{"id":"https://openalex.org/W4387939770","doi":"https://doi.org/10.14235/bas.galenos.2023.60566","title":"Quercetin Change the Exosome Secretion and Total miRNA Concentration in Primary (Colo320) and Metastatic (Colo741) Colon Cancer Cell Lines","display_name":"Quercetin Change the Exosome Secretion and Total miRNA Concentration in Primary (Colo320) and Metastatic (Colo741) Colon Cancer Cell Lines","publication_year":2023,"publication_date":"2023-10-25","ids":{"openalex":"https://openalex.org/W4387939770","doi":"https://doi.org/10.14235/bas.galenos.2023.60566"},"language":"en","primary_location":{"id":"doi:10.14235/bas.galenos.2023.60566","doi":"https://doi.org/10.14235/bas.galenos.2023.60566","is_oa":true,"landing_page_url":"https://doi.org/10.14235/bas.galenos.2023.60566","pdf_url":"https://doi.org/10.14235/bas.galenos.2023.60566","source":{"id":"https://openalex.org/S4210191091","display_name":"Bezmialem Science","issn_l":"2148-2373","issn":["2148-2373"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4","tr-dizin"],"host_organization":"https://openalex.org/P4310320331","host_organization_name":"Galenos Yayinevi","host_organization_lineage":["https://openalex.org/P4310320331"],"host_organization_lineage_names":["Galenos Yayinevi"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bezmialem Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.14235/bas.galenos.2023.60566","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077658235","display_name":"Eda Becer","orcid":"https://orcid.org/0000-0002-2378-128X","observed_orcids":["https://orcid.org/0000-0002-2378-128X"]},"institutions":[{"id":"https://openalex.org/I36515993","display_name":"Eastern Mediterranean University","ror":"https://ror.org/00excyz84","country_code":"CY","type":"education","lineage":["https://openalex.org/I36515993"]}],"countries":["CY"],"is_corresponding":false,"raw_author_name":"Eda BECER","raw_affiliation_strings":["Eastern Mediterranean University Faculty of Pharmacy, Famagusta, North Cyprus"],"raw_orcid":"https://orcid.org/0000-0002-2378-128X","affiliations":[{"raw_affiliation_string":"Eastern Mediterranean University Faculty of Pharmacy, Famagusta, North Cyprus","institution_ids":["https://openalex.org/I36515993"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054241758","display_name":"Serpil \u00d6zsoy","orcid":"https://orcid.org/0000-0001-9518-5172","observed_orcids":["https://orcid.org/0000-0001-9518-5172"]},"institutions":[{"id":"https://openalex.org/I69050122","display_name":"Near East University","ror":"https://ror.org/02x8svs93","country_code":"CY","type":"education","lineage":["https://openalex.org/I69050122"]}],"countries":["CY"],"is_corresponding":true,"raw_author_name":"Serpil \u00d6ZSOY","raw_affiliation_strings":["Near East University Faculty of Health Sciences, Department of Nutrition and Dietetics, Nicosia, North Cyprus"],"raw_orcid":"https://orcid.org/0000-0001-9518-5172","affiliations":[{"raw_affiliation_string":"Near East University Faculty of Health Sciences, Department of Nutrition and Dietetics, Nicosia, North Cyprus","institution_ids":["https://openalex.org/I69050122"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028679670","display_name":"Hilal Kabaday\u0131","orcid":"https://orcid.org/0000-0001-7429-1478","observed_orcids":["https://orcid.org/0000-0001-7429-1478"]},"institutions":[{"id":"https://openalex.org/I16748637","display_name":"Manisa Celal Bayar University","ror":"https://ror.org/053f2w588","country_code":"TR","type":"education","lineage":["https://openalex.org/I16748637"]},{"id":"https://openalex.org/I69050122","display_name":"Near East University","ror":"https://ror.org/02x8svs93","country_code":"CY","type":"education","lineage":["https://openalex.org/I69050122"]}],"countries":["CY","TR"],"is_corresponding":false,"raw_author_name":"Hilal KABADAYI","raw_affiliation_strings":["Manisa Celal Bayar University Faculty of Medicine, Department of Histology and Embryology, Manisa, Turkey","Near East University Faculty of Health Sciences , Department of Nutrition and Dietetics , Nicosia , North Cyprus"],"raw_orcid":"https://orcid.org/0000-0001-7429-1478","affiliations":[{"raw_affiliation_string":"Manisa Celal Bayar University Faculty of Medicine, Department of Histology and