182"]},"institutions":[{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Sandrine Djupsa","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077740482","display_name":"Davy Gouissi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1331070479","display_name":"Universit\u00e9 de Yaound\u00e9 I","ror":"https://ror.org/022zbs961","country_code":"CM","type":"education","lineage":["https://openalex.org/I1331070479"]},{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Davy Hyacinthe Gouissi Anguechia","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]},{"raw_affiliation_string":"Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I1331070479"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030304616","display_name":"Evariste Molimbou","orcid":"https://orcid.org/0009-0004-8359-3178","observed_orcids":["https://orcid.org/0009-0004-8359-3178"]},"institutions":[{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Molimbou Evariste","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058021222","display_name":"Cedric Kamta","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Cedric Kamta","raw_affiliation_strings":["Mfou District Hospital, Mfou, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mfou District Hospital, Mfou, Cameroon","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071504344","display_name":"Lionel Armel Bala","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802063107","display_name":"Mpilo Central Hospital","ror":"https://ror.org/05d9wmt54","country_code":"ZW","type":"healthcare","lineage":["https://openalex.org/I2802063107"]}],"countries":["ZW"],"is_corresponding":false,"raw_author_name":"Lionel Bala","raw_affiliation_strings":["Mbalmayo District Hospital, Mbalmayo, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mbalmayo District Hospital, Mbalmayo, Cameroon","institution_ids":["https://openalex.org/I2802063107"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087954145","display_name":"Virginie Lambo","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Virginie Lambo","raw_affiliation_strings":["Nkomo Integrated Health Center, Nkomo, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nkomo Integrated Health Center, Nkomo, Cameroon","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082771377","display_name":"Gregory Edie Halle-Ekane","orcid":"https://orcid.org/0000-0003-4304-9210","observed_orcids":["https://orcid.org/0000-0003-4304-9210"]},"institutions":[{"id":"https://openalex.org/I144693123","display_name":"University of Buea","ror":"https://ror.org/041kdhz15","country_code":"CM","type":"education","lineage":["https://openalex.org/I144693123"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Edie Gregory Halle-Ekane","raw_affiliation_strings":["Faculty of Health Sciences, University of Buea, Buea, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Health Sciences, University of Buea, Buea, Cameroon","institution_ids":["https://openalex.org/I144693123"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084589140","display_name":"Vittorio Colizzi","orcid":"https://orcid.org/0000-0003-0007-8580","observed_orcids":["https://orcid.org/0000-0003-0007-8580"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]},{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM","IT"],"is_corresponding":false,"raw_author_name":"Vittorio Colizzi","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","Evangelic University of Cameroon, Bandjoun, Cameroon","University of Rome Tor Vergata, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]},{"raw_affiliation_string":"Evangelic University of Cameroon, Bandjoun, Cameroon","institution_ids":[]},{"raw_affiliation_string":"University of Rome Tor Vergata, Rome, Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091721224","display_name":"Carlo Federico Perno","orcid":"https://orcid.org/0000-0002-0825-5388","observed_orcids":["https://orcid.org/0000-0002-0825-5388"]},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]},{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]},{"id":"https://openalex.org/I4210123352","display_name":"Bambino Ges\u00f9 Children's Hospital","ror":"https://ror.org/02sy42d13","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210123352","https://openalex.org/I4210153126"]}],"countries":["CM","IT"],"is_corresponding":false,"raw_author_name":"Carlo Federico Perno","raw_affiliation_strings":["Bambino Gesu Pediatric Hospital, Rome, Italy","Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","University of Rome Tor Vergata, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bambino Gesu Pediatric