{"id":"https://openalex.org/W4387937712","doi":"https://doi.org/10.3390/molecules28217262","title":"The Green Tea Polyphenol Epigallocatechin-Gallate (EGCG) Interferes with Microcin E492 Amyloid Formation","display_name":"The Green Tea Polyphenol Epigallocatechin-Gallate (EGCG) Interferes with Microcin E492 Amyloid Formation","publication_year":2023,"publication_date":"2023-10-25","ids":{"openalex":"https://openalex.org/W4387937712","doi":"https://doi.org/10.3390/molecules28217262","pmid":"https://pubmed.ncbi.nlm.nih.gov/37959682","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/10648153"},"language":"en","primary_location":{"id":"doi:10.3390/molecules28217262","doi":"https://doi.org/10.3390/molecules28217262","is_oa":true,"landing_page_url":"https://doi.org/10.3390/molecules28217262","pdf_url":"https://www.mdpi.com/1420-3049/28/21/7262/pdf?version=1698225900","source":{"id":"https://openalex.org/S108911230","display_name":"Molecules","issn_l":"1420-3049","issn":["1420-3049","1433-1373"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1420-3049/28/21/7262/pdf?version=1698225900","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Paulina Aguilera","orcid":"https://orcid.org/0000-0001-8780-0999","observed_orcids":["https://orcid.org/0000-0001-8780-0999"]},"institutions":[{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Paulina Aguilera","raw_affiliation_strings":["Grupo de Microbiolog\u00eda Integrativa, Laboratorio de Biolog\u00eda Estructural y Molecular BEM, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425 \u00d1u\u00f1oa, Santiago 7800003, Chile"],"raw_orcid":"https://orcid.org/0000-0001-8780-0999","affiliations":[{"raw_affiliation_string":"Grupo de Microbiolog\u00eda Integrativa, Laboratorio de Biolog\u00eda Estructural y Molecular BEM, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425 \u00d1u\u00f1oa, Santiago 7800003, Chile","institution_ids":["https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073372618","display_name":"Camilo Berr\u00edos-Past\u00e9n","orcid":"https://orcid.org/0000-0001-7780-0856","observed_orcids":["https://orcid.org/0000-0001-7780-0856"]},"institutions":[{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Camilo Berr\u00edos-Past\u00e9n","raw_affiliation_strings":["Grupo de Microbiolog\u00eda Integrativa, Laboratorio de Biolog\u00eda Estructural y Molecular BEM, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425 \u00d1u\u00f1oa, Santiago 7800003, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Microbiolog\u00eda Integrativa, Laboratorio de Biolog\u00eda Estructural y Molecular BEM, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425 \u00d1u\u00f1oa, Santiago 7800003, Chile","institution_ids":["https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112169760","display_name":"Marcelo Veloso","orcid":"https://orcid.org/0009-0006-8810-2248","observed_orcids":["https://orcid.org/0009-0006-8810-2248"]},"institutions":[{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Marcelo Veloso","raw_affiliation_strings":["Grupo de Microbiolog\u00eda Integrativa, Laboratorio de Biolog\u00eda Estructural y Molecular BEM, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425 \u00d1u\u00f1oa, Santiago 7800003, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Microbiolog\u00eda Integrativa, Laboratorio de Biolog\u00eda Estructural y Molecular BEM, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425 \u00d1u\u00f1oa, Santiago 7800003, Chile","institution_ids":["https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5092891841","display_name":"Mat\u00edas G\u00e1lvez-Silva","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Mat\u00edas G\u00e1lvez-Silva","raw_affiliation_strings":["Grupo de Microbiolog\u00eda Integrativa, Laboratorio de Biolog\u00eda Estructural y Molecular BEM, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425 \u00d1u\u00f1oa, Santiago 7800003, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Microbiolog\u00eda Integrativa, Laboratorio de Biolog\u00eda Estructural y Molecular BEM, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425 \u00d1u\u00f1oa, Santiago 7800003, Chile","institution_ids":["https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039523974","display_name":"Florian