Embryology, Manisa, Turkey","institution_ids":["https://openalex.org/I16748637"]},{"raw_affiliation_string":"Near East University Faculty of Health Sciences , Department of Nutrition and Dietetics , Nicosia , North Cyprus","institution_ids":["https://openalex.org/I69050122"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5080110655","display_name":"Hafize Seda Vatansever","orcid":"https://orcid.org/0000-0003-3619-5666","observed_orcids":["https://orcid.org/0000-0003-3619-5666"]},"institutions":[{"id":"https://openalex.org/I69050122","display_name":"Near East University","ror":"https://ror.org/02x8svs93","country_code":"CY","type":"education","lineage":["https://openalex.org/I69050122"]}],"countries":["CY"],"is_corresponding":false,"raw_author_name":"Hafize Seda VATANSEVER","raw_affiliation_strings":["Near East University, DESAM Research Institute, Nicosia, North Cyprus"],"raw_orcid":"https://orcid.org/0000-0003-3619-5666","affiliations":[{"raw_affiliation_string":"Near East University, DESAM Research Institute, Nicosia, North Cyprus","institution_ids":["https://openalex.org/I69050122"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5054241758"],"corresponding_institution_ids":["https://openalex.org/I69050122"],"apc_list":null,"apc_paid":null,"fwci":0.1775,"has_fulltext":true,"cited_by_count":2,"citation_normalized_percentile":{"value":0.39488277,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"11","issue":"4","first_page":"335","last_page":"342"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10773","display_name":"Extracellular vesicles in disease","score":0.9887999892234802,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.0071000000461936,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12582","display_name":"Flavonoids in Medical Research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/quercetin","display_name":"quercetin","score":1.0},{"id":"https://openalex.org/keywords/exosomes","display_name":"exosomes","score":0.9480000138282776},{"id":"https://openalex.org/keywords/extracellular-vesicles","display_name":"extracellular vesicles","score":0.8870000243186951},{"id":"https://openalex.org/keywords/exosomal-mirna","display_name":"exosomal microRNAs","score":0.8009999990463257},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.9419999718666077},{"id":"https://openalex.org/keywords/dicer","display_name":"Dicer","score":0.8259999752044678},{"id":"https://openalex.org/keywords/argonaute-2","display_name":"Argonaute 2","score":0.9340000152587891},{"id":"https://openalex.org/keywords/eif2alpha","display_name":"eIF2\u03b1","score":0.9810000061988831},{"id":"https://openalex.org/keywords/cd9","display_name":"CD9","score":0.9940000176429749},{"id":"https://openalex.org/keywords/cd63","display_name":"CD63","score":1.0},{"id":"https://openalex.org/keywords/polyphenols","display_name":"polyphenols","score":0.7540000081062317},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8240000009536743},{"id":"https://openalex.org/keywords/metastatic-colon-cancer","display_name":"metastatic colon cancer","score":0.8230000138282776},{"id":"https://openalex.org/keywords/cancer-prevention","display_name":"cancer prevention","score":0.3790000081062317},{"id":"https://openalex.org/keywords/natural-compounds","display_name":"natural compounds","score":0.40700000524520874}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8797911405563354},{"id":"https://openalex.org/C2781261824","wikidata":"https://www.wikidata.org/wiki/Q903634","display_name":"Exosome","level":5,"score":0.7786962985992432},{"id":"https://openalex.org/C20518536","wikidata":"https://www.wikidata.org/wiki/Q6840469","display_name":"Microvesicles","level":4,"score":0.700482189655304},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.6463420391082764},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6092567443847656},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5603160858154297},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5077217817306519},{"id":"https://openalex.org/C526805850","wikidata":"https://www.wikidata.org/wiki/Q188874","display_name":"Colorectal