Hospital, Rome, Italy","institution_ids":["https://openalex.org/I4210123352"]},{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]},{"raw_affiliation_string":"University of Rome Tor Vergata, Rome, Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052368236","display_name":"Alexis Ndjolo","orcid":"https://orcid.org/0000-0002-4951-9271","observed_orcids":["https://orcid.org/0000-0002-4951-9271"]},"institutions":[{"id":"https://openalex.org/I1331070479","display_name":"Universit\u00e9 de Yaound\u00e9 I","ror":"https://ror.org/022zbs961","country_code":"CM","type":"education","lineage":["https://openalex.org/I1331070479"]},{"id":"https://openalex.org/I4210091290","display_name":"Centre International De Reference Chantal Biya","ror":"https://ror.org/01a84bt29","country_code":"CM","type":"other","lineage":["https://openalex.org/I4210091290"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Alexis Ndjolo","raw_affiliation_strings":["Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chantal BIYA International Reference Centre for Research on HIV/AIDS prevention and management, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I4210091290"]},{"raw_affiliation_string":"Faculty of Medicine and Biomedical Sciences, Yaound\u00e9, Cameroon","institution_ids":["https://openalex.org/I1331070479"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025365310","display_name":"Roland N. Ndip","orcid":"https://orcid.org/0000-0003-0028-7024","observed_orcids":["https://orcid.org/0000-0003-0028-7024"]},"institutions":[{"id":"https://openalex.org/I144693123","display_name":"University of Buea","ror":"https://ror.org/041kdhz15","country_code":"CM","type":"education","lineage":["https://openalex.org/I144693123"]}],"countries":["CM"],"is_corresponding":false,"raw_author_name":"Roland Ndip Ndip","raw_affiliation_strings":["Faculty of Science, University of Buea, Buea, Cameroon"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Science, University of Buea, Buea, Cameroon","institution_ids":["https://openalex.org/I144693123"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5046164102"],"corresponding_institution_ids":["https://openalex.org/I1331070479","https://openalex.org/I144693123","https://openalex.org/I4210091290"],"apc_list":{"value":1805,"currency":"USD","value_usd":1805},"apc_paid":{"value":1805,"currency":"USD","value_usd":1805},"fwci":0.6709,"has_fulltext":true,"cited_by_count":7,"citation_normalized_percentile":{"value":0.62945081,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"18","issue":"10","first_page":"e0293326","last_page":"e0293326"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.5522000193595886,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.5522000193595886,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.23849999904632568,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.19099999964237213,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hiv-1-subtypes","display_name":"HIV-1 subtypes","score":0.8899999856948853},{"id":"https://openalex.org/keywords/perinatal-hiv-infection","display_name":"perinatal HIV infection","score":0.8199999928474426},{"id":"https://openalex.org/keywords/adolescents","display_name":"adolescents","score":0.9100000262260437},{"id":"https://openalex.org/keywords/antiretroviral-therapy-failure","display_name":"antiretroviral therapy failure","score":0.9330000281333923},{"id":"https://openalex.org/keywords/virologic-failure","display_name":"virological failure","score":0.9110000133514404},{"id":"https://openalex.org/keywords/viral-load","display_name":"viral load","score":0.7580000162124634},{"id":"https://openalex.org/keywords/crf02-ag","display_name":"CRF02_AG","score":0.9589999914169312},{"id":"https://openalex.org/keywords/hiv-1-recombinants","display_name":"HIV-1 recombinants","score":0.7360000014305115},{"id":"https://openalex.org/keywords/drug-resistance","display_name":"drug resistance","score":0.5189999938011169},{"id":"https://openalex.org/keywords/treatment-duration","display_name":"treatment duration","score":0.5529999732971191},{"id":"https://openalex.org/keywords/cameroon","display_name":"Cameroon","score":0.5400000214576721},{"id":"https://openalex.org/keywords/phylogenetic-analysis","display_name":"phylogenetic analysis","score":0.5740000009536743}],"concepts":[{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.7487285137176514},{"id":"https://openalex.org/C207103383","wikidata":"https://www.wikidata.org/wiki/Q3930246","display_name":"Hazard