Turbant","orcid":"https://orcid.org/0000-0001-7376-6937","observed_orcids":["https://orcid.org/0000-0001-7376-6937"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I2801148539","display_name":"Synchrotron SOLEIL","ror":"https://ror.org/01ydb3330","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I2801148539","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I2801360556","display_name":"CEA Paris-Saclay - Etablissement de Saclay","ror":"https://ror.org/01fv25t22","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I2801360556","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210115652","display_name":"Laboratoire L\u00e9on Brillouin","ror":"https://ror.org/029rmm934","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I2738703131","https://openalex.org/I4210091594","https://openalex.org/I4210098836","https://openalex.org/I4210113668","https://openalex.org/I4210115652"]},{"id":"https://openalex.org/I4210128565","display_name":"CEA Paris-Saclay","ror":"https://ror.org/03n15ch10","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I4210128565"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Florian Turbant","raw_affiliation_strings":["Laboratoire L\u00e9on Brillouin LLB, CEA, CNRS UMR12, Universit\u00e9 Paris-Saclay, CEA Saclay, 91191 Gif-sur-Yvette, France","Synchrotron SOLEIL, L\u2019Orme des Merisiers, Saint Aubin BP48, 91192 Gif-sur-Yvette, France"],"raw_orcid":"https://orcid.org/0000-0001-7376-6937","affiliations":[{"raw_affiliation_string":"Laboratoire L\u00e9on Brillouin LLB, CEA, CNRS UMR12, Universit\u00e9 Paris-Saclay, CEA Saclay, 91191 Gif-sur-Yvette, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I2801360556","https://openalex.org/I4210115652","https://openalex.org/I4210128565"]},{"raw_affiliation_string":"Synchrotron SOLEIL, L\u2019Orme des Merisiers, Saint Aubin BP48, 91192 Gif-sur-Yvette, France","institution_ids":["https://openalex.org/I2801148539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103139013","display_name":"Rosalba Lagos","orcid":"https://orcid.org/0000-0001-7543-8769","observed_orcids":["https://orcid.org/0000-0001-7543-8769"]},"institutions":[{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":false,"raw_author_name":"Rosalba Lagos","raw_affiliation_strings":["Grupo de Microbiolog\u00eda Integrativa, Laboratorio de Biolog\u00eda Estructural y Molecular BEM, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425 \u00d1u\u00f1oa, Santiago 7800003, Chile"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Grupo de Microbiolog\u00eda Integrativa, Laboratorio de Biolog\u00eda Estructural y Molecular BEM, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425 \u00d1u\u00f1oa, Santiago 7800003, Chile","institution_ids":["https://openalex.org/I69737025"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053324208","display_name":"Frank Wien","orcid":"https://orcid.org/0000-0002-0752-8735","observed_orcids":["https://orcid.org/0000-0002-0752-8735"]},"institutions":[{"id":"https://openalex.org/I2801148539","display_name":"Synchrotron SOLEIL","ror":"https://ror.org/01ydb3330","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I2801148539","https://openalex.org/I4210128565"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Frank Wien","raw_affiliation_strings":["Synchrotron SOLEIL, L\u2019Orme des Merisiers, Saint Aubin BP48, 91192 Gif-sur-Yvette, France"],"raw_orcid":"https://orcid.org/0000-0002-0752-8735","affiliations":[{"raw_affiliation_string":"Synchrotron SOLEIL, L\u2019Orme des Merisiers, Saint Aubin BP48, 91192 Gif-sur-Yvette, France","institution_ids":["https://openalex.org/I2801148539"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055374611","display_name":"V\u00e9ronique Arluison","orcid":"https://orcid.org/0000-0003-4056-7282","observed_orcids":["https://orcid.org/0000-0003-4056-7282"]},"institutions":[{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I204730241","display_name":"Universit\u00e9 Paris Cit\u00e9","ror":"https://ror.org/05f82e368","country_code":"FR","type":"education","lineage":["https://openalex.org/I204730241"]},{"id":"https://openalex.org/I2738703131","display_name":"Commissariat \u00e0 l'\u00c9nergie Atomique et aux \u00c9nergies Alternatives","ror":"https://ror.org/00jjx8s55","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131"]},{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I2801360556","display_name":"CEA