cancer","level":3,"score":0.48449966311454773},{"id":"https://openalex.org/C2781263971","wikidata":"https://www.wikidata.org/wiki/Q409478","display_name":"Quercetin","level":3,"score":0.4547998905181885},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42488616704940796},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.41970276832580566},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.11176028847694397},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07718020677566528},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.054290592670440674},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.14235/bas.galenos.2023.60566","doi":"https://doi.org/10.14235/bas.galenos.2023.60566","is_oa":true,"landing_page_url":"https://doi.org/10.14235/bas.galenos.2023.60566","pdf_url":"https://doi.org/10.14235/bas.galenos.2023.60566","source":{"id":"https://openalex.org/S4210191091","display_name":"Bezmialem Science","issn_l":"2148-2373","issn":["2148-2373"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4","tr-dizin"],"host_organization":"https://openalex.org/P4310320331","host_organization_name":"Galenos Yayinevi","host_organization_lineage":["https://openalex.org/P4310320331"],"host_organization_lineage_names":["Galenos Yayinevi"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bezmialem Science","raw_type":"journal-article"},{"id":"pmh:6a7d2238-a845-4a07-ae9f-d25563d2806e","doi":null,"is_oa":false,"landing_page_url":"https://avesis.aybu.edu.tr/publication/details/6a7d2238-a845-4a07-ae9f-d25563d2806e/oai","pdf_url":null,"source":{"id":"https://openalex.org/S7407055213","display_name":"AYBU AVESIS","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:74d92e48352242fea27eba6afe933fa9","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/74d92e48352242fea27eba6afe933fa9","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Bezmi\u00e2lem Science, Vol 11, Iss 4, Pp 335-342 (2023)","raw_type":"article"},{"id":"pmh:oai:i-rep.emu.edu.tr:11129/10436","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11129/10436","pdf_url":null,"source":{"id":"https://openalex.org/S4306402300","display_name":"Eastern Mediterranean University Institutional Repository (Eastern Mediterranean University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I36515993","host_organization_name":"Eastern Mediterranean University","host_organization_lineage":["https://openalex.org/I36515993"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.14235/bas.galenos.2023.60566","doi":"https://doi.org/10.14235/bas.galenos.2023.60566","is_oa":true,"landing_page_url":"https://doi.org/10.14235/bas.galenos.2023.60566","pdf_url":"https://doi.org/10.14235/bas.galenos.2023.60566","source":{"id":"https://openalex.org/S4210191091","display_name":"Bezmialem Science","issn_l":"2148-2373","issn":["2148-2373"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj","poland-20","russia-white-list-4","tr-dizin"],"host_organization":"https://openalex.org/P4310320331","host_organization_name":"Galenos Yayinevi","host_organization_lineage":["https://openalex.org/P4310320331"],"host_organization_lineage_names":["Galenos Yayinevi"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bezmialem Science","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387939770.pdf","grobid_xml":"https://content.openalex.org/works/W4387939770.grobid-xml"},"referenced_works_count":27,"referenced_works":["https://openalex.org/W1915983093","https://openalex.org/W1971104968","https://openalex.org/W2017778091","https://openalex.org/W2040663962","https://openalex.org/W2045335791","https://openalex.org/W2056776171","https://openalex.org/W2140553597","https://openalex.org/W2155660899","https://openalex.org/W2155705118","https://openalex.org/W2167587083","https://openalex.org/W2170008613","https://openalex.org/W2186642407","https://openalex.org/W2187610091","https://openalex.org/W2227255764","https://openalex.org/W2404631791","https://openalex.org/W2508553839","https://openalex.org/W2760469121","https://openalex.org/W2890163759","https://openalex.org/W2906259203","https://openalex.org/W2921295182","https://openalex.org/W2923581883","https://openalex.org/W3019096579","https://openalex.org/W3143120081","https://openalex.org/W3167773023","https://openalex.org/W3180846246","https://openalex.org/W4210675720","https://openalex.org/W4243386260"],"related_works":["https://openalex.org/W4282840898","https://openalex.org/W2610533097","https://openalex.org/W7221012101","https://openalex.org/W2376575370","https://