ratio","level":3,"score":0.7198002338409424},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.6378070712089539},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6285828351974487},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5769686698913574},{"id":"https://openalex.org/C72563966","wikidata":"https://www.wikidata.org/wiki/Q1303415","display_name":"Cohort","level":2,"score":0.5517237186431885},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.5221657752990723},{"id":"https://openalex.org/C2777813720","wikidata":"https://www.wikidata.org/wiki/Q1243018","display_name":"Coinfection","level":3,"score":0.5043576955795288},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.4793142080307007},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.45169517397880554},{"id":"https://openalex.org/C205545832","wikidata":"https://www.wikidata.org/wiki/Q17156455","display_name":"Young adult","level":2,"score":0.4425515830516815},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.38947078585624695},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3547115623950958},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32914531230926514},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.31843671202659607}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002163","descriptor_name":"Cameroon","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006679","descriptor_name":"HIV Seropositivity","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015497","descriptor_name":"HIV-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024882","descriptor_name":"Drug Resistance, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1371/journal.pone.0293326","doi":"https://doi.org/10.1371/journal.pone.0293326","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1371/journal.pone.0293326","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0293326&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10599502","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10599502","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10599502/pdf/pone.0293326.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLoS One","raw_type":"Text"},{"id":"pmid:37878637","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37878637","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PloS one","raw_type":"Journal Article"},{"id":"pmh:oai:art.torvergata.it:2108/359843","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/2108/359843","pdf_url":"https://art.torvergata.it/bitstream/2108/359843/2/journal.pone.0293326.pdf","source":{"id":"https://openalex.org/S4306400993","display_name":"Cineca Institutional Research Information System (Tor Vergata University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I116067653","host_organization_name":"University of Rome Tor Vergata","host_organization_lineage":["https://openalex.org/I116067653"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:c375d9e521fe4a708add93216d31a2f3","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/c375d9e521fe4a708add93216d31a2f3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PLoS ONE, Vol 18, Iss 10, p e0293326 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1371/journal.pone.0293326","doi":"https://doi.org/10.1371/journal.pone.0293326","is_oa":true,"landing_page_url":"http://dx.doi.org/10.1371/journal.pone.0293326","pdf_url":"https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0293326&type=printable","source":{"id":"https://openalex.org/S202381698","display_name":"PLoS ONE","issn_l":"1932-6203","issn":["1932-6203"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315706","host_organization_name":"Public Library of Science","host_organization_lineage":["https://openalex.org/P4310315706"],"host_organization_lineage_names":["Public Library of Science"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PLOS ONE","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[{"id":"https://openalex.org/G6122298034","display_name":null,"funder_award_id":"TMA 1027","funder_id":"https://openalex.org/F4320338462","funder_display_name":"European and Developing Countries Clinical Trials Partnership"}],"funders":[{"id":"https://openalex.org/F4320338462","display_name":"European and Developing Countries Clinical Trials