Paris-Saclay - Etablissement de Saclay","ror":"https://ror.org/01fv25t22","country_code":"FR","type":"facility","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I2801360556","https://openalex.org/I4210128565"]},{"id":"https://openalex.org/I4210115652","display_name":"Laboratoire L\u00e9on Brillouin","ror":"https://ror.org/029rmm934","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I2738703131","https://openalex.org/I4210091594","https://openalex.org/I4210098836","https://openalex.org/I4210113668","https://openalex.org/I4210115652"]},{"id":"https://openalex.org/I4210128565","display_name":"CEA Paris-Saclay","ror":"https://ror.org/03n15ch10","country_code":"FR","type":"government","lineage":["https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I4210128565"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Veronique Arluison","raw_affiliation_strings":["Laboratoire L\u00e9on Brillouin LLB, CEA, CNRS UMR12, Universit\u00e9 Paris-Saclay, CEA Saclay, 91191 Gif-sur-Yvette, France","UFR Sciences du Vivant, Universit\u00e9 Paris Cit\u00e9, 75006 Paris, France"],"raw_orcid":"https://orcid.org/0000-0003-4056-7282","affiliations":[{"raw_affiliation_string":"Laboratoire L\u00e9on Brillouin LLB, CEA, CNRS UMR12, Universit\u00e9 Paris-Saclay, CEA Saclay, 91191 Gif-sur-Yvette, France","institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I2801360556","https://openalex.org/I4210115652","https://openalex.org/I4210128565"]},{"raw_affiliation_string":"UFR Sciences du Vivant, Universit\u00e9 Paris Cit\u00e9, 75006 Paris, France","institution_ids":["https://openalex.org/I204730241"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039375365","display_name":"Andr\u00e9s E. Marcoleta","orcid":"https://orcid.org/0000-0003-2950-7510","observed_orcids":["https://orcid.org/0000-0003-2950-7510"]},"institutions":[{"id":"https://openalex.org/I69737025","display_name":"University of Chile","ror":"https://ror.org/047gc3g35","country_code":"CL","type":"education","lineage":["https://openalex.org/I69737025"]}],"countries":["CL"],"is_corresponding":true,"raw_author_name":"Andr\u00e9s E. Marcoleta","raw_affiliation_strings":["Grupo de Microbiolog\u00eda Integrativa, Laboratorio de Biolog\u00eda Estructural y Molecular BEM, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425 \u00d1u\u00f1oa, Santiago 7800003, Chile"],"raw_orcid":"https://orcid.org/0000-0003-2950-7510","affiliations":[{"raw_affiliation_string":"Grupo de Microbiolog\u00eda Integrativa, Laboratorio de Biolog\u00eda Estructural y Molecular BEM, Facultad de Ciencias, Universidad de Chile, Las Palmeras 3425 \u00d1u\u00f1oa, Santiago 7800003, Chile","institution_ids":["https://openalex.org/I69737025"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5039375365","https://openalex.org/A5055374611"],"corresponding_institution_ids":["https://openalex.org/I1294671590","https://openalex.org/I204730241","https://openalex.org/I2738703131","https://openalex.org/I277688954","https://openalex.org/I2801360556","https://openalex.org/I4210115652","https://openalex.org/I4210128565","https://openalex.org/I69737025"],"apc_list":{"value":2300,"currency":"CHF","value_usd":2558},"apc_paid":{"value":2300,"currency":"CHF","value_usd":2558},"fwci":0.7465,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.63058919,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":98},"biblio":{"volume":"28","issue":"21","first_page":"7262","last_page":"7262"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.5746999979019165,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.5746999979019165,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11411","display_name":"Tea Polyphenols and Effects","score":0.2992999851703644,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11335","display_name":"Prion Diseases and Protein Misfolding","score":0.019500000402331352,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/epigallocatechin-gallate","display_name":"epigallocatechin gallate","score":0.9829999804496765},{"id":"https://openalex.org/keywords/green-tea-polyphenols","display_name":"green tea polyphenols","score":0.8259999752044678},{"id":"https://openalex.org/keywords/microcin-e492","display_name":"microcin E492","score":0.9860000014305115},{"id":"https://openalex.org/keywords/amyloid-formation-inhibition","display_name":"amyloid