openalex.org/W2530930349","https://openalex.org/W2355259601","https://openalex.org/W2125054151","https://openalex.org/W1586281925","https://openalex.org/W3015500267","https://openalex.org/W2529267350"],"abstract_inverted_index":{"Objective:":[0],"Quercetin,":[1],"which":[2],"is":[3,15,90],"considered":[4],"a":[5,91,110],"potential":[6],"anti-cancer":[7],"agent":[8],"in":[9,66,129,134,164],"the":[10,48,85,98,113,120,151],"prevention":[11],"of":[12,17,50,87,101,122,143],"colon":[13,70],"cancer,":[14],"one":[16],"its":[18],"natural":[19],"polyphenolic":[20],"compounds.Extracellular":[21],"vesicles,":[22],"such":[23],"as":[24],"exosomes,":[25],"secreted":[26],"from":[27],"cells":[28],"and":[29,55,57,64,68,127,131,145,168],"their":[30,58],"components":[31],"contribute":[32],"to":[33,46,83,96,150],"cellular":[34],"behavioral":[35],"characteristics":[36],"by":[37,109],"transporting":[38],"proteins":[39],"or":[40],"miRNAs.In":[41],"this":[42],"study,":[43],"we":[44],"aimed":[45],"determine":[47],"cytotoxicity":[49,86],"Dicer,":[51,123,214,240],"Ago2,":[52,124,215,241],"eIF2\u03b1":[53,144,216],"CD9":[54,146,217,243,263],"CD63":[56,128],"effects":[59],"on":[60],"exosomal":[61,159],"miRNA":[62,133,160,223,274],"secretion":[63],"expression":[65],"Colo320":[67,130,207,279],"Colo741":[69,152,169,209,265,282],"cancer":[71],"cell":[72],"lines":[73],"applied":[74,95],"quercetin.":[75],"Methods:The":[76],"3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium":[77],"bromide":[78],"(MTT)":[79],"assay":[80],"was":[81,104,117,136],"used":[82,118],"analyze":[84],"quercetin.MTT":[88],"analysis":[89,93],"colorimetric":[92],"method":[94],"measure":[97],"metabolic":[99],"activity":[100],"cells.The":[102],"absorbance":[103],"measured":[105],"at":[106],"570":[107],"nm":[108],"spectrophotometer.Besides":[111],"that,":[112],"indirect":[114],"immunoperoxidase":[115],"staining":[116],"for":[119],"distribution":[121],"eIF2\u03b1,":[125],"CD9,":[126],"Colo741.Total":[132],"exosome":[135],"determined":[137],"with":[138],"miRCURY\u2122":[139,254],"Kit.Results:":[140],"The":[141],"immunoreactivities":[142],"significantly":[147],"differed":[148],"compared":[149],"control":[153],"group":[154],"after":[155],"quercetin":[156,166],"application.In":[157],"addition,":[158],"concentrations":[161],"were":[162],"higher":[163],"both":[165],"applied-Colo320":[167],"cells.Ama\u00e7:":[170],"Kolon":[171],"kanserinin":[172],"\u00f6nlenmesinde":[173],"potansiyel":[174],"bir":[175],"anti-kanser":[176],"ajan":[177],"olarak":[178],"kabul":[179],"edilen":[180],"kersetin,":[181],"do\u011fal":[182],"polifenolik":[183],"bile\u015fiklerinden":[184],"biridir.H\u00fccrelerden":[185],"ve":[186,208,218,221,225,238,244,262],"bile\u015fenlerinden":[187],"salg\u0131lanan":[188],"eksozom":[189],"gibi":[190],"h\u00fccre":[191,212],"d\u0131\u015f\u0131":[192],"vezik\u00fcller,":[193],"proteinleri":[194],"veya":[195],"miRNA'lar\u0131":[196],"ta\u015f\u0131ma":[197],"yoluyla":[198],"h\u00fccresel":[199],"davran\u0131\u015f":[200],"\u00f6zelliklerine":[201],"katk\u0131da":[202],"bulunur.Bu":[203],"\u00e7al\u0131\u015fmada,":[204],"kersetin":[205,277],"uygulanan":[206,278],"kolon":[210],"kanseri":[211],"dizilerinde":[213],"CD63'\u00fcn":[219,245],"sitotoksisitesini":[220],"eksozomal":[222,273],"salg\u0131lanmas\u0131":[224],"ekspresyonu":[226],"\u00fczerine":[227],"etkilerini":[228],"belirlemeyi":[229],"ama\u00e7lad\u0131k.Y\u00f6ntemler:":[230],"Kersetin":[231,258],"sitotoksisitesinin":[232],"analizi":[233],"i\u00e7in":[234,247],"MTT":[235],"testi":[236],"kullan\u0131ld\u0131.Colo320":[237],"Colo741'de":[239],"eIF2a,":[242],"da\u011f\u0131t\u0131m\u0131":[246],"dolayl\u0131":[248],"imm\u00fcnoperoksidaz":[249],"boyamas\u0131":[250],"kullan\u0131ld\u0131.Eksozomdaki":[251],"toplam":[252],"miRNA,":[253],"Kit":[255],"ile":[256],"belirlendi.Bulgular:":[257],"uygulamas\u0131ndan":[259],"sonra":[260],"eIF2a":[261],"imm\u00fcnoreaktiviteleri":[264],"kontrol":[266],"grubuna":[267],"k\u0131yasla":[268],"\u00f6nemli":[269],"\u00f6l\u00e7\u00fcde":[270],"farkl\u0131l\u0131k":[271],"g\u00f6sterdi.Ayr\u0131ca":[272],"konsantrasyonlar\u0131":[275],"hem":[276,280],"de":[281],"h\u00fccrelerinde":[283],"daha":[284],"y\u00fcksekti.":[285]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2023-10-26T00:00:00"}