Partnership","ror":"https://ror.org/031jv9v19"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387948817.pdf","grobid_xml":"https://content.openalex.org/works/W4387948817.grobid-xml"},"referenced_works_count":30,"referenced_works":["https://openalex.org/W1510261777","https://openalex.org/W1883995847","https://openalex.org/W1904518076","https://openalex.org/W1951605797","https://openalex.org/W1998234735","https://openalex.org/W2001728079","https://openalex.org/W2074139927","https://openalex.org/W2075371279","https://openalex.org/W2109861188","https://openalex.org/W2123027218","https://openalex.org/W2144743578","https://openalex.org/W2144975624","https://openalex.org/W2159181197","https://openalex.org/W2162727140","https://openalex.org/W2170231953","https://openalex.org/W2171126517","https://openalex.org/W2173078931","https://openalex.org/W2505603063","https://openalex.org/W2605862165","https://openalex.org/W2766514417","https://openalex.org/W2799524357","https://openalex.org/W2903314774","https://openalex.org/W2965891775","https://openalex.org/W2967264703","https://openalex.org/W2990003986","https://openalex.org/W3007379203","https://openalex.org/W3080504755","https://openalex.org/W3088382535","https://openalex.org/W3128242104","https://openalex.org/W3145717752"],"related_works":["https://openalex.org/W4307313464","https://openalex.org/W4402665308","https://openalex.org/W2953475125","https://openalex.org/W4392409446","https://openalex.org/W4200582004","https://openalex.org/W4385727319","https://openalex.org/W3080504755","https://openalex.org/W3145717752","https://openalex.org/W4391823710","https://openalex.org/W2967264703"],"abstract_inverted_index":{"OBJECTIVE:":[0],"We":[1],"sought":[2],"to":[3,82,207,267],"evaluate":[4],"the":[5,120,126,276],"variability":[6],"of":[7,41,88,197,205,256,272,278],"HIV-1":[8,63,229],"and":[9,43,94,107,137,161,176,180,186,211,219,236,261],"its":[10],"effect":[11],"on":[12,109,141],"immuno-virological":[13,69],"response":[14],"among":[15,31],"adolescents":[16],"living":[17],"with":[18,155,193,202,262],"perinatally":[19],"acquired":[20,100],"HIV":[21],"(APHI).":[22],"METHODS:":[23],"A":[24],"cohort":[25],"study":[26],"was":[27,47,80,114,129,133,143,167,199],"conducted":[28],"from":[29],"2018-2020":[30],"311":[32],"APHI":[33,245],"receiving":[34],"antiretroviral":[35],"therapy":[36],"(ART)":[37],"in":[38,123,246],"Cameroon.":[39],"Sequencing":[40],"protease":[42],"reverse":[44],"transcriptase":[45],"regions":[46],"performed":[48],"for":[49,99],"participants":[50,122,192],"experiencing":[51],"virological":[52],"failure,":[53],"VF,":[54],"(Plasma":[55],"viral":[56,151,241],"load,":[57],"PVL":[58,95,183,212],"\u2265":[59],"1000":[60],"RNA":[61],"copies/ml).":[62],"subtypes":[64],"were":[65,71,153,231],"inferred":[66],"by":[67,259],"phylogeny;":[68],"responses":[70],"monitored":[72],"at":[73],"3-time":[74],"points":[75],"(T1-T3).":[76],"Cox":[77],"regression":[78],"modeling":[79],"used":[81],"estimate":[83],"adjusted":[84,98],"hazard":[85],"ratios":[86],"(aHRs)":[87],"progression":[89,206],"to:":[90],"CD4":[91,170,208],"<":[92,112,209],"250,":[93,210],">":[96,213],"5log10,":[97,214],"drug":[101],"resistance,":[102],"gender,":[103],"ART":[104,142],"line,":[105],"adherence,":[106],"duration":[108,140,196],"treatment;":[110],"p":[111],"0.05":[113,222],"considered":[115],"statistically":[116],"significant.":[117],"RESULTS:":[118],"Of":[119],"141":[121],"VF":[124],"enrolled,":[125],"male-female":[127],"ratio":[128],"1:1;":[130],"mean":[131],"age":[132],"15":[134],"(\u00b13)":[135],"years;":[136],"median":[138],"[IQR]":[139],"51":[144],"[46-60]":[145],"months.":[146],"In":[147],"all":[148],"phases,":[149],"17":[150],"clades":[152,265],"found":[154],"a":[156,239,252],"predominant":[157],"CRF02_AG":[158,194,260],"(58.2%,":[159],"59.4%,":[160],"58.3%).":[162],"From":[163],"T1-T3":[164],"respectively,":[165],"there":[166,250],"an":[168],"increasing":[169],"count":[171],"(213":[172],"[154-313],":[173],"366":[174],"[309-469],":[175],"438":[177],"[364-569]":[178],"cells/mm3)":[179],"decline":[181],"log10":[182],"(5.23,":[184],"4.43,":[185],"4.43),":[187],"similar":[188],"across":[189],"subtypes.":[190],"Among":[191,244],"infection,":[195],"treatment":[198,273],"significantly":[200,274],"associated":[201],"both":[203],"rates":[204],"aHR":[215,220],"=":[216,221],"0.02":[217],"(0.001-0.52),":[218],"(0.01-0.47)":[223],"respectively.":[224],"Moreover,":[225],"four":[226],"potential":[227,263],"new":[228],"recombinants":[230],"identified":[232],"(CRF02_AG/02D,":[233],"CRF02_AG/02A1F2,":[234],"D/CRF02_AG,":[235],"AF2/CRF02_AG),":[237],"indicating":[238],"wide":[240,253],"diversity.":[242],"CONCLUSION:":[243],"settings":[247],"like":[248],"Cameroon,":[249],"is":[251],"genetic":[254],"diversity":[255],"HIV-1,":[257],"driven":[258],"novel":[264],"due":[266],"ongoing":[268],"recombination":[269],"events.":[270],"Duration":[271],"reduces":[275],"risk":[277],"disease":[279],"progression.":[280]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2023-10-27T00:00:00"}