formation inhibition","score":0.6729999780654907},{"id":"https://openalex.org/keywords/bacterial-amyloids","display_name":"bacterial amyloids","score":0.8209999799728394},{"id":"https://openalex.org/keywords/protein-aggregation-kinetics","display_name":"protein aggregation kinetics","score":0.5910000205039978},{"id":"https://openalex.org/keywords/beta-sheet","display_name":"beta-sheet","score":0.8769999742507935},{"id":"https://openalex.org/keywords/thermal-stability","display_name":"thermal stability","score":0.5730000138282776},{"id":"https://openalex.org/keywords/antibacterial-peptides","display_name":"antibacterial peptides","score":0.699999988079071},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.6520000100135803},{"id":"https://openalex.org/keywords/amorphous-aggregates","display_name":"amorphous aggregates","score":0.6850000023841858}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7588449716567993},{"id":"https://openalex.org/C133571119","wikidata":"https://www.wikidata.org/wiki/Q899102","display_name":"Circular dichroism","level":2,"score":0.7049369215965271},{"id":"https://openalex.org/C2778896982","wikidata":"https://www.wikidata.org/wiki/Q2033625","display_name":"Thioflavin","level":4,"score":0.6761773824691772},{"id":"https://openalex.org/C2777192995","wikidata":"https://www.wikidata.org/wiki/Q393339","display_name":"Epigallocatechin gallate","level":4,"score":0.6566840410232544},{"id":"https://openalex.org/C2777633098","wikidata":"https://www.wikidata.org/wiki/Q2736051","display_name":"Amyloid (mycology)","level":2,"score":0.6497737169265747},{"id":"https://openalex.org/C62614982","wikidata":"https://www.wikidata.org/wiki/Q904984","display_name":"Protein secondary structure","level":2,"score":0.5901579260826111},{"id":"https://openalex.org/C2780295536","wikidata":"https://www.wikidata.org/wiki/Q11682030","display_name":"Gallate","level":2,"score":0.5772014260292053},{"id":"https://openalex.org/C70899900","wikidata":"https://www.wikidata.org/wiki/Q290439","display_name":"Polyphenol","level":3,"score":0.5698909759521484},{"id":"https://openalex.org/C2779054382","wikidata":"https://www.wikidata.org/wiki/Q72185287","display_name":"Flavonoid","level":3,"score":0.5087905526161194},{"id":"https://openalex.org/C2779281246","wikidata":"https://www.wikidata.org/wiki/Q172847","display_name":"Peptide","level":2,"score":0.46103525161743164},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.45879197120666504},{"id":"https://openalex.org/C2780104969","wikidata":"https://www.wikidata.org/wiki/Q4774530","display_name":"Antibacterial activity","level":3,"score":0.44592300057411194},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.42781010270118713},{"id":"https://openalex.org/C4937899","wikidata":"https://www.wikidata.org/wiki/Q68541106","display_name":"Antimicrobial","level":2,"score":0.42340773344039917},{"id":"https://openalex.org/C136238340","wikidata":"https://www.wikidata.org/wiki/Q7251455","display_name":"Protein aggregation","level":2,"score":0.4185534715652466},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.17226511240005493},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.12253439426422119},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.10092219710350037},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09840467572212219},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.09069234132766724},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.08654749393463135},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000682","descriptor_name":"Amyloid","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D001430","descriptor_name":"Bacteriocins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002392","descriptor_name":"Catechin","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D002392","descriptor_name":"Catechin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002392","descriptor_name":"Catechin","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013662","descriptor_name":"Tea","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058227","descriptor_name":"Amyloidogenic Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059808","descriptor_name":"Polyphenols","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true}],"locations_count":6,"locations":[{"id":"doi:10.3390/molecules28217262","doi":"https://doi.org/10.3390/molecules28217262","is_oa":true,"landing_page_url":"https://doi.org/10.3390/molecules28217262","pdf_url":"https://www.mdpi.com/1420-3049/28/21/7262/pdf?version=1698225900","source":{"id":"https://openalex.org/S108911230","display_name":"Molecules","issn_l":"1420-3049","issn":["1420-3049","1433-1373"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:10648153","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/10648153","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC10648153/pdf/molecules-28-07262.pdf","source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules","raw_type":"Text"},{"id":"pmid:37959682","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/37959682","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:repositorio.uchile.cl:2250/213785","doi":null,"is_oa":true,"landing_page_url":"https://repositorio.uchile.cl/handle/2250/213785","pdf_url":"https://repositorio.uchile.cl/bitstream/2250/213785/-1/molecules-28-07262.pdf","source":{"id":"https://openalex.org/S4306481413","display_name":"Universidad de Chile","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecules","raw_type":"Art\u00edculo de revista"},{"id":"pmh:oai:HAL:hal-04353191v1","doi":null,"is_oa":false,"landing_page_url":"https://hal.science/hal-04353191","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecules, 2023, 28 (21), ⟨10.3390/molecules28217262⟩","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:doaj.org/article:b678fe453866461d907199265ca091c3","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/b678fe453866461d907199265ca091c3","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Molecules, Vol 28, Iss 21, p 7262 (2023)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/molecules28217262","doi":"https://doi.org/10.3390/molecules28217262","is_oa":true,"landing_page_url":"https://doi.org/10.3390/molecules28217262","pdf_url":"https://www.mdpi.com/1420-3049/28/21/7262/pdf?version=1698225900","source":{"id":"https://openalex.org/S108911230","display_name":"Molecules","issn_l":"1420-3049","issn":["1420-3049","1433-1373"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","medline","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecules","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6000000238418579,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3024506935","display_name":"Idex Paris-Saclay","funder_award_id":"ANR-11-IDEX-0003","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"},{"id":"https://openalex.org/G3094824330","display_name":null,"funder_award_id":"ANR-18-IDEX-0001","funder_id":"https://openalex.org/F4320338073","funder_display_name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico"},{"id":"https://openalex.org/G40490432","display_name":null,"funder_award_id":"1221193","funder_id":"https://openalex.org/F4320338073","funder_display_name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico"},{"id":"https://openalex.org/G4568280355","display_name":null,"funder_award_id":"FONDECYT 1221193","funder_id":"https://openalex.org/F4320331146","funder_display_name":"Agencia Nacional de Investigaci\u00f3n y Desarrollo"},{"id":"https://openalex.org/G6976250424","display_name":null,"funder_award_id":"C19S02","funder_id":"https://openalex.org/F4320338073","funder_display_name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico"},{"id":"https://openalex.org/G8026543575","display_name":null,"funder_award_id":"ANR-11-IDEX-0003-02","funder_id":"https://openalex.org/F4320338073","funder_display_name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico"}],"funders":[{"id":"https://openalex.org/F4320312369","display_name":"Society for Research in Child Development","ror":"https://ror.org/05w06bw34"},{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"},{"id":"https://openalex.org/F4320331146","display_name":"Agencia Nacional de Investigaci\u00f3n y Desarrollo","ror":"https://ror.org/05btm5233"},{"id":"https://openalex.org/F4320338073","display_name":"Fondo Nacional de Desarrollo Cient\u00edfico y Tecnol\u00f3gico","ror":"https://ror.org/02ap3w078"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4387937712.pdf","grobid_xml":"https://content.openalex.org/works/W4387937712.grobid-xml"},"referenced_works_count":48,"referenced_works":["https://openalex.org/W1975085160","https://openalex.org/W1976201852","https://openalex.org/W1984118861","https://openalex.org/W1995319721","https://openalex.org/W1996367109","https://openalex.org/W2006499817","https://openalex.org/W2009890320","https://openalex.org/W2020069228","https://openalex.org/W2021785060","https://openalex.org/W2031007679","https://openalex.org/W2035654684","https://openalex.org/W2086603752","https://openalex.org/W2104700141","https://openalex.org/W2122675979","https://openalex.org/W2142038032","https://openalex.org/W2147297400","https://openalex.org/W2148382161","https://openalex.org/W2161371008","https://openalex.org/W2262600295","https://openalex.org/W2301345562","https://openalex.org/W2465530239","https://openalex.org/W2529312233","https://openalex.org/W2540273365","https://openalex.org/W2560598375","https://openalex.org/W2601083114","https://openalex.org/W2614053601","https://openalex.org/W2783961388","https://openalex.org/W2793431243","https://openalex.org/W2806838148","https://openalex.org/W2808618567","https://openalex.org/W2884441462","https://openalex.org/W2894868033","https://openalex.org/W2903278981","https://openalex.org/W2913336017","https://openalex.org/W2964896323","https://openalex.org/W3007609761","https://openalex.org/W3041353096","https://openalex.org/W3092260414","https://openalex.org/W3092376061","https://openalex.org/W3140400896","https://openalex.org/W4214568954","https://openalex.org/W4214692139","https://openalex.org/W4290993388","https://openalex.org/W4290995106","https://openalex.org/W4291019148","https://openalex.org/W4291019362","https://openalex.org/W4313259898","https://openalex.org/W4380886827"],"related_works":["https://openalex.org/W3007159658","https://openalex.org/W4376127430","https://openalex.org/W2328878803","https://openalex.org/W2998557779","https://openalex.org/W3038046470","https://openalex.org/W3034211886","https://openalex.org/W3081195611","https://openalex.org/W746264459","https://openalex.org/W2499136986","https://openalex.org/W1849929173"],"abstract_inverted_index":{"strains,":[0],"which,":[1],"under":[2],"certain":[3],"conditions,":[4],"form":[5],"amyloid":[6,67,80,177],"fibers,":[7],"leading":[8],"to":[9,63,78,102,150],"the":[10,27,35,53,56,83,104,122,125,142,155,176],"loss":[11],"of":[12,38,55,87,111,124,141,175,179],"its":[13,32],"antibacterial":[14],"activity.":[15],"Although":[16],"this":[17,42,49],"protein":[18],"has":[19],"been":[20,46],"characterized":[21],"as":[22],"a":[23,147],"model":[24],"functional":[25],"amyloid,":[26,127],"secondary":[28,105],"structure":[29],"transitions":[30],"behind":[31],"formation,":[33],"and":[34,95,109,133,146,181],"possible":[36],"effect":[37],"molecules":[39],"that":[40,118,154],"inhibit":[41],"process,":[43],"have":[44],"not":[45,166],"investigated.":[47],"In":[48],"study,":[50],"we":[51],"examined":[52],"ability":[54],"green":[57],"tea":[58],"flavonoid":[59],"epigallocatechin":[60],"gallate":[61],"(EGCG)":[62],"interfere":[64],"with":[65],"MccE492":[66,126,180],"formation.":[68],"Aggregation":[69],"kinetics":[70],"followed":[71],"by":[72],"thioflavin":[73],"T":[74],"binding":[75],"were":[76,100],"used":[77,101],"monitor":[79],"formation":[81,123,178],"in":[82,129],"presence":[84],"or":[85,160],"absence":[86],"EGCG.":[88],"Additionally,":[89],"synchrotron":[90],"radiation":[91],"circular":[92],"dichroism":[93],"(SRCD)":[94],"transmission":[96],"electron":[97],"microscopy":[98],"(TEM)":[99],"study":[103],"structure,":[106],"thermal":[107],"stability,":[108],"morphology":[110],"microcin":[112],"E492":[113],"fibers.":[114],"Our":[115],"results":[116],"showed":[117],"EGCG":[119,170],"significantly":[120],"inhibited":[121],"resulting":[128],"mainly":[130],"amorphous":[131],"aggregates":[132,138],"small":[134],"oligomers.":[135],"However,":[136],"these":[137],"retained":[139],"part":[140],"\u03b2-sheet":[143],"SRCD":[144],"signal":[145],"high":[148],"resistance":[149],"heat":[151],"denaturation,":[152],"suggesting":[153],"aggregation":[156],"process":[157],"is":[158,171],"sequestered":[159],"deviated":[161],"at":[162],"some":[163],"stage":[164],"but":[165],"completely":[167],"prevented.":[168],"Thus,":[169],"an":[172],"interesting":[173],"inhibitor":[174],"other":[182],"bacterial":[183],"amyloids.":[184]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2023-10-26